| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G S B Viana, E M do Vale, A R A de Araujo, N C Coelho, S M Andrade, R O da Costa, P E A de Aquino, C N S de Sousa, I S de Medeiros, S M M de Vasconcelos, K R T Neve. Rapid and long-lasting antidepressant-like effects of ketamine and their relationship with the expression of brain enzymes, BDNF, and astrocytes. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 54. issue 2. 2021-02-02. PMID:33331415. |
increases in bdnf immunostaining were demonstrated in the pfc, dg, ca1, and ca3 areas at d1 and d30 time-points. |
2021-02-02 |
2023-08-13 |
mouse |
| Azadeh Shahroodi, Fatemeh Mohammadi, Abbas Ali Vafaei, Hossein Miladi-Gorji, Ahmad Reza Bandegi, Ali Rashidy-Pou. Impact of different intensities of forced exercise on deficits of spatial and aversive memory, anxiety-like behavior, and hippocampal BDNF during morphine abstinence period in male rats. Metabolic brain disease. vol 35. issue 1. 2021-01-29. PMID:31773433. |
thus, the current work examined the effects of different loads of forced exercise on cognition functions, anxiety behavior and bdnf changes in the hippocampus, and prefrontal cortex (pfc), and also serum levels of bdnf and corticosterone during the abstinent period in male rats. |
2021-01-29 |
2023-08-13 |
rat |
| Azadeh Shahroodi, Fatemeh Mohammadi, Abbas Ali Vafaei, Hossein Miladi-Gorji, Ahmad Reza Bandegi, Ali Rashidy-Pou. Impact of different intensities of forced exercise on deficits of spatial and aversive memory, anxiety-like behavior, and hippocampal BDNF during morphine abstinence period in male rats. Metabolic brain disease. vol 35. issue 1. 2021-01-29. PMID:31773433. |
in experiment 2, cognitive functions using t-maze alteration and passive avoidance tasks were tested, which accompanied by bdnf measurements in the hippocampus and pfc. |
2021-01-29 |
2023-08-13 |
rat |
| Azadeh Shahroodi, Fatemeh Mohammadi, Abbas Ali Vafaei, Hossein Miladi-Gorji, Ahmad Reza Bandegi, Ali Rashidy-Pou. Impact of different intensities of forced exercise on deficits of spatial and aversive memory, anxiety-like behavior, and hippocampal BDNF during morphine abstinence period in male rats. Metabolic brain disease. vol 35. issue 1. 2021-01-29. PMID:31773433. |
they also exhibited impaired t-maze alternation performance and passive avoidance memory, and a decline in hippocampal bdnf, but not pfc. |
2021-01-29 |
2023-08-13 |
rat |
| Rodrigo Moreno Klein, Camila Rigobello, Camila Borecki Vidigal, Kawane Fabrício Moura, Décio Sabbatini Barbosa, Daniela Cristina Ceccatto Gerardin, Graziela Scalianti Ceravolo, Estefânia Gastaldello Moreir. Gestational exposure to paracetamol in rats induces neurofunctional alterations in the progeny. Neurotoxicology and teratology. vol 77. 2021-01-25. PMID:31644948. |
moreover, lipid hidroperoxide (looh), reduced glutathione (gsh) and brain derived neurotrophic factor (bdnf) levels were quantified in prefrontal cortex and hippocampus of 22-days-old rats. |
2021-01-25 |
2023-08-13 |
rat |
| Rodrigo Moreno Klein, Camila Rigobello, Camila Borecki Vidigal, Kawane Fabrício Moura, Décio Sabbatini Barbosa, Daniela Cristina Ceccatto Gerardin, Graziela Scalianti Ceravolo, Estefânia Gastaldello Moreir. Gestational exposure to paracetamol in rats induces neurofunctional alterations in the progeny. Neurotoxicology and teratology. vol 77. 2021-01-25. PMID:31644948. |
no alterations were observed in looh, gsh or bdnf levels in the prefrontal cortex or hippocampus. |
2021-01-25 |
2023-08-13 |
rat |
