| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roberta Ströher Toledo, Dirson João Stein, Paulo Roberto Stefani Sanches, Lisiane Santos da Silva, Helouise Richardt Medeiros, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. rTMS induces analgesia and modulates neuroinflammation and neuroplasticity in neuropathic pain model rats. Brain research. vol 1762. 2021-08-11. PMID:33737061. |
biochemical assays to assess the levels of brain-derived neurotrophic factor (bdnf), tumor necrosis factor-alpha (tnf-α), and interleukin (il)-10, were performed in the prefrontal cortex (pfc) and spinal cord tissue homogenates. |
2021-08-11 |
2023-08-13 |
rat |
| Roberta Ströher Toledo, Dirson João Stein, Paulo Roberto Stefani Sanches, Lisiane Santos da Silva, Helouise Richardt Medeiros, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. rTMS induces analgesia and modulates neuroinflammation and neuroplasticity in neuropathic pain model rats. Brain research. vol 1762. 2021-08-11. PMID:33737061. |
moreover, rtms increased the levels of bdnf, tnf-α, and il-10 in the pfc. |
2021-08-11 |
2023-08-13 |
rat |
| Nandkishor Kotagale, Sandip Rahangdale, Anjali Borkar, Kundan Singh, Abhilasha Ikhar, Nikita Takale, Milind Umekar, Brijesh Taksand. Possible involvement of agmatine in neuropharmacological actions of metformin in diabetic mice. European journal of pharmacology. vol 907. 2021-08-03. PMID:34129880. |
after 28 days, stz treated mice exhibited memory impairment in radial arm maze, depression-like behavior in forced swim test and anxiety-like behavior in elevated plus maze along with increased expression of pro-inflammatory cytokines like tnf-α, il-1β, il-6, il-10 also, reduced agmatine and bdnf levels in the hippocampus and prefrontal cortex compared to the control animals. |
2021-08-03 |
2023-08-13 |
mouse |
| Nandkishor Kotagale, Sandip Rahangdale, Anjali Borkar, Kundan Singh, Abhilasha Ikhar, Nikita Takale, Milind Umekar, Brijesh Taksand. Possible involvement of agmatine in neuropharmacological actions of metformin in diabetic mice. European journal of pharmacology. vol 907. 2021-08-03. PMID:34129880. |
it also reduced neuro-inflammatory markers and increased agmatine and bdnf levels in the hippocampus and prefrontal cortex. |
2021-08-03 |
2023-08-13 |
mouse |
| Lucia Recinella, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Serena Veschi, Alessandro Cama, Guya Diletta Marconi, Francesca Diomede, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V Schally, Luigi Brunetti, Sheila Leon. Effects of growth hormone-releasing hormone receptor antagonist MIA-602 in mice with emotional disorders: a potential treatment for PTSD. Molecular psychiatry. 2021-07-31. PMID:34331008. |
the beneficial effect of mia-602 on inflammatory and oxidative status and synaptogenesis resulting in anxiolytic and antidepressant-like effects could be related by increases of nuclear factor erythroid 2-related factor 2 (nrf2) and of brain-derived neurotrophic factor (bdnf) signaling pathways in the hippocampus and prefrontal cortex. |
2021-07-31 |
2023-08-13 |
mouse |
| Daymara Mercerón-Martínez, William Almaguer-Melian, Esteban Alberti-Amador, Rául Calderón-Peña, Jorge A Bergad. Amygdala stimulation ameliorates memory impairments and promotes c-Fos activity in fimbria-fornix-lesioned rats. Synapse (New York, N.Y.). vol 74. issue 12. 2021-07-27. PMID:32621298. |
the mechanisms for this improvement involve early gene expression and synthesis of bdnf, map-2, and gap43 in the hippocampus and prefrontal cortex. |
2021-07-27 |
2023-08-13 |
rat |
| Basem H Elesawy, Walaa F Alsanie, Mubarak Ali Algahtany, Jawaher M Al-Ashkhari, Aya K Alyarobi, Hussein F Sak. Whole and refined grains change behavior and reduce brain derived neurotrophic factor and neurotrophin-3 in rats. Journal of food biochemistry. 2021-07-19. PMID:34278588. |
