| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L W Reneker, D W Silversides, K Patel, P A Overbee. TGF alpha can act as a chemoattractant to perioptic mesenchymal cells in developing mouse eyes. Development (Cambridge, England). vol 121. issue 6. 1995-08-10. PMID:7600984. |
upon binding to its receptor, the egf receptor (egfr), tgf alpha can exert diverse biological activities, such as induction of cell proliferation or differentiation. |
1995-08-10 |
2023-08-12 |
mouse |
| N Solic, J E Collins, A Richter, S J Holt, I Campbell, P Alexander, D E Davie. Two newly established cell lines derived from the same colonic adenocarcinoma exhibit differences in EGF-receptor ligand and adhesion molecule expression. International journal of cancer. vol 62. issue 1. 1995-08-10. PMID:7601566. |
only gp2d responded to exogenously added epidermal growth factor (egf), transforming growth factor-alpha (tgf alpha) or insulin with an increase in cell numbers, even though both cell lines possessed similar numbers of egf receptors. |
1995-08-10 |
2023-08-12 |
Not clear |
| N Solic, J E Collins, A Richter, S J Holt, I Campbell, P Alexander, D E Davie. Two newly established cell lines derived from the same colonic adenocarcinoma exhibit differences in EGF-receptor ligand and adhesion molecule expression. International journal of cancer. vol 62. issue 1. 1995-08-10. PMID:7601566. |
analysis of egf receptor ligand expression showed that gp5d cells expressed relatively more tgf alpha mrna than did gp2d; in contrast, amphiregulin mrna, which was abundant in gp2d, was virtually undetectable in gp5d. |
1995-08-10 |
2023-08-12 |
Not clear |
| K Krasagakis, C Garbe, C C Zouboulis, C E Orfano. Growth control of melanoma cells and melanocytes by cytokines. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. vol 139. 1995-08-03. PMID:7597288. |
melanoma cells are additionally stimulated by epidermal growth factor (egf)/transforming growth factor alpha (tgf-alpha) and nerve growth factor (ngf). |
1995-08-03 |
2023-08-12 |
human |
| D R Stover, M Becker, J Liebetanz, N B Lydo. Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha. The Journal of biological chemistry. vol 270. issue 26. 1995-08-01. PMID:7797556. |
upon egf treatment of mcf7 or three colorectal carcinoma cell lines (widr, dld-1, and ls174t), the egf-r coimmunoprecipitated with both p85 alpha and src. |
1995-08-01 |
2023-08-12 |
Not clear |
| M R Alison, R Chinery, R Poulsom, P Ashwood, J M Longcroft, N A Wrigh. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. The Journal of pathology. vol 175. issue 4. 1995-07-27. PMID:7790995. |
the trefoil peptides, rat spasmolytic polypeptide (rsp) and rat intestinal trefoil factor (ritf), along with epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) were the molecules studied. |
1995-07-27 |
2023-08-12 |
rat |
| M R Alison, R Chinery, R Poulsom, P Ashwood, J M Longcroft, N A Wrigh. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. The Journal of pathology. vol 175. issue 4. 1995-07-27. PMID:7790995. |
ulceration induced the very rapid expression of first rsp and then ritf mrna, whereas the mrnas encoding egf and tgf alpha increased at later times, with maxima recorded at 3 and 6 days, respectively. |
1995-07-27 |
2023-08-12 |
rat |
| M R Alison, R Chinery, R Poulsom, P Ashwood, J M Longcroft, N A Wrigh. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. The Journal of pathology. vol 175. issue 4. 1995-07-27. PMID:7790995. |
the pronounced, but temporally different patterns of mrna induction after ulceration suggest that the trefoil peptides may fulfil different and more immediate roles than the more 'traditional' healing proteins egf and tgf alpha. |
1995-07-27 |
2023-08-12 |
rat |
| S Sauma, F Huang, S Winawer, E Friedma. Colon goblet cells lose proliferative response to TGF alpha as they differentiate. International journal of cancer. vol 61. issue 6. 1995-07-25. PMID:7790121. |
two cell line models for colon goblet cells expressed 6- to 14-fold elevated levels of the egf receptor, 3- to 5-fold levels of tgf alpha and 11- to 15-fold levels of amphiregulin compared with 2 cell lines which model colon enterocytic differentiation, suggesting a role for the egf receptor and its ligands in goblet cell growth control. |
1995-07-25 |
2023-08-12 |
Not clear |
| T Imai, H Kurachi, K Adachi, H Adachi, Y Yoshimoto, H Homma, C Tadokoro, S Takeda, M Yamaguchi, M Sakat. Changes in epidermal growth factor receptor and the levels of its ligands during menstrual cycle in human endometrium. Biology of reproduction. vol 52. issue 4. 1995-07-20. PMID:7540053. |
we examined menstrual cycle-dependent changes in the expression of human endometrial epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), and epidermal growth factor receptor (egfr) and their mrna using immunoblot analysis, 125i-egf binding, and competitive reverse transcription and polymerase chain reaction (rt-pcr). |
