| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
furthermore, in the prefrontal cortex, the mrna and protein expression levels of brain-derived neurotrophic factor (bdnf) were measured, serotonin (5-ht) levels were measured by ultra-high-performance liquid chromatography-tandem mass-spectrometry (uhplc-ms/ms), and total thyroxine (tt4) levels were determined by elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
compared with the controls, the mice immunized with mtpo-ad displayed depressive behaviors, with a significantly lower sucrose preference (sp) at the 12-h time point and a longer immobility time in the fst and tst, which were accompanied by a lower expression of bdnf and 5-ht but no change in the tt4 concentration in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Yingying Zhou, Xinyi Wang, Yuhang Zhao, Aihua Liu, Tong Zhao, Yuanyuan Zhang, Zhongyan Shan, Weiping Ten. Elevated Thyroid Peroxidase Antibody Increases Risk of Post-partum Depression by Decreasing Prefrontal Cortex BDNF and 5-HT Levels in Mice. Frontiers in cellular neuroscience. vol 10. 2020-10-01. PMID:28119573. |
together, these findings suggest that elevated tpoab may increase the risk of subsequent ppd and decrease the concentration of bdnf and 5-ht in the prefrontal cortex. |
2020-10-01 |
2023-08-13 |
mouse |
| Juliana C de Souza Custódio, Cleciane W Martins, Marcelo D M V Lugon, Lívia C de Melo Rodrigues, Suely G de Figueiredo, Ester M Nakamura-Palacio. Prefrontal BDNF Levels After Anodal Epidural Direct Current Stimulation in Rats. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30050442. |
this study measured levels of brain-derived neurotrophic factor (bdnf) in the prefrontal cortex (pfc) after single (s) and repetitive (r) anodal epidural dc stimulation (edcs) over the left medial prefrontal cortex (mpfc). |
2020-10-01 |
2023-08-13 |
rat |
| Robyn Jane McQuaid, Roderick Dunn, Shlomit Jacobson-Pick, Hymie Anisman, Marie-Claude Aude. Post-weaning Environmental Enrichment in Male CD-1 Mice: Impact on Social Behaviors, Corticosterone Levels and Prefrontal Cytokine Expression in Adulthood. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30065637. |
ninety minutes following the behavioral tests, mice were sacrificed and a blood sample and the prefrontal cortex (pfc) were collected for the determination of plasma corticosterone levels as well as cytokine and bdnf mrna expression. |
2020-10-01 |
2023-08-13 |
mouse |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
the plasma concentrations of c-reactive protein (crp) and interleukin-6 (il-6) were measured, and the protein expressions of brain-derived neurotrophic factor (bdnf), copine 6, and synaptic plasticity markers in the hippocampus and the pfc were also detected. |
2020-10-01 |
2023-08-13 |
rat |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
moreover, the protein expressions of bdnf, copine 6, and synapsin i were decreased in both the hippocampus and the pfc of cums rats, and the protein expression of synaptotagmin i was decreased in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Yin-Xiu Han, Chen Tao, Xin-Ran Gao, Le-le Wang, Fu-Hao Jiang, Chong Wang, Ke Fang, Xing-Xing Chen, Zheng Chen, Jin-Fang G. BDNF-Related Imbalance of Copine 6 and Synaptic Plasticity Markers Couples With Depression-Like Behavior and Immune Activation in CUMS Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30429764. |
furthermore, pearson's test revealed a potential relationship between the depression-like behavior, the plasma crp concentration, and the protein expressions of bdnf, copine 6, synapsin i, or synaptotagmin i in the hippocampus or the pfc. |
2020-10-01 |
2023-08-13 |
rat |
| Zheng Gu, Liujie Chu, Yaqiong Ha. Therapeutic effect of resveratrol on mice with depression. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30936978. |
dopamine (da) and serotoni (5-ht) and the level of brain-derived nerve growth factor (bdnf) in the prefrontal cortex of each group were analyzed by elisa. |
2020-10-01 |
2023-08-13 |
mouse |
| Hang Xu, Yu Zhang, Fan Zhang, San-Na Yuan, Feng Shao, Weiwen Wan. Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence. Frontiers in molecular neuroscience. vol 9. 2020-09-30. PMID:27757074. |
in this study, we initially examined the effects of adolescent social stress on cognitive flexibility and pfc bdnf expression within a week after the last stress exposure and 6 weeks later during adulthood. |
2020-09-30 |
2023-08-13 |
mouse |
| Hang Xu, Yu Zhang, Fan Zhang, San-Na Yuan, Feng Shao, Weiwen Wan. Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence. Frontiers in molecular neuroscience. vol 9. 2020-09-30. PMID:27757074. |
levels of bdnf mrna and protein in the pfc were examined after behavioral testing. |
2020-09-30 |
2023-08-13 |
mouse |
