All Relations between blot and prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Josephine R Tarren, Henry A Lester, Arnauld Belmer, Selena E Bartlet. Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala. Frontiers in molecular neuroscience. vol 10. 2020-09-30. PMID:29114204. in the present study, we measured the effect of acute binge ethanol on nachr α4 subunit levels in the prefrontal cortex (pfc), nucleus accumbens (nac), ventral tegmental area (vta), and amygdala (amg) by western blot analysis using a knock-in mouse line, generated with a normally functioning α4 nachr subunit tagged with yellow fluorescent protein (yfp). 2020-09-30 2023-08-13 mouse
Hui Li, Tong Wang, Cuige Shi, Yutao Yang, Xiaoxiao Li, Yan Wu, Zhi-Qing David X. Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels. Frontiers in psychiatry. vol 9. 2020-09-30. PMID:30487761. moreover, western blot and hplc assays demonstrated that the downregulation of creb-bdnf signaling and 5-ht levels in the pfc of ppd rats were reversed after galr1-sirna injection. 2020-09-30 2023-08-13 rat
Jun-Jie Wang, Jun-De Zhu, Xian-Hu Zhang, Ting-Ting Long, Guo Ge, Yan Y. Neuroprotective effect of Notch pathway inhibitor DAPT against focal cerebral ischemia/reperfusion 3 hours before model establishment. Neural regeneration research. vol 14. issue 3. 2020-09-30. PMID:30539813. protein expression levels of hes1 and hes5 were detected by western blot assay in the right prefrontal cortex. 2020-09-30 2023-08-13 mouse
Yun-Kai Xie, Xin Zhou, Hong-Tao Yuan, Jie Qiu, Dan-Qing Xin, Xi-Li Chu, Da-Chuan Wang, Zhen Wan. Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress. Neural regeneration research. vol 14. issue 10. 2020-09-28. PMID:31169191. western blot assay was utilized to analyze the expression levels of nuclear factor-erythroid 2-related factor 2, heme oxygenase 1, glucose-regulated protein 78 and chop protein expression levels in the prefrontal cortex. 2020-09-28 2023-08-13 rat
Ke Fang, Hua-Rong Li, Xing-Xing Chen, Xin-Ran Gao, Ling-Ling Huang, An-Qi Du, Chuan Jiang, Hua Li, Jin-Fang G. Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009956. results of western blot showed that the expression levels of bdnf, copine 6, p-trkb, and the triggering receptors expressed on myeloid cells (trem) 1 were decreased in both the hippocampus and the prefrontal cortex (pfc) of lps-challenged rats, while the expression of trem2 was increased. 2020-09-28 2023-08-13 mouse
Cheng-Bo-Wen Zhao, Jie Liu, Jin-Li Shi, Shao-Nan Wang, Yong-Sheng Ding, Shuai He, Ming-Xuan Lin, Jing Luo, Yi-Nan Jiang, Li-Hua Bian, Zi-Wei Yao, Qiu-Yu Li, Xiao-Mei Wang, Jian-You Gu. Anxiolytic Effect of Alcohol-Water Extracted Suanzaoren-Wuweizi Herb-Pair by Regulating ECS-BDNF-ERK Signaling Pathway Expression in Acute Restraint Stress Male Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-09-28. PMID:32655658. the concentration of bndf, erk1/2, p-erk1/2, camp-response element binding protein (creb), and p-creb expression in the prefrontal cortex and hippocampus of the rats was then measured by western blot. 2020-09-28 2023-08-13 rat
Lulu Xie, Zhimin Gu, Haizhao Liu, Beitian Jia, Yiyang Wang, Min Cao, Ruiwen Song, Zhaiyi Zhang, Yuhong Bia. The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32922291. pcr and western blot were used to monitor the differences of nlrp3, caspase-1, asc activation in the levels of genes and proteins in the pfc of rats and microglia. 2020-09-28 2023-08-13 rat
