| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sameer Mohammad, Rajesh T Patel, Joanne Bruno, Muhammad Siyab Panhwar, Jennifer Wen, Timothy E McGra. A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivity. Molecular and cellular biology. vol 34. issue 19. 2014-11-11. PMID:25047836. |
a naturally occurring gip receptor variant undergoes enhanced agonist-induced desensitization, which impairs gip control of adipose insulin sensitivity. |
2014-11-11 |
2023-08-13 |
Not clear |
| Sameer Mohammad, Rajesh T Patel, Joanne Bruno, Muhammad Siyab Panhwar, Jennifer Wen, Timothy E McGra. A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivity. Molecular and cellular biology. vol 34. issue 19. 2014-11-11. PMID:25047836. |
a naturally occurring variant of gipr (e354q) associated with an increased incidence of insulin resistance, type 2 diabetes, and cardiovascular disease in humans responds to gip stimulation with an exaggerated downregulation from the plasma membrane and a delayed recovery of gip sensitivity following cessation of gip stimulation. |
2014-11-11 |
2023-08-13 |
Not clear |
| M T Lund, S Dalby, B Hartmann, J Helge, J J Holst, F Del. The incretin effect does not differ in trained and untrained, young, healthy men. Acta physiologica (Oxford, England). vol 210. issue 3. 2014-10-24. PMID:24354574. |
the insulin secretion rate is higher after oral compared with intravenous glucose administration due to the release of glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) enhancing the glucose-induced insulin secretion (the incretin effect). |
2014-10-24 |
2023-08-12 |
Not clear |
| Pia V Röder, Kerstin E Geillinger, Tamara S Zietek, Bernard Thorens, Hermann Koepsell, Hannelore Danie. The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing. PloS one. vol 9. issue 2. 2014-10-16. PMID:24587162. |
moreover, we examined the contribution of these transporters to glucose-induced changes in plasma gip, glp-1 and insulin levels. |
2014-10-16 |
2023-08-12 |
mouse |
| Javier T Gonzalez, Emma J Stevenso. Calcium co-ingestion augments postprandial glucose-dependent insulinotropic peptide(1-42), glucagon-like peptide-1 and insulin concentrations in humans. European journal of nutrition. vol 53. issue 2. 2014-10-09. PMID:23689561. |
this study determined whether calcium co-ingestion potentiates postprandial gip(1-42) and glp-1 concentrations in humans and the concomitant impact on insulin, appetite sensations and substrate metabolism. |
2014-10-09 |
2023-08-12 |
Not clear |
| Christine Bernsmeier, Anne C Meyer-Gerspach, Lea S Blaser, Lia Jeker, Robert E Steinert, Markus H Heim, Christoph Beglinge. Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease. PloS one. vol 9. issue 1. 2014-10-06. PMID:24489924. |
the incretins glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are gastrointestinal peptide hormones regulating postprandial insulin release from pancreatic β-cells. |
2014-10-06 |
2023-08-12 |
mouse |
| Michael Taulo Lund, Lærke Taudorf, Bolette Hartmann, Jørn Wulff Helge, Jens Juel Holst, Flemming Del. Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males. European journal of applied physiology. vol 113. issue 11. 2014-09-24. PMID:23979179. |
the insulin and gip responses were markedly lower in t than ut and correlated during the first 30 min after the liquid meal. |
2014-09-24 |
2023-08-12 |
human |
| Michael Taulo Lund, Lærke Taudorf, Bolette Hartmann, Jørn Wulff Helge, Jens Juel Holst, Flemming Del. Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males. European journal of applied physiology. vol 113. issue 11. 2014-09-24. PMID:23979179. |
it is possible that in aerobically t subjects, a lower gip release is partly responsible for a lower postprandial incretin stimulated insulin secretion. |
2014-09-24 |
2023-08-12 |
human |
| Hidetada Ogata, Yusuke Seino, Norio Harada, Atsushi Iida, Kazuyo Suzuki, Takako Izumoto, Kota Ishikawa, Eita Uenishi, Nobuaki Ozaki, Yoshitaka Hayashi, Takashi Miki, Nobuya Inagaki, Shin Tsunekawa, Yoji Hamada, Susumu Seino, Yutaka Ois. KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state. The Journal of endocrinology. vol 222. issue 2. 2014-09-05. PMID:24891433. |
glucose-dependent insulinotropic polypeptide (gip), a gut hormone secreted from intestinal k-cells, potentiates insulin secretion. |
2014-09-05 |
2023-08-13 |
mouse |
| Daniela Nasteska, Norio Harada, Kazuyo Suzuki, Shunsuke Yamane, Akihiro Hamasaki, Erina Joo, Kanako Iwasaki, Kimitaka Shibue, Takanari Harada, Nobuya Inagak. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. vol 63. issue 7. 2014-09-03. PMID:24584548. |
