Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Susanne H M Gruber, Stefan Bren\\xc3\\xa. Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats. Hippocampus. vol 17. issue 12. 2008-02-29. PMID:17879375.' |
group housed sprague dawley rats had a higher expression of bdnf, npy, and the serotonin 5ht2a receptor mrna than "depressed" flinders sensitive line. |
2008-02-29 |
2023-08-12 |
rat |
Nicolas P Lapointe, Roth-Visal Ung, Pierre A Guerti. Plasticity in sublesionally located neurons following spinal cord injury. Journal of neurophysiology. vol 98. issue 5. 2008-02-25. PMID:17881483. |
some of these modifications include changes in the expression of immediate early genes (e.g., c-fos and nor-1), tnf-alpha, preprodynorphin, neurotrophic factors (e.g., bdnf and nt-3), and several subtypes of transmembranal receptors (e.g., 5-ht(1a) and 5-ht(2a)). |
2008-02-25 |
2023-08-12 |
Not clear |
Jens R Wendland, Matthew R Kruse, Kiara R Cromer, Kiara C Cromer, Dennis L Murph. A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17375136. |
both serotonin transporter (slc6a4) and brain-derived neurotrophic factor (bdnf) genes have shown positive associations with obsessive-compulsive disorder (ocd) and some other psychiatric disorders, but these results have not been consistently replicated. |
2008-02-14 |
2023-08-12 |
Not clear |
Regina Hünnerkopf, Alexander Strobel, Lise Gutknecht, Burkhard Brocke, Klaus Peter Lesc. Interaction between BDNF Val66Met and dopamine transporter gene variation influences anxiety-related traits. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 12. 2008-02-14. PMID:17392738. |
in the present study, we evaluated the impact of the bdnf val66met polymorphism on individual differences in personality traits in a sample of healthy volunteers in relation to other common gene variants thought to be involved in the pathophysiology of affective disorders, such as the serotonin transporter promoter polymorphism (5-httlpr) and a variable number of tandem repeat polymorphism of the dopamine transporter gene (dat vntr). |
2008-02-14 |
2023-08-12 |
human |
Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
interaction between bdnf and serotonin: role in mood disorders. |
2008-02-14 |
2023-08-12 |
Not clear |
Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
brain-derived neurotrophic factor (bdnf) and serotonin (5-hydroxytryptamine, 5-ht) are two seemingly distinct signaling systems that play regulatory roles in many neuronal functions including survival, neurogenesis, and synaptic plasticity. |
2008-02-14 |
2023-08-12 |
Not clear |
Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
bdnf promotes the survival and differentiation of 5-ht neurons. |
2008-02-14 |
2023-08-12 |
Not clear |
Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
conversely, administration of antidepressant selective serotonin reuptake inhibitors (ssris) enhances bdnf gene expression. |
2008-02-14 |
2023-08-12 |
Not clear |
Keri Martinowich, Bai L. Interaction between BDNF and serotonin: role in mood disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 1. 2008-02-14. PMID:17882234. |
there is also evidence for synergism between the two systems in affective behaviors and genetic epitasis between bdnf and the serotonin transporter genes. |
2008-02-14 |
2023-08-12 |
Not clear |
Smita Thakker-Varia, Jennifer Jernstedt Krol, Jacob Nettleton, Parizad M Bilimoria, Debra A Bangasser, Tracey J Shors, Ira B Black, Janet Alde. The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 45. 2007-12-06. PMID:17989282. |
to identify genes downstream of bdnf that may play roles in psychiatric disorders, we examined a subset of bdnf-induced genes also regulated by 5-ht (serotonin), which includes the neuropeptide vgf (nonacronymic). |
2007-12-06 |
2023-08-12 |
mouse |
Janusz K Rybakowski, Aleksandra Suwalska, Maria Skibinska, Monika Dmitrzak-Weglarz, Anna Leszczynska-Rodziewicz, Joanna Hause. Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 6. 2007-11-07. PMID:17373693. |
