| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G B Arden, S Sivaprasa. The pathogenesis of early retinal changes of diabetic retinopathy. Documenta ophthalmologica. Advances in ophthalmology. vol 124. issue 1. 2012-07-10. PMID:22302291. |
this review explores the earliest changes to the retina in dr and the factors that predispose or prevent dr, including sleep apnoea, receptor degenerations laser treatment and vegf polymorphism. |
2012-07-10 |
2023-08-12 |
Not clear |
| Geoffrey B Arden, Sobha Sivaprasa. Hypoxia and oxidative stress in the causation of diabetic retinopathy. Current diabetes reviews. vol 7. issue 5. 2012-02-06. PMID:21916837. |
but the cells first affected in small animal models of dr are found throughout the inner retina, and not specifically associated with small blood vessels until later in the development of retinopathy. |
2012-02-06 |
2023-08-12 |
human |
| M H Ahmad Fadzil, Lila Iznita Izhar, Hermawan Nugroho, Hanung Adi Nugroh. Analysis of retinal fundus images for grading of diabetic retinopathy severity. Medical & biological engineering & computing. vol 49. issue 6. 2011-12-07. PMID:21271293. |
diabetic retinopathy (dr) is a sight threatening complication due to diabetes mellitus that affects the retina. |
2011-12-07 |
2023-08-12 |
Not clear |
| Johnny Tang, Timothy S Ker. Inflammation in diabetic retinopathy. Progress in retinal and eye research. vol 30. issue 5. 2011-11-21. PMID:21635964. |
diabetes causes a number of metabolic and physiologic abnormalities in the retina, but which of these abnormalities contribute to recognized features of diabetic retinopathy (dr) is less clear. |
2011-11-21 |
2023-08-12 |
Not clear |
| Olena Puzyeyeva, Wai Ching Lam, John G Flanagan, Michael H Brent, Robert G Devenyi, Mark S Mandelcorn, Tien Wong, Christopher Hudso. High-resolution optical coherence tomography retinal imaging: a case series illustrating potential and limitations. Journal of ophthalmology. vol 2011. 2011-11-10. PMID:21969910. |
using sd-oct, the cases of dr and brvo both exhibited macular edema with cystoid spaces visible in the outer retina. |
2011-11-10 |
2023-08-12 |
Not clear |
| Libuse Krizova, Marta Kalousova, Ales Kubena, Hana Benakova, Tomas Zima, Zdenek Kovarik, Jan Kalvoda, Bohdana Kalvodov. Increased uric acid and glucose concentrations in vitreous and serum of patients with diabetic macular oedema. Ophthalmic research. vol 46. issue 2. 2011-10-14. PMID:21242702. |
diabetic retinopathy (dr) is characterized by blood-retina barrier breakdown induced by local changes in the retina and systemic factors. |
2011-10-14 |
2023-08-12 |
Not clear |
| Gianni Virgili, Francesca Menchini, Vittoria Murro, Emanuela Peluso, Francesca Rosa, Giovanni Casazz. Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy. The Cochrane database of systematic reviews. issue 7. 2011-08-02. PMID:21735421. |
diabetic macular oedema (dmo) is a thickening of the central retina, or the macula, and is associated with long-term visual loss in people with diabetic retinopathy (dr). |
2011-08-02 |
2023-08-12 |
Not clear |
| b' Marta Villarroel, Andreea Ciudin, Cristina Hern\\xc3\\xa1ndez, Rafael Sim\\xc3\\xb. Neurodegeneration: An early event of diabetic retinopathy. World journal of diabetes. vol 1. issue 2. 2011-07-14. PMID:21537428.' |
diabetic retinopathy (dr) has been classically considered to be a microcirculatory disease of the retina caused by the deleterious metabolic effects of hyperglycemia per se and the metabolic pathways triggered by hyperglycemia. |
2011-07-14 |
2023-08-12 |
Not clear |
| Tetsuo Adachi, Hiroyuki Yasuda, Kazunari Aida, Tetsuro Kamiya, Hirokazu Hara, Ken-ichi Hosoya, Tetsuya Terasaki, Tsunehiko Iked. Regulation of extracellular-superoxide dismutase in rat retina pericytes. Redox report : communications in free radical research. vol 15. issue 6. 2011-05-09. PMID:21208524. |
diabetic retinopathy (dr) is regarded as a disease of the retinal microvascular system and metabolic abnormalities that are characteristic of oxidative stress and endoplasmic reticulum (er) stress have been identified in the retina. |
2011-05-09 |
2023-08-12 |
rat |
| M Ahmad Fadzil, Nor Fariza Ngah, Tara M George, Lila I Izhar, Hermawan Nugroho, Hanung Adi Nugroh. Analysis of foveal avascular zone in colour fundus images for grading of diabetic retinopathy severity. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2010. 2011-03-11. PMID:21097305. |
diabetic retinopathy (dr) is a sight threatening complication due to diabetes mellitus that affects the retina. |
2011-03-11 |
2023-08-12 |
Not clear |
| Suganthalakshmi Balasubbu, Periasamy Sundaresan, Anand Rajendran, Kim Ramasamy, Gowthaman Govindarajan, Namperumalsamy Perumalsamy, J Fielding Hejtmanci. Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy. BMC medical genetics. vol 11. 2010-12-30. PMID:21067572. |
