| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pei Zhuang, Chithra K Muraleedharan, Shunbin X. Intraocular Delivery of miR-146 Inhibits Diabetes-Induced Retinal Functional Defects in Diabetic Rat Model. Investigative ophthalmology & visual science. vol 58. issue 3. 2017-06-26. PMID:28297724. |
we hypothesized that mir-146 plays an important role in diabetic retinopathy (dr) by inhibiting diabetes-induced inflammatory response in the retina. |
2017-06-26 |
2023-08-13 |
rat |
| Elisabeth Anne Obara, Jens Hannibal, Steffen Heegaard, Jan Fahrenkru. Loss of Melanopsin-Expressing Retinal Ganglion Cells in Patients With Diabetic Retinopathy. Investigative ophthalmology & visual science. vol 58. issue 4. 2017-06-26. PMID:28399269. |
the aim of this study was to assess the impact of dr on the expression of mrgcs in the human retina. |
2017-06-26 |
2023-08-13 |
human |
| Rosario Amato, Martina Biagioni, Maurizio Cammalleri, Massimo Dal Monte, Giovanni Casin. VEGF as a Survival Factor in Ex Vivo Models of Early Diabetic Retinopathy. Investigative ophthalmology & visual science. vol 57. issue 7. 2017-06-19. PMID:27286364. |
we tested the hypothesis that vegf is released and acts as a survival factor in the retina in early dr. |
2017-06-19 |
2023-08-13 |
Not clear |
| Raul Carpi-Santos, Marcos José Ferreira, Annibal Duarte Pereira Netto, Elizabeth Giestal-de-Araujo, Ana Lucia Marques Ventura, Marcelo Cossenza, Karin C Calaz. Early changes in system [Formula: see text] and glutathione in the retina of diabetic rats. Experimental eye research. vol 146. 2017-06-15. PMID:26706282. |
diabetic retinopathy (dr), the main cause of blindness among diabetic patients, affects both neuronal and vascular cells of the retina. |
2017-06-15 |
2023-08-13 |
rat |
| b' Bur\\xc3\\xa7in Yavuz, Sibel Bozda\\xc4\\x9f Pehlivan, Burcu S\\xc3\\xbcmer Bolu, Rana Nomak Sanyal, \\xc4\\xb0mran Vural, Nur\\xc5\\x9fen \\xc3\\x9cnl\\xc3\\xb. Dexamethasone - PAMAM dendrimer conjugates for retinal delivery: preparation, characterization and in vivo evaluation. The Journal of pharmacy and pharmacology. vol 68. issue 8. 2017-06-12. PMID:27283886.' |
ocular diseases affecting retina, such as diabetic retinopathy (dr), age-related macular degeneration (amd) and glaucoma are the major causes of blindness, and their treatment is still a challenge due to the special structure of the eye. |
2017-06-12 |
2023-08-13 |
Not clear |
| Gianni Virgili, Francesca Menchini, Giovanni Casazza, Ruth Hogg, Radha R Das, Xue Wang, Manuele Micheless. Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy. The Cochrane database of systematic reviews. vol 1. 2017-05-16. PMID:25564068. |
diabetic macular oedema (dmo) is a thickening of the central retina, or the macula, and is associated with long-term visual loss in people with diabetic retinopathy (dr). |
2017-05-16 |
2023-08-13 |
Not clear |
| Malihe Javidi, Hamid-Reza Pourreza, Ahad Harat. Vessel segmentation and microaneurysm detection using discriminative dictionary learning and sparse representation. Computer methods and programs in biomedicine. vol 139. 2017-04-11. PMID:28187898. |
microaneurysm (ma) is the earliest sign of dr that appears as a small red dot on the surface of the retina. |
2017-04-11 |
2023-08-13 |
Not clear |
| Ahmed ElTanboly, Marwa Ismail, Ahmed Shalaby, Andy Switala, Ayman El-Baz, Shlomit Schaal, Georgy Gimel'farb, Magdi El-Aza. A computer-aided diagnostic system for detecting diabetic retinopathy in optical coherence tomography images. Medical physics. vol 44. issue 3. 2017-03-28. PMID:28035657. |
detection (diagnosis) of diabetic retinopathy (dr) in optical coherence tomography (oct) images for patients with type 2 diabetes, but almost clinically normal retina appearances. |
2017-03-28 |
2023-08-13 |
Not clear |
| Thing-Fong Tzeng, Shorong-Shii Liou, Yu-Cheng Tzeng, I-Min Li. Zerumbone, a Phytochemical of Subtropical Ginger, Protects against Hyperglycemia-Induced Retinal Damage in Experimental Diabetic Rats. Nutrients. vol 8. issue 8. 2017-03-17. PMID:27463726. |
diabetic retinopathy (dr), the most ordinary and specific microvascular complication of diabetes, is a disease of the retina. |
2017-03-17 |
2023-08-13 |
rat |
| Heping Xu, Mei Che. Targeting the complement system for the management of retinal inflammatory and degenerative diseases. European journal of pharmacology. vol 787. 2017-03-06. PMID:26948311. |
the retina, an immune privileged tissue, has specialized immune defense mechanisms against noxious insults that may exist in diseases such as age-related macular degeneration (amd), diabetic retinopathy (dr), uveoretinitis and glaucoma. |
