Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Karina S MacDowell, Aline Sayd, Borja García-Bueno, Javier R Caso, José L M Madrigal, Juan Carlos Lez. Effects of the antipsychotic paliperidone on stress-induced changes in the endocannabinoid system in rat prefrontal cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 18. issue 6. 2018-04-23. PMID:26987678. |
cannabinoid receptors and endocannabinoids (ecbs) synthesis and degradation enzymes were measured in prefrontal cortex (pfc) samples by rt-pcr and western blot. |
2018-04-23 |
2023-08-13 |
rat |
Lan Sun, Li Min, Hao Zhou, Man Li, Feng Shao, Weiwen Wan. Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats. Behavioural brain research. vol 333. 2018-04-20. PMID:28705472. |
then, the rats were sacrificed and prefrontal cortex (pfc) tissues were separated for high-throughput proteomics analysis and western blot validation. |
2018-04-20 |
2023-08-13 |
rat |
Dongsheng Zhou, Huaxia Liu, Chenli Li, Fangyan Wang, Yaosheng Shi, Lingjiang Liu, Xin Zhao, Aiming Liu, Junfang Zhang, Chuang Wang, Zhongming Che. Atorvastatin ameliorates cognitive impairment, Aβ1-42 production and Tau hyperphosphorylation in APP/PS1 transgenic mice. Metabolic brain disease. vol 31. issue 3. 2018-01-12. PMID:26883430. |
on the memory deficit by behavioral tests and changes of akt/gsk3β signaling in hippocampus and prefrontal cortex by western blot test in tg app/ps1 mice. |
2018-01-12 |
2023-08-13 |
mouse |
Qian Zhe, Wang Sulei, Tao Weiwei, Long Hongyan, Wang Jianwe. Effects of Jiaotaiwan on depressive-like behavior in mice after lipopolysaccharide administration. Metabolic brain disease. vol 32. issue 2. 2018-01-05. PMID:27796565. |
the protein expressions of nf-κb signaling in prefrontal cortex were determined by western blot. |
2018-01-05 |
2023-08-13 |
mouse |
Lu Li, Chuchu Qiao, Gang Chen, Hongyan Qian, Ying Hou, Tao Li, Xinshe Li. Ifenprodil attenuates the acquisition and expression of methamphetamine-induced behavioral sensitization and activation of Ras-ERK1/2 cascade in the caudate putamen. Neuroscience. vol 335. 2017-12-21. PMID:27544406. |
then, using western blot, ras, perk1/2/erk1/2, and Δfosb levels in the prefrontal cortex (pfc), nucleus accumbens (nac), and caudate putamen (cpu) were detected. |
2017-12-21 |
2023-08-13 |
mouse |
E M Meylan, L Breuillaud, T Seredenina, P J Magistretti, O Halfon, R Luthi-Carter, J-R Cardinau. Involvement of the agmatinergic system in the depressive-like phenotype of the Crtc1 knockout mouse model of depression. Translational psychiatry. vol 6. issue 7. 2017-11-07. PMID:27404284. |
quantitative polymerase chain reaction and western blot analyses confirmed agmat upregulation in the crtc1(-/-) prefrontal cortex (pfc) and hippocampus, which were further demonstrated by confocal immunofluorescence microscopy to comprise an increased number of agmat-expressing cells, notably parvalbumin- and somatostatin-positive interneurons. |
2017-11-07 |
2023-08-13 |
mouse |
Wei Yin, Kevin Clare, Qiujia Zhang, Nora D Volkow, Congwu D. Chronic cocaine induces HIF-VEGF pathway activation along with angiogenesis in the brain. PloS one. vol 12. issue 4. 2017-09-06. PMID:28448515. |
for this purpose we measured nitric oxide (no) concentration in plasma, brain neuronal nitric oxide synthase (nnos or nos1), hif-1α, and vegf expression in different brain regions, i.e., middle prefrontal cortex, somatosensory cortex, nucleus accumbens, and dorsal striatum, using elisa or western blot. |
2017-09-06 |
2023-08-13 |
rat |
Vivian B Neis, Luis E B Bettio, Morgana Moretti, Priscila B Rosa, Camille M Ribeiro, Andiara E Freitas, Filipe M Gonçalves, Rodrigo B Leal, Ana Lúcia S Rodrigue. Acute agmatine administration, similar to ketamine, reverses depressive-like behavior induced by chronic unpredictable stress in mice. Pharmacology, biochemistry, and behavior. vol 150-151. 2017-08-31. PMID:27743829. |
western blot analyses of prefrontal cortex (pfc) demonstrated that mice exposed to cus and/or treated with agmatine, fluoxetine or ketamine did not present alterations in the immunocontent of synaptic proteins [i.e. |
2017-08-31 |
2023-08-13 |
mouse |
Hwayoung Lee, Hansol Won, Jiyun Im, Young Ock Kim, Sanghyun Lee, Ik-Hyun Cho, Hyung-Ki Kim, Jun-Tack Kwon, Hak-Jae Ki. Effect of Valeriana fauriei extract on the offspring of adult rats exposed to prenatal stress. International journal of molecular medicine. vol 38. issue 1. 2017-03-06. PMID:27220809. |
western blot and immunohistochemical analyses of the prefrontal cortex revealed that the downregulation of several neurodevelopmental proteins in the offspring of rats dams exposed to pns was reversed after treatment with vf extract. |
2017-03-06 |
2023-08-13 |
rat |
Ali Siahposht-Khachaki, Zahra Fatahi, Asal Yans, Fariba Khodagholi, Abbas Haghparas. Involvement of AMPA/Kainate Glutamate Receptor in the Extinction and Reinstatement of Morphine-Induced Conditioned Place Preference: A Behavioral and Molecular Study. Cellular and molecular neurobiology. vol 37. issue 2. 2017-02-23. PMID:27053349. |
