| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Török, R Urrutia, T Nakamura, M A McNive. Upregulation of molecular motor-encoding genes during hepatocyte growth factor- and epidermal growth factor-induced cell motility. Journal of cellular physiology. vol 167. issue 3. 1996-07-26. PMID:8655596. |
in contrast, egf upregulated the expression of myosin i alpha (2.4-fold), kinesin (1.5-fold), and dynein (1.5-fold) at 10 h. the expression of the beta-actin gene remained constant in hgf-treated cells, while egf induced a slight upregulation after 10 h of treatment. |
1996-07-26 |
2023-08-12 |
Not clear |
| M Akiyama, L T Smith, K A Holbroo. Growth factor and growth factor receptor localization in the hair follicle bulge and associated tissue in human fetus. The Journal of investigative dermatology. vol 106. issue 3. 1996-07-25. PMID:8648166. |
antibodies that recognize epidermal growth factor (egf), transforming growth factor-alpha (tgf-alpha), egf receptor, platelet-derived growth factor (pdgf) a and b chains, pdgf alpha and beta receptors, and the low-affinity nerve growth factor receptor (p75) were used to study the bulge and associated mesenchymal cells in this fetal period. |
1996-07-25 |
2023-08-12 |
human |
| Z Culig, A Hobisch, M V Cronauer, C Radmayr, A Hittmair, J Zhang, M Thurnher, G Bartsch, H Klocke. Regulation of prostatic growth and function by peptide growth factors. The Prostate. vol 28. issue 6. 1996-07-19. PMID:8650077. |
expression and biological effects of epidermal growth factor (egf), transforming growth factors (tgfs) alpha and beta, fibroblast growth factors (fgfs), and insulin-like growth factors (igfs) in the prostate have been extensively studied. |
1996-07-19 |
2023-08-12 |
rat |
| P Voigt, Y J Ma, D Gonzalez, W H Fahrenbach, W C Wetsel, K Berg-von der Emde, D F Hill, K G Taylor, M E Costa, N G Seidah, S R Ojed. Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons. Endocrinology. vol 137. issue 6. 1996-07-18. PMID:8641214. |
northern blot analysis showed that the lhrh-producing cell line gt1-7 contains the messenger rna (mrna) encoding the type 1 fibroblast growth factor receptor (fgfr-1) but not that encoding the epidermal growth factor (egf) receptors, which mediates the biological actions of both tgf alpha and egf. |
1996-07-18 |
2023-08-12 |
Not clear |
| P Voigt, Y J Ma, D Gonzalez, W H Fahrenbach, W C Wetsel, K Berg-von der Emde, D F Hill, K G Taylor, M E Costa, N G Seidah, S R Ojed. Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons. Endocrinology. vol 137. issue 6. 1996-07-18. PMID:8641214. |
exposure of gt1-7 cells to tgf alpha or egf failed to affect several parameters of cellular activity including lhrh release, lhrh and pc2 mrna levels, and cell proliferation. |
1996-07-18 |
2023-08-12 |
Not clear |
| D Stryjek-Kaminska, A Piiper, S Zeuze. Epidermal growth factor regulates adenylate cyclase activity via Gs and Gi1-2 proteins in pancreatic acinar membranes. The Biochemical journal. vol 316 ( Pt 1). 1996-07-18. PMID:8645237. |
anti-g alpha i1-2 antibody, but not anti-g alpha i3 antibody, abolished the inhibitory effect of egf on the forskolin- and vip-induced camp accumulation. |
1996-07-18 |
2023-08-12 |
rat |
| D Stryjek-Kaminska, A Piiper, S Zeuze. Epidermal growth factor regulates adenylate cyclase activity via Gs and Gi1-2 proteins in pancreatic acinar membranes. The Biochemical journal. vol 316 ( Pt 1). 1996-07-18. PMID:8645237. |
a peptide corresponding to the juxtamembrane region in the cytosolic domain of the rat egf receptor increased camp production in pancreatic acinar membranes in an anti-g alpha s antibody-sensitive fashion, whereas the egf receptor peptide did not mimic the inhibitory effect of the native egf receptor. |
1996-07-18 |
2023-08-12 |
rat |
| T Hirsch, S Eggstein, S Frank, E Farthmann, B U von Spech. Autocrine growth stimulation of SW403 colon carcinoma cell line is caused by transforming-growth-factor-alpha-mediated epidermal growth factor receptor activation. Journal of cancer research and clinical oncology. vol 122. issue 6. 1996-07-17. PMID:8642042. |
the cell line shows synthesis of egf receptors and tgf alpha but not egf, and exhibits constitutive phosphorylation of the 170-kda egfr. |
1996-07-17 |
2023-08-12 |
human |
| J M Peters, E C Tsark, L M Wile. Radiosensitive target in the mouse embryo chimera assay: implications that the target involves autocrine growth factor function. Radiation research. vol 145. issue 6. 1996-07-12. PMID:8643832. |
these embryos also express ligands that bind to and activate these receptors, including transforming growth factor alpha (tgf-alpha) and insulin-like growth factor ii (igf-ii), which bind to the egf receptor and igf-i receptor, respectively. |
1996-07-12 |
2023-08-12 |
mouse |
| E Malecka-Panas, S E Fligiel, N K Relan, S Dutta, A P Majumda. Azoxymethane enhances ligand-induced activation of EGF receptor tyrosine kinase in the colonic mucosa of rats. Carcinogenesis. vol 17. issue 2. 1996-06-24. PMID:8625444. |
