| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Remy Verhaeghe, Vance Gao, Sara Morley-Fletcher, Hammou Bouwalerh, Gilles Van Camp, Francesca Cisani, Ferdinando Nicoletti, Stefania Maccar. Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats. GeroScience. 2021-05-15. PMID:33983623. |
in contrast, in female aged rats, prs enhanced the expression of mrs and brain-derived neurotrophic factor (bdnf) in the ventral hippocampus and the expression of glial fibrillary acidic protein (gfap) and bdnf in the prefrontal cortex. |
2021-05-15 |
2023-08-13 |
rat |
| Xi-Xi Li, Yun Yu, Xiu-Yuan Lang, Cheng-Yong Jiang, Rongfeng Lan, Xiao-Yan Qi. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside Restores BDNF-TrkB and FGF2-Akt Signaling Axis to Attenuate Stress-induced Depression. Neuroscience. vol 430. 2021-05-14. PMID:32007553. |
crs produced downregulation of antioxidants, the decline of brain-derived neurotrophic factor (bdnf), fibroblast growth factor 2 (fgf2) and associated signaling regulators in the hippocampus and prefrontal cortex, corresponding to the behavioral inability and anhedonia. |
2021-05-14 |
2023-08-13 |
mouse |
| Kelsey E Brass, Nathan Herndon, Sarah A Gardner, Jennifer L Grindstaff, Polly Campbel. Intergenerational effects of paternal predator cue exposure on behavior, stress reactivity, and neural gene expression. Hormones and behavior. vol 124. 2021-04-28. PMID:32534838. |
effects of paternal treatment on neural gene expression were limited to the prefrontal cortex, with increased mineralocorticoid receptor expression and a trend towards increased bdnf expression in offspring of tmt-exposed males. |
2021-04-28 |
2023-08-13 |
mouse |
| Marie Woelfer, Meng Li, Lejla Colic, Thomas Liebe, Xin Di, Bharat Biswal, James Murrough, Volkmar Lessmann, Tanja Brigadski, Martin Walte. Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 21. issue 9. 2021-04-27. PMID:31680600. |
ketamine-induced changes in plasma brain-derived neurotrophic factor (bdnf) levels are associated with the resting-state functional connectivity of the prefrontal cortex. |
2021-04-27 |
2023-08-13 |
Not clear |
| Marie Woelfer, Meng Li, Lejla Colic, Thomas Liebe, Xin Di, Bharat Biswal, James Murrough, Volkmar Lessmann, Tanja Brigadski, Martin Walte. Ketamine-induced changes in plasma brain-derived neurotrophic factor (BDNF) levels are associated with the resting-state functional connectivity of the prefrontal cortex. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 21. issue 9. 2021-04-27. PMID:31680600. |
ketamine, an n-methyl-d-aspartate receptor antagonist and putative antidepressant, may increase synaptic plasticity in prefrontal cortex through higher expression of bdnf. |
2021-04-27 |
2023-08-13 |
Not clear |
| Farshid Sadegzadeh, Nona Sakhaie, Khatereh Isazadehfar, Hakimeh Saadat. Effects of exposure to enriched environment during adolescence on passive avoidance memory, nociception, and prefrontal BDNF level in adult male and female rats. Neuroscience letters. vol 732. 2021-04-27. PMID:32522604. |
therefore, the present experiment was aimed to assess the effects of ee during adolescence on passive avoidance learning and memory, nociception, and prefrontal cortex (pfc) bdnf mrna levels in the adult male and female rats. |
2021-04-27 |
2023-08-13 |
rat |
| Farshid Sadegzadeh, Nona Sakhaie, Khatereh Isazadehfar, Hakimeh Saadat. Effects of exposure to enriched environment during adolescence on passive avoidance memory, nociception, and prefrontal BDNF level in adult male and female rats. Neuroscience letters. vol 732. 2021-04-27. PMID:32522604. |
