Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Nova M H Sain, Annie Liang, Stefanie A Kane, Mark O Urba. Antinociceptive effects of the non-selective cannabinoid receptor agonist CP 55,940 are absent in CB1(-/-) and not CB2(-/-) mice in models of acute and persistent pain. Neuropharmacology. vol 57. issue 3. 2009-11-27. PMID:19538975. |
previous studies have suggested a role for both cb1 and cb2 cannabinoid receptors in modulation of nociception. |
2009-11-27 |
2023-08-12 |
mouse |
Cassandra I Saunders, Robert G Fassett, Dominic P Geraght. Up-regulation of TRPV1 in mononuclear cells of end-stage kidney disease patients increases susceptibility to N-arachidonoyl-dopamine (NADA)-induced cell death. Biochimica et biophysica acta. vol 1792. issue 10. 2009-11-25. PMID:19619644. |
trpv1 (5'-iodoresiniferatoxin) and cannabinoid (cb2; am630) receptor antagonists blocked the cytotoxic effect of nada. |
2009-11-25 |
2023-08-12 |
Not clear |
Nicola H Morgan, Ian M Stanford, Gavin L Woodhal. Functional CB2 type cannabinoid receptors at CNS synapses. Neuropharmacology. vol 57. issue 4. 2009-11-24. PMID:19616018. |
functional cb2 type cannabinoid receptors at cns synapses. |
2009-11-24 |
2023-08-12 |
rat |
Nicola H Morgan, Ian M Stanford, Gavin L Woodhal. Functional CB2 type cannabinoid receptors at CNS synapses. Neuropharmacology. vol 57. issue 4. 2009-11-24. PMID:19616018. |
however, evidence for the expression of cb2 type cannabinoid receptors at neuronal sites in the cns is building through anatomical localization of receptors and mrna in neurons and behavioural studies of central effects of cb2r agonists. |
2009-11-24 |
2023-08-12 |
rat |
J J Galliga. Cannabinoid signalling in the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 21. issue 9. 2009-11-23. PMID:19689654. |
exogenous cannabinoids and endocannabinoids act on cb1 and cb2 receptors. |
2009-11-23 |
2023-08-12 |
Not clear |
J J Galliga. Cannabinoid signalling in the enteric nervous system. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. vol 21. issue 9. 2009-11-23. PMID:19689654. |
cb2 receptors are expressed by immune cells and cannabinoids can suppress immune function. |
2009-11-23 |
2023-08-12 |
Not clear |
Vanessa Deveaux, Thomas Cadoudal, Yasukatsu Ichigotani, Fatima Teixeira-Clerc, Alexandre Louvet, Sylvie Manin, Jeanne Tran-Van Nhieu, Marie Pierre Belot, Andreas Zimmer, Patrick Even, Patrice D Cani, Claude Knauf, Remy Burcelin, Adeline Bertola, Yannick Le Marchand-Brustel, Philippe Gual, Ariane Mallat, Sophie Lotersztaj. Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis. PloS one. vol 4. issue 6. 2009-11-17. PMID:19513120. |
cannabinoid cb2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis. |
2009-11-17 |
2023-08-12 |
Not clear |
Andrea Chicca, Stefan Raduner, Federica Pellati, Thomas Strompen, Karl-Heinz Altmann, Roland Schoop, Jürg Gertsc. Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts. International immunopharmacology. vol 9. issue 7-8. 2009-11-13. PMID:19303464. |
we show that n-alkylamides act in concert and exert pleiotropic effects modulating the endocannabinoid system by simultaneously targeting the cb2 receptor, endocannabinoid transport and degradation. |
2009-11-13 |
2023-08-12 |
human |
b' Bal\\xc3\\xa1zs Cs\\xc3\\xb3ka, Zolt\\xc3\\xa1n H N\\xc3\\xa9meth, Partha Mukhopadhyay, Zolt\\xc3\\xa1n Spolarics, Mohanraj Rajesh, Stephanie Federici, Edwin A Deitch, S\\xc3\\xa1ndor B\\xc3\\xa1tkai, P\\xc3\\xa1l Pacher, Gy\\xc3\\xb6rgy Hask\\xc3\\xb. CB2 cannabinoid receptors contribute to bacterial invasion and mortality in polymicrobial sepsis. PloS one. vol 4. issue 7. 2009-11-10. PMID:19641602.' |
cb2 cannabinoid receptors contribute to bacterial invasion and mortality in polymicrobial sepsis. |
2009-11-10 |
2023-08-12 |
Not clear |
Rosa María Tolón, Estefanía Núñez, María Ruth Pazos, Cristina Benito, Ana Isabel Castillo, José Antonio Martínez-Orgado, Julián Romer. The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. Brain research. vol 1283. 2009-10-23. PMID:19505450. |
the activation of cannabinoid cb2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages. |
2009-10-23 |
2023-08-12 |
human |
Alexander A Zoerner, Frank M Gutzki, Maria T Suchy, Bibiana Beckmann, Stefan Engeli, Jens Jordan, Dimitrios Tsika. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 877. issue 26. 2009-09-28. PMID:19414283. |
