| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xuan Jiang, Tianxiang Gu, Yu Liu, Shilun Gao, Enyi Shi, Guangwei Zhan. Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass. Therapeutic hypothermia and temperature management. vol 9. issue 2. 2020-01-02. PMID:30036167. |
the levels of opioid receptor delta 1 (oprd1), mature brain-derived neurotrophic factor (m-bdnf), precursor of bdnf (pro-bdnf), trkb, grb2, erk, p-erk, p38, bcl-2, p75ntr, traf6, jnk, p53, bax, and caspase3 of the hippocampus were analyzed at 24 hours after surgery. |
2020-01-02 |
2023-08-13 |
rat |
| Matthew G Solomon, William C Griffin, Marcelo F Lopez, Howard C Becke. Brain Regional and Temporal Changes in BDNF mRNA and microRNA-206 Expression in Mice Exposed to Repeated Cycles of Chronic Intermittent Ethanol and Forced Swim Stress. Neuroscience. vol 406. 2020-01-02. PMID:30790666. |
the present study examined the effects of chronic ethanol and fss exposure, alone and in combination, on bdnf mrna expression in different brain regions, including mpfc, central amygdala (cea), and hippocampus (hpc). |
2020-01-02 |
2023-08-13 |
mouse |
| Marina Cefis, Anne Prigent-Tessier, Aurore Quirié, Nicolas Pernet, Christine Marie, Philippe Garnie. The effect of exercise on memory and BDNF signaling is dependent on intensity. Brain structure & function. vol 224. issue 6. 2020-01-02. PMID:31089854. |
expressions of bdnf, phosphorylated trkb receptors, synaptophysin (a marker of synaptogenesis), c-fos (a neuronal activity marker) and phosphorylated endothelial nitric oxide synthase (a cerebral blood flow marker) were measured in prefrontal cortex and hippocampus of different groups of rats. |
2020-01-02 |
2023-08-13 |
rat |
| Marina Cefis, Anne Prigent-Tessier, Aurore Quirié, Nicolas Pernet, Christine Marie, Philippe Garnie. The effect of exercise on memory and BDNF signaling is dependent on intensity. Brain structure & function. vol 224. issue 6. 2020-01-02. PMID:31089854. |
our data also revealed that bdnf pathway is dependent on intensity modality of exercise with a gradual effect in hippocampus whereas only the highest intensity leads to this pathway activation in prefrontal cortex. |
2020-01-02 |
2023-08-13 |
rat |
| Yoo Jin Shin, Yeon Tae Chun, Sun Woo Lim, Kang Luo, Yi Quan, Sheng Cui, Eun Jeong Ko, Byung Ha Chung, Jiyeong Lee, Seongno Hong, Mun Yong Lee, Hee Gyoo Kang, Chul Woo Yan. Influence of Tacrolimus on Depressive-Like Behavior in Diabetic Rats Through Brain-Derived Neurotrophic Factor Regulation in the Hippocampus. Neurotoxicity research. vol 36. issue 2. 2020-01-02. PMID:31201731. |
the aim of the present study was to investigate the influence of tacrolimus on brain-derived neurotrophic factor (bdnf), the critical protein for maintenance of neuronal functions, in the hippocampus in a diabetic condition. |
2020-01-02 |
2023-08-13 |
rat |
| Yoo Jin Shin, Yeon Tae Chun, Sun Woo Lim, Kang Luo, Yi Quan, Sheng Cui, Eun Jeong Ko, Byung Ha Chung, Jiyeong Lee, Seongno Hong, Mun Yong Lee, Hee Gyoo Kang, Chul Woo Yan. Influence of Tacrolimus on Depressive-Like Behavior in Diabetic Rats Through Brain-Derived Neurotrophic Factor Regulation in the Hippocampus. Neurotoxicity research. vol 36. issue 2. 2020-01-02. PMID:31201731. |
bdnf expression in the hippocampus was examined in the dentate gyrus (dg) and ca3 region using immunohistochemistry. |
2020-01-02 |
2023-08-13 |
rat |
| Yoo Jin Shin, Yeon Tae Chun, Sun Woo Lim, Kang Luo, Yi Quan, Sheng Cui, Eun Jeong Ko, Byung Ha Chung, Jiyeong Lee, Seongno Hong, Mun Yong Lee, Hee Gyoo Kang, Chul Woo Yan. Influence of Tacrolimus on Depressive-Like Behavior in Diabetic Rats Through Brain-Derived Neurotrophic Factor Regulation in the Hippocampus. Neurotoxicity research. vol 36. issue 2. 2020-01-02. PMID:31201731. |
these data suggest that tacrolimus treatment or a diabetic condition decreases bdnf expression in the hippocampus, and that tacrolimus treatment in the diabetic condition further injures the ca3 region of the hippocampus