| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshifumi Ueda, Naoki Miyagawa, Korekiyo Wakitan. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life sciences. vol 80. issue 5. 2007-02-20. PMID:17055000. |
involvement of cannabinoid cb2 receptors in the ige-mediated cutaneous reaction was investigated. |
2007-02-20 |
2023-08-12 |
mouse |
| Yoshifumi Ueda, Naoki Miyagawa, Korekiyo Wakitan. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life sciences. vol 80. issue 5. 2007-02-20. PMID:17055000. |
in contrast, cannabinoid cb2 receptor-deficient mice failed to exhibit the obvious triphasic ear swelling observed in wild-type mice. |
2007-02-20 |
2023-08-12 |
mouse |
| Yoshifumi Ueda, Naoki Miyagawa, Korekiyo Wakitan. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life sciences. vol 80. issue 5. 2007-02-20. PMID:17055000. |
oral administration of cannabinoid cb2 receptor antagonist/inverse agonists [n-(benzo[1,3]dioxol-5-ylmethyl)-7-methoxy-2-oxo-8-pentyloxy-1,2-dihydroquinoline-3-carboxamide] (jte-907) and {n-[(1s)-endo-1,3,3-trimethylbicyclo[2,2,1]heptan-2yl]5-(4-chloro-3-methyl-phenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide} (sr144528) at doses of 0.1-10 mg/kg significantly and dose-dependently suppressed all three phases of ear swelling in balb/c mice. |
2007-02-20 |
2023-08-12 |
mouse |
| Yoshifumi Ueda, Naoki Miyagawa, Korekiyo Wakitan. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life sciences. vol 80. issue 5. 2007-02-20. PMID:17055000. |
these results suggest that cannabinoid cb2 receptors are involved in induction of the triphasic cutaneous reaction mediated by ige, and that cannabinoid cb2 receptor antagonist/inverse agonists may serve as anti-allergic agents in the treatment of allergic dermatitis. |
2007-02-20 |
2023-08-12 |
mouse |
| A Scutt, E M Williamso. Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors. Calcified tissue international. vol 80. issue 1. 2007-02-20. PMID:17205329. |
cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via cb2 receptors. |
2007-02-20 |
2023-08-12 |
Not clear |
| Leos Landa, Karel Slais, Alexandra Sulcov. Impact of cannabinoid receptor ligands on behavioural sensitization to antiaggressive methamphetamine effects in the model of mouse agonistic behaviour. Neuro endocrinology letters. vol 27. issue 6. 2007-02-15. PMID:17187025. |
the present study was focused on a possible sensitisation to antiaggressive effect of methamphetamine and cross-sensitization to this effect after repeated pre-treatment with cannabinoid cb1 and cb2 receptor ligands with different intrinsic activity (cb1 agonist methanandamide, cb2 agonist jwh 015, and cb1 antagonist am 251). |
2007-02-15 |
2023-08-12 |
mouse |
| C Velez-Pardo, M Jimenez Del Ri. Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K-dependent mechanisms: role of NF-kappaB and p53. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 2. issue 5. 2007-01-30. PMID:17017986. |
the present study shows that cp55,940 (a cb1 and cb2 agonist) and jwh-015 (a cb2 agonist) protect and rescue peripheral blood lymphocytes (pbl) from (10 microm) abeta[(25-35)] and (50 microm) h(2)o(2)-induced apoptosis by two alternative mechanisms: (1) receptor-independent pathway, as demonstrated by no-dihydrorhodamine oxidation into fluorescent rhodamine 123 (r-123) as a result of cannabinoid inhibition of abeta-generated h(2)o(2); (2) receptor-dependent pathway through nf-kappab activation and p53 down regulation involving phosphoinositide 3-kinase (pi-3k), as demonstrated by using either (25 microm) ly294002 (a pi-3k inhibitor), (50 nm) pifithrin-alpha (pft, a specific p53 inhibitor) or by using immunocytochemistry detection of nf-kappab and p53 transcription factors activation. |
2007-01-30 |
2023-08-12 |
Not clear |
| C Bonechi, S Martini, V Brizzi, A Brizzi, P Massarelli, G Bruni, C Ross. Nuclear magnetic resonance for studying recognition processes between anandamide and cannabinoid receptors. European journal of medicinal chemistry. vol 41. issue 10. 2007-01-26. PMID:16837109. |
the understanding of the molecular basis of cannabinoid activity has greatly improved since the discovery of cb1 and cb2 receptors. |
2007-01-26 |
2023-08-12 |
rat |
| Leos Landa, Alexandra Sulcova, Karel Slai. Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. Neuro endocrinology letters. vol 27. issue 1-2. 2007-01-17. PMID:16648795. |
involvement of cannabinoid cb1 and cb2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. |
2007-01-17 |
2023-08-12 |
mouse |
| Saori Oka, Junichi Wakui, Shinobu Ikeda, Shin Yanagimoto, Seishi Kishimoto, Maiko Gokoh, Miwako Nasui, Takayuki Sugiur. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 12. 2007-01-16. PMID:17142782. |
