| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Shamsul Ola, Mohd Imtiaz Nawaz, Ahmed Abu El-Asrar, Marwan Abouammoh, Abdullah S Alhomid. Reduced levels of brain derived neurotrophic factor (BDNF) in the serum of diabetic retinopathy patients and in the retina of diabetic rats. Cellular and molecular neurobiology. vol 33. issue 3. 2013-09-04. PMID:23271640. |
our results indicate that reduced levels of bdnf in diabetes may cause apoptosis and neurodegeneration early in diabetic retina, which may lead to neuro-vascular damage later in dr. |
2013-09-04 |
2023-08-12 |
rat |
| Piyush Rameshchandra Ramavat, Manish Rameshchandra Ramavat, Balaji Wasudeo Ghugare, Rohini G Vaishnav, Manjiri Uttam Josh. Prevalence of Diabetic Retinopathy in Western Indian Type 2 Diabetic Population: A Hospital - based Cross - Sectional Study. Journal of clinical and diagnostic research : JCDR. vol 7. issue 7. 2013-09-02. PMID:23998071. |
diabetic retinopathy (dr) can be defined as a damage which is caused to microvasculature in the retina by prolonged hyperglycaemia. |
2013-09-02 |
2023-08-12 |
Not clear |
| Ezequiel M Salido, Melina Bordone, Andrea De Laurentiis, Mónica Chianelli, María Inés Keller Sarmiento, Damián Dorfman, Ruth E Rosenstei. Therapeutic efficacy of melatonin in reducing retinal damage in an experimental model of early type 2 diabetes in rats. Journal of pineal research. vol 54. issue 2. 2013-08-26. PMID:22946773. |
these results indicate that melatonin protected the retina from the alterations observed in an experimental model of dr associated with type 2 diabetes. |
2013-08-26 |
2023-08-12 |
human |
| Dragana Matanovic, Srdjan Popovic, Biljana Parapid, Ivana Petronic, Dragana Cirovic, Dejan Nikoli. Influence of the metabolic control on latency values of visual evoked potentials (VEP) in patients with diabetes mellitus type 1. Archives italiennes de biologie. vol 150. issue 4. 2013-08-06. PMID:23479458. |
if changes in the retina could be detected before dr is noticed using this noninvasive diagnostic procedure and include patients in a strict glycoregulation, we could be in the position to prevent serious complications that may cause blindness. |
2013-08-06 |
2023-08-12 |
Not clear |
| Carla Agurto, Honggang Yu, Victor Murray, Marios S Pattichis, Simon Barriga, Wendall Bauman, Peter Soli. Detection of neovascularization in the optic disc using an AM-FM representation, granulometry, and vessel segmentation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2012. 2013-08-01. PMID:23367037. |
neovascularization, defined as abnormal formation of blood vessels in the retina, is a sight-threatening condition indicative of late-stage diabetic retinopathy (dr). |
2013-08-01 |
2023-08-12 |
Not clear |
| Rania Azmy, Ashraf Dawood, Ayman Kilany, Yasser El-Ghobashy, Amin Faisal Ellakwa, May El-Dal. Association analysis of genetic variations of eNOS and α2β1 integrin genes with type 2 diabetic retinopathy. The application of clinical genetics. vol 5. 2013-06-19. PMID:23776381. |
diabetic retinopathy (dr) is classically defined as a microvasculopathy that primarily affects the small blood vessels of the inner retina as a complication of diabetes mellitus. |
2013-06-19 |
2023-08-12 |
Not clear |
| Na-Young Lee, Young-Sook Kan. The effects of bisphosphonates on taurine transport in retinal capillary endothelial cells under high glucose conditions. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392871. |
elevated glucose and vascular endothelial growth factor (vegf) in retina can trigger many of the retinal vascular changes caused by diabetes and dr. |
2013-06-12 |
2023-08-12 |
Not clear |
| Na-Young Lee, Young-Sook Kan. The effects of bisphosphonates on taurine transport in retinal capillary endothelial cells under high glucose conditions. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392871. |
therefore, we suggest that bisphosphonates could have the beneficial effects on dr by regulation of taurine contents in retina. |
2013-06-12 |
2023-08-12 |
Not clear |
| P Sapieha, J Chen, A Stahl, M R Seaward, T L Favazza, A M Juan, C J Hatton, J-S Joyal, N M Krah, R J Dennison, J Tang, T S Kern, J D Akula, L E H Smit. Omega-3 polyunsaturated fatty acids preserve retinal function in type 2 diabetic mice. Nutrition & diabetes. vol 2. 2013-03-04. PMID:23448719. |
diabetic retinopathy (dr) is associated with hyperglycemia-driven microvascular pathology and neuronal compromise in the retina. |
2013-03-04 |
2023-08-12 |
mouse |
| Yu Xiang George Kong, Nicole van Bergen, Bang V Bui, Vicki Chrysostomou, Algis J Vingrys, Ian A Trounce, Jonathan G Crowsto. Impact of aging and diet restriction on retinal function during and after acute intraocular pressure injury. Neurobiology of aging. vol 33. issue 6. 2013-01-24. PMID:22217415. |
taken together, this study provides in vivo evidence that dr improves functional recovery of the retina following injury and points to the potential benefits of therapies that target mitochondria for the protection of the aging retina and optic nerve against injury. |
2013-01-24 |
2023-08-12 |
mouse |
