| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Cristina Hern\\xc3\\xa1ndez, Olga Sim\\xc3\\xb3-Servat, Rafael Sim\\xc3\\xb. Somatostatin and diabetic retinopathy: current concepts and new therapeutic perspectives. Endocrine. vol 46. issue 2. 2015-01-19. PMID:24627166.' |
in conclusion, sst is a natural neuroprotective and antiangiogenic factor synthesized by the retina which is downregulated in the diabetic eye and, therefore, its replacement seems a rational approach for treating dr. |
2015-01-19 |
2023-08-12 |
human |
| Pavan Kumar Mishra, Abhijit Sinha, Kaveti Ravi Teja, Nitin Bhojwani, Sagar Sahu, Awanish Kuma. A computational modeling for the detection of diabetic retinopathy severity. Bioinformation. vol 10. issue 9. 2014-10-29. PMID:25352722. |
through advanced image analysis techniques are used for abnormalities detection in retina that define and correlate the severity of dr. a thorough study is done in this area in recent past years and on the basis of these studies we have developed a computer based prediction model that is used to determine the severity of dr. to identify severity dr, we have analyzed the human eye image. |
2014-10-29 |
2023-08-13 |
human |
| Mohammad Shamsul Ola, Abdullah S Alhomid. Neurodegeneration in diabetic retina and its potential drug targets. Current neuropharmacology. vol 12. issue 4. 2014-10-24. PMID:25342945. |
dr is widely recognized as a neurodegenerative disease as evidenced from early changes at cellular and molecular levels in the neuronal component of the diabetic retina, which is further supported by various retinal functional tests indicating functional deficits in the retina soon after diabetes progression. |
2014-10-24 |
2023-08-13 |
Not clear |
| M Usman Akram, Shehzad Khalid, Anam Tariq, Shoab A Khan, Farooque Aza. Detection and classification of retinal lesions for grading of diabetic retinopathy. Computers in biology and medicine. vol 45. 2014-09-15. PMID:24480176. |
diabetic retinopathy (dr) is an eye abnormality in which the human retina is affected due to an increasing amount of insulin in blood. |
2014-09-15 |
2023-08-12 |
human |
| M Usman Akram, Shehzad Khalid, Anam Tariq, Shoab A Khan, Farooque Aza. Detection and classification of retinal lesions for grading of diabetic retinopathy. Computers in biology and medicine. vol 45. 2014-09-15. PMID:24480176. |
the early signs of dr which appear on the surface of the retina are microaneurysms, haemorrhages, and exudates. |
2014-09-15 |
2023-08-12 |
human |
| Rafael Simó, Cristina Hernánde. Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives. Trends in endocrinology and metabolism: TEM. vol 25. issue 1. 2014-09-02. PMID:24183659. |
diabetic retinopathy (dr), one of the leading causes of preventable blindness, has been considered a microcirculatory disease of the retina. |
2014-09-02 |
2023-08-12 |
Not clear |
| Rita Mclauchla. Patient support to reduce risk diabetic retinopathy. Nursing times. vol 110. issue 25. 2014-08-20. PMID:25087401. |
diabetic retinopathy (dr) is the most common cause of blindness in the western world resulting in damage to the blood vessels of the retina. |
2014-08-20 |
2023-08-13 |
Not clear |
| Yousef H Aldebasi, Salah M Aly, Arshad H Rahman. Therapeutic implications of curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathways. International journal of physiology, pathophysiology and pharmacology. vol 5. issue 4. 2014-06-24. PMID:24379904. |
diabetic retinopathy (dr) is one of the most common complications of diabetes mellitus that affects the blood vessels of the retina, leading to blindness. |
2014-06-24 |
2023-08-12 |
Not clear |
| Donald L Blanchar. Emily Dickinson's ophthalmic consultation with Henry Willard Williams, MD. Archives of ophthalmology (Chicago, Ill. : 1960). vol 130. issue 12. 2014-06-12. PMID:23229703. |
rather than attempt a definitive conclusion, this article will offer an additional possibility that dr williams likely considered (ie, hysterical hyperaesthesia of the retina). |
2014-06-12 |
2023-08-12 |
Not clear |
| b' Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Somatostatin replacement: a new strategy for treating diabetic retinopathy. Current medicinal chemistry. vol 20. issue 26. 2014-05-22. PMID:23745546.' |
diabetic retinopathy (dr) has been classically considered to be a microcirculatory disease of the retina. |
2014-05-22 |
2023-08-12 |
rat |
| b' Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Somatostatin replacement: a new strategy for treating diabetic retinopathy. Current medicinal chemistry. vol 20. issue 26. 2014-05-22. PMID:23745546.' |