| Hang Xu, Yu Zhang, Fan Zhang, San-Na Yuan, Feng Shao, Weiwen Wan. Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence. Frontiers in molecular neuroscience. vol 9. 2020-09-30. PMID:27757074. |
consistent with the cognitive alterations, adolescent stress induced dynamic alterations in bdnf expression in the medial pfc (mpfc), with a transient increase observed shortly after the stress, followed by a decrease 6 weeks later during adulthood. |
2020-09-30 |
2023-08-13 |
mouse |
| Xian-Zhe Dong, Dong-Xiao Wang, Bing-Ying Yu, Ping Liu, Yuan H. Kai-Xin-San, a traditional Chinese medicine formulation, exerts antidepressive and neuroprotective effects by promoting pCREB upstream pathways. Experimental and therapeutic medicine. vol 12. issue 5. 2020-09-30. PMID:27882154. |
in kxs rats, increased protein expression levels of pcreb, bdnf and tyrosine receptor kinase b (trkb) were observed in the hippocampus and prefrontal cortex, compared with the cms model group. |
2020-09-30 |
2023-08-13 |
rat |
| Paola Brivio, Giulia Sbrini, Polina Peeva, Mihail Todiras, Michael Bader, Natalia Alenina, Francesca Calabres. TPH2 Deficiency Influences Neuroplastic Mechanisms and Alters the Response to an Acute Stress in a Sex Specific Manner. Frontiers in molecular neuroscience. vol 11. 2020-09-30. PMID:30425618. |
we found a significant increase, in both gene and protein expression, of the neurotrophin brain-derived neurotrophic factor (bdnf), in the prefrontal cortex (pfc) of adult tph2-deficient (tph2 |
2020-09-30 |
2023-08-13 |
rat |
| Rafaela Carneiro Cordeiro, Adriano José Maia Chaves Filho, Nayana Soares Gomes, Viviane de Sousa Tomaz, Camila Dantas Medeiros, Ana Isabelle de Góis Queiroz, Michael Maes, Danielle S Macedo, Andre F Carvalh. Leptin Prevents Lipopolysaccharide-Induced Depressive-Like Behaviors in Mice: Involvement of Dopamine Receptors. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:30949073. |
in neurochemical analysis, leptin restored lps-induced changes in il-1β levels in the pfc and striatum, and increased bdnf levels in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Paula M Q Bellozi, Renan Pelição, Matheus C Santos, Isabel V A Lima, Soraya W Saliba, Érica L M Vieira, Alline C Campos, Antônio L Teixeira, Antônio C P de Oliveira, Ester M Nakamura-Palacios, Lívia C M Rodrigue. URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats. Neuroscience letters. vol 711. 2020-09-28. PMID:31374324. |
the chronic binge alcohol administration increased the interferon (ifn)-γ and tumor necrosis factor (tnf)-α levels in the pfc and hippocampus and the interleukin (il)-10 and bdnf levels in the pfc, and these effects were prevented by urb597. |
2020-09-28 |
2023-08-13 |
rat |
| Ke Fang, Hua-Rong Li, Xing-Xing Chen, Xin-Ran Gao, Ling-Ling Huang, An-Qi Du, Chuan Jiang, Hua Li, Jin-Fang G. Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009956. |
results of western blot showed that the expression levels of bdnf, copine 6, p-trkb, and the triggering receptors expressed on myeloid cells (trem) 1 were decreased in both the hippocampus and the prefrontal cortex (pfc) of lps-challenged rats, while the expression of trem2 was increased. |
2020-09-28 |
2023-08-13 |
mouse |
| Weiwei Zhong, Yan Yuan, Xiaohuan Gu, Samuel In-Young Kim, Ryan Chin, Modupe Loye, Thomas A Dix, Ling Wei, Shan Ping Y. Neuropsychological Deficits Chronically Developed after Focal Ischemic Stroke and Beneficial Effects of Pharmacological Hypothermia in the Mouse. Aging and disease. vol 11. issue 1. 2020-09-28. PMID:32010477. |
altered neuronal plasticity such as suppressed long-term potentiation (ltp), reduced bdnf and oxytocin signaling, and disturbed dopamine synthesis/uptake were detected in the prefrontal cortex (pfc) during the chronic phase after stroke. |
2020-09-28 |
2023-08-13 |
mouse |
| Yuting Ke, Shizhong Bu, Hong Ma, Lei Gao, Yujia Cai, Yisheng Zhang, Wenhua Zho. Preventive and Therapeutic Effects of Astaxanthin on Depressive-Like Behaviors in High-Fat Diet and Streptozotocin-Treated Rats. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32082151. |
preventive or preventative plus therapeutic treatment with ast at doses of 15 or 25 mg/kg significantly increased the expression of perk, pakt, pcreb, and bdnf in the prefrontal cortex (pfc) in diabetic rats. |
2020-09-28 |
2023-08-13 |
rat |
| Sabrina Theresia Müller, Andreas Buchmann, Melanie Haynes, Carmen Ghisleni, Christopher Ritter, Ruth Tuura, Gregor Hasle. Negative association between left prefrontal GABA concentration and BDNF serum concentration in young adults. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32490241. |
we investigated the relationship between gaba concentration in the left dorsolateral prefrontal cortex (dlpfc) and bdnf concentration in the serum in a community-based sample of young subjects. |
2020-09-28 |
2023-08-13 |
human |