the rats on a diet of whole and refined grains had low bdnf, nt-3, norepinephrine, dopamine and serotonin significantly (p < .01) in both the hippocampus and prefrontal cortex as compared to control rats. |
2021-07-19 |
2023-08-13 |
rat |
| Jie Tong, Jie Zhang, Ying Jin, Weiqing Liu, Hao Wang, Ying Huang, Dianhong Shi, Minhuan Zhu, Na Zhu, Tingting Zhang, Xirong Su. Impact of Repetitive Transcranial Magnetic Stimulation (rTMS) on Theory of Mind and Executive Function in Major Depressive Disorder and Its Correlation with Brain-Derived Neurotrophic Factor (BDNF): A Randomized, Double-Blind, Sham-Controlled Trial. Brain sciences. vol 11. issue 6. 2021-07-05. PMID:34207545. |
we aimed to evaluate the efficacy of 20 sessions of a 10 hz unilateral rtms intervention over the left dorsolateral prefrontal cortex (dlpfc) in improving tom and ef in patients with mdd and its correlation with bdnf. |
2021-07-05 |
2023-08-13 |
Not clear |
| Itsuka Kamimura, Ryou Kaneko, Hidetoshi Morita, Kazutaka Mogi, Takefumi Kikusu. Microbial colonization history modulates anxiety-like and complex social behavior in mice. Neuroscience research. vol 168. 2021-06-29. PMID:32017965. |
gf mice also had decreased brain-derived neurotrophic factor (bdnf) and increased Δfosb mrna in the prefrontal cortex compared to spf mice. |
2021-06-29 |
2023-08-13 |
mouse |
| Amanda Della Giustina, Mariana Pereira de Souza Goldim, Lucinéia Gainski Danielski, Leandro Garbossa, Aloir Neri Oliveira Junior, Thainá Cidreira, Taís Denicol, Sandra Bonfante, Naiana da Rosa, Jucélia Jeremias Fortunato, Juliete Palandi, Bruna Hoffmann de Oliveira, Daniel Fernandes Martins, Franciane Bobinski, Michelle Garcez, Tatiani Bellettini-Santos, Josiane Budni, Gabriela Colpo, Giselli Scaini, Vijayasree V Giridharan, Tatiana Barichello, Fabricia Petronilh. Lipoic Acid and Fish Oil Combination Potentiates Neuroinflammation and Oxidative Stress Regulation and Prevents Cognitive Decline of Rats After Sepsis. Molecular neurobiology. vol 57. issue 11. 2021-06-29. PMID:32743736. |
the combination enhanced catalase activity in the prefrontal cortex and hippocampus, elevated bdnf levels in all structures, and prevented behavioral impairment. |
2021-06-29 |
2023-08-13 |
rat |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
here, we review the literature demonstrating that exposure to stress and depression decreases bdnf expression in the hippocampus and pfc and conversely that antidepressant treatment can up-regulate bdnf in the adult brain and reverse the effects of stress. |
2021-06-28 |
2023-08-13 |
Not clear |
| Kenichi Fukumoto, Manoela V Fogaça, Rong-Jian Liu, Catharine H Duman, Xiao-Yuan Li, Shigeyuki Chaki, Ronald S Duma. Medial PFC AMPA receptor and BDNF signaling are required for the rapid and sustained antidepressant-like effects of 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:32396921. |
medial pfc ampa receptor and bdnf signaling are required for the rapid and sustained antidepressant-like effects of 5-ht we previously reported that the serotonergic system is important for the antidepressant-like effects of ketamine, a non-competitive n-methyl-d-aspartate receptor antagonist, which produces rapid and long-lasting antidepressant effects in patients with major depressive disorder (mdd). |
2021-06-23 |
2023-08-13 |
Not clear |
| Fu Li, Haitao Xiang, Jiashu Lu, Zhuo Chen, Chao Huang, Xiaomei Yua. Lycopene ameliorates PTSD-like behaviors in mice and rebalances the neuroinflammatory response and oxidative stress in the brain. Physiology & behavior. vol 224. 2021-06-21. PMID:32592701. |