1995-07-20 |
2023-08-12 |
human |
| M B Harvey, K J Leco, M Y Arcellana-Panlilio, X Zhang, D R Edwards, G A Schult. Roles of growth factors during peri-implantation development. Human reproduction (Oxford, England). vol 10. issue 3. 1995-07-20. PMID:7782459. |
genes for insulin-like growth factors (igfs), transforming growth factors (tgfs), fibroblast growth factor (fgf), platelet-derived growth factor (pdgf) and receptors for insulin, igf, pdgf, tgf alpha and epidermal growth factor (egf) are expressed by early embryos of several species including mouse, rat, cow and sheep. |
1995-07-20 |
2023-08-12 |
mouse |
| J Chen, T Liu, Q Cu. [Gene expression of growth factors, growth factor receptor and oncogenes in human lung cancer cell lines]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 24. issue 1. 1995-07-19. PMID:7781111. |
gene expression of growth factors including epidermal growth factor (egf), transforming growth factor alpha (tgf alpha), epidermal growth factor receptor (egfr), oncogenes such as c-myc, n-ras, c-erbb2 and tumor suppressor gene p53 were studied in 4 human lung cancer cell lines using northern blot technique. |
1995-07-19 |
2023-08-12 |
human |
| J Chen, T Liu, Q Cu. [Gene expression of growth factors, growth factor receptor and oncogenes in human lung cancer cell lines]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 24. issue 1. 1995-07-19. PMID:7781111. |
expression of egf and tgf alpha mrnas were found in all 4 cell lines and efgr mrna was seen in 3 out of 4 cell lines. |
1995-07-19 |
2023-08-12 |
human |
| J Chen, T Liu, Q Cu. [Gene expression of growth factors, growth factor receptor and oncogenes in human lung cancer cell lines]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 24. issue 1. 1995-07-19. PMID:7781111. |
another 2 cell lines had no c-myc but expressed large amounts of egf and tgf alpha mrna. |
1995-07-19 |
2023-08-12 |
human |
| L C Groenen, E C Nice, A W Burges. Structure-function relationships for the EGF/TGF-alpha family of mitogens. Growth factors (Chur, Switzerland). vol 11. issue 4. 1995-07-18. PMID:7779404. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) are ligands for the egf-receptor and act as mitogens for a variety of tissues. |
1995-07-18 |
2023-08-12 |
Not clear |
| E Spitzer, W Zschiesche, B Binas, R Grosse, B Erdman. EGF and TGF alpha modulate structural and functional differentiation of the mammary gland from pregnant mice in vitro: possible role of the arachidonic acid pathway. Journal of cellular biochemistry. vol 57. issue 3. 1995-07-06. PMID:7768984. |
egf and tgf alpha modulate structural and functional differentiation of the mammary gland from pregnant mice in vitro: possible role of the arachidonic acid pathway. |
1995-07-06 |
2023-08-12 |
mouse |
| E Spitzer, W Zschiesche, B Binas, R Grosse, B Erdman. EGF and TGF alpha modulate structural and functional differentiation of the mammary gland from pregnant mice in vitro: possible role of the arachidonic acid pathway. Journal of cellular biochemistry. vol 57. issue 3. 1995-07-06. PMID:7768984. |
tgf alpha showed qualitatively similar effects as egf but was generally a stronger agonist. |
1995-07-06 |
2023-08-12 |
mouse |
| E Spitzer, W Zschiesche, B Binas, R Grosse, B Erdman. EGF and TGF alpha modulate structural and functional differentiation of the mammary gland from pregnant mice in vitro: possible role of the arachidonic acid pathway. Journal of cellular biochemistry. vol 57. issue 3. 1995-07-06. PMID:7768984. |
it is suggested that egf and tgf alpha also play a role in mammary gland physiology during pregnancy by final developing and maintenance of the lobulo-alveolar structure in the mammary gland and prevention of premature onset of lactation, and that this is mediated through the pla2-arachidonic acid signalling cascade. |
1995-07-06 |
2023-08-12 |
mouse |
| C M Chia, R M Winston, A H Handysid. EGF, TGF-alpha and EGFR expression in human preimplantation embryos. Development (Cambridge, England). vol 121. issue 2. 1995-07-05. PMID:7768173. |
epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) through their common receptor, epidermal growth factor receptor (egfr) are known to enhance mitogenesis, development and implantation in several species. |
1995-07-05 |
2023-08-12 |
mouse |
| K Wojciechowski, L Trzeciak, S J Konturek, J Ostrowsk. Inhibition of acid secretory response and induction of ornithine decarboxylase and its mRNA by TGF alpha and EGF in isolated rat gastric glands. Regulatory peptides. vol 56. issue 1. 1995-07-05. PMID:7770629. |
inhibition of acid secretory response and induction of ornithine decarboxylase and its mrna by tgf alpha and egf in isolated rat gastric glands. |
1995-07-05 |
2023-08-12 |
rat |