| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jun Lu, Jia Liang, Jun-Ren Wang, Li Hu, Ya Tu, Jian-You Gu. Acupuncture Activates ERK-CREB Pathway in Rats Exposed to Chronic Unpredictable Mild Stress. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-07-11. PMID:23843874. |
the protein levels of erk1/2, creb, phosphorylated erk1/2 (p-erk1/2), and phosphorylated creb (p-creb) in the hippocampus (hp) and prefrontal cortex (pfc) were examined by western blot analysis. |
2013-07-11 |
2023-08-12 |
rat |
| Shuichi Chiba, Tadahiro Numakawa, Midori Ninomiya, Misty C Richards, Chisato Wakabayashi, Hiroshi Kunug. Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:22664354. |
when the pfc was removed after crs and subject to western blot analysis, the gr expression reduced compared with control, while the levels of bdnf and its receptors remained unchanged. |
2013-01-21 |
2023-08-12 |
human |
| Jia Qi, Wen-Yan Han, Jing-Yu Yang, Li-Hui Wang, Ying-Xu Dong, Fang Wang, Ming Song, Chun-Fu W. Oxytocin regulates changes of extracellular glutamate and GABA levels induced by methamphetamine in the mouse brain. Addiction biology. vol 17. issue 4. 2012-10-01. PMID:22507692. |
western blot results indicated that ot significantly inhibited the increased glutamatergic receptor (nr1 subunit) levels in the pfc after acute map administration, whereas ot further enhanced the elevated levels of glutamatergic transporter (glt1) induced by map in the hippocampus of mice. |
2012-10-01 |
2023-08-12 |
mouse |
| Gwendolen E Haley, Dominique H Eghlidi, Steven G Kohama, Henryk F Urbanski, Jacob Rabe. Association of microtubule associated protein-2, synaptophysin, and apolipoprotein E mRNA and protein levels with cognition and anxiety levels in aged female rhesus macaques. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22475553. |
map2, syn, and apoe mrna and protein levels in the prefrontal cortex (pfc), hippocampus, and amygdala, were assessed using qrt-pcr and western blot. |
2012-09-27 |
2023-08-12 |
monkey |
| Fafeng Cheng, Xianggen Zhong, Yi Lu, Xueqian Wang, Wenting Song, Shaoying Guo, Xiaotong Wang, Dantong Liu, Qingguo Wan. Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-08-23. PMID:22536287. |
neurological function and brain infarction were examined and cell apoptosis and ros at prefrontal cortex were evaluated 24 h after mcao, and western blot and intracellular calcium were also researched, respectively. |
2012-08-23 |
2023-08-12 |
mouse |
| Carmela M Reichel, Lauren A Ramsey, Marek Schwendt, Jacqueline F McGinty, Ronald E Se. Methamphetamine-induced changes in the object recognition memory circuit. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22115899. |
subsequently, transporters for serotonin (sert) and norepinephrine (net) were quantified using western blot in tissue obtained from the hippocampus, perirhinal cortex, and prefrontal cortex. |
2012-07-27 |
2023-08-12 |
human |
| Jeeva Varadarajulu, Andrea Schmitt, Peter Falkai, Murtada Alsaif, Christoph W Turck, Daniel Martins-de-Souz. Differential expression of HINT1 in schizophrenia brain tissue. European archives of psychiatry and clinical neuroscience. vol 262. issue 2. 2012-07-16. PMID:21553311. |
using western blot, we compared hint1 protein expression in the postmortem dorsolateral prefrontal cortex and thalamus of schizophrenia patients and healthy controls for contributing to elucidate the role of hint1 in schizophrenia pathophysiology. |
2012-07-16 |
2023-08-12 |
human |
| H Y Yang, C P Sun, X M Jia, L Gui, D F Zhu, W Q M. Effect of thyroxine on SNARE complex and synaptotagmin-1 expression in the prefrontal cortex of rats with adult-onset hypothyroidism. Journal of endocrinological investigation. vol 35. issue 3. 2012-07-10. PMID:21646859. |
pfc levels of synaptosomal-associated protein of 25 kda (snap-25), syntaxin-1, vesicle-associated membrane protein 2 (vamp-2) and syt-1 were determined by immunohistochemistry and western blot analyses. |
2012-07-10 |
2023-08-12 |
rat |
| Kwankanit Sae-Ung, Kenji Uéda, Piyarat Govitrapong, Pansiri Phansuwan-Pujit. Melatonin reduces the expression of alpha-synuclein in the dopamine containing neuronal regions of amphetamine-treated postnatal rats. Journal of pineal research. vol 52. issue 1. 2012-06-18. PMID:21851386. |
as determined using western blot, the level of α-syn was significantly increased in the substantia nigra, dorsal striatum, nucleus accumbens, and prefrontal cortex of the amph-treated group, while melatonin treatment either prior to amph or alone decreased the accumulation of the protein to 77%, 96%, 78%, and 77% of the control value, respectively. |
2012-06-18 |
2023-08-12 |
rat |
| Teresa Ponce-Lopez, Gustavo Liy-Salmeron, Enrique Hong, Alfredo Menese. Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model. Brain research. vol 1426. 2012-03-05. PMID:22036080. |
the enzymes were measured in the hippocampus and prefrontal cortex (pfc) by western blot. |
2012-03-05 |
2023-08-12 |
human |
| Courtney S Jernigan, Dharmendra B Goswami, Mark C Austin, Abiye H Iyo, Agata Chandran, Craig A Stockmeier, Beata Karolewic. The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 7. 2012-02-08. PMID:21635931. |
