| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francisco J Flores-Ramirez, Anapaula Themann, Jorge A Sierra-Fonseca, Israel Garcia-Carachure, Samuel A Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L Warren, Alfred J Robison, Sergio D Iñigue. Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33833356. |
an additional goal was to assess the impact of adolescent flx pretreatment, and its re-exposure in adulthood, on serotonin transporters (5-htt) and brain-derived-neurotrophic-factor (bdnf)-related signaling markers (trkb-erk1/2-creb-probdnf-mbdnf) within the hippocampus and prefrontal cortex. |
2021-11-08 |
2023-08-13 |
mouse |
| Jeremy S Lum, Katrina M Bird, Jennifer Wilkie, Samuel J Millard, Sachie Pallimulla, Kelly A Newell, Ian M Wrigh. Prenatal methadone exposure impairs adolescent cognition and GABAergic neurodevelopment in a novel rat model of maternal methadone treatment. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33571606. |
immunoblots of the adolescent prefrontal cortex and hippocampus showed methadone-exposed offspring displayed reduced levels of mature bdnf, in addition to the gabaergic proteins, gad67 and parvalbumin, in a sex- and brain region-specific fashion. |
2021-11-01 |
2023-08-13 |
rat |
| Janine Karina Hideko Alfenas Horita, Maria Carolina Machado da Silva, Carolina Zaniboni Ferrari, Erica Leandro Marciano Vieira, Fabricio A Moreira, Antônio Carlos Pinheiro de Oliveira, Helton José Rei. Evaluation of Brain Cytokines and the Level of Brain-Derived Neurotrophic Factor in an Inflammatory Model of Depression. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33176302. |
inflammatory processes are likely involved in its pathophysiology, but the underlying mechanisms have remained uncertain.here, we used the model of systemic lipopolysaccharide (lps) injection to test the hypothesis that depressive-like behaviors occur along with changes in the levels of cytokines and brain-derived neurotrophic factor (bdnf) in the hippocampus (hc), prefrontal cortex (pfc), and hypothalamus (ht), and can be prevented by dexamethasone administration. |
2021-10-28 |
2023-08-13 |
Not clear |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and bdnf in the hippocampus and prefrontal cortex of rats with sporadic alzheimer-like disease. |
2021-10-27 |
2023-08-13 |
rat |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
we measured brain-derived-neurotrophic factor (bdnf), tumour-necrosis factor (tnf)-α, and interleukin (il)-10 levels in the hippocampus and prefrontal cortex of animals. |
2021-10-27 |
2023-08-13 |
rat |
| Saeed Naghibi, Mohammad Shariatzadeh Joneydi, Ali Barzegari, Azam Davoodabadi, Amirhossein Ebrahimi, Elham Eghdami, Narges Fahimpour, Mahmood Ghorbani, Ehsan Mohammadikia, Mozhgan Rostami, Ali-Akbar Salar. Treadmill exercise sex-dependently alters susceptibility to depression-like behaviour, cytokines and BDNF in the hippocampus and prefrontal cortex of rats with sporadic Alzheimer-like disease. Physiology & behavior. vol 241. 2021-10-27. PMID:34536437. |
we also found that treadmill exercise decreased depression-related behaviours and tnf-α in the hippocampus and prefrontal cortex, and increased il-10 in the prefrontal cortex and bdnf in the hippocampus of female ald-induced rats. |
2021-10-27 |
2023-08-13 |
rat |
| Philip W Gol. The PPARg System in Major Depression: Pathophysiologic and Therapeutic Implications. International journal of molecular sciences. vol 22. issue 17. 2021-10-20. PMID:34502154. |
brain-derived neurotrophic factor (bdnf) is markedly depleted in these areas, and is thought to contribute to the neurodegeneration of the subgenual prefrontal cortex and the hippocampus. |
2021-10-20 |
2023-08-13 |
Not clear |
| Hattaya Benya-Aphikul, Varisa Pongrakhananon, Paninee Chetprayoon, Thongchai Sooksawate, Ratchanee Rodsir. Neuronal growth and synaptogenesis are inhibited by prenatal methamphetamine exposure leading to memory impairment in adolescent and adult mice. Toxicology letters. vol 351. 2021-10-08. PMID:34461196. |
bdnf expression was enhanced in the prefrontal cortex and striatum of ma-exposed pnd14 mice. |
2021-10-08 |
2023-08-13 |
mouse |
| Parviz Naderipoor, Mohammad Amani, Ali Abedi, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Alterations in the behavior, cognitive function, and BDNF level in adult male rats following neonatal blockade of GABA-A receptors. Brain research bulletin. vol 169. 2021-10-07. PMID:33440220. |
therefore, we examined the effects of neonatal blockade of gaba-a receptors by bicuculline on behavior, cognitive function, and hippocampal and prefrontal cortex (pfc) brain-derived neurotrophic factors level (bdnf) in adulthood. |
2021-10-07 |
2023-08-13 |
rat |
| Parviz Naderipoor, Mohammad Amani, Ali Abedi, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Alterations in the behavior, cognitive function, and BDNF level in adult male rats following neonatal blockade of GABA-A receptors. Brain research bulletin. vol 169. 2021-10-07. PMID:33440220. |
after the ending of the behavioral tests, the rats were sacrificed under deep anesthesia and the hippocampi and prefrontal cortex (pfc) of the brain were removed for assessing the bdnf mrna expression. |
2021-10-07 |
2023-08-13 |
rat |
