| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B A Luellen, L E Bianco, L M Schneider, A M Andrew. Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17156118. |
age-related loss of serotonin axons in the hippocampus was potentiated in bdnf(+/-) mice compared with wildtype mice at this late age, particularly in the ca1 subregion. |
2007-09-19 |
2023-08-12 |
mouse |
| B A Luellen, L E Bianco, L M Schneider, A M Andrew. Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17156118. |
by contrast, aging bdnf(+/-) mice showed increased serotonin innervation of the basomedial nucleus of the amygdala. |
2007-09-19 |
2023-08-12 |
mouse |
| B A Luellen, L E Bianco, L M Schneider, A M Andrew. Reduced brain-derived neurotrophic factor is associated with a loss of serotonergic innervation in the hippocampus of aging mice. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17156118. |
in vivo zero net flux microdialysis in awake mice showed a significant decrease in extracellular serotonin levels in the hippocampus in bdnf(+/-) mice at 20 months of age. |
2007-09-19 |
2023-08-12 |
mouse |
| Marek Lommatzsch, Anke Niewerth, Jens Klotz, Olaf Schulte-Herbrüggen, Christiana Zingler, Peter Schuff-Werner, J Christian Vircho. Platelet and plasma BDNF in lower respiratory tract infections of the adult. Respiratory medicine. vol 101. issue 7. 2007-09-11. PMID:17317133. |
analysis of the platelet marker serotonin (5-ht) suggested that the decrease of platelet bdnf is part of a non-specific release of platelet-derived mediators in this condition. |
2007-09-11 |
2023-08-12 |
Not clear |
| Z Rogóz, G Skuza, B Legutk. Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 2. 2007-07-26. PMID:17622693. |
the obtained results suggest that the enhancement of bdnf gene expression may be essential for the therapeutic effect of co-administration of imi and ama to drug-resistant depressed patients, and that among other mechanisms, 5-ht(2a) receptors possibly play some role in this effect. |
2007-07-26 |
2023-08-12 |
rat |
| Chi-Un Pae, Chul Lee, In-Ho Pai. Therapeutic implication of cocaine- and amphetamine-regulated transcript (CART) in the treatment of depression. Medical hypotheses. vol 69. issue 1. 2007-07-18. PMID:17196760. |
the regulation of the signal transduction pathways by cart by modulating neurotrophic factors, such as brain-derived neurotrophic factor (bdnf), kinases (trkb), and neurotransmitters (5-ht), can also contribute to the treatment of depression. |
2007-07-18 |
2023-08-12 |
Not clear |
| L C Daws, J L Munn, M F Valdez, T Frosto-Burke, J G Hensle. Serotonin transporter function, but not expression, is dependent on brain-derived neurotrophic factor (BDNF): in vivo studies in BDNF-deficient mice. Journal of neurochemistry. vol 101. issue 3. 2007-07-18. PMID:17254018. |
serotonin transporter function, but not expression, is dependent on brain-derived neurotrophic factor (bdnf): in vivo studies in bdnf-deficient mice. |
2007-07-18 |
2023-08-12 |
mouse |
| L C Daws, J L Munn, M F Valdez, T Frosto-Burke, J G Hensle. Serotonin transporter function, but not expression, is dependent on brain-derived neurotrophic factor (BDNF): in vivo studies in BDNF-deficient mice. Journal of neurochemistry. vol 101. issue 3. 2007-07-18. PMID:17254018. |
in the present study, we used high-speed chronoamperometry to examine serotonin (5-ht) transporter (5-htt) function in vivo in 2-, 5-, and 10-month-old brain-derived neurotrophic factor (bdnf)+/- mice. |
2007-07-18 |
2023-08-12 |
mouse |
| V E Golimbet, L I Abramova, V G Kaleda, M V Alfimova, G I Korovaĭtseva, O M Lavrushina, A N Barkhatov. [The molecular-genetic aspects of differentiation of schizoaffective psychosis and attack-like progressive schizophrenia]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 3. 2007-07-09. PMID:17500207. |
to clarify nosologic differences between schizoaffective psychosis (sap) and attack-like progressive schizophrenia at molecular-genetic level, the genetic polymorphism of serotonin receptor type 2a (5htr2a), serotonin transporter (5-httlrp), and brain-derived neurotrophic factor (bdnf) was studied in 563 patients with schizophrenia (mean age 37.7+/-14.4 years, age at disease onset 26.7+/-11.4 years), and 171 patients with sap (mean age 30.7+/-11.6 years, age at disease onset 24.9+/-8.5 years). |
2007-07-09 |
2023-08-12 |
human |
| B F P Broekman, M Olff, F Boe. The genetic background to PTSD. Neuroscience and biobehavioral reviews. vol 31. issue 3. 2007-06-28. PMID:17126903. |