chronic reduction of gip secretion alleviates obesity and insulin resistance under high-fat diet conditions. |
2014-09-03 |
2023-08-12 |
mouse |
| Daniela Nasteska, Norio Harada, Kazuyo Suzuki, Shunsuke Yamane, Akihiro Hamasaki, Erina Joo, Kanako Iwasaki, Kimitaka Shibue, Takanari Harada, Nobuya Inagak. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. vol 63. issue 7. 2014-09-03. PMID:24584548. |
when fed standard chow, gip(gfp/+) and gip(gfp/gfp) mice showed mild glucose intolerance with decreased insulin levels; bone volume was decreased in gip(gfp/gfp) mice and preserved in gip(gfp/+) mice. |
2014-09-03 |
2023-08-12 |
mouse |
| Daniela Nasteska, Norio Harada, Kazuyo Suzuki, Shunsuke Yamane, Akihiro Hamasaki, Erina Joo, Kanako Iwasaki, Kimitaka Shibue, Takanari Harada, Nobuya Inagak. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. vol 63. issue 7. 2014-09-03. PMID:24584548. |
under an hfd, glucose levels during an oral glucose tolerance test were similar in wild-type, gip(gfp/+), and gip(gfp/gfp) mice, while insulin secretion remained lower. |
2014-09-03 |
2023-08-12 |
mouse |
| Daniela Nasteska, Norio Harada, Kazuyo Suzuki, Shunsuke Yamane, Akihiro Hamasaki, Erina Joo, Kanako Iwasaki, Kimitaka Shibue, Takanari Harada, Nobuya Inagak. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. vol 63. issue 7. 2014-09-03. PMID:24584548. |
gip(gfp/+) and gip(gfp/gfp) mice showed reduced obesity and reduced insulin resistance, accompanied by higher fat oxidation and energy expenditure. |
2014-09-03 |
2023-08-12 |
mouse |
| Daniela Nasteska, Norio Harada, Kazuyo Suzuki, Shunsuke Yamane, Akihiro Hamasaki, Erina Joo, Kanako Iwasaki, Kimitaka Shibue, Takanari Harada, Nobuya Inagak. Chronic reduction of GIP secretion alleviates obesity and insulin resistance under high-fat diet conditions. Diabetes. vol 63. issue 7. 2014-09-03. PMID:24584548. |
gip-reduced mice demonstrate that partial reduction of gip does not extensively alter glucose tolerance, but it alleviates obesity and lessens the degree of insulin resistance under hfd conditions, suggesting a potential therapeutic value. |
2014-09-03 |
2023-08-12 |
mouse |
| R Charlotte Moffett, Nigel Irwin, Jacqueline M E Francis, Peter R Flat. Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. PloS one. vol 8. issue 11. 2014-09-02. PMID:24236022. |
circulating gip was unchanged during pregnancy, but non-fasting plasma glucose was significantly (p<0.01) decreased and insulin increased (p<0.05). |
2014-09-02 |
2023-08-12 |
rat |
| R Charlotte Moffett, Nigel Irwin, Jacqueline M E Francis, Peter R Flat. Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. PloS one. vol 8. issue 11. 2014-09-02. PMID:24236022. |
lactation was associated with elevated circulating gip concentrations (p<0.001) without change of glucose or insulin. |
2014-09-02 |
2023-08-12 |
rat |
| R Charlotte Moffett, Nigel Irwin, Jacqueline M E Francis, Peter R Flat. Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. PloS one. vol 8. issue 11. 2014-09-02. PMID:24236022. |
oral glucose resulted in a significantly (p<0.001) decreased glycaemic excursion despite similar glucose-induced gip and insulin concentrations in lactating rats. |
2014-09-02 |
2023-08-12 |
rat |
| R Charlotte Moffett, Nigel Irwin, Jacqueline M E Francis, Peter R Flat. Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation. PloS one. vol 8. issue 11. 2014-09-02. PMID:24236022. |
pregnant rats had a similar glycaemic excursion but exhibited significantly lowered (p<0.05) gip accompanied by elevated (p<0.001) insulin levels. |
2014-09-02 |
2023-08-12 |
rat |
| Anna Masajtis-Zagajewska, Ilona Kurnatowska, Małgorzata Wajdlich, Marta Jagodzińska, Michał Nowick. Influence of hemodialysis on incretin hormones and insulin secretion in diabetic and non-diabetic patients. International urology and nephrology. vol 45. issue 6. 2014-07-31. PMID:23670285. |
the aim of the study was to assess the effect of the commencement of chronic hemodialysis (hd) therapy on serum glp-1 and gip, and insulin sensitivity in diabetic and non-diabetic patients. |
2014-07-31 |
2023-08-12 |
Not clear |
| Sara Chowdhury, Songyan Wang, Bruce W Patterson, Dominic N Reeds, Burton M Wic. The combination of GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitus. Regulatory peptides. vol 187. 2014-07-16. PMID:24183983. |
we previously showed that xen increases the effect of glucose-dependent insulinotropic polypeptide (gip) on insulin release 1) in hyperglycemic mice via a cholinergic relay in the periphery independent from the central nervous system and 2) in humans with normal or impaired glucose tolerance, but not type 2 diabetes mellitus (t2dm). |
2014-07-16 |
2023-08-12 |
mouse |