2017-03-06 |
2023-08-13 |
Not clear |
| Joaquín Valdés, Laura Trachsel-Moncho, Ayse Sahaboglu, Dragana Trifunović, María Miranda, Marius Ueffing, François Paquet-Durand, Oliver Schmachtenber. Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies. ALTEX. vol 33. issue 4. 2017-01-17. PMID:27159027. |
here, we introduce an alternative in vitro model system for dr, based on serum-free, organotypic rodent retinal explant cultures, which allow physiological and pharmacological manipulation of the retina for up to two weeks under tightly controlled conditions. |
2017-01-17 |
2023-08-13 |
Not clear |
| Sofia M Calado, Francisco Diaz-Corrales, Gabriela A Silv. pEPito-driven PEDF Expression Ameliorates Diabetic Retinopathy Hallmarks. Human gene therapy methods. vol 27. issue 2. 2016-12-30. PMID:26942449. |
laser photocoagulation and vitrectomy are the most efficient treatments for dr, but display severe side effects such as the destruction of the healthy retina. |
2016-12-30 |
2023-08-13 |
mouse |
| Yuan-Jie Liu, Zhi-Yun Lian, Geng Liu, Hong-Ying Zhou, Hui-Jun Yan. RNA sequencing reveals retinal transcriptome changes in STZ-induced diabetic rats. Molecular medicine reports. vol 13. issue 3. 2016-12-19. PMID:26781437. |
diabetes alters several transcripts in the retina, and rna‑seq provides novel insights into the molecular mechanisms underlying dr. |
2016-12-19 |
2023-08-13 |
rat |
| K Szabadfi, D Reglodi, A Szabo, B Szalontai, A Valasek, Gy Setalo, P Kiss, A Tamas, M Wilhelm, R Gabrie. Pituitary Adenylate Cyclase Activating Polypeptide, A Potential Therapeutic Agent for Diabetic Retinopathy in Rats: Focus on the Vertical Information Processing Pathway. Neurotoxicity research. vol 29. issue 3. 2016-12-13. PMID:26739825. |
diabetic retinopathy (dr), the most common complication of diabetes, affects the microvasculature and neuronal architecture of the retina. |
2016-12-13 |
2023-08-13 |
rat |
| Cristina Hernández, Massimo Dal Monte, Rafael Simó, Giovanni Casin. Neuroprotection as a Therapeutic Target for Diabetic Retinopathy. Journal of diabetes research. vol 2016. 2016-12-13. PMID:27123463. |
diabetic retinopathy (dr) is a multifactorial progressive disease of the retina and a leading cause of vision loss. |
2016-12-13 |
2023-08-13 |
Not clear |
| Seong-Jae Kim, Woong-Sun Yoo, Meeyoung Choi, Inyoung Chung, Ji-Myong Yoo, Wan-Sung Cho. Increased O-GlcNAcylation of NF-κB Enhances Retinal Ganglion Cell Death in Streptozotocin-induced Diabetic Retinopathy. Current eye research. vol 41. issue 2. 2016-10-26. PMID:25835259. |
we examined whether hyperglycemia increases o-glcnacylation in the diabetic retina and whether elevated o-glcnacylation of nuclear factor (nf)-κb increases apoptosis of retinal ganglion cells (rgcs) in diabetic retinopathy (dr). |
2016-10-26 |
2023-08-13 |
Not clear |
| Wen-Qin Xu, Yu-Sheng Wan. The role of Toll-like receptors in retinal ischemic diseases. International journal of ophthalmology. vol 9. issue 9. 2016-09-27. PMID:27672603. |
growing evidence has demonstrated that the expression of tlrs in the retina is regulated during retinal ischemic diseases, including ischemia-reperfusion injury, glaucoma, diabetic retinopathy (dr) and retinopathy of prematurity (rop). |
2016-09-27 |
2023-08-13 |
Not clear |
| Michelle W Sahli, Julie A Mares, Kristin J Meyers, Ronald Klein, William E Brady, Barbara E K Klein, Heather M Ochs-Balcom, Richard P Donahue, Amy E Mille. Dietary Intake of Lutein and Diabetic Retinopathy in the Atherosclerosis Risk in Communities Study (ARIC). Ophthalmic epidemiology. vol 23. issue 2. 2016-09-16. PMID:26949989. |
we tested the hypothesis that dietary intake of lutein is inversely associated with prevalence of diabetic retinopathy (dr) due to its antioxidant and anti-inflammatory properties and location within the retina. |
2016-09-16 |
2023-08-13 |
Not clear |
| I N Figueiredo, S Kumar, C M Oliveira, J D Ramos, B Engquis. Automated lesion detectors in retinal fundus images. Computers in biology and medicine. vol 66. 2016-09-14. PMID:26378502. |
diabetic retinopathy (dr) is a sight-threatening condition occurring in persons with diabetes, which causes progressive damage to the retina. |
2016-09-14 |
2023-08-13 |
Not clear |
| I N Figueiredo, S Kumar, C M Oliveira, J D Ramos, B Engquis. Automated lesion detectors in retinal fundus images. Computers in biology and medicine. vol 66. 2016-09-14. PMID:26378502. |
the early signs of dr which appear on the surface of the retina are the dark lesions such as microaneurysms (mas) and hemorrhages (hems), and bright lesions (bls) such as exudates. |
2016-09-14 |
2023-08-13 |
Not clear |