| Parviz Naderipoor, Mohammad Amani, Ali Abedi, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Alterations in the behavior, cognitive function, and BDNF level in adult male rats following neonatal blockade of GABA-A receptors. Brain research bulletin. vol 169. 2021-10-07. PMID:33440220. |
meanwhile, this drug at a low dose impaired this type of memory and increased pfc bdnf level. |
2021-10-07 |
2023-08-13 |
rat |
| Siobhan Robinson, Allison S Mogul, Elisa M Taylor-Yeremeeva, Amber Khan, Anthony D Tirabassi, Hoau-Yan Wan. Stress Diminishes BDNF-stimulated TrkB Signaling, TrkB-NMDA Receptor Linkage and Neuronal Activity in the Rat Brain. Neuroscience. vol 473. 2021-10-01. PMID:34298123. |
(2) after stress, bdnf stimulation enhanced trkb-nmdar linkage in pfc, suggestive of compensatory mechanisms in this region. |
2021-10-01 |
2023-08-13 |
rat |
| Hajime Miyanishi, Atsumi Nitt. A Role of BDNF in the Depression Pathogenesis and a Potential Target as Antidepressant: The Modulator of Stress Sensitivity "Shati/Nat8l-BDNF System" in the Dorsal Striatum. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577589. |
we reviewed a novel finding of bdnf function in the dorsal striatum, which induces vulnerability to social stress, in addition to recent research progress regarding the brain regional functions of bdnf, including the prefrontal cortex, hippocampus, and nucleus accumbens. |
2021-10-01 |
2023-08-13 |
Not clear |
| Nona Sakhaie, Farshid Sadegzadeh, Raziyeh Dehghany, Omid Adak, Saadati Hakime. Sex-dependent effects of chronic fluoxetine exposure during adolescence on passive avoidance memory, nociception, and prefrontal brain-derived neurotrophic factor mRNA expression. Brain research bulletin. vol 162. 2021-09-29. PMID:32585291. |
therefore, in the present experimental study, we examined the effects of chronic fluoxetine exposure (5 mg/kg/day, gavage) throughout adolescence (postnatal day 21-60) on passive avoidance learning and memory, pain sensitivity, and brain-derived neurotrophic factor (bdnf) level in the prefrontal cortex of young adult male and female rats. |
2021-09-29 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Raziyeh Dehghany, Omid Adak, Saadati Hakime. Sex-dependent effects of chronic fluoxetine exposure during adolescence on passive avoidance memory, nociception, and prefrontal brain-derived neurotrophic factor mRNA expression. Brain research bulletin. vol 162. 2021-09-29. PMID:32585291. |
the mrna expression of bdnf in the prefrontal cortex significantly increased in fluoxetine- exposed female rats. |
2021-09-29 |
2023-08-13 |
rat |
| Priscila B Rosa, Luis E B Bettio, Vivian B Neis, Morgana Moretti, Fernanda N Kaufmann, Mauren K Tavares, Isabel Werle, Yasmim Dalsenter, Nicolle Platt, Axel F Rosado, Daiane B Fraga, Isabella A Heinrich, Andiara E Freitas, Rodrigo B Leal, Ana Lúcia S Rodrigue. Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling. Purinergic signalling. vol 17. issue 2. 2021-09-28. PMID:33712981. |
in the prefrontal cortex, bdnf level was increased only 1 h after guanosine treatment. |
2021-09-28 |
2023-08-13 |
mouse |
| Jana Osacka, Romana Koprdova, Andrej Tillinger, Zdenko Pirnik, Alexander Kis. Haloperidol and aripiprazole impact on the BDNF and glucocorticoid receptor levels in the rat hippocampus and prefrontal cortex: effect of the chronic mild stress. Endocrine regulations. vol 55. issue 3. 2021-09-15. PMID:34523299. |
haloperidol and aripiprazole impact on the bdnf and glucocorticoid receptor levels in the rat hippocampus and prefrontal cortex: effect of the chronic mild stress. |
2021-09-15 |
2023-08-13 |
rat |
| Helene A Fachim, Fabiana Corsi-Zuelli, Camila M Loureiro, Sri-Arun Iamjan, Rosana Shuhama, Samia Joca, Paulo Rossi Menezes, Adrian Heald, Paulo Louzada-Junior, Caroline F Dalton, Cristina Marta Del-Ben, Gavin P Reynold. Early-life stress effects on BDNF DNA methylation in first-episode psychosis and in rats reared in isolation. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:33259836. |
dna was extracted from human blood and rat brain (prefrontal cortex and hippocampus), bisulphite-converted and the methylation of equivalent sequences within bdnf exon iv determined by pyrosequencing. |
2021-09-02 |
2023-08-13 |
human |
| Kevin J Zhang, Rajan A Ramdev, Nicholas J Tuta, Mark D Spritze. Dose-dependent effects of testosterone on spatial learning strategies and brain-derived neurotrophic factor in male rats. Psychoneuroendocrinology. vol 121. 2021-08-24. PMID:32892065. |
furthermore, we quantified concentrations of brain-derived neurotrophic factor (pro-, mature-, and total bdnf) in the prefrontal cortex, hippocampus, and striatum. |
2021-08-24 |
2023-08-13 |
rat |
| Yunxia Niu, Tao Wang, Shan Liang, Wei Li, Xu Hu, Xiaoli Wu, Feng Ji. Sex-dependent aberrant PFC development in the adolescent offspring rats exposed to variable prenatal stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 80. issue 6. 2021-08-12. PMID:32358823. |
the study tested the concentration of brain-derived neurotrophic factor (bdnf), cluster of differentiation 68 (cd68), synaptotagmin-1(syt-1), 5-hydroxytryptamine (5-ht), dopamine (da), glucocorticoid receptors (grs) and oestrogen receptors (ers) in the pfc (prefrontal cortex). |
2021-08-12 |
2023-08-13 |
rat |