| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Almahbobi, A Nagodavithane, A O Trounso. Effects of epidermal growth factor, transforming growth factor alpha and androstenedione on follicular growth and aromatization in culture. Human reproduction (Oxford, England). vol 10. issue 10. 1996-03-01. PMID:8567811. |
all treatments with egf, tgf alpha and androstenedione caused significant inhibitions in both follicular growth and oestradiol production, regardless of the dose used (1-20 ng/ml). |
1996-03-01 |
2023-08-12 |
mouse |
| G Almahbobi, A Nagodavithane, A O Trounso. Effects of epidermal growth factor, transforming growth factor alpha and androstenedione on follicular growth and aromatization in culture. Human reproduction (Oxford, England). vol 10. issue 10. 1996-03-01. PMID:8567811. |
these results suggest that egf, tgf alpha and/or androstenedione may play important roles in the modulation of gonadotrophin-controlled ovarian function. |
1996-03-01 |
2023-08-12 |
mouse |
| b' L Vinter-Jensen, C O Juhl, S S Poulsen, J C Djurhuus, E Z Dajani, E Nex\\xc3\\xb. Chronic administration of epidermal growth factor to pigs induces growth, especially of the urinary tract with accumulation of epithelial glycoconjugates. Laboratory investigation; a journal of technical methods and pathology. vol 73. issue 6. 1996-02-27. PMID:8558839.' |
epidermal growth factor (egf) receptor hyperstimulation induced by systemically administered egf or by the development of transgenic mice overexpressing transforming growth factor alpha (tgf alpha) or other egf-related ligands is known to induce various effects, such as acceleration of developmental processes like incisor eruption, inhibition of gastric acid secretion, morphologic changes in the pancreas resembling pancreatitis, and malignancies in mammary glands and the liver. |
1996-02-27 |
2023-08-12 |
mouse |
| T Machida, M Taga, H Minaguch. Effects of epidermal growth factor and transforming growth factor alpha on the mouse trophoblast outgrowth in vitro. European journal of endocrinology. vol 133. issue 6. 1996-02-22. PMID:8548061. |
in order to analyze the involvement of growth factors in the implantation mechanism, we examined the direct effects of epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) on trophoblast outgrowth of the mouse blastocyst in vitro. |
1996-02-22 |
2023-08-12 |
mouse |
| M A Narawane, V H Le. IGF-I and EGF receptors in the pigmented rabbit bulbar conjunctiva. Current eye research. vol 14. issue 10. 1996-02-20. PMID:8549156. |
the purpose of this study was to investigate whether receptors for insulin-like growth factors i and ii (igf-i and igf-ii), insulin, epidermal growth factor (egf), and transforming growth factor alpha (tgf alpha) are present on the apical surface of the pigmented rabbit bulbar conjunctiva. |
1996-02-20 |
2023-08-12 |
rabbit |
| M A Narawane, V H Le. IGF-I and EGF receptors in the pigmented rabbit bulbar conjunctiva. Current eye research. vol 14. issue 10. 1996-02-20. PMID:8549156. |
the ic50 value for displacement of bound 125i-egf was 0.37 +/- 0.03 nm by egf and 0.42 +/- 0.04 nm by tgf alpha. |
1996-02-20 |
2023-08-12 |
rabbit |
| M A Narawane, V H Le. IGF-I and EGF receptors in the pigmented rabbit bulbar conjunctiva. Current eye research. vol 14. issue 10. 1996-02-20. PMID:8549156. |
the igf-i receptor is also capable of binding igf-ii and insulin, whereas the egf receptor is also capable of binding tgf alpha. |
1996-02-20 |
2023-08-12 |
rabbit |
| K Adachi, H Kurachi, H Adachi, T Imai, M Sakata, H Homma, O Higashiguchi, T Yamamoto, A Miyak. Menstrual cycle specific expression of epidermal growth factor receptors in human fallopian tube epithelium. The Journal of endocrinology. vol 147. issue 3. 1996-02-13. PMID:8543926. |
next we examined whether egf receptor and its ligands (egf and transforming growth factor alpha) are directly induced by oestrogen. |
1996-02-13 |
2023-08-12 |
human |
| K E van Roozendaal, J G Klijn, B van Ooijen, C Claassen, A M Eggermont, S C Henzen-Logmans, J A Foeken. Differential regulation of breast tumor cell proliferation by stromal fibroblasts of various breast tissue sources. International journal of cancer. vol 65. issue 1. 1996-02-09. PMID:8543388. |
in addition, we show that igfs are only partly responsible for the observed proliferative effect of the c-sfms, while egf, tgf alpha and basic-fgf are shown not to be involved. |
1996-02-09 |
2023-08-12 |
Not clear |
| T Brzozowski, P C Konturek, S J Konturek, H Ernst, J Stachura, E G Hah. Gastric adaptation to injury by repeated doses of aspirin strengthens mucosal defence against subsequent exposure to various strong irritants in rats. Gut. vol 37. issue 6. 1996-02-06. PMID:8537043. |
the first dose of asa produced numerous gastric lesions and deep histological necrosis accompanied by a fall in the gastric blood flow, negligible expression of epidermal growth factor (egf) and transforming growth factor alpha (tgf alpha) or their receptors, and no evidence of mucosal proliferation. |
1996-02-06 |
2023-08-12 |
rat |
| T Brzozowski, P C Konturek, S J Konturek, H Ernst, J Stachura, E G Hah. Gastric adaptation to injury by repeated doses of aspirin strengthens mucosal defence against subsequent exposure to various strong irritants in rats. Gut. vol 37. issue 6. 1996-02-06. PMID:8537043. |