response to lithium prophylaxis: interaction between serotonin transporter and bdnf genes. |
2007-11-07 |
2023-08-12 |
Not clear |
Janusz K Rybakowski, Aleksandra Suwalska, Maria Skibinska, Monika Dmitrzak-Weglarz, Anna Leszczynska-Rodziewicz, Joanna Hause. Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 6. 2007-11-07. PMID:17373693. |
both serotonin transporter and brain-derived neurotrophic factor (bdnf) genes have been previously implicated in the efficacy of lithium prophylaxis. |
2007-11-07 |
2023-08-12 |
Not clear |
Janusz K Rybakowski, Aleksandra Suwalska, Maria Skibinska, Monika Dmitrzak-Weglarz, Anna Leszczynska-Rodziewicz, Joanna Hause. Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 6. 2007-11-07. PMID:17373693. |
the aim of the present study was to assess a possible interaction between serotonin transporter genotype (5httlpr) and bdnf val66met polymorphism, and the prophylactic response to lithium. |
2007-11-07 |
2023-08-12 |
Not clear |
Manabu Amano, Katsuya Suemaru, Ranji Cui, Yuichi Umeda, Bingjin Li, Yutaka Gomita, Hiromu Kawasaki, Hiroaki Arak. Effects of physical and psychological stress on 5-HT2A receptor-mediated wet-dog shake responses in streptozotocin-induced diabetic rats. Acta medica Okayama. vol 61. issue 4. 2007-10-23. PMID:17726509. |
in the present studies, we examined the behavioral changes in streptozotocin-induced diabetic rats, and investigated the effects of physical and psychological stress on the hippocampal bdnf levels and on the serotonin 2a (5-ht(2a)) receptor-mediated wet-dog shake responses. |
2007-10-23 |
2023-08-12 |
rat |
G de Foubert, M J O'Neill, T S C Zetterströ. Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. Neuroscience. vol 147. issue 3. 2007-10-19. PMID:17560041. |
the present study investigated the effects of 5-ht(6)-receptor activation on hippocampal and cortical levels of mrna expression of bdnf and arc in the rat. |
2007-10-19 |
2023-08-12 |
rat |
G de Foubert, M J O'Neill, T S C Zetterströ. Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. Neuroscience. vol 147. issue 3. 2007-10-19. PMID:17560041. |
the selective 5-ht(6)-receptor agonist ly-586713 was administered acutely (0.1-10 mg/kg, s.c.) and mrna levels of bdnf and arc were measured 18 h later. |
2007-10-19 |
2023-08-12 |
rat |
G de Foubert, M J O'Neill, T S C Zetterströ. Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. Neuroscience. vol 147. issue 3. 2007-10-19. PMID:17560041. |
the up-regulation in bdnf expression observed at 1 mg/kg was completely blocked by pre-treatment with the selective 5-ht(6)-receptor antagonist sb-271046 (10 mg/kg, s.c.). |
2007-10-19 |
2023-08-12 |
rat |
G de Foubert, M J O'Neill, T S C Zetterströ. Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. Neuroscience. vol 147. issue 3. 2007-10-19. PMID:17560041. |
the results presented here provide the first evidence for the involvement of the 5-ht(6) receptor in regulating bdnf and arc mrna expression, suggesting that ly-586713 has potential effects on neuronal plasticity. |
2007-10-19 |
2023-08-12 |
rat |
G de Foubert, M J O'Neill, T S C Zetterströ. Acute onset by 5-HT(6)-receptor activation on rat brain brain-derived neurotrophic factor and activity-regulated cytoskeletal-associated protein mRNA expression. Neuroscience. vol 147. issue 3. 2007-10-19. PMID:17560041. |
overall, these findings suggest that, as opposed to more general 5-ht receptor activation by, for example, antidepressants, direct 5-ht(6)-receptor activation results in a more rapid rise in bdnf and arc mrna expression which does not require repeated administration. |
2007-10-19 |
2023-08-12 |
rat |
Ying Xu, Baoshan Ku, Li Cui, Xuejun Li, Philip A Barish, Thomas C Foster, William O Ogl. Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats. Brain research. vol 1162. 2007-10-19. PMID:17617388. |
in addition, curcumin significantly prevented the stress-induced decrease in 5-ht(1a) mrna and bdnf protein levels in the hippocampal subfields, two molecules involved in hippocampal neurogenesis. |
2007-10-19 |
2023-08-12 |
rat |