| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuping Luo, Bo Zhou, Fen Liu, Rong Ai, Min Wen, Xuetao Ton. [Enhanced autophagy activates p38/MEF2C pathway to regulate the expression of synapse-associated proteins and improve the symptoms of autistic rats]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 35. issue 3. 2019-08-15. PMID:31030717. |
western blot analysis was used to detect the protein levels of p38, phosphorylated p38 (p-p38), mef2c, synaptic vesicle protein (syn), postsynaptic density 95 (psd-95), and gephyrin protein in the prefrontal cortex of rats; immunohistochemical staining was used to detect the expression and distribution of syn, psd-95 and gephyrin in the prefrontal cortex, and semi-quantitative analysis was performed then. |
2019-08-15 |
2023-08-13 |
rat |
| Wenqi Gao, Wei Wang, Yan Peng, Zhifang Den. Antidepressive effects of kaempferol mediated by reduction of oxidative stress, proinflammatory cytokines and up-regulation of AKT/β-catenin cascade. Metabolic brain disease. vol 34. issue 2. 2019-08-13. PMID:30762138. |
furthermore, activity level of akt/β-catenin signaling in the prefrontal cortex of csds mice was investigated by western blot. |
2019-08-13 |
2023-08-13 |
mouse |
| C E M Fernandes, K R Serafim, A C L Gianlorenço, R Mattiol. Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 52. issue 5. 2019-07-26. PMID:31038580. |
the results obtained using western blot analysis demonstrated that vuf-8430 induced a decrease in creb and pcreb levels in the cerebellar vermis and prefrontal cortex, suggesting that this dose impaired the activation of cell signaling pathways in these structures. |
2019-07-26 |
2023-08-13 |
mouse |
| Cleciane Waldetário Martins, Lívia Carla de Melo Rodrigues, Michael A Nitsche, Ester Miyuki Nakamura-Palacio. AMPA receptors are involved in prefrontal direct current stimulation effects on long-term working memory and GAP-43 expression. Behavioural brain research. vol 362. 2019-07-11. PMID:30654123. |
the prefrontal cortex (pfc) and hippocampus (hpc) were removed 24-h later and gap-43 (growth-associated protein) expression was measured by western blot analysis. |
2019-07-11 |
2023-08-13 |
rat |
| Panchanan Maiti, Leela Paladugu, Gary L Dunba. Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer's disease. BMC neuroscience. vol 19. issue 1. 2019-05-16. PMID:29471781. |
levels of aβ aggregation, including oligomers and fibril formation, were assessed by dot blot assay, while aβ plaque load and neuronal morphology in the pre-frontal cortex (pfc) and hippocampus were assayed by immunolabeling with aβ-specific antibody and cresyl violet staining, respectively. |
2019-05-16 |
2023-08-13 |
mouse |
| Sami Alzarea, Shafiqur Rahma. Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 86. 2019-04-15. PMID:29800595. |
we also examined the effects of pnu 120596 on iba-1 expression by using western blot analysis and immunofluorescence staining in the hippocampus and prefrontal cortex, the brain regions implicated in major depressive disorder. |
2019-04-15 |
2023-08-13 |
mouse |
| Shaokang Dang, Yong Lu, Qian Su, Tianwei Lin, Xiaoxiao Zhang, Huiping Zhang, Junli Zhang, Lin Zhang, Zhongliang Zhu, Hui L. H3K9 Acetylation of Tph2 Involved in Depression-like Behavior in Male, but not Female, Juvenile Offspring Rat Induced by Prenatal Stress. Neuroscience. vol 381. 2019-04-05. PMID:29625215. |
the mrna and protein expression levels of tph2 in the dorsal raphenucleus (drn), hippocampus, and prefrontal cortex were detected with quantitative real-time pcr and western blot analysis, respectively. |