diabetic retinopathy (dr) is classically defined as a microvasculopathy that primarily affects the small blood vessels of the inner retina as a complication of diabetes mellitus (dm).it is a multifactorial disease with a strong genetic component. |
2010-12-30 |
2023-08-12 |
Not clear |
| Yingfeng Zheng, Tien Y Wong, Carol Yim-Lui Cheung, Ecosse Lamoureux, Paul Mitchell, Mingguang He, Tin Aun. Influence of diabetes and diabetic retinopathy on the performance of Heidelberg retina tomography II for diagnosis of glaucoma. Investigative ophthalmology & visual science. vol 51. issue 11. 2010-12-07. PMID:20538993. |
to determine whether diabetes and diabetic retinopathy (dr) affect the performance of the heidelberg retina tomograph ii (hrt ii; heidelberg engineering, heidelberg, germany) algorithms for glaucoma detection. |
2010-12-07 |
2023-08-12 |
Not clear |
| Vidhya R Rao, Elizabeth Prescott, Namdev B Shelke, Ruchit Trivedi, Peter Thomas, Craig Struble, Tom Gadek, Charles A O'Neill, Uday B Kompell. Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR). Investigative ophthalmology & visual science. vol 51. issue 10. 2010-10-19. PMID:20445119. |
delivery of sar 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (stz) model of diabetic retinopathy (dr). |
2010-10-19 |
2023-08-12 |
rat |
| Hille W van Dijk, Frank D Verbraak, Pauline H B Kok, Mona K Garvin, Milan Sonka, Kyungmoo Lee, J Hans Devries, Robert P J Michels, Mirjam E J van Velthoven, Reinier O Schlingemann, Michael D Abràmof. Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes. Investigative ophthalmology & visual science. vol 51. issue 7. 2010-08-02. PMID:20130282. |
to determine which retinal layers are most affected by diabetes and contribute to thinning of the inner retina and to investigate the relationship between retinal layer thickness (lt) and diabetes duration, diabetic retinopathy (dr) status, age, glycosylated hemoglobin (hba1c), and the sex of the individual, in patients with type 1 diabetes who have no or minimal dr. methods. |
2010-08-02 |
2023-08-12 |
human |
| Hille W van Dijk, Frank D Verbraak, Pauline H B Kok, Mona K Garvin, Milan Sonka, Kyungmoo Lee, J Hans Devries, Robert P J Michels, Mirjam E J van Velthoven, Reinier O Schlingemann, Michael D Abràmof. Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes. Investigative ophthalmology & visual science. vol 51. issue 7. 2010-08-02. PMID:20130282. |
these results support the concept that diabetes has an early neurodegenerative effect on the retina, which occurs even though the vascular component of dr is minimal. |
2010-08-02 |
2023-08-12 |
human |
| Michael D Abramoff, Meindert Niemeijer, Stephen R Russel. Automated detection of diabetic retinopathy: barriers to translation into clinical practice. Expert review of medical devices. vol 7. issue 2. 2010-06-09. PMID:20214432. |
automated identification of diabetic retinopathy (dr), the primary cause of blindness and visual loss for those aged 18-65 years, from color images of the retina has enormous potential to increase the quality, cost-effectiveness and accessibility of preventative care for people with diabetes. |
2010-06-09 |
2023-08-12 |
human |
| Ai-hua Yuan, Yan Mei, Hong-ying Zhou, Tao Xiang, Hui-jun Yan. [Expression pattern of nitric oxide synthase in the retina of diabetic rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 27. issue 4. 2010-05-11. PMID:17545029. |
to investigate the expression of nitric oxide synthase (nos) in the retina of 8-week-old diabetic rats, and explore the potential molecular mechanisms for the role of no in diabetic retinopathy (dr). |
2010-05-11 |
2023-08-12 |
rat |
| Silvia Landi, Maria Cristina Cenni, Lamberto Maffei, Nicoletta Berard. Environmental enrichment effects on development of retinal ganglion cell dendritic stratification require retinal BDNF. PloS one. vol 2. issue 4. 2010-04-19. PMID:17406670. |
ee precociously increases brain derived neurotrophic factor (bdnf) in the retina, in parallel with the precocious segregation of rgc dendrites; in addition, ee counteracts retinal bdnf reduction in dr retinas and promotes a normal segregation of rgc dendrites. |
2010-04-19 |
2023-08-12 |
mouse |
| Hisanori Imai, Ravi S J Singh, Patrice E Fort, Thomas W Gardne. Neuroprotection for diabetic retinopathy. Developments in ophthalmology. vol 44. 2009-12-11. PMID:19494653. |
diabetic retinopathy (dr) is a neurodegenerative and microvascular disease resulting in functional and structural changes of all cell types in the retina. |
2009-12-11 |
2023-08-12 |
Not clear |
| Hisanori Imai, Ravi S J Singh, Patrice E Fort, Thomas W Gardne. Neuroprotection for diabetic retinopathy. Developments in ophthalmology. vol 44. 2009-12-11. PMID:19494653. |
several mechanisms for neuroretinal homeostasis, including the blood-retinal barrier, normal metabolite delivery into the retina, and the effect of neurotrophins for the retina, are impaired in dr. |
2009-12-11 |
2023-08-12 |
Not clear |