involvement of the cannabinoid cb2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. |
2007-01-16 |
2023-08-12 |
mouse |
| Saori Oka, Junichi Wakui, Shinobu Ikeda, Shin Yanagimoto, Seishi Kishimoto, Maiko Gokoh, Miwako Nasui, Takayuki Sugiur. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachidonoylglycerol in oxazolone-induced contact dermatitis in mice. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 12. 2007-01-16. PMID:17142782. |
the possible involvement of 2-arachidonoylglycerol (2-ag), an endogenous ligand for the cannabinoid receptors (cb1 and cb2), in contact dermatitis in mouse ear was investigated. |
2007-01-16 |
2023-08-12 |
mouse |
| Mehdi Ghasemi, Hamed Sadeghipour, Ali R Mani, Sina Tavakoli, Amir Reza Hajrasouliha, Farzad Ebrahimi, Ahmad Reza Dehpou. Effect of anandamide on nonadrenergic noncholinergic-mediated relaxation of rat corpus cavernosum. European journal of pharmacology. vol 544. issue 1-3. 2007-01-12. PMID:16824514. |
the potentiating effect of anandamide (1 microm) on relaxation responses was significantly attenuated by either the selective cannabinoid cb1 receptor antagonist n-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2, 4-dichlorophenyl)-4-methyl-1h-pyrazole-3-carboxamide (am251; 1 microm) or the vanilloid receptor antagonist capsazepine (3 microm), but not by the selective cannabinoid cb2 receptor antagonist 6-iodo-2-methyl-1-[2-(4-morpholinyl) ethyl]-1h-indol-3-yl (4-methoxyphenyl)methanone (am630; 1 microm). |
2007-01-12 |
2023-08-12 |
rat |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
discovery of the presence and functional expression of cannabinoid cb2 receptors in brain. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
two well-characterized cannabinoid receptors (cbrs), cb1 and cb2, mediate the effects of cannabinoids and marijuana use, with functional evidence for other cbrs. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
we have reported the discovery and functional presence of cb2 cannabinoid receptors in mammalian brain that may be involved in depression and drug abuse and this was supported by reports of identification of neuronal cb2 receptors that are involved in emesis. |
2007-01-10 |
2023-08-12 |
mouse |
| Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Alex Perchuk, Paul A Meozzi, Lester Myers, Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco, Babatunde E Akinshola, Qing-Rong Liu, Bruce Hope, Shinya Iwasaki, Tadao Arinami, Lindsey Teasenfitz, George R Uh. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105950. |
the effect of direct cb2 antisense oligonucleotide injection into the brain and treatment with jwh015 in motor function and plus-maze tests also demonstrated the functional presence of cb2 cannabinoid receptors in the central nervous system (cns). |
2007-01-10 |
2023-08-12 |
mouse |
| B B Yao, S Mukherjee, Y Fan, T R Garrison, A V Daza, G K Grayson, B A Hooker, M J Dart, J P Sullivan, M D Meye. In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? British journal of pharmacology. vol 149. issue 2. 2007-01-09. PMID:16894349. |
in vitro pharmacological characterization of am1241: a protean agonist at the cannabinoid cb2 receptor? |
2007-01-09 |
2023-08-12 |
Not clear |
| Cristina Blázquez, Arkaitz Carracedo, Lucía Barrado, Pedro José Real, José Luis Fernández-Luna, Guillermo Velasco, Marcos Malumbres, Manuel Guzmá. Cannabinoid receptors as novel targets for the treatment of melanoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 14. 2007-01-01. PMID:17065222. |
human melanomas and melanoma cell lines express cb1 and cb2 cannabinoid receptors. |
2007-01-01 |
2023-08-12 |
mouse |
| Angelo Jayamanne, Ruth Greenwood, Vanessa A Mitchell, Sevda Aslan, Daniele Piomelli, Christopher W Vaugha. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. British journal of pharmacology. vol 147. issue 3. 2006-12-26. PMID:16331291. |
the effects of urb597 in the cfa model were dose dependent and were reduced by coadministration with the cannabinoid cb1 antagonist am251 (1 mg kg(-1)), or the cb2 and sr144528 (1 mg kg(-1)). |
2006-12-26 |
2023-08-12 |
rat |
| Angelo Jayamanne, Ruth Greenwood, Vanessa A Mitchell, Sevda Aslan, Daniele Piomelli, Christopher W Vaugha. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. British journal of pharmacology. vol 147. issue 3. 2006-12-26. PMID:16331291. |
these findings suggest that the faah inhibitor urb597 produces cannabinoid cb1 and cb2 receptor-mediated analgesia in inflammatory pain states, without causing the undesirable side effects associated with cannabinoid receptor activation. |
2006-12-26 |
2023-08-12 |
rat |