Emilia Metryka, Izabela Gutowska, Patrycja Kupnicka, Maciej Tarnowski, Marta Tkacz, Joanna Listos, Sylwia Talarek, Katarzyna Barczak, Dariusz Chlubek, Irena Baranowska-Bosiack. ‬The expression of purinergic P2X4 and P2X7 receptors in selected mesolimbic structures during morphine withdrawal in rats. Brain research. vol 1719. 2020-09-25. PMID:31121160. in the present study the mrna and protein expression of purinergic p2x4 and p2x7 receptors in selected mesolimbic structures (striatum, hippocampus and prefrontal cortex) during morphine withdrawal in rats was investigated by rt-pcr and western blot analysis. 2020-09-25 2023-08-13 rat
Si-Yu Lin, Jun Ma, Jian-Xiong An, Xiao-Yan Qian, Yong Wang, Doris K Cope, John P William. Ozone Inhibits APP/Aβ Production and Improves Cognition in an APP/PS1 Transgenic Mouse Model. Neuroscience. vol 418. 2020-09-24. PMID:31349006. prefrontal cortex and hippocampus amyloid-β precursor protein (app), along with other relevant biomarkers for ad, were measured through elisa, western blot and immunohistochemistry. 2020-09-24 2023-08-13 mouse
Zongbo Sun, Ye Ma, Lei Xie, Jinzhuang Huang, Shouxing Duan, Ruiwei Guo, Yao Xie, Junyao Lv, Zhirong Lin, Shuhua M. Behavioral Changes and Neuronal Damage in Rhesus Monkeys after 10 Weeks of Ketamine Administration Involve Prefrontal Cortex Dopamine D2 Receptor and Dopamine Transporter. Neuroscience. vol 415. 2020-09-23. PMID:31330230. additionally, neuronal changes in the pfc were examined by hematoxylin and eosin (he) staining; the drd2 and dat mrna and protein expression levels in the pfc were determined by real-time pcr and western blot analysis, respectively. 2020-09-23 2023-08-13 monkey
Musaad A Alshammari, Mohammad R Khan, Fawaz Alasmari, Abdulaziz O Alshehri, Rizwan Ali, Mohamed Boudjelal, Khalid A Alhosaini, Abdurahman A Niazy, Tahani K Alshammar. Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model. Neural plasticity. vol 2019. 2020-09-15. PMID:31933626. using western blot studies and high-resolution confocal microscopy in the prefrontal frontal cortex (pfc), our data indicate disrupted expression of different isoforms of the voltage-gated sodium channels (nav) at the ais, whereas other components of ais such as ankyrin-g and fibroblast growth factor 14 (fgf14) and contactin-associated protein 1 (caspr) in btbr were comparable to those in wild-type control mice. 2020-09-15 2023-08-13 mouse
Musaad A Alshammari, Mohammad R Khan, Fawaz Alasmari, Abdulaziz O Alshehri, Rizwan Ali, Mohamed Boudjelal, Khalid A Alhosaini, Abdurahman A Niazy, Tahani K Alshammar. Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model. Neural plasticity. vol 2019. 2020-09-15. PMID:31933626. a western blot assay showed that btbr mice exhibited a marked increase in different sodium channel isoforms in the pfc compared to wild-type mice. 2020-09-15 2023-08-13 mouse
Ashleigh L Osborne, Nadia Solowij, Ilijana Babic, Jeremy S Lum, Kelly A Newell, Xu-Feng Huang, Katrina Weston-Gree. Effect of cannabidiol on endocannabinoid, glutamatergic and GABAergic signalling markers in male offspring of a maternal immune activation (poly I:C) model relevant to schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 95. 2020-08-26. PMID:31202911. the prefrontal cortex (pfc) and hippocampus (hpc) were collected for post-mortem receptor binding and western blot analyses (n = 8 per group). 2020-08-26 2023-08-13 rat