| Drielly Florentino, Amanda Della Giustina, Mariana Pereira de Souza Goldim, Lucineia Gainski Danielski, Aloir Neri de Oliveira Junior, Larissa Joaquim, Sandra Bonfante, Erica Biehl, Naiana da Rosa, Deisy Fernandes, Fernanda Frederico Gava, Monique Michels, Jucelia Jeremias Fortunato, Gislaine Zilli Réus, Samira S Valvassori, Joao Quevedo, Felipe Dal-Pizzol, Tatiana Barichello, Fabricia Petronilh. Early life neuroimmune challenge protects the brain after sepsis in adult rats. Neurochemistry international. vol 135. 2021-01-25. PMID:32126248. |
wistar rats were divided in saline+sham, lps+sham, saline+clp and lps+clp groups to determine cytokine levels and nitrite/nitrate concentration in cerebrospinal fluid (csf); oxidative damage, activity of antioxidant enzymes (superoxide dismutase-sod and catalase-cat); blood brain barrier (bbb) permeability; myeloperoxidase (mpo) and epigenetic enzymes activities in the hippocampus and prefrontal cortex (at 24 h after clp) and cognitive function, survival and brain-derived neurotrophic factor (bdnf) level (at ten days after clp). |
2021-01-25 |
2023-08-13 |
rat |
| Paola Brivio, Giulia Sbrini, Marco Andrea Riva, Francesca Calabres. Acute Stress Induces Cognitive Improvement in the Novel Object Recognition Task by Transiently Modulating Bdnf in the Prefrontal Cortex of Male Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31960229. |
acute stress induces cognitive improvement in the novel object recognition task by transiently modulating bdnf in the prefrontal cortex of male rats. |
2021-01-22 |
2023-08-13 |
rat |
| Paola Brivio, Giulia Sbrini, Marco Andrea Riva, Francesca Calabres. Acute Stress Induces Cognitive Improvement in the Novel Object Recognition Task by Transiently Modulating Bdnf in the Prefrontal Cortex of Male Rats. Cellular and molecular neurobiology. vol 40. issue 6. 2021-01-22. PMID:31960229. |
we found that acute restraint stress up-regulated total bdnf expression 1 h post stress specifically in rat prefrontal cortex, an effect that was sustained by the increase of bdnf isoform iv as well as by the pool of bdnf transcripts with long 3'utr. |
2021-01-22 |
2023-08-13 |
rat |
| Eliza C B Jaeger, L Erin Miller, Emily C Goins, Chloe E Super, Christina U Chyr, John W Lower, Lauren S Honican, Daryl E Morrison, Rajan A Ramdev, Mark D Spritze. Testosterone replacement causes dose-dependent improvements in spatial memory among aged male rats. Psychoneuroendocrinology. vol 113. 2021-01-19. PMID:31901624. |
brain tissue (prefrontal cortex, hippocampus, and striatum) was collected from all subjects to assay bdnf. |
2021-01-19 |
2023-08-13 |
human |
| Seyed Ahmad Salehzadeh, Ali Mohammadian, Fatemeh Salim. Effect of chronic methamphetamine injection on levels of BDNF mRNA and its CpG island methylation in prefrontal cortex of rats. Asian journal of psychiatry. vol 48. 2021-01-11. PMID:31830601. |
effect of chronic methamphetamine injection on levels of bdnf mrna and its cpg island methylation in prefrontal cortex of rats. |
2021-01-11 |
2023-08-13 |
rat |
| Satoshi Deyama, Ronald S Duma. Neurotrophic mechanisms underlying the rapid and sustained antidepressant actions of ketamine. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31830487. |
clinical and preclinical studies have demonstrated that depression, one of the most common psychiatric illnesses, is associated with reduced levels of neurotrophic factors, including brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf), contributing to neuronal atrophy in the prefrontal cortex (pfc) and hippocampus, and reduced hippocampal adult neurogenesis. |
2020-12-31 |
2023-08-13 |
Not clear |
| Satoshi Deyama, Ronald S Duma. Neurotrophic mechanisms underlying the rapid and sustained antidepressant actions of ketamine. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31830487. |