after behavioral test recording, we dissected out the nac, hip, and pfc regions and measured the p-creb/creb ratio and c-fos level by western blot analysis. |
2017-02-23 |
2023-08-13 |
rat |
Jing Li, Yixin Wang, Fangfang Fang, Donglong Chen, Yue Gao, Jingli Liu, Rong Gao, Jun Wang, Hang Xia. Bisphenol A disrupts glucose transport and neurophysiological role of IR/IRS/AKT/GSK3β axis in the brain of male mice. Environmental toxicology and pharmacology. vol 43. 2017-02-09. PMID:26923231. |
mice were treated with subcutaneous injection of 100μg/kg/d bpa or vehicle for 30 days, then the insulin signaling and glucose transporters in the hippocampus and prefrontal cortex were detected by western blot. |
2017-02-09 |
2023-08-13 |
mouse |
Ziye Wang, Wenwen Li, Jin Chen, Haiyang Shi, Mingjun Zhao, Hongmin You, Chenglong Rao, Yuan Zhan, Yongtao Yang, Peng Xi. Proteomic analysis reveals energy metabolic dysfunction and neurogenesis in the prefrontal cortex of a lipopolysaccharide-induced mouse model of depression. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26718926. |
a total of 26 differentially expressed proteins were identified, two of which were selected for western blot analysis, the results of which revealed a significant increase in the expression levels of creatine kinase b and dihydropyrimidinase-like 3 in dep mice, suggesting that changes in energy metabolism and neuro-genesis occur in the pfc of dep mice. |
2016-10-31 |
2023-08-13 |
mouse |
Zachary S Bailey, Michael B Grinter, Pamela J VandeVor. Astrocyte Reactivity Following Blast Exposure Involves Aberrant Histone Acetylation. Frontiers in molecular neuroscience. vol 9. 2016-08-23. PMID:27551260. |
western blot analysis showed glial fibrillary acidic protein (gfap), a known marker of activated astrocytes, was elevated in the prefrontal cortex (pfc) following blast exposure for both injury groups. |
2016-08-23 |
2023-08-13 |
rat |
Zhen Feng, Qing D. Mechanisms responsible for the effect of median nerve electrical stimulation on traumatic brain injury-induced coma: orexin-A-mediated N-methyl-D-aspartate receptor subunit NR1 upregulation. Neural regeneration research. vol 11. issue 6. 2016-08-02. PMID:27482224. |
to further understand the mechanism underlying wakefulness mediated by electrical stimulation of the median nerve, we evaluated its effects on the expression of the n-methyl-d-aspartate receptor subunit nr1 in the prefrontal cortex in rat models of traumatic brain injury-induced coma, using immunohistochemistry and western blot assays. |
2016-08-02 |
2023-08-13 |
rat |
Q Ren, M Ma, C Yang, J-C Zhang, W Yao, K Hashimot. BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms. Translational psychiatry. vol 5. 2016-07-19. PMID:26506052. |
western blot analysis showed that bdnf levels in the nucleus accumbens (nac) of meth-treated mice were significantly higher than those of control mice whereas bdnf levels in other regions, including the prefrontal cortex and hippocampus, were not altered. |
2016-07-19 |
2023-08-13 |
mouse |
Rubén García-Cabrerizo, M Julia García-Fuste. Opposite regulation of cannabinoid CB1 and CB2 receptors in the prefrontal cortex of rats treated with cocaine during adolescence. Neuroscience letters. vol 615. 2016-07-14. PMID:26797579. |
this study evaluated cb1 and cb2 protein levels in prefrontal cortex (pfc) and hippocampus (hc) by western blot analysis with specific and validated antibodies: (1) basally during adolescence (post-natal day pnd 40, pnd 47, pnd 54), (2) by a sensitizing regimen of cocaine (15mg/kg, 7 days, i.p.) |
2016-07-14 |
2023-08-13 |
rat |
Jordyn M Kippe, Toni M Mueller, Vahram Haroutunian, James H Meador-Woodruf. Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia. Schizophrenia research. vol 166. issue 1-3. 2016-05-02. PMID:26104473. |
we measured protein expression of nine distinct glcnacts by western blot analysis in postmortem samples of dorsolateral prefrontal cortex (dlpfc) from twelve pairs of elderly patients with schizophrenia and comparison subjects. |
2016-05-02 |
2023-08-13 |
human |
Courtney R Sullivan, Adam J Funk, Dan Shan, Vahram Haroutunian, Robert E McCullumsmit. Decreased chloride channel expression in the dorsolateral prefrontal cortex in schizophrenia. PloS one. vol 10. issue 3. 2016-03-29. PMID:25826365. |
in this study, we performed western blot analysis to investigate whether the na-k-cl and k-cl cotransporter protein is abnormally expressed in the dorsal lateral prefrontal cortex and the anterior cingulate cortex in patients with schizophrenia versus a control group. |
2016-03-29 |
2023-08-13 |
human |
Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters. vol 606. 2016-03-01. PMID:26300543. |
levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-κb (nf-κb) in hippocampal was determined by western blot analysis. |
2016-03-01 |
2023-08-13 |
mouse |
Murui Han, Jonghan Ki. Effect of dietary iron loading on recognition memory in growing rats. PloS one. vol 10. issue 3. 2016-01-25. PMID:25746420. |
western blot analysis showed an up-regulation of dopamine receptor 1 in the prefrontal cortex from iron-loaded rats (142% increase; p=0.002). |
2016-01-25 |
2023-08-13 |
rat |