Courtney R Sullivan, Rachael H Koene, Kathryn Hasselfeld, Sinead M O'Donovan, Amy Ramsey, Robert E McCullumsmit. Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia. Molecular psychiatry. vol 24. issue 9. 2020-04-27. PMID:29497148. we examined bioenergetic pathways in the dorsolateral prefrontal cortex (dlpfc) of subjects with schizophrenia and control subjects using western blot analysis, quantitative real-time polymerase chain reaction, and enzyme/substrate assays. 2020-04-27 2023-08-13 human
Zhongwei Xiong, Kai Zhang, Tamaki Ishima, Qian Ren, Min Ma, Yaoyu Pu, Lijia Chang, Jincao Chen, Kenji Hashimot. Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine. Pharmacology, biochemistry, and behavior. vol 176. 2020-02-25. PMID:30502360. western blot analysis of kir4.1 protein in the brain regions (prefrontal cortex, nucleus accumbens, hippocampus) from csds susceptible mice and control mice (no csds) was performed. 2020-02-25 2023-08-13 mouse
Haixia Yuan, Xinqiang Ni, Min Zheng, Xinmin Han, Yuchen Song, Minfeng Y. Effect of catalpol on behavior and neurodevelopment in an ADHD rat model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 118. 2020-02-13. PMID:31545235. finally, western blot and immunostaining analysis suggested that several regulatory proteins involved in pfc development were up-regulated by catalpol treatment, such as brain-derived neurotrophic factor (bdnf), cyclin-dependent kinase 5 (cdk5), p35, fibroblast growth factor (fgf) 21 and its receptor (fgfr)1. 2020-02-13 2023-08-13 rat
Ghanshyam N Pandey, Hooriyah S Rizavi, Runa Bhaumik, Xinguo Re. Innate immunity in the postmortem brain of depressed and suicide subjects: Role of Toll-like receptors. Brain, behavior, and immunity. vol 75. 2020-01-23. PMID:30266463. we determined the protein expression by western blot and mrna expression levels by real-time pcr (qpcr) in the pfc of 24 nc, 24 ds, 12 dns and 11 nds subjects. 2020-01-23 2023-08-13 human
Farnaz Karimani, Ladan Delphi, Ameneh Rezayo. Nitric oxide blockade in mediodorsal thalamus impaired nicotine/ethanol-induced memory retrieval in rats via inhibition of prefrontal cortical pCREB/CREB signaling pathway. Neurobiology of learning and memory. vol 162. 2019-12-27. PMID:31047996. subsequently, western blot analysis was used to evaluate how this change would alter the pfc pcreb/creb signaling pathway. 2019-12-27 2023-08-13 rat
Meng-Meng Li, Ping Zhou, Xiao-Dong Chen, Huai-Sha Xu, Jun Wang, Ling Chen, Ning Zhang, Na Li. NO in the dPAG modulates panic-like responses and ASIC1a expression in the prefrontal cortex and hippocampus in mice. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-23. PMID:30770101. in our study, c57bl/6 mice received an intra-dpag injection of snap or 7-ni before ret; neurobehavioral tests were then conducted, followed by mechanistic evaluation through western blot analysis in the pfc and hippocampus. 2019-12-23 2023-08-13 mouse
Yuping Luo, Bo Zhou, Fen Liu, Rong Ai, Min Wen, Xuetao Ton. [Enhanced autophagy activates p38/MEF2C pathway to regulate the expression of synapse-associated proteins and improve the symptoms of autistic rats]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 35. issue 3. 2019-08-15. PMID:31030717. western blot analysis was used to detect the protein levels of p38, phosphorylated p38 (p-p38), mef2c, synaptic vesicle protein (syn), postsynaptic density 95 (psd-95), and gephyrin protein in the prefrontal cortex of rats; immunohistochemical staining was used to detect the expression and distribution of syn, psd-95 and gephyrin in the prefrontal cortex, and semi-quantitative analysis was performed then. 2019-08-15 2023-08-13 rat