they have tested hypotheses involving key candidate genes in the serotonin (5-htt), dopamine (drd2, dat), glucocorticoid (gr), gaba (gabrb), apolipoprotein systems (apoe2), brain-derived neurotrophic factor (bdnf) and neuropeptide y (npy). |
2007-06-28 |
2023-08-12 |
Not clear |
| B N Greenwood, P V Strong, T E Foley, R S Thompson, M Fleshne. Learned helplessness is independent of levels of brain-derived neurotrophic factor in the hippocampus. Neuroscience. vol 144. issue 4. 2007-05-21. PMID:17161541. |
bdnf suppression in physically active rats was produced by administering a single injection of the selective serotonin reuptake inhibitor fluoxetine (10 mg/kg) just prior to stress. |
2007-05-21 |
2023-08-12 |
human |
| Olaf Schulte-Herbrüggen, Rainer Hellweg, Sabine Chourbaji, Stephanie Ridder, Christiane Brandwein, Peter Gass, Heide Hörtnag. Differential regulation of neurotrophins and serotonergic function in mice with genetically reduced glucocorticoid receptor expression. Experimental neurology. vol 204. issue 1. 2007-05-10. PMID:17208231. |
morning and evening levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), 5-ht and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) were analyzed in representative brain regions of gr(+/-) and wildtype mice. |
2007-05-10 |
2023-08-12 |
mouse |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:17029036. |
gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and bdnf deficiencies. |
2007-04-24 |
2023-08-12 |
mouse |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:17029036. |
brain-derived neurotrophic factor (bdnf) supports serotonergic neuronal development and our recent study found that heterozygous mice lacking one bdnf gene allele interbred with male serotonin transporter (sert) knockout mice had greater reductions in brain tissue serotonin concentrations, greater increases in anxiety-like behaviors and greater acth responses to stress than found in the sert knockout mice alone. |
2007-04-24 |
2023-08-12 |
mouse |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:17029036. |
these findings support the hypothesis that estrogen may enhance bdnf function via its trkb receptor, leading to alterations in the serotonin circuits, which modulate anxiety-like behaviors. |
2007-04-24 |
2023-08-12 |
mouse |
| J R Grider, B E Pilan. The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 1. 2007-03-22. PMID:16973914. |
the peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-ht and neuronal cgrp but not bdnf. |
2007-03-22 |
2023-08-12 |
rat |
| J R Grider, B E Pilan. The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 1. 2007-03-22. PMID:16973914. |
the release of serotonin (5-ht), brain-derived neurotrophic factor (bdnf), and cgrp was measured in all three compartments. |
2007-03-22 |
2023-08-12 |
rat |
| Olaf Schulte-Herbrüggen, Sabine Chourbaji, Stephanie Ridder, Christiane Brandwein, Peter Gass, Heide Hörtnagl, Rainer Hellwe. Stress-resistant mice overexpressing glucocorticoid receptors display enhanced BDNF in the amygdala and hippocampus with unchanged NGF and serotonergic function. Psychoneuroendocrinology. vol 31. issue 10. 2007-03-19. PMID:17098367. |
here, we analyzed gr overexpressing mice for morning and evening content of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and the tissue levels of serotonin and its metabolite 5-hydroxyindoleacetic acid) in brain areas suspected to be involved in stress adaptation. |
2007-03-19 |
2023-08-12 |
mouse |
| Shih-Jen Tsa. The P11, tPA/plasminogen system and brain-derived neurotrophic factor: Implications for the pathogenesis of major depression and the therapeutic mechanism of antidepressants. Medical hypotheses. vol 68. issue 1. 2007-01-30. PMID:16890384. |
evidence from animal and human studies suggests that a disturbance in serotonergic (5-ht) activity and/or brain-derived neurotrophic factor (bdnf) signaling may be implicated in the pathogenesis of mdd. |
2007-01-30 |
2023-08-12 |
mouse |
| Rainer Hellweg, Maha Zueger, Katharina Fink, Heide Hörtnagl, Peter Gas. Olfactory bulbectomy in mice leads to increased BDNF levels and decreased serotonin turnover in depression-related brain areas. Neurobiology of disease. vol 25. issue 1. 2007-01-23. PMID:16990008. |
olfactory bulbectomy in mice leads to increased bdnf levels and decreased serotonin turnover in depression-related brain areas. |
2007-01-23 |
2023-08-12 |
mouse |