| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Bonechi, S Martini, V Brizzi, A Brizzi, P Massarelli, G Bruni, C Ross. Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. European journal of medicinal chemistry. vol 41. issue 10. 2007-01-26. PMID:16837109. |
the understanding of the molecular basis of cannabinoid activity has greatly improved since the discovery of cb1 and cb2 receptors. |
2007-01-26 |
2023-08-12 |
rat |
| Leos Landa, Alexandra Sulcova, Karel Slai. Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. Neuro endocrinology letters. vol 27. issue 1-2. 2007-01-17. PMID:16648795. |
involvement of cannabinoid cb1 and cb2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. |
2007-01-17 |
2023-08-12 |
mouse |
| Saori Oka, Junichi Wakui, Shinobu Ikeda, Shin Yanagimoto, Seishi Kishimoto, Maiko Gokoh, Miwako Nasui, Takayuki Sugiur. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 12. 2007-01-16. PMID:17142782. |
involvement of the cannabinoid cb2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. |
2007-01-16 |
2023-08-12 |
mouse |
| Saori Oka, Junichi Wakui, Shinobu Ikeda, Shin Yanagimoto, Seishi Kishimoto, Maiko Gokoh, Miwako Nasui, Takayuki Sugiur. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 12. 2007-01-16. PMID:17142782. |
the possible involvement of 2-arachidonoylglycerol (2-ag), an endogenous ligand for the cannabinoid receptors (cb1 and cb2), in contact dermatitis in mouse ear was investigated. |
2007-01-16 |
2023-08-12 |
mouse |
| Mehdi Ghasemi, Hamed Sadeghipour, Ali R Mani, Sina Tavakoli, Amir Reza Hajrasouliha, Farzad Ebrahimi, Ahmad Reza Dehpou. Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. European journal of pharmacology. vol 544. issue 1-3. 2007-01-12. PMID:16824514. |
the potentiating effect of anandamide (1 microm) on relaxation responses was significantly attenuated by either the selective cannabinoid cb1 receptor antagonist n-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide (am251; 1 microm) or the vanilloid receptor antagonist capsazepine (3 microm), but not by the selective cannabinoid cb2 receptor antagonist 6-iodo-2-methyl-1-[2-(4-morpholinyl) ethyl]-1h-indol-3-yl (4-methoxyphenyl)methanone (am630; 1 microm). |
2007-01-12 |
2023-08-12 |
rat |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
discovery of the presence and functional expression of cannabinoid cb2 receptors in brain. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
two well-characterized cannabinoid receptors (cbrs), cb1 and cb2, mediate the effects of cannabinoids and marijuana use, with functional evidence for other cbrs. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
we have reported the discovery and functional presence of cb2 cannabinoid receptors in mammalian brain that may be involved in depression and drug abuse and this was supported by reports of identification of neuronal cb2 receptors that are involved in emesis. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
the effect of direct cb2 antisense oligonucleotide injection into the brain and treatment with jwh015 in motor function and plus-maze tests also demonstrated the functional presence of cb2 cannabinoid receptors in the central nervous system (cns). |
2007-01-10 |
2023-08-12 |
mouse |
| B B Yao, S Mukherjee, Y Fan, T R Garrison, A V Daza, G K Grayson, B A Hooker, M J Dart, J P Sullivan, M D Meye. In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? British journal of pharmacology. vol 149. issue 2. 2007-01-09. PMID:16894349. |
in vitro pharmacological characterization of am1241: a protean agonist at the cannabinoid cb2 receptor? |
2007-01-09 |
2023-08-12 |
Not clear |
| Cristina Blázquez, Arkaitz Carracedo, Lucía Barrado, Pedro José Real, José Luis Fernández-Luna, Guillermo Velasco, Marcos Malumbres, Manuel Guzmá. Cannabinoid receptors as novel targets for the treatment of melanoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 14. 2007-01-01. PMID:17065222. |