2019-04-05 |
2023-08-13 |
rat |
| Marina Zaric, Dunja Drakulic, Ivana Gusevac Stojanovic, Natasa Mitrovic, Ivana Grkovic, Jelena Martinovi. Regional-specific effects of cerebral ischemia/reperfusion and dehydroepiandrosterone on synaptic NMDAR/PSD-95 complex in male Wistar rats. Brain research. vol 1688. 2019-04-01. PMID:29577884. |
western blot was used for analyses of synaptic protein expressions in hippocampus and prefrontal cortex, while neuronal morphology was assessed using nissl staining. |
2019-04-01 |
2023-08-13 |
rat |
| Zahra Ghasemzadeh, Ameneh Rezayo. Medial Prefrontal Cortical Cannabinoid CB1 Receptors Mediate Morphine-Dextromethorphan Cross State-Dependent Memory: The Involvement of BDNF/cFOS Signaling Pathways. Neuroscience. vol 393. 2019-03-07. PMID:30326290. |
changes on the levels of bdnf and cfos proteins in the pfc were examined by western blot analysis. |
2019-03-07 |
2023-08-13 |
rat |
| Shuai Yuan, Xiaofeng Jiang, Xinyu Zhou, Yuqing Zhang, Teng Teng, Peng Xi. Inosine alleviates depression-like behavior and increases the activity of the ERK-CREB signaling in adolescent male rats. Neuroreport. vol 29. issue 14. 2019-02-27. PMID:30028377. |
changes in the extracellular signal-regulated kinases (erk)-cyclic amp response element binding protein (creb) signaling pathway in the hippocampus and prefrontal cortex were examined by western blot analysis. |
2019-02-27 |
2023-08-13 |
rat |
| Suku-Maran Shalini, Christabel Fung-Yih Ho, Yee-Kong Ng, Jie-Xin Tong, Eng-Shi Ong, Deron R Herr, Gavin S Dawe, Wei-Yi On. Distribution of Alox15 in the Rat Brain and Its Role in Prefrontal Cortical Resolvin D1 Formation and Spatial Working Memory. Molecular neurobiology. vol 55. issue 2. 2018-12-21. PMID:28181190. |
western blot analysis was consistent with rt-pcr data, in that the prefrontal cortex, cerebral cortex, hippocampus, and olfactory bulb had high alox15 protein expression. |
2018-12-21 |
2023-08-13 |
rat |
| Gabriela Riego, Alejandro Redondo, Sergi Leánez, Olga Po. Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain. Biochemical pharmacology. vol 148. 2018-12-17. PMID:29247614. |
in male c57bl6 mice with neuropathic pain induced by the chronic constriction of sciatic nerve (cci), we evaluated the effects of corm-2 and copp on the expression of the nuclear factor erythroid 2-related factor 2 (nrf2), ho-1 and nad(p)h:quinone oxidoreductase-1 (nqo1), the microglial marker (cd11b/c), and the mitogen-activated protein kinases (mapk) (jnk, erk½ and p38) in the amygdala, prefrontal cortex, hippocampus, hypothalamus and spinal cord, by using western blot assay. |
2018-12-17 |
2023-08-13 |
mouse |
| Marissa Giovanna Schamne, Josiel Mileno Mack, Morgana Moretti, Filipe Carvalho Matheus, Roger Walz, Laurence Lanfumey, Rui Daniel Predige. The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors. Neurotoxicity research. vol 34. issue 4. 2018-11-26. PMID:29808370. |
we also investigated the immunocontent of neurotrophins (bdnf, gdnf, and vegf) in the hippocampus and prefrontal cortex by western blot. |
2018-11-26 |
2023-08-13 |
mouse |
| E H Chang, K Fernando, L W E Yeung, K Barbari, T-S S Chandon, A K Malhotr. Single point mutation on the gene encoding dysbindin results in recognition deficits. Genes, brain, and behavior. vol 17. issue 5. 2018-10-30. PMID:29227583. |
by western blot analysis, we found that spp homozygous (spp -/-) mutants had reduced dysbindin and synaptosomal-associated protein 25 (snap-25) in the prefrontal cortex, but unaltered levels in hippocampus. |
2018-10-30 |
2023-08-13 |
mouse |