rodent studies also demonstrate that ketamine rapidly increases bdnf and vegf release and/or expression in the medial pfc (mpfc) and hippocampus, leading to increase in the number and function of spine synapses in the mpfc and enhancement of hippocampal neurogenesis. |
2020-12-31 |
2023-08-13 |
Not clear |
| Yunfei Tan, Yuko Fujita, Youge Qu, Lijia Chang, Yaoyu Pu, Siming Wang, Xingming Wang, Kenji Hashimot. Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine: Role of BDNF-TrkB signaling. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31866390. |
western blot analysis showed decreased levels of brain-derived neurotrophic factor (bdnf) and decreased ratio of phosphorylated-trkb (p-trkb) to trkb in the prefrontal cortex (pfc) and hippocampus of pcp-treated mice. |
2020-12-31 |
2023-08-13 |
mouse |
| Yunfei Tan, Yuko Fujita, Youge Qu, Lijia Chang, Yaoyu Pu, Siming Wang, Xingming Wang, Kenji Hashimot. Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent repeated intermittent administration of (R)-ketamine, but not (S)-ketamine: Role of BDNF-TrkB signaling. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31866390. |
furthermore, pcp-induced reduction of bdnf and p-trkb/trkb ratio in the pfc and hippocampus of pcp-treated mice was ameliorated by subsequent intermittent administration of (r)-ketamine. |
2020-12-31 |
2023-08-13 |
mouse |
| Jariya Umka Welbat, Salinee Naewla, Wanassanan Pannangrong, Apiwat Sirichoat, Anusara Aranarochana, Peter Wigmor. Neuroprotective effects of hesperidin against methotrexate-induced changes in neurogenesis and oxidative stress in the adult rat. Biochemical pharmacology. vol 178. 2020-12-07. PMID:32522593. |
treatment with mtx also increased malondialdehyde (mda) in both the hippocampus and prefrontal cortex and decreased levels of brain-derived neurotropic factor (bdnf) and nuclear factor erythroid 2-related factor 2 (nrf2) in the hippocampus and prefrontal cortex. |
2020-12-07 |
2023-08-13 |
rat |
| Veronica Begni, Alice Sanson, Natascha Pfeiffer, Christiane Brandwein, Dragos Inta, Steven R Talbot, Marco Andrea Riva, Peter Gass, Anne Stephanie Mallie. Social isolation in rats: Effects on animal welfare and molecular markers for neuroplasticity. PloS one. vol 15. issue 10. 2020-12-04. PMID:33108362. |
isolation strongly affected markers of neuroplasticity in the prefrontal cortex independent of timing: mrna levels of arc, bdnf and the pool of bdnf transcripts with the 3' long utr were reduced in all groups. |
2020-12-04 |
2023-08-13 |
human |
| Ning Jiang, Haixia Wang, Jingwei Lv, Qiong Wang, Cong Lu, Yujiao Li, Xinmin Li. Dammarane sapogenins attenuates stress-induced anxiety-like behaviors by upregulating ERK/CREB/BDNF pathways. Phytotherapy research : PTR. vol 34. issue 10. 2020-11-30. PMID:32431006. |
treatment with ds significantly upregulated bdnf (brain-derived neurotrophic factor), p-creb/creb and p-erk1/2/erk1/2 protein expression in the hippocampus and prefrontal cortex of csds mice. |
2020-11-30 |
2023-08-13 |
mouse |
| Alex J T Yang, Scott Frendo-Cumbo, Rebecca E K MacPherso. Resveratrol and Metformin Recover Prefrontal Cortex AMPK Activation in Diet-Induced Obese Mice but Reduce BDNF and Synaptophysin Protein Content. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31450493. |
resveratrol and metformin recover prefrontal cortex ampk activation in diet-induced obese mice but reduce bdnf and synaptophysin protein content. |
2020-11-05 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
elevated thyroid peroxidase antibody increases risk of post-partum depression by decreasing prefrontal cortex bdnf and 5-ht levels in mice. |
2020-10-01 |
2023-08-13 |
mouse |