human melanomas and melanoma cell lines express cb1 and cb2 cannabinoid receptors. |
2007-01-01 |
2023-08-12 |
mouse |
| Angelo Jayamanne, Ruth Greenwood, Vanessa A Mitchell, Sevda Aslan, Daniele Piomelli, Christopher W Vaugha. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. British journal of pharmacology. vol 147. issue 3. 2006-12-26. PMID:16331291. |
the effects of urb597 in the cfa model were dose dependent and were reduced by coadministration with the cannabinoid cb1 antagonist am251 (1 mg kg(-1)), or the cb2 and sr144528 (1 mg kg(-1)). |
2006-12-26 |
2023-08-12 |
rat |
| Angelo Jayamanne, Ruth Greenwood, Vanessa A Mitchell, Sevda Aslan, Daniele Piomelli, Christopher W Vaugha. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. British journal of pharmacology. vol 147. issue 3. 2006-12-26. PMID:16331291. |
these findings suggest that the faah inhibitor urb597 produces cannabinoid cb1 and cb2 receptor-mediated analgesia in inflammatory pain states, without causing the undesirable side effects associated with cannabinoid receptor activation. |
2006-12-26 |
2023-08-12 |
rat |
| Paola Nieri, Nadia Romiti, Barbara Adinolfi, Andrea Chicca, Ilaria Massarelli, Elisabetta Chiel. Modulation of P-glycoprotein activity by cannabinoid molecules in HK-2 renal cells. British journal of pharmacology. vol 148. issue 5. 2006-12-26. PMID:16715117. |
rt-pcr demonstrated that hk-2 cells do not express cb1 or cb2 cannabinoid receptors. |
2006-12-26 |
2023-08-12 |
Not clear |
| Régis Roche, Laurence Hoareau, Sandrine Bes-Houtmann, Marie-Paule Gonthier, Christine Laborde, Jean-François Baron, Yacine Haffaf, Maya Cesari, Franck Fest. Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes. Histochemistry and cell biology. vol 126. issue 2. 2006-12-15. PMID:16395612. |
presence of the cannabinoid receptors, cb1 and cb2, in human omental and subcutaneous adipocytes. |
2006-12-15 |
2023-08-12 |
human |
| Xundi Xu, Yi Liu, Shengfu Huang, Guoxing Liu, Chengzhi Xie, Jun Zhou, Wentao Fan, Qinglong Li, Qunwei Wang, Dewu Zhong, Xiongying Mia. Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. Cancer genetics and cytogenetics. vol 171. issue 1. 2006-12-15. PMID:17074588. |
overexpression of cannabinoid receptors cb1 and cb2 correlates with improved prognosis of patients with hepatocellular carcinoma. |
2006-12-15 |
2023-08-12 |
human |
| Xundi Xu, Yi Liu, Shengfu Huang, Guoxing Liu, Chengzhi Xie, Jun Zhou, Wentao Fan, Qinglong Li, Qunwei Wang, Dewu Zhong, Xiongying Mia. Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. Cancer genetics and cytogenetics. vol 171. issue 1. 2006-12-15. PMID:17074588. |
our results indicate that cb1 and cb2 have potential as prognostic indicators and suggest possible beneficial effects of cannabinoids on prognosis of patients with hcc. |
2006-12-15 |
2023-08-12 |
human |
| Kathline Kim, Dan H Moore, Alexandros Makriyannis, Mary E Aboo. AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. European journal of pharmacology. vol 542. issue 1-3. 2006-12-14. PMID:16781706. |
am1241, a cannabinoid cb2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. |
2006-12-14 |
2023-08-12 |
mouse |
| Kathline Kim, Dan H Moore, Alexandros Makriyannis, Mary E Aboo. AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. European journal of pharmacology. vol 542. issue 1-3. 2006-12-14. PMID:16781706. |
am1241 is a cannabinoid cb2 receptor selective agonist that has been shown to be effective in models of inflammation and hyperalgesia. |
2006-12-14 |
2023-08-12 |
mouse |
| Kathline Kim, Dan H Moore, Alexandros Makriyannis, Mary E Aboo. AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. European journal of pharmacology. vol 542. issue 1-3. 2006-12-14. PMID:16781706. |
as am1241 was well tolerated by the animals, cannabinoid cb2 receptor-selective compounds may be the basis for developing new drugs for the treatment of als and other chronic neurodegenerative diseases. |
2006-12-14 |
2023-08-12 |
mouse |