| Ke-Ke Jia, Shu-Man Pan, Hong Ding, Jia-Hui Liu, Yan-Jing Zheng, Shui-Juan Wang, Ying Pan, Ling-Dong Kon. Chaihu-shugan san inhibits inflammatory response to improve insulin signaling in liver and prefrontal cortex of CUMS rats with glucose intolerance. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-11. PMID:29864926. |
western blot was used to detect the expression of key proteins in inflammatory signaling cascades including toll-like receptor 4 (tlr4), myeloid differentiation protein 88 (myd88), nuclear factor-kappa b (nf-κb), nod-like receptor family pyrin domain containing 3 (nlrp3), apoptosis-associated speck-like protein containing card (asc), cysteinyl aspartate specific proteinase-1 (caspase-1) and il-1β, as well as insulin signaling in liver and prefrontal cortex of rats. |
2018-10-11 |
2023-08-13 |
rat |
| Ke-Ke Jia, Shu-Man Pan, Hong Ding, Jia-Hui Liu, Yan-Jing Zheng, Shui-Juan Wang, Ying Pan, Ling-Dong Kon. Chaihu-shugan san inhibits inflammatory response to improve insulin signaling in liver and prefrontal cortex of CUMS rats with glucose intolerance. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-10-11. PMID:29864926. |
immunohistochemical staining or immunofluorescence staining of nf-κb, and nuclear/cytoplasmic ratio of nf-κb by western blot were used to describe its nuclear entry in liver and prefrontal cortex of rats. |
2018-10-11 |
2023-08-13 |
rat |
| Shuiqiao Liu, Qingqing Dai, Rongrong Hua, Ting Liu, Song Han, Shujuan Li, Junfa L. Determination of Brain-Regional Blood Perfusion and Endogenous cPKCγ Impact on Ischemic Vulnerability of Mice with Global Ischemia. Neurochemical research. vol 42. issue 10. 2018-08-07. PMID:28597398. |
nissl staining and western blot results indicated that hypothalamus and midbrain had more severe neural cell loss than prefrontal cortex, striatum and hippocampus, which negatively coincided with endogenous cpkcγ protein levels but not blood perfusion loss and cpkcγ membrane translocation levels. |
2018-08-07 |
2023-08-13 |
mouse |
| Octavio Amancio-Belmont, Antonio Romano-López, Alejandra Evelin Ruiz-Contreras, Mónica Méndez-Díaz, Oscar Prospéro-Garcí. From adolescent to elder rats: Motivation for palatable food and cannabinoids receptors. Developmental neurobiology. vol 77. issue 8. 2018-05-22. PMID:27935269. |
in addition, cb1 and cb2 receptor expression in the nucleus accumbens (nacc) and prefrontal cortex (pfc) was estimated by means of western blot. |
2018-05-22 |
2023-08-13 |
human |
| Octavio Amancio-Belmont, Diego Pérez-Vázquez, Alejandra E Ruiz-Contreras, Miguel Pérez de la Mora, Pavel E Rueda-Orozco, Mónica Méndez-Díaz, Oscar E Prospero-Garci. Chloramphenicol decreases CB1 receptor expression in the nucleus accumbens and prefrontal cortex and prevents amphetamine-induced conditioned place preference in rats. Pharmacology, biochemistry, and behavior. vol 159. 2018-05-21. PMID:28642068. |
once cpp was evaluated rats were sacrificed and the prefrontal cortex (pfc), the nucleus accumbens (nacc) and the hippocampus (hipp) were isolated and prepared for cb1r western blot analysis. |
2018-05-21 |
2023-08-13 |
rat |
| Karina S MacDowell, Aline Sayd, Borja García-Bueno, Javier R Caso, José L M Madrigal, Juan Carlos Lez. Effects of the antipsychotic paliperidone on stress-induced changes in the endocannabinoid system in rat prefrontal cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 18. issue 6. 2018-04-23. PMID:26987678. |
cannabinoid receptors and endocannabinoids (ecbs) synthesis and degradation enzymes were measured in prefrontal cortex (pfc) samples by rt-pcr and western blot. |
2018-04-23 |
2023-08-13 |
rat |