findings of our study also showed an increased bdnf level in the pfc of female animals. |
2021-04-27 |
2023-08-13 |
rat |
| Farshid Sadegzadeh, Nona Sakhaie, Khatereh Isazadehfar, Hakimeh Saadat. Effects of exposure to enriched environment during adolescence on passive avoidance memory, nociception, and prefrontal BDNF level in adult male and female rats. Neuroscience letters. vol 732. 2021-04-27. PMID:32522604. |
as a result, sex differences can affect the expression of bdnf mrna in the pfc. |
2021-04-27 |
2023-08-13 |
rat |
| Farshid Sadegzadeh, Nona Sakhaie, Khatereh Isazadehfar, Hakimeh Saadat. Effects of exposure to enriched environment during adolescence on passive avoidance memory, nociception, and prefrontal BDNF level in adult male and female rats. Neuroscience letters. vol 732. 2021-04-27. PMID:32522604. |
further research concerning the precise mechanisms underlying sex hormone-dependent production of bdnf in pfc is critical. |
2021-04-27 |
2023-08-13 |
rat |
| Adriano José Maia Chaves Filho, Natássia Lopes Cunha, Alana Gomes de Souza, Michele Verde-Ramo Soares, Paloma Marinho Jucá, Tatiana de Queiroz, João Victor Souza Oliveira, Samira S Valvassori, Tatiana Barichello, Joao Quevedo, David de Lucena, Danielle S Maced. The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by D-amphetamine and augments lithium effects in mice: Relevance for bipolar disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 99. 2021-03-31. PMID:31954756. |
li + lira240 augmented li antioxidant effects and greatly reversed amph-induced bdnf changes in pfc and hippocampus. |
2021-03-31 |
2023-08-13 |
mouse |
| Tin-Tin Win-Shwe, Chaw Kyi-Tha-Thu, Yuji Fujitani, Shinji Tsukahara, Seishiro Hiran. Perinatal Exposure to Diesel Exhaust-Origin Secondary Organic Aerosol Induces Autism-Like Behavior in Rats. International journal of molecular sciences. vol 22. issue 2. 2021-03-30. PMID:33430368. |
serotonin receptor (5-ht(5b)) and brain-derived neurotrophic factor (bdnf) mrnas were downregulated whereas interleukin 1 β (il-β) and heme oxygenase 1 (ho-1) mrnas were upregulated in the prefrontal cortex of male and female rats exposed to de-soa. |
2021-03-30 |
2023-08-13 |
rat |
| Alessandra Berry, Monica Mazzelli, Chiara Musillo, Marco Andrea Riva, Annamaria Cattaneo, Francesca Cirull. High-fat diet during adulthood interacts with prenatal stress, affecting both brain inflammatory and neuroendocrine markers in male rats. The European journal of neuroscience. 2021-03-26. PMID:33711185. |
changes in the expression levels of inflammatory (il-1β, tnf-α, il-6) and of stress response mediators (nr3c1, fkbp5) as well as of mood and metabolic regulators (bdnf, ghs-r) were investigated in the hippocampus, prefrontal cortex and hypothalamus, brain regions involved in the pathogenesis of depression and prone to inflammation in response to stress. |
2021-03-26 |
2023-08-13 |
rat |
| Yann Ehinger, Khanhky Phamluong, David Darevesky, Melanie Welman, Jeffrey J Moffat, Samuel A Sakhai, Ellanor L Whiteley, Anthony L Berger, Sophie Laguesse, Mehdi Farokhnia, Lorenzo Leggio, Marie Lordkipanidzé, Dorit Ro. Differential correlation of serum BDNF and microRNA content in rats with rapid or late onset of heavy alcohol use. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32135570. |
heavy alcohol use reduces the levels of the brain-derived neurotrophic factor (bdnf) in the prefrontal cortex of rodents through the upregulation of micrornas (mirs) targeting bdnf mrna. |
2021-03-25 |
2023-08-13 |
rat |