lycopene treatment (20 mg/kg, 12 days) also suppressed the sps-induced decrease in brain derived neurotrophic factor (bdnf) levels in the hippocampus and prefrontal cortex in mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Lianghui Ni, Yanling Xu, Sixuan Dong, Yujia Kong, Hong Wang, Guohua Lu, Yanyu Wang, Qi Li, Changjiang Li, Zhongde Du, Hongwei Sun, Lin Su. The potential role of the HCN1 ion channel and BDNF-mTOR signaling pathways and synaptic transmission in the alleviation of PTSD. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32198387. |
a series of behavioral tests and biochemical assessments of certain proteins (hcn1, bdnf, and pmtor) and synaptic ultrastructure in the prefrontal cortex (pfc) and hippocampus (hip) were then conducted. |
2021-06-18 |
2023-08-13 |
rat |
| Wei Sun, Yang Yang, Xiao Chen, Yan Cheng, Xiaolian Li, Lei A. Light Promotes Neural Correlates of Fear Memory via Enhancing Brain-Derived Neurotrophic Factor (BDNF) Expression in the Prelimbic Cortex. ACS chemical neuroscience. vol 12. issue 10. 2021-06-18. PMID:33961393. |
furthermore, light exposure elevated the training-induced brain-derived neurotrophic factor (bdnf) expression in the prelimbic, but not infralimbic, subregion of the pfc. |
2021-06-18 |
2023-08-13 |
rat |
| Seren Gülşen Gürgen, Gülce Naz Yazıcı, Ceyhun Gözükara, Ceyda Kabaroğlu, Ece Onu. Metoclopramide use to induce lactation can alter DRD2 and BDNF in the prefrontal cortex of offspring. Journal of chemical neuroanatomy. vol 109. 2021-06-14. PMID:32599253. |
metoclopramide use to induce lactation can alter drd2 and bdnf in the prefrontal cortex of offspring. |
2021-06-14 |
2023-08-13 |
rat |
| Seren Gülşen Gürgen, Gülce Naz Yazıcı, Ceyhun Gözükara, Ceyda Kabaroğlu, Ece Onu. Metoclopramide use to induce lactation can alter DRD2 and BDNF in the prefrontal cortex of offspring. Journal of chemical neuroanatomy. vol 109. 2021-06-14. PMID:32599253. |
since high-dose metoclopramide caused a decrease in drd2 expression in the external pyramidal layer in the prefrontal cortex, and since both high and low doses reduced bdnf expression, care needs to be taken with the use of metoclopramide in the lactation period due to the possibility of extrapyramidal reactions in offsprings. |
2021-06-14 |
2023-08-13 |
rat |
| Ricardo Augusto Leoni De Sousa, Isabella Rocha-Dias, Lucas Renan Sena de Oliveira, Alex Cleber Improta-Caria, Renato Sobral Monteiro-Junior, Ricardo Cardoso Cassilha. Molecular mechanisms of physical exercise on depression in the elderly: a systematic review. Molecular biology reports. vol 48. issue 4. 2021-06-09. PMID:33864590. |
physical exercise also increases expression of bdnf and its receptor, trkb, in the hippocampus and prefrontal cortex leading to upstream of erk and inhibiting depressive-like behavior. |
2021-06-09 |
2023-08-13 |
Not clear |
| Afzal Misrani, Sidra Tabassum, Meng Wang, Jian Chen, Li Yang, Cheng Lon. Citalopram prevents sleep-deprivation-induced reduction in CaMKII-CREB-BDNF signaling in mouse prefrontal cortex. Brain research bulletin. vol 155. 2021-06-03. PMID:31743748. |
we found that 24 h sd causes a marked reduction in the levels of phosphorylated calcium/calmodulin kinase ii (pcamkii), phosphorylated cyclic amp-responsive element binding protein (pcreb) and brain-derived neurotrophic factor (bdnf) in mouse pfc. |
2021-06-03 |
2023-08-13 |
mouse |
| Alaa M Hammad, Ghadeer M S Swiss, F Scott Hall, Suhair Hikmat, Youssef Sari, T M Al-Qirim, H A Amaw. Ceftriaxone Reduces Waterpipe Tobacco Smoke Withdrawal-induced Anxiety in rats via Modulating the Expression of TNF-α/NFĸB, Nrf2, and GLT-1. Neuroscience. vol 463. 2021-05-19. PMID:33836247. |
wts exposure increased the relative mrna levels for nuclear factor ĸb (nfĸb), tumor necrosis factor-α (tnf-α), and brain-derived neurotrophic factor (bdnf) in the pfc, nac and vta, and ceftriaxone treatment reversed these effects. |
2021-05-19 |
2023-08-13 |
rat |