| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sachio Matsushita, Mitsuru Kimura, Tomohiro Miyakawa, Aihide Yoshino, Masanobu Murayama, Toshihiro Masaki, Susumu Higuch. Association study of brain-derived neurotrophic factor gene polymorphism and alcoholism. Alcoholism, clinical and experimental research. vol 28. issue 11. 2005-03-01. PMID:15547445. |
brain-derived neurotrophic factor (bdnf) influences dopamine and serotonin neurotransmitters that are heavily linked to addiction. |
2005-03-01 |
2023-08-12 |
Not clear |
| Michael B Knable, Beata M Barci, Maree J Webster, James Meador-Woodruff, E Fuller Torre. Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. Molecular psychiatry. vol 9. issue 6. 2005-01-31. PMID:14708030. |
abnormal molecules included measures of synaptic density or neuronal plasticity (reelin, snap-25, bdnf, complexin i and ii), as well as parvalbumin, tyrosine receptor kinase a, glucocorticoid receptors, glutamate nr1 receptor subunits, serotonin 5ht2(a) and 5ht1(b) receptors, and dopamine d(5) receptors. |
2005-01-31 |
2023-08-12 |
Not clear |
| Jacob Pade Ramsøe Jacobsen, Arne Mør. The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. Brain research. vol 1024. issue 1-2. 2005-01-06. PMID:15451381. |
we also investigated if treatment-induced modulations of the tissue contents of 5-hydroxytryptamine (5-ht) and its metabolite, 5-hydroxy-indoleacetic acid (5-hiaa), were related to changes in bdnf mrna or protein expression. |
2005-01-06 |
2023-08-12 |
rat |
| Samina S Riaz, Spyridon Theofilopoulos, Eric Jauniaux, Gerald M Stern, Henry F Bradfor. The differentiation potential of human foetal neuronal progenitor cells in vitro. Brain research. Developmental brain research. vol 153. issue 1. 2004-12-21. PMID:15464216. |
it was found that, with the right cocktails of agents, serotonin (ser) (75 microm), acidic fibroblast growth factor (afgf) (10 ng/ml), bdnf (50 ng/ml) and forskolin (10 microm), these same cells could be directed down the serotonergic cell lineage pathway (as judged by the appearance of tryptophan hydroxylase (tph) positive immunoreactivity, and synthesis of 5-ht and its metabolites, secreted into the culture medium). |
2004-12-21 |
2023-08-12 |
human |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in neurosciences. vol 27. issue 10. 2004-11-30. PMID:15374669. |
bdnf and 5-ht: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. |
2004-11-30 |
2023-08-12 |
Not clear |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in neurosciences. vol 27. issue 10. 2004-11-30. PMID:15374669. |
brain-derived neurotrophic factor (bdnf) and serotonin (5-hydroxytryptamine, 5-ht) are known to regulate synaptic plasticity, neurogenesis and neuronal survival in the adult brain. |
2004-11-30 |
2023-08-12 |
Not clear |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in neurosciences. vol 27. issue 10. 2004-11-30. PMID:15374669. |
these two signals co-regulate one another such that 5-ht stimulates the expression of bdnf, and bdnf enhances the growth and survival of 5-ht neurons. |
2004-11-30 |
2023-08-12 |
Not clear |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in neurosciences. vol 27. issue 10. 2004-11-30. PMID:15374669. |
impaired 5-ht and bdnf signaling is central to depression and anxiety disorders, but could also play important roles in the pathogenesis of several age-related disorders, including insulin resistance syndrome, alzheimer's disease and huntington's disease. |
2004-11-30 |
2023-08-12 |
Not clear |
| Mark P Mattson, Stuart Maudsley, Bronwen Marti. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders. Trends in neurosciences. vol 27. issue 10. 2004-11-30. PMID:15374669. |
behavioral and pharmacological manipulations that enhance 5-ht and bdnf signaling could help promote healthy brain aging. |
2004-11-30 |
2023-08-12 |
Not clear |
| Y Liu, Y Ishida, K Shinoda, S Furukawa, S Nakamur. Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats. Brain research bulletin. vol 64. issue 1. 2004-10-15. PMID:15275959. |
in addition, the expression of brain-derived neurotrophic factor (bdnf) was increased in cortical regions where the 5-ht axon density was increased in response to stress. |
2004-10-15 |
2023-08-12 |
rat |