| Lei Tong, Ming-Da Li, Peng-Yin Nie, Yao Chen, Yu-Lu Chen, Li-Li J. miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF. Neurobiology of stress. vol 14. 2021-03-16. PMID:33718536. |
mir-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in pfc, and upregulates the expression of mecp2 and bdnf. |
2021-03-16 |
2023-08-13 |
rat |
| Lei Tong, Ming-Da Li, Peng-Yin Nie, Yao Chen, Yu-Lu Chen, Li-Li J. miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF. Neurobiology of stress. vol 14. 2021-03-16. PMID:33718536. |
the level of mir-132 in the prefrontal cortex (pfc) was increased and intraventricular injection of anti-mir-132 could significantly improve the anxiety-like behavior of rats exposed to sps through mecp2 and the subsequent upregulation of bdnf levels. |
2021-03-16 |
2023-08-13 |
rat |
| Lei Tong, Ming-Da Li, Peng-Yin Nie, Yao Chen, Yu-Lu Chen, Li-Li J. miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF. Neurobiology of stress. vol 14. 2021-03-16. PMID:33718536. |
then tropomyosin-related kinase b (trkb) and downstream signals, including map kinase erk1/2 and phosphoinositol 3-kinase (pi3k)/akt pathways, were activated by bdnf upregulation, and might participate in regulating dendritic complexity and the expression of postsynaptic density-95 (psd95) and synapsin i in the pfc of sps rats. |
2021-03-16 |
2023-08-13 |
rat |
| Paola Brivio, Giulia Sbrini, Giulia Corsini, Maria Serena Paladini, Giorgio Racagni, Raffaella Molteni, Francesca Calabres. Chronic Restraint Stress Inhibits the Response to a Second Hit in Adult Male Rats: A Role for BDNF Signaling. International journal of molecular sciences. vol 21. issue 17. 2021-02-23. PMID:32872446. |
hence, we investigated the long-lasting effects of chronic restraint stress (crs) and its influence on the modifications induced by the exposure to a second hit on brain-derived neurotrophic factor (bdnf) signaling in the prefrontal cortex (pfc). |
2021-02-23 |
2023-08-13 |
rat |
| Dean-Chuan Wang, Hwai-Ting Lin, Yi-Ju Lee, Hsien-Fu Yu, Sin-Ru Wu, Muhammad Usama Qama. Recovery of BDNF and CB1R in the Prefrontal Cortex Underlying Improvement of Working Memory in Prenatal DEHP-Exposed Male Rats after Aerobic Exercise. International journal of molecular sciences. vol 21. issue 11. 2021-02-16. PMID:32485872. |
recovery of bdnf and cb1r in the prefrontal cortex underlying improvement of working memory in prenatal dehp-exposed male rats after aerobic exercise. |
2021-02-16 |
2023-08-13 |
rat |
| Dean-Chuan Wang, Hwai-Ting Lin, Yi-Ju Lee, Hsien-Fu Yu, Sin-Ru Wu, Muhammad Usama Qama. Recovery of BDNF and CB1R in the Prefrontal Cortex Underlying Improvement of Working Memory in Prenatal DEHP-Exposed Male Rats after Aerobic Exercise. International journal of molecular sciences. vol 21. issue 11. 2021-02-16. PMID:32485872. |
the expressions of bdnf, dopamine d1 receptor (d1r), cannabinoid receptor 1 (cb1r), and fatty acid amide hydrolase (faah) in the prefrontal cortex were detected by western blot. |
2021-02-16 |
2023-08-13 |
rat |
| Dean-Chuan Wang, Hwai-Ting Lin, Yi-Ju Lee, Hsien-Fu Yu, Sin-Ru Wu, Muhammad Usama Qama. Recovery of BDNF and CB1R in the Prefrontal Cortex Underlying Improvement of Working Memory in Prenatal DEHP-Exposed Male Rats after Aerobic Exercise. International journal of molecular sciences. vol 21. issue 11. 2021-02-16. PMID:32485872. |
importantly, aerobic exercise during childhood-adolescence prevented the impairment of working memory in the dehp-exposed rats by recovering the bdnf and cb1r expressions in the prefrontal cortex. |
2021-02-16 |
2023-08-13 |
rat |