| Letícia A Brondani, Bianca M de Souza, Guilherme C K Duarte, Lúcia M Kliemann, Jorge F Esteves, Alexandre S Marcon, Jorge L Gross, Luís H Canani, Daisy Crispi. The UCP1 -3826A/G polymorphism is associated with diabetic retinopathy and increased UCP1 and MnSOD2 gene expression in human retina. Investigative ophthalmology & visual science. vol 53. issue 12. 2013-01-15. PMID:23033381. |
therefore, deleterious polymorphisms in the ucp1 gene are candidate risk factors for dr. we investigated the relationships between the ucp1 -3826a/g polymorphism and risk of dr and ucp1 gene expression in human retina. |
2013-01-15 |
2023-08-12 |
human |
| Rafael Simó, Cristina Hernánde. Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications. The British journal of ophthalmology. vol 96. issue 10. 2013-01-08. PMID:22887976. |
dr has been classically considered to be a microcirculatory disease of the retina. |
2013-01-08 |
2023-08-12 |
Not clear |
| Hui-Zhuo Xu, Zhiming Song, Shuhua Fu, Meili Zhu, Yun-Zheng L. RPE barrier breakdown in diabetic retinopathy: seeing is believing. Journal of ocular biology, diseases, and informatics. vol 4. issue 1-2. 2013-01-01. PMID:23275801. |
as the blood content leaked through the rpe barrier causes excessive water influx to the retina, the breakdown of the rpe barrier is likely to play a causative role in the development of some forms of diabetic macular edema, a major cause of vision loss in dr. |
2013-01-01 |
2023-08-12 |
Not clear |
| Min Ke, Xin-Qian Hu, Jingping Ouyang, Bo Dai, Yancheng X. The effect of astragalin on the VEGF production of cultured Müller cells under high glucose conditions. Bio-medical materials and engineering. vol 22. issue 1-3. 2012-11-07. PMID:22766709. |
to evaluate the effect of astragalin in preventing and treating dr and determine astragalin's mechanism of action, müller cells were collected from rat retina, cultured in vitro and identified using immunocytochemistry. |
2012-11-07 |
2023-08-12 |
rat |
| b' Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Neuroprotection in diabetic retinopathy. Current diabetes reports. vol 12. issue 4. 2012-10-22. PMID:22581259.' |
diabetic retinopathy (dr) has been considered to be a microcirculatory disease of the retina. |
2012-10-22 |
2023-08-12 |
Not clear |
| B Kumar, S K Gupta, R Saxena, S Srivastav. Current trends in the pharmacotherapy of diabetic retinopathy. Journal of postgraduate medicine. vol 58. issue 2. 2012-09-28. PMID:22718058. |
diabetic retinopathy (dr) is one of the most debilitating disorders of microvasculature of the retina and one of the leading causes of vision loss among the working class worldwide. |
2012-09-28 |
2023-08-12 |
Not clear |
| Cemal Köse, Uğur Sevik, Cevat Ikibaş, Hidayet Erdö. Simple methods for segmentation and measurement of diabetic retinopathy lesions in retinal fundus images. Computer methods and programs in biomedicine. vol 107. issue 2. 2012-09-27. PMID:21757250. |
diabetic retinopathy (dr) is one of the most important complications of diabetes mellitus, which causes serious damages in the retina, consequently visual loss and sometimes blindness if necessary medical treatment is not applied on time. |
2012-09-27 |
2023-08-12 |
Not clear |
| Elham Hatef, Afsheen Khwaja, Zubir Rentiya, Mohamed Ibrahim, Matthew Shulman, Peykan Turkcuoglu, Yasir Sepah, Jianmin Wang, Roomasa Channa, Millena Bittencourt, Abeer Akhtar, Jangwon Heo, Diana V Do, Quan Dong Nguye. Comparison of time domain and spectral domain optical coherence tomography in measurement of macular thickness in macular edema secondary to diabetic retinopathy and retinal vein occlusion. Journal of ophthalmology. vol 2012. 2012-08-23. PMID:22888403. |
in a prospective observational study at a university-based retina practice, retinal thickness tomography was performed simultaneously for fifty-eight patients (91 eyes) with dr and vo employing a time domain and two spectral domain octs. |
2012-08-23 |
2023-08-12 |
Not clear |
| U Rajendra Acharya, E Y K Ng, Jen-Hong Tan, S Vinitha Sree, Kwan-Hoong N. An integrated index for the identification of diabetic retinopathy stages using texture parameters. Journal of medical systems. vol 36. issue 3. 2012-08-16. PMID:21340703. |
prolonged diabetes damages the small blood vessels in the retina resulting in diabetic retinopathy (dr). |
2012-08-16 |
2023-08-12 |
human |
| Mohammad Shamsul Ola, Mohd Imtiaz Nawaz, M Mairaj Siddiquei, Saleh Al-Amro, Ahmed M Abu El-Asra. Recent advances in understanding the biochemical and molecular mechanism of diabetic retinopathy. Journal of diabetes and its complications. vol 26. issue 1. 2012-07-27. PMID:22226482. |
furthermore, we have highlighted neurodegeneration and regulation of neurotrophic factors, being recognized as early events that may be involved in the pathology of the disease in the course of dr. an understanding of the biochemical and molecular changes especially early in the diabetic retina may lead to new and effective therapies towards prevention and amelioration of dr, which is important for the millions of individuals who already have or are likely to develop the disease before a cure becomes available. |
2012-07-27 |
2023-08-12 |
human |