| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Proshanta Roy, Ilenia Martinelli, Michele Moruzzi, Federica Maggi, Consuelo Amantini, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Francesco Amenta, Seyed Khosrow Tayebati, Daniele Tomasson. Ion channels alterations in the forebrain of high-fat diet fed rats. European journal of histochemistry : EJH. vol 65. issue s1. 2021-11-24. PMID:34814650. |
qrt-pcr, western blot, and immunochemistry analysis were performed in the frontal cortex (fc) and hippocampus (hip). |
2021-11-24 |
2023-08-13 |
rat |
| Samira Rostami, Abbas Haghparast, Rana Fayazmilan. The role of pre-pubertal training history on hippocampal neurotrophic factors and glucocorticoid receptor protein levels in adult male rats. Neuroscience letters. vol 752. 2021-11-22. PMID:33771578. |
western blot analysis revealed a significant increase in hippocampal bdnf and vegf protein levels in both ee and cet groups (p < 0.001), along with an increase in gr protein levels. |
2021-11-22 |
2023-08-13 |
rat |
| Alireza Moein Alsadat, Farnaz Nikbakht, Hadiseh Hossein Nia, Fereshteh Golab, Yasaman Khadem, Mahmoud Barati, Somayeh Vazifekha. GSK-3β as a target for apigenin-induced neuroprotection against Aβ 25-35 in a rat model of Alzheimer's disease. Neuropeptides. vol 90. 2021-11-22. PMID:34597878. |
immunohistochemistry and western blot analysis showed that apigenin significantly reduced the hyperphosphorylation of tau levels in the hippocampus. |
2021-11-22 |
2023-08-13 |
rat |
| Ilektra Anagnostou, Daniel Muñoz-Mayorga, Teresa Morale. Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice. Peptides. vol 135. 2021-11-19. PMID:33053420. |
neurodegeneration (fluoro-jade c), neuronal survival (neun) and astrogliosis (gfap) markers were identified with immunohistochemistry in the ca1, ca3 and ca4 areas of the dorsal hippocampus, as well as prl-related protein levels by western blot in the whole hippocampus 48 h after excitotoxicity. |
2021-11-19 |
2023-08-13 |
mouse |
| Hu Lv, Ying Li, Qian Cheng, Jiawei Chen, Wei Che. Neuroprotective Effects Against Cerebral Ischemic Injury Exerted by Dexmedetomidine via the HDAC5/NPAS4/MDM2/PSD-95 Axis. Molecular neurobiology. vol 58. issue 5. 2021-11-19. PMID:33411316. |
immunohistochemistry, western blot analysis, and rt-qpcr were used to examine expression of hdac5, npas4, mdm2, and psd-95 in hippocampus tissues of mcao mice and ogd-treated neurons. |
2021-11-19 |
2023-08-13 |
mouse |
| Yaru Xie, Kaining Zhi, Xianfang Men. Effects and Mechanisms of Synaptotagmin-7 in the Hippocampus on Cognitive Impairment in Aging Mice. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34403042. |
our results indicated that synaptotagmin-7 expression significantly decreased in the hippocampus of d-galactose-induced or naturally aging mice when compared with healthy controls, as detected by western blot and quantitative reverse transcriptase-polymerase chain reaction analysis. |
2021-11-18 |
2023-08-13 |
mouse |
| Yuxin He, Zhili Liu, Yinpei Huang, Bing L. Role of the p38MAPK signaling pathway in hippocampal neuron autophagy in rats with chronic intermittent hypoxia. Journal of neurophysiology. vol 126. issue 4. 2021-11-17. PMID:34469698. |
hippocampal microtubule-associated proteins were detected by western blot. |
2021-11-17 |
2023-08-13 |
rat |
| Ying Huang, Xiangping Liao, Huaiwei Wang, Jianghong Luo, Shanquan Zhong, Ziliang Zhang, Fang Zhang, Jianping Chen, Fuhua Xi. Effects of imperatorin on apoptosis and synaptic plasticity in vascular dementia rats. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:33883654. |
real-time pcr and western blot were used for detecting pro- and antiapoptotic biomarkers, and the hippocampus synaptic damage was examined by transmission electron microscope. |
2021-11-12 |
2023-08-13 |
rat |
| Raheleh Baradaran, Fatemeh Rahimi Anbarkeh, Amir Delavar, Elham Moghtadaei Khorasgani, Neda Rahimian, Yusef Abbasi, Najmeh Jaber. Hippocampal asymmetry and regional dispersal of nAChRs alpha4 and alpha7 subtypes in the adult rat. Journal of chemical neuroanatomy. vol 116. 2021-11-10. PMID:34052301. |
after removing the brains, immunohistochemistry, real-time pcr, and western blot methods were applied to distinguish the presence of the receptors in the hippocampus. |
2021-11-10 |
2023-08-13 |
rat |
| Haiyang Wang, Yumeng Feng, Jiaying Sun, Wang Zhang, Zhibin Han, Shengkun Yu, Yifei Gu, Xingbo Cheng, Zhiguo Lin, Meng N. Methyl-CpG-Binding Domain Protein 3 Promotes Seizures by Recruiting Methyltransferase DNMT1 to Enhance TREM2 Methylation. Neurochemical research. vol 46. issue 9. 2021-11-03. PMID:34173118. |
the expression of mbd3 was determined by western blot in a hippocampal neuronal culture (hnc) epileptic model established using the low mg |
2021-11-03 |
2023-08-13 |
mouse |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
the expression of hippocampal protein and mrna levels of targets related to synaptic plasticity and insulin pathway was assessed by western blot and real-time quantitative pcr. |