recent observations suggest that transforming growth factor alpha (tgf-alpha), which binds to the epidermal growth factor (egf) receptor (egfr), may induce neoplastic growth of the colonic mucosa through an autocrine mechanism. |
1996-06-24 |
2023-08-12 |
rat |
| H Modjtahedi, C Dea. Monoclonal antibodies to the EGF receptor act as betacellulin antagonists. Biochemical and biophysical research communications. vol 221. issue 3. 1996-06-21. PMID:8630011. |
we have investigated whether monoclonal antibodies (mabs) to the egfr which act as egf, tgf alpha and hb-egf antagonists could also be effective as btc antagonists by blocking its binding to the egfr. |
1996-06-21 |
2023-08-12 |
human |
| M Naef, M Yokoyama, H Friess, M W Büchler, M Kor. Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma. International journal of cancer. vol 66. issue 3. 1996-06-18. PMID:8621250. |
heparin-binding epidermal growth factor (egf)-like growth factor (hb-egf) is a member of the egf family of polypeptide growth factors, which includes egf, transforming growth factor alpha(tgf-alpha), amphiregulin (ar) and betacellulin (btc). |
1996-06-18 |
2023-08-12 |
human |
| N Nakamura, Y Shidoji, H Moriwaki, Y Mut. Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha. Biochemical and biophysical research communications. vol 219. issue 1. 1996-06-13. PMID:8619789. |
either exogenous transforming growth factor-alpha (tgf alpha) or epidermal growth factor(egf) prevented the cells from apoptosis in the presence of 4,5-didehydro gga, but hepatocyte growth factor, insulin-like growth factor-ii, insulin or triiodothyronine was essentially inactive. |
1996-06-13 |
2023-08-12 |
human |
| N Nakamura, Y Shidoji, H Moriwaki, Y Mut. Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha. Biochemical and biophysical research communications. vol 219. issue 1. 1996-06-13. PMID:8619789. |
taken together, the present study strongly suggests that 4,5-didehydro gga induced apoptosis in huh-7 cells through the destruction of autocrine loop consisting of tgf alpha and egf receptor, due to the down regulation of tgf alpha gene expression. |
1996-06-13 |
2023-08-12 |
human |
| P Briand, K V Nielsen, M W Madsen, O W Peterse. Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal. Cancer research. vol 56. issue 9. 1996-06-12. PMID:8616848. |
we hypothesize that during premalignant hyperplasia, a population of egf/transforming growth factor alpha autonomous epithelial cells in situ may develop as a consequence of local transforming growth factor alpha deprivation, a condition reflected in the culture model as autonomy after egf withdrawal. |
1996-06-12 |
2023-08-12 |
mouse |
| D M Ignar-Trowbridge, M Pimentel, M G Parker, J A McLachlan, K S Korac. Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol. Endocrinology. vol 137. issue 5. 1996-06-05. PMID:8612509. |
we have assessed the effects of epidermal growth factor (egf), transforming growth factor-alpha (tgf alpha), and insulin-like growth factor i (igf-i) on transcription from consensus estrogen response elements (ere) in estrogen receptor (er)-positive bg-1 human ovarian adenocarcinoma calls. |
1996-06-05 |
2023-08-12 |
human |
| D M Ignar-Trowbridge, M Pimentel, M G Parker, J A McLachlan, K S Korac. Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol. Endocrinology. vol 137. issue 5. 1996-06-05. PMID:8612509. |
combinations of e2 with tgf alpha or igf-i induced synergistic activation of transcription from an ere, whereas as additive response was observed with combinations of igf-i and tgf alpha of egf. |
1996-06-05 |
2023-08-12 |
human |
| M Romano, C A Lesch, K S Meise, M Veljaca, B Sanchez, E R Kraus, C R Boland, A Guglietta, R J Coffe. Increased gastroduodenal concentrations of transforming growth factor alpha in adaptation to aspirin in monkeys and rats. Gastroenterology. vol 110. issue 5. 1996-06-05. PMID:8613050. |
transforming growth factor alpha (tgf-alpha) and epidermal growth factor (egf) prevent drug-induced gastric injury. |
1996-06-05 |
2023-08-12 |
rat |
| J K Mellon, S Cook, P Chambers, D E Nea. Transforming growth factor alpha and epidermal growth factor levels in bladder cancer and their relationship to epidermal growth factor receptor. British journal of cancer. vol 73. issue 5. 1996-05-17. PMID:8605103. |
we have examined levels of epidermal growth factor (egf) and transforming growth factor alpha (tgf-alpha) in neoplastic and non-neoplastic bladder tissue using a standard radioimmunoassay technique. |
1996-05-17 |
2023-08-12 |
Not clear |
| G D Block, J Locker, W C Bowen, B E Petersen, S Katyal, S C Strom, T Riley, T A Howard, G K Michalopoulo. Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. The Journal of cell biology. vol 132. issue 6. 1996-05-09. PMID:8601590. |
population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by hgf/sf, egf and tgf alpha in a chemically defined (hgm) medium. |
1996-05-09 |
2023-08-12 |
Not clear |