| Y Liu, Y Ishida, K Shinoda, S Furukawa, S Nakamur. Opposite morphological responses of partially denervated cortical serotonergic and noradrenergic axons to repeated stress in adult rats. Brain research bulletin. vol 64. issue 1. 2004-10-15. PMID:15275959. |
the stress-induced increase in bdnf expression may contribute to 5-ht axon sprouting following repeated stress. |
2004-10-15 |
2023-08-12 |
rat |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
late onset loss of hippocampal 5-ht and ne is accompanied by increases in bdnf protein expression in mice co-expressing mutant app and ps1. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
in addition, brain-derived neurotrophic factor (bdnf) protein levels were investigated since changes in bdnf are reported to occur in ad, and bdnf has been shown to have trophic effects on serotonin and norepinephrine neurons. |
2004-09-24 |
2023-08-12 |
mouse |
| Matthew E Szapacs, Adam L Numis, Anne M Andrew. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1. Neurobiology of disease. vol 16. issue 3. 2004-09-24. PMID:15262269. |
furthermore, in a different model of serotonergic and noradrenergic degeneration, bdnf protein levels were similarly increased in response to depletions in hippocampal serotonin and norepinephrine caused by the chemical neurotoxin 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-nh2-mptp). |
2004-09-24 |
2023-08-12 |
mouse |
| James B Koprich, Nicholas G Campbell, Jack W Lipto. Neonatal 3,4-methylenedioxymethamphetamine (ecstasy) alters dopamine and serotonin neurochemistry and increases brain-derived neurotrophic factor in the forebrain and brainstem of the rat. Brain research. Developmental brain research. vol 147. issue 1-2. 2004-05-03. PMID:14741762. |
in the current study, this model was employed to determine whether forebrain and brainstem dopamine (da) and 5-ht neurochemistry were altered 24 h after the last injection (p21), and whether brain-derived neurotrophic factor (bdnf) was upregulated in response to mdma exposure. |
2004-05-03 |
2023-08-12 |
rat |
| Prakasham Rumajogee, Daniel Vergé, Naïma Hanoun, Marie-Jeanne Brisorgueil, René Hen, Klaus-Peter Lesch, Michel Hamon, Marie-Christine Mique. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European journal of neuroscience. vol 19. issue 4. 2004-04-14. PMID:15009141. |
adaption of the serotoninergic neuronal phenotype in the absence of 5-ht autoreceptors or the 5-ht transporter: involvement of bdnf and camp. |
2004-04-14 |
2023-08-12 |
mouse |
| Prakasham Rumajogee, Daniel Vergé, Naïma Hanoun, Marie-Jeanne Brisorgueil, René Hen, Klaus-Peter Lesch, Michel Hamon, Marie-Christine Mique. Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. The European journal of neuroscience. vol 19. issue 4. 2004-04-14. PMID:15009141. |
these findings show that the up-regulatory mechanisms triggered by bdnf on serotoninergic neuronal number and neurite extension are different and that the latter are partially linked to 5-ht, probably through 5-ht1a autoreceptors. |
2004-04-14 |
2023-08-12 |
mouse |
| D L Murphy, G R Uhl, A Holmes, R Ren-Patterson, F S Hall, I Sora, S Detera-Wadleigh, K P Lesc. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes, brain, and behavior. vol 2. issue 6. 2004-01-15. PMID:14653307. |
this paper provides examples of experimentally-obtained interactions between quantitative variations in sert gene expression and variations in the expression of five other mouse genes: dat, net, maoa, 5-ht(1b) and bdnf. |
2004-01-15 |
2023-08-12 |
mouse |
| A S Ivy, F G Rodriguez, C Garcia, M J Chen, A A Russo-Neustad. Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759116. |
much evidence regarding the initial actions of antidepressant medications as well as exercise leads to the hypothesis that noradrenergic (ne) and/or serotonergic (5-ht) activation is a key element in the bdnf transcriptional elevation common to both interventions. |
2004-01-07 |
2023-08-12 |
Not clear |
| A S Ivy, F G Rodriguez, C Garcia, M J Chen, A A Russo-Neustad. Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759116. |
currently, we used short-term beta-adrenergic, 5-ht(1a), or 5-ht(2a/c) receptor blockade to characterize the influence of ne and 5-ht systems on bdnf transcription during physical exercise and antidepressant treatment. |
2004-01-07 |
2023-08-12 |
Not clear |