anandamide (arachidonoyl ethanol amide, aea) is an endocannabinoid, acting on cb1 and cb2 receptors. |
2009-09-28 |
2023-08-12 |
human |
N Olea-Herrero, D Vara, S Malagarie-Cazenave, I Díaz-Laviad. Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2. British journal of cancer. vol 101. issue 6. 2009-09-23. PMID:19690545. |
inhibition of human tumour prostate pc-3 cell growth by cannabinoids r(+)-methanandamide and jwh-015: involvement of cb2. |
2009-09-23 |
2023-08-12 |
human |
Leonie Wyffels, Giulio G Muccioli, Sylvie De Bruyne, Lieselotte Moerman, Johan Sambre, Didier M Lambert, Filip De Vo. Synthesis, in vitro and in vivo evaluation, and radiolabeling of aryl anandamide analogues as candidate radioligands for in vivo imaging of fatty acid amide hydrolase in the brain. Journal of medicinal chemistry. vol 52. issue 15. 2009-09-21. PMID:19719235. |
compounds 17 and 18 did not display significant binding to cb1 and cb2 cannabinoid receptors and stand out as potential candidate metabolic trapping tracers. |
2009-09-21 |
2023-08-12 |
mouse |
Onintza Sagredo, Sara González, Ilia Aroyo, María Ruth Pazos, Cristina Benito, Isabel Lastres-Becker, Juan P Romero, Rosa M Tolón, Raphael Mechoulam, Emmanuel Brouillet, Julián Romero, Javier Fernández-Rui. Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease. Glia. vol 57. issue 11. 2009-09-14. PMID:19115380. |
cannabinoid cb2 receptor agonists protect the striatum against malonate toxicity: relevance for huntington's disease. |
2009-09-14 |
2023-08-12 |
mouse |
Lin Chen, Jing Zhang, Fan Li, Yue Qiu, Lu Wang, Ying-hua Li, Jing Shi, Hui-Lin Pan, Man L. Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats. The journal of pain. vol 10. issue 7. 2009-09-14. PMID:19409856. |
in this report, we determined the effect of electroacupuncture (ea) on the level of anandamide in the skin tissue and the role of cannabinoid cb1 and cb2 receptors in the analgesic effect of ea in an animal model of inflammatory pain. |
2009-09-14 |
2023-08-12 |
rat |
Yan Wei, Xu Wang, Ling Wan. Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells. Molecular vision. vol 15. 2009-09-14. PMID:19547718. |
here we analyzed the expression of and changes in cannabinoid receptors (cb1 and cb2) and one enzyme responsible for endocannabinoid hydrolysis, fatty acid amide hydrolase (faah), in rpe cell oxidative damage process, a cellular model of armd. |
2009-09-14 |
2023-08-12 |
human |
Gianfranco Alpini, Sharon Demorro. Changes in the endocannabinoid system may give insight into new and effective treatments for cancer. Vitamins and hormones. vol 81. 2009-09-10. PMID:19647123. |
the endocannabinoid system comprises specific cannabinoid receptors such as cb1 and cb2, the endogenous ligands (anandamide and 2-arachidonyl glycerol among others) and the proteins responsible for their synthesis and degradation. |
2009-09-10 |
2023-08-12 |
Not clear |
Rupal Pandey, Venkatesh L Hegde, Narendra P Singh, Lorne Hofseth, Uday Singh, Swapan Ray, Mitzi Nagarkatti, Prakash S Nagarkatt. Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis. Vitamins and hormones. vol 81. 2009-09-10. PMID:19647124. |
the induction of cb1 and cb2 cannabinoid receptors during liver injury and the potential involvement of endocannabinoids in the regulation of this process have sparked significant interest in further evaluating the role of cannabinoid systems during hepatic disease. |
2009-09-10 |
2023-08-12 |
Not clear |
Bastien Reux, Tapio Nevalainen, Katri H Raitio, Ari M P Koskine. Synthesis of quinolinyl and isoquinolinyl phenyl ketones as novel agonists for the cannabinoid CB2 receptor. Bioorganic & medicinal chemistry. vol 17. issue 13. 2009-09-09. PMID:19477133. |
synthesis of quinolinyl and isoquinolinyl phenyl ketones as novel agonists for the cannabinoid cb2 receptor. |
2009-09-09 |
2023-08-12 |
Not clear |
Ruben Nogueiras, Adenis Diaz-Arteaga, Sarah H Lockie, Douglas A Velásquez, Johannes Tschop, Miguel López, Charles C Cadwell, Carlos Diéguez, Matthias H Tschö. The endocannabinoid system: role in glucose and energy metabolism. Pharmacological research. vol 60. issue 2. 2009-09-02. PMID:19559361. |
the ecs acts through two cannabinoid receptors: types 1 and 2 (cb1 and cb2). |
2009-09-02 |
2023-08-12 |
Not clear |