| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Floride Niyuhire, Stephen A Varvel, Billy R Martin, Aron H Lichtma. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17586723. |
although delta(9)-thc and other cannabinoids disrupt performance in a wide range of animal models of learning and memory, few studies have investigated the effects of smoked marijuana in these paradigms. |
2007-10-19 |
2023-08-12 |
mouse |
| Floride Niyuhire, Stephen A Varvel, Billy R Martin, Aron H Lichtma. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17586723. |
in the present study, we investigated the specific effects of marijuana smoke and injected delta(9)-thc on acquisition versus memory retrieval in a mouse repeated acquisition morris water-maze task. |
2007-10-19 |
2023-08-12 |
mouse |
| Floride Niyuhire, Stephen A Varvel, Billy R Martin, Aron H Lichtma. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17586723. |
to distinguish between these processes, subjects were administered delta(9)-thc or they were exposed to marijuana smoke either 30 min before acquisition or 30 min before the retention test. |
2007-10-19 |
2023-08-12 |
mouse |
| Floride Niyuhire, Stephen A Varvel, Billy R Martin, Aron H Lichtma. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17586723. |
inhalation of marijuana smoke or injected delta(9)-thc impaired the ability of the mice to learn the location of the hidden platform and to recall the platform location once learning had already taken place. |
2007-10-19 |
2023-08-12 |
mouse |
| Floride Niyuhire, Stephen A Varvel, Billy R Martin, Aron H Lichtma. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17586723. |
finally, the cannabinoid-1 (cb(1)) receptor antagonist n-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide hcl (rimonabant) blocked the memory disruptive effects of both delta(9)-thc and marijuana. |
2007-10-19 |
2023-08-12 |
mouse |
| Xuefeng Zhang, Jian Feng Wang, George Kunos, Jerome E Groopma. Cannabinoid modulation of Kaposi's sarcoma-associated herpesvirus infection and transformation. Cancer research. vol 67. issue 15. 2007-09-11. PMID:17671191. |
marijuana is a widely used recreational agent, and delta(9)-tetrahydrocannabinol (delta(9)-thc), the major active component of marijuana, is prescribed for medicinal use. |
2007-09-11 |
2023-08-12 |
human |
| Eric J Downer, Aoife Gowran, Aine C Murphy, Veronica A Campbel. The tumour suppressor protein, p53, is involved in the activation of the apoptotic cascade by Delta9-tetrahydrocannabinol in cultured cortical neurons. European journal of pharmacology. vol 564. issue 1-3. 2007-08-17. PMID:17379209. |
delta(9)-tetrahydrocannabinol, the psychoactive ingredient of marijuana, regulates a variety of neuronal processes including neurotransmitter release and synaptic transmission. |
2007-08-17 |
2023-08-12 |
Not clear |
| Marie Velenovská, Zdenek Fisa. Effect of cannabinoids on platelet serotonin uptake. Addiction biology. vol 12. issue 2. 2007-08-17. PMID:17508987. |
the effect of delta(9)-tetrahydrocannabinol (delta(9)-thc), endocannabinoid anandamide and synthetic cannabinoid receptor agonist win 55,212-2 on platelet serotonin uptake and membrane microviscosity was examined in 19 marijuana smokers and 20 controls. |
2007-08-17 |
2023-08-12 |
Not clear |
| A Glaz-Sandberg, L Dietz, H Nguyen, H Oberwittler, Rolf Aderjan, Gerd Miku. Pharmacokinetics of 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol (CTHC) after intravenous administration of CTHC in healthy human subjects. Clinical pharmacology and therapeutics. vol 82. issue 1. 2007-08-16. PMID:17410118. |
after cannabis consumption there is only limited knowledge about the pharmacokinetic (pk) and metabolic properties of 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol (cthc), which is formed by oxidative breakdown from delta(9)-tetrahydrocannabinol (thc). |
2007-08-16 |
2023-08-12 |
human |
| T Lorivel, P Hilbe. Motor effects of delta 9 THC in cerebellar Lurcher mutant mice. Behavioural brain research. vol 181. issue 2. 2007-08-16. PMID:17531329. |
the present study evaluated the effects of the principal active component of marijuana (delta 9 thc) on motor abilities and motor learning in mice with cerebellar dysfunction. |
2007-08-16 |
2023-08-12 |
mouse |
| Tong-Rong Jan, Shu-Ting Su, Hsin-Ying Wu, Mei-Hsiu Lia. Suppressive effects of cannabidiol on antigen-specific antibody production and functional activity of splenocytes in ovalbumin-sensitized BALB/c mice. International immunopharmacology. vol 7. issue 6. 2007-08-06. PMID:17466911. |
because the immune system has been widely demonstrated to be affected by psychoactive cannabinoids, such as delta(9)-tetrahydrocannabinol, the objective of the present studies is to investigate the immunomodulatory effect of cbd, the major non-psychoactive cannabinoid in marijuana. |