diabetic retinopathy (dr) has been classically considered to be a microcirculatory disease of the retina. |
2014-05-22 |
2023-08-12 |
rat |
| Moe H Aung, Han Na Park, Moon K Han, Tracy S Obertone, Jane Abey, Fazila Aseem, Peter M Thule, P Michael Iuvone, Machelle T Pardu. Dopamine deficiency contributes to early visual dysfunction in a rodent model of type 1 diabetes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 3. 2014-03-13. PMID:24431431. |
because the retina is rich in da and has a well known diabetes-induced pathology (diabetic retinopathy or dr), this study was designed to examine the role of retinal da deficiency in early visual defects in dr. |
2014-03-13 |
2023-08-12 |
mouse |
| Laura Campello, Julián Esteve-Rudd, Nicolás Cuenca, José Martín-Niet. The ubiquitin-proteasome system in retinal health and disease. Molecular neurobiology. vol 47. issue 2. 2014-02-13. PMID:23339020. |
additionally, the relationship between ups dysfunction and human neurodegenerative disorders affecting the retina, including alzheimer's, parkinson's, and huntington's diseases, are dealt with, together with numerous instances of retina-specific illnesses with ups involvement, such as retinitis pigmentosa, macular degenerations, glaucoma, diabetic retinopathy (dr), and aging-related impairments. |
2014-02-13 |
2023-08-12 |
human |
| Xiaochen Liu, Bin Zhang, Jeffrey D McBride, Kevin Zhou, Kyungwon Lee, Yueping Zhou, Zuguo Liu, Jian-xing M. Antiangiogenic and antineuroinflammatory effects of kallistatin through interactions with the canonical Wnt pathway. Diabetes. vol 62. issue 12. 2014-01-17. PMID:23884893. |
overactivation of the wnt pathway is known to play pathogenic roles in dr. to investigate the role of kallistatin in dr and in wnt pathway activation, we generated kallistatin transgenic (kallistatin-tg) mice overexpressing kallistatin in multiple tissues including the retina. |
2014-01-17 |
2023-08-12 |
mouse |
| Saeed Yadranji Aghdam, Nader Sheiban. The ubiquitin-proteasome system and microvascular complications of diabetes. Journal of ophthalmic & vision research. vol 8. issue 3. 2013-12-18. PMID:24349668. |
high blood glucose or hyperglycemia caused by diabetes disrupts normal vascular function in several target organs including the retina and kidney resulting in the development of diabetic retinopathy (dr) and diabetic nephropathy (dn). |
2013-12-18 |
2023-08-12 |
Not clear |
| Mehreen Adhi, Erika Brewer, Nadia K Waheed, Jay S Duke. Analysis of morphological features and vascular layers of choroid in diabetic retinopathy using spectral-domain optical coherence tomography. JAMA ophthalmology. vol 131. issue 10. 2013-12-10. PMID:23907153. |
diabetic retinopathy (dr) is characterized by microaneurysms, capillary nonperfusion, and ischemia within the retina, ultimately leading to neovascularization and/or macular edema. |
2013-12-10 |
2023-08-12 |
Not clear |
| P Kolá. [Patophysiology of diabetic retinopathy]. Vnitrni lekarstvi. vol 59. issue 3. 2013-11-12. PMID:23713183. |
diabetic retinopathy (dr) is the affection of the retina in patients with diabetes mellitus (dm). |
2013-11-12 |
2023-08-12 |
Not clear |
| Hirotaka Yokouchi, Koki Eto, Wataru Nishimura, Norio Takeda, Yasushi Kaburagi, Shuichi Yamamoto, Kazuki Yasud. Angiopoietin-like protein 4 (ANGPTL4) is induced by high glucose in retinal pigment epithelial cells and exhibits potent angiogenic activity on retinal endothelial cells. Acta ophthalmologica. vol 91. issue 4. 2013-10-22. PMID:23387337. |
it is widely accepted that the progression of dr is mainly due to a local imbalance of pro- versus anti-angiogenic factors in the retina. |
2013-10-22 |
2023-08-12 |
Not clear |
| b' Angela M Valverde, Soledad Miranda, Marta Garc\\xc3\\xada-Ram\\xc3\\xadrez, \\xc3\\x81gueda Gonz\\xc3\\xa1lez-Rodriguez, Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Proapoptotic and survival signaling in the neuroretina at early stages of diabetic retinopathy. Molecular vision. vol 19. 2013-09-06. PMID:23335850.' |
diabetic retinopathy (dr) has been classically considered a microcirculatory disease of the retina. |
2013-09-06 |
2023-08-12 |
Not clear |
| M Shamsul Ola, Mohd Imtiaz Nawaz, Ahmed Abu El-Asrar, Marwan Abouammoh, Abdullah S Alhomid. Reduced levels of brain derived neurotrophic factor (BDNF) in the serum of diabetic retinopathy patients and in the retina of diabetic rats. Cellular and molecular neurobiology. vol 33. issue 3. 2013-09-04. PMID:23271640. |
in this study, we investigated the level of bdnf in the serum of patients with dr and also in the serum and retina of streptozotocin-induced diabetic rats. |
2013-09-04 |
2023-08-12 |
rat |