as adaptation to asa developed, however, the areas of gastric lesions were reduced by more than 80% and there was a noticeable decrease in deep necrosis, a partial restoration of gastric blood flow, an approximately four-fold increase in egf expression (but not in tgf alpha) and its receptors, and an appreciable increase in mucosal cell proliferation compared with vehicle treated rats. |
1996-02-06 |
2023-08-12 |
rat |
| S K Lee, P H Ster. EndothelinB receptor activation enhances parathyroid hormone-induced calcium signals in UMR-106 cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 10. issue 9. 1996-01-18. PMID:7502706. |
prostaglandin f1 alpha (pgf1 alpha) pretreatment also maximally potentiated pth responses, whereas alpha-thrombin, epidermal growth factor (egf), or prostaglandin e1 (pge1) did not affect the pth responses. |
1996-01-18 |
2023-08-12 |
mouse |
| K Guzman, S H Randell, P Netteshei. Epidermal growth factor regulates expression of the mucous phenotype of rat tracheal epithelial cells. Biochemical and biophysical research communications. vol 217. issue 2. 1996-01-18. PMID:7503716. |
following tissue injury and during inflammation the release of egf and its functional analogue tgf alpha have been observed and may be involved in the mucus hypersecretion characteristic of many airway diseases. |
1996-01-18 |
2023-08-12 |
rat |
| Z Chen, H S Nield, H Sun, A Barbier, T B Pate. Expression of type V adenylyl cyclase is required for epidermal growth factor-mediated stimulation of cAMP accumulation. The Journal of biological chemistry. vol 270. issue 46. 1996-01-17. PMID:7499211. |
as assessed by the ability of an anti-gs alpha antibody to obliterate the effect, stimulation of ac activity in ac v transfectants involved the participation of gs alpha, a finding consistent with previous data concerning egf effects on cardiac ac (nair, b. g., parikh, b., milligan, g., and patel, t. b. |
1996-01-17 |
2023-08-12 |
rat |
| E van der Zee, V Everts, K Hoeben, W Beertse. Cytokines modulate phagocytosis and intracellular digestion of collagen fibrils by fibroblasts in rabbit periosteal explants. Inverse effects on procollagenase production and collagen phagocytosis. Journal of cell science. vol 108 ( Pt 10). 1995-12-18. PMID:7593291. |
as the mechanisms involved in the regulation of the latter process are unknown, we investigated possible modulating effects of the cytokines epidermal growth factor (egf), platelet-derived growth factor (pdgf), interleukin-1 alpha (il-1 alpha) and transforming growth factor-beta (tgf-beta) on both collagen phagocytosis and the release of collagenase in an in vitro model employing periosteal tissue explants. |
1995-12-18 |
2023-08-12 |
rabbit |
| J Katz, H Weiss, B Goldman, H Kanety, B Stannard, D LeRoith, J Sheme. Cytokines and growth factors modulate cell growth and insulin-like growth factor binding protein secretion by the human salivary cell line (HSG). Journal of cellular physiology. vol 165. issue 2. 1995-12-05. PMID:7593199. |
similar igfbps were released by the cells following stimulation by egf and insulin as well as following incubation with the igf-i receptor antibody alpha ir3. |
1995-12-05 |
2023-08-12 |
human |
| H Xie, T Turner, M H Wang, R K Singh, G P Siegal, A Well. In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals. Clinical & experimental metastasis. vol 13. issue 6. 1995-11-30. PMID:7586799. |
prostate carcinomas often present an autocrine stimulatory loop in which the transformed cells both express the egf receptor (egfr) and produce activating ligands (tgf alpha and egf forms). |
1995-11-30 |
2023-08-12 |
human |
| T Fukay. [Human folliculogenesis and local regulation]. Nihon Sanka Fujinka Gakkai zasshi. vol 47. issue 8. 1995-11-29. PMID:7594882. |
in this study, we examined the localization of egf, tgf alpha and their receptor (egfr). |
1995-11-29 |
2023-08-12 |
human |
| T Maru. [Expression of oncogenes, growth factors and their receptors in follicular growth, regression and atresia: their roles in granulosa cell proliferation and differentiation]. Nihon Sanka Fujinka Gakkai zasshi. vol 47. issue 8. 1995-11-29. PMID:7594883. |
thus, in this study the role of several growth factors, such as thyroid hormone, insulin, insulin-like growth factor-i (igf-i), epidermal growth factor (egf), transforming growth factor-beta (tgf beta) and tumor necrosis factor-alpha (tnf alpha) were evaluated for their potential as endocrine, paracrine and/or autocrine regulators of granulosa cell proliferation and differentiation. |
1995-11-29 |
2023-08-12 |
Not clear |
| T Maru. [Expression of oncogenes, growth factors and their receptors in follicular growth, regression and atresia: their roles in granulosa cell proliferation and differentiation]. Nihon Sanka Fujinka Gakkai zasshi. vol 47. issue 8. 1995-11-29. PMID:7594883. |
on the other hand, thyroid hormone, insulin, igf-i and egf were found to be act as biological amplifiers (up-regulators) of fsh actions in granulosa cells, whereas tgf beta and tnf alpha were shown to act as down-regulators of fsh actions in granulosa cells. |
1995-11-29 |
2023-08-12 |
Not clear |