in this study, we examined the expression of mtor and its core downstream signaling targets: p70s6k, eif4e, and eif4b in the pfc of 12 depressed subjects and 12 psychiatrically healthy controls using western blot. |
2012-02-08 |
2023-08-12 |
human |
| Abbas Haghparast, Zahra Taslimi, Mahmoudreza Ramin, Pegah Azizi, Farbia Khodagholi, Majid Hassanpour-Ezatt. Changes in phosphorylation of CREB, ERK, and c-fos induction in rat ventral tegmental area, hippocampus and prefrontal cortex after conditioned place preference induced by chemical stimulation of lateral hypothalamus. Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21295078. |
after the acquisition period, the brains were removed, and p-creb and p-erk, and c-fos induction in the ipsilateral vta, hippocampus and pfc were measured by western blot analysis. |
2011-07-15 |
2023-08-12 |
rat |
| A Marzo, J Bai, J Caboche, P Vanhoutte, S Otan. Cellular mechanisms of long-term depression induced by noradrenaline in rat prefrontal neurons. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20434527. |
western blot analyses showed that na (20 microm for 12.5 min) indeed induces transient increases of erk1/2 phosphorylation in pfc neurons, which is dependent at least in part on the activation of nmda receptors and alpha1-adrenoceptors. |
2011-03-04 |
2023-08-12 |
rat |
| Noelle C Anastasio, Maria Fe Lanfranco, Marcy J Bubar, Patricia K Seitz, Sonja J Stutz, Andrew G McGinnis, Cheryl S Watson, Kathryn A Cunningha. Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex. Journal of neurochemistry. vol 113. issue 6. 2010-08-06. PMID:20345755. |
utilizing multiples tissues (brain, peripheral tissues), protein fractions (synaptosomal, post-synaptic density), and controls (peptide neutralization, 5-ht(2c)r stably-expressing cells), we established the selectivity of two commercially available 5-ht(2c)r antibodies and employed the antibodies in western blot and immunoprecipitation studies of prefrontal cortex (pfc) and motor cortex, two regions implicated in cognitive, emotional and motor dysfunction. |
2010-08-06 |
2023-08-12 |
rat |
| Xin Liu, Le Jin Yang, Shu Juan Fan, Hong Jiang, Fang Pa. Swimming exercise effects on the expression of HSP70 and iNOS in hippocampus and prefrontal cortex in combined stress. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20398736. |
the expression of hsp70 and inos in hippocampus and prefrontal cortex was analyzed by western blot. |
2010-07-30 |
2023-08-12 |
rat |
| Rebecca M Shansky, Genevieve Bender, A F T Arnste. Estrogen prevents norepinephrine alpha-2a receptor reversal of stress-induced working memory impairment. Stress (Amsterdam, Netherlands). vol 12. issue 5. 2010-02-12. PMID:19005873. |
western blot analysis for alpha-2 receptors was performed on pfc tissue from each group, but no changes in expression were found, indicating that the behavioral effects observed were likely not due to changes in receptor expression. |
2010-02-12 |
2023-08-12 |
rat |
| Hans-Gert Bernstein, Theresia Ernst, Uwe Lendeckel, Alicja Bukowska, Siegfried Ansorge, Renate Stauch, Sara Ten Have, Johann Steiner, Henrik Dobrowolny, Bernhard Bogert. Reduced neuronal expression of insulin-degrading enzyme in the dorsolateral prefrontal cortex of patients with haloperidol-treated, chronic schizophrenia. Journal of psychiatric research. vol 43. issue 13. 2009-11-09. PMID:19394958. |
in addition, relative concentrations of ide protein in the dorsolateral prefrontal cortex were estimated by western blot analysis. |
2009-11-09 |
2023-08-12 |
rat |
| Q-Y Meng, W Wang, X-N Chen, T-L Xu, J-N Zho. Distribution of acid-sensing ion channel 3 in the rat hypothalamus. Neuroscience. vol 159. issue 3. 2009-09-21. PMID:19356693. |
we thus employed reverse transcription-polymerase chain reaction (rt-pcr) and western blot to examine the expression of asic3 in various rat brain regions, including hippocampus, amygdala, caudate putamen, prefrontal cortex, and hypothalamus. |
2009-09-21 |
2023-08-12 |
rat |
| Quan Li, Xin Zhao, Li-Jun Zhong, Hai-Yu Yang, Qi Wang, Xiao-Ping P. Effects of chronic morphine treatment on protein expression in rat dorsal root ganglia. European journal of pharmacology. vol 612. issue 1-3. 2009-07-09. PMID:19345208. |
aldolase c and proteasome subunit alpha type 3 (prc8 or alpha7) were further examined by western blot analysis in the drg, prefrontal cortex, nucleus accumbens, striatum, hippocampus, ventral tegmental area and locus coeruleus. |
2009-07-09 |
2023-08-12 |
rat |
| Bernadeta Szewczyk, Paul R Albert, Ariel M Burns, Margaret Czesak, James C Overholser, George J Jurjus, Herbert Y Meltzer, Lisa C Konick, Lesa Dieter, Nicole Herbst, Warren May, Grazyna Rajkowska, Craig A Stockmeier, Mark C Austi. Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder. The international journal of neuropsychopharmacology. vol 12. issue 2. 2009-06-16. PMID:18561871. |
nudr immunoreactivity as measured by western blot was significantly decreased in the prefrontal cortex of female depressed subjects (42%, p=0.02) and unchanged in male depressed subjects relative to gender-matched control subjects. |
2009-06-16 |
2023-08-12 |
human |