2007-08-06 |
2023-08-12 |
mouse |
| Christine Moore, Sumandeep Rana, Cynthia Coulte. Simultaneous identification of 2-carboxy-tetrahydrocannabinol, tetrahydrocannabinol, cannabinol and cannabidiol in oral fluid. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 852. issue 1-2. 2007-08-01. PMID:17321807. |
we present an analytical procedure for the simultaneous determination of the pyrolytic precursor delta(9)-tetrahydrocannabinolic acid a, tetrahydrocannabinol, cannabinol and cannabidiol in human oral fluid specimens using gas chromatography mass spectrometry (gc/ms). |
2007-08-01 |
2023-08-12 |
human |
| J Davey, N Leal, J Freema. Screening for drugs in oral fluid: illicit drug use and drug driving in a sample of Queensland motorists. Drug and alcohol review. vol 26. issue 3. 2007-08-01. PMID:17454020. |
illicit substances tested for included cannabis (delta 9 tetrahydrocannibinol [thc]), amphetamine type substances, heroin and cocaine. |
2007-08-01 |
2023-08-12 |
human |
| J Davey, N Leal, J Freema. Screening for drugs in oral fluid: illicit drug use and drug driving in a sample of Queensland motorists. Drug and alcohol review. vol 26. issue 3. 2007-08-01. PMID:17454020. |
the most common drugs detected in oral fluid were cannabis (delta 9 thc) (n = 13) followed by amphetamine type substances (n = 11). |
2007-08-01 |
2023-08-12 |
human |
| Margaret Hane. Opioid antagonism of cannabinoid effects: differences between marijuana smokers and nonmarijuana smokers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 6. 2007-07-27. PMID:17091128. |
in non-human animals, opioid antagonists block the reinforcing and discriminative-stimulus effects of delta(9)-tetrahydrocannabinol (thc), while in human marijuana smokers, naltrexone (50 mg) enhances the reinforcing and subjective effects of thc. |
2007-07-27 |
2023-08-12 |
human |
| Gerold F Kauert, Johannes G Ramaekers, Erhard Schneider, Manfred R Moeller, Stefan W Toenne. Pharmacokinetic properties of delta9-tetrahydrocannabinol in serum and oral fluid. Journal of analytical toxicology. vol 31. issue 5. 2007-07-27. PMID:17579974. |
in a study on the effects of smoked cannabis (18.2 +/- 2.8 mg as low and 36.5 +/- 5.6 mg as high dose) paired blood and oral fluid samples were collected from 10 study participants up to 6 h after smoking and analyzed for the cannabinoids delta(9)-tetrahydrocannabinol (thc), 11-hydroxy-thc (thc-oh) and 11-nor-9-carboxy-thc (thca) using gas chromatography-mass spectrometry. |
2007-07-27 |
2023-08-12 |
human |
| Sandra B Grauwiler, André Scholer, Jürgen Drew. Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 850. issue 1-2. 2007-07-24. PMID:17236827. |
a novel high-performance liquid chromatographic separation method with tandem-mass spectrometry detection was developed for the simultaneous determination of delta(9)-tetrahydrocannabinol (thc) and its major metabolites 11-hydroxy-delta(9)-tetrahydrocannabinol (11-oh-thc) and 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid (thc-cooh) as well as the components cannabidiol (cbd) and cannabinol (cbn) in human edta-plasma and urine. |
2007-07-24 |
2023-08-12 |
human |
| Sandra B Grauwiler, André Scholer, Jürgen Drew. Development of a LC/MS/MS method for the analysis of cannabinoids in human EDTA-plasma and urine after small doses of Cannabis sativa extracts. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 850. issue 1-2. 2007-07-24. PMID:17236827. |
the method was successfully applied to the determination of cannabinoids in human plasma and human urine after administration of delta(9)-tetrahydrocannabinol or cannabis sativa extracts. |
2007-07-24 |
2023-08-12 |
human |
| Alexander F Hoffman, Murat Oz, Ruiqin Yang, Aron H Lichtman, Carl R Lupic. Opposing actions of chronic Delta9-tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-term potentiation. Learning & memory (Cold Spring Harbor, N.Y.). vol 14. issue 1-2. 2007-07-03. PMID:17202425. |
memory deficits produced by marijuana arise partly via interaction of the psychoactive component, delta(9)-tetrahydrocannabinol (delta(9)-thc), with cannabinoid receptors in the hippocampus. |
2007-07-03 |
2023-08-12 |
rat |
| Kazuhide Hayakawa, Kenichi Mishima, Masanori Nozako, Mai Hazekawa, Ayumi Ogata, Masayuki Fujioka, Kazuhiko Harada, Shohei Mishima, Kensuke Orito, Nobuaki Egashira, Katunori Iwasaki, Michihiro Fujiwar. Delta9-tetrahydrocannabinol (Delta9-THC) prevents cerebral infarction via hypothalamic-independent hypothermia. Life sciences. vol 80. issue 16. 2007-06-28. PMID:17289082. |
delta(9)-tetrahydrocannabinol (delta(9)-thc), a primary psychoactive constituent of cannabis, has been reported to act as a neuroprotectant via the cannabinoid cb(1) receptor. |
2007-06-28 |
2023-08-12 |
mouse |