2021-11-02 |
2023-08-13 |
rat |
| Saltuk Bugra Baltaci, Omer Unal, Elif Gulbahce-Mutlu, Haluk Gumus, Suray Pehlivanoglu, Ahmet Yardimci, Rasim Mogulkoc, Abdulkerim Kasim Baltac. The Role of Zinc Status on Spatial Memory, Hippocampal Synaptic Plasticity, and Insulin Signaling in icv-STZ-Induced Sporadic Alzheimer's-Like Disease in Rats. Biological trace element research. 2021-11-02. PMID:34727320. |
western blot analysis revealed that icv-stz treatment significantly reduced hippocampal psd95 and p-gsk3β, and zinc supplementation restored the normal protein levels. |
2021-11-02 |
2023-08-13 |
rat |
| Hongyan Wang, Jun Lu, Wen-Cong Gao, Xin Ma, Na Li, Zhituan Ding, Chunmei Wu, Maoceng Zhu, Guanrong Qiao, Chuang Xiao, Changhong Zhang, Chen Chen, Zhiying Weng, Weimin Yang, Chang-Bo Zhen. Donepezil down-regulates propionylation, 2-hydroxyisobutyrylation, butyrylation, succinylation, and crotonylation in the brain of bilateral common carotid artery occlusion-induced vascular dementia rats. Clinical and experimental pharmacology & physiology. vol 47. issue 10. 2021-10-29. PMID:32424975. |
in this study, we used western blot analysis to identify several novel ptms in the hippocampus of bccao rats that were treated with or without donepezil. |
2021-10-29 |
2023-08-13 |
rat |
| Mary Jasmin Ang, Sohi Kang, Changjong Moo. Melatonin alters neuronal architecture and increases cysteine-rich protein 1 signaling in the male mouse hippocampus. Journal of neuroscience research. vol 98. issue 11. 2021-10-29. PMID:32754943. |
additionally, western blot and immunohistochemical analyses in both in vivo and in vitro systems revealed significant increases in the level of cysteine-rich protein 1 (crp-1) protein, which is known to be involved in dendritic branching in mouse hippocampal neurons after melatonin treatment. |
2021-10-29 |
2023-08-13 |
mouse |
| Zahra Fatahi, Arman Zeinaddini-Meymand, Saeideh Karimi-Haghighi, Amir Haghparast, Fariba Khodagholi, Abbas Haghparas. BDNF and p-GSK3β in the hippocampus mediate the impairment of delay-based decision making in morphine-dependent rats. Neuroreport. vol 31. issue 17. 2021-10-26. PMID:33075004. |
after behavioral tests, bdnf level, p-gsk3β/gsk3β ratio, and p-creb/creb ratio in the hippocampus measured by western blot analysis. |
2021-10-26 |
2023-08-13 |
rat |
| Dun Yuan, Jun Huang, Xianrui Yuan, Jie Zhao, Weixi Jian. Zinc finger protein 667 expression is upregulated by cerebral ischemic preconditioning and protects cells from oxidative stress. Biomedical reports. vol 1. issue 4. 2021-10-21. PMID:24648981. |
the northern blot results demonstrated that znf667 expression was increased in the hippocampus and cortex at 12 and 24 h after cerebral ischemic pretreatment. |
2021-10-21 |
2023-08-12 |
rat |
| Yong-Qing Guo, Li-Na Zheng, Jian-Feng Wei, Xiao-Lai Hou, Shu-Zhen Yu, Wei-Wei Zhang, Jian-Min Jin. Expression of CCL2 and CCR2 in the hippocampus and the interventional roles of propofol in rat cerebral ischemia/reperfusion. Experimental and therapeutic medicine. vol 8. issue 2. 2021-10-21. PMID:25009636. |
the mrna expression levels of ccl2 and ccr2 in the hippocampus were analyzed by quantitative polymerase chain reaction, while the protein expression levels of ccl2 and ccr2 were determined by western blot analysis. |
2021-10-21 |
2023-08-13 |
rat |
| Fan Zhao, Chenyiyu Zhang, Dong Xiao, Weihua Zhang, Liping Zhou, Simeng Gu, Rong Q. Radix Scutellariae Ameliorates Stress-Induced Depressive-Like Behaviors via Protecting Neurons through the TGF Neural plasticity. vol 2020. 2021-10-14. PMID:33273910. |
the neuroprotective effect of rs was evaluated with the expression of hippocampal neuron-related markers and apoptosis-associated proteins by nissl staining, immunohistochemistry, and western blot. |
2021-10-14 |
2023-08-13 |
mouse |
| Chang-Hong Liu, Bo-Lun Zhao, Wen-Tao Li, Xiao-Hua Zhou, Zhe Jin, Li-Bin A. Changes in depressive-like behaviors induced by spinal cord injury based on the hypothalamic-pituitary-adrenal axis and hippocampal neurogenesis. Journal of integrative neuroscience. vol 20. issue 3. 2021-10-14. PMID:34645096. |
serum corticosterone levels were examined by enzyme-linked immunosorbent assay and hippocampal glucocorticoid receptor levels were examined by western blot to evaluate the function of the hypothalamic-pituitary-adrenal axis. |
2021-10-14 |
2023-08-13 |
rat |
| Chang-Hong Liu, Bo-Lun Zhao, Wen-Tao Li, Xiao-Hua Zhou, Zhe Jin, Li-Bin A. Changes in depressive-like behaviors induced by spinal cord injury based on the hypothalamic-pituitary-adrenal axis and hippocampal neurogenesis. Journal of integrative neuroscience. vol 20. issue 3. 2021-10-14. PMID:34645096. |
adult hippocampal neurogenesis was assessed by testing hippocampal brain-derived neurotrophic factor and tropomyosin receptor kinase b levels by western blot and doublecortin levels by immunohistochemistry. |
2021-10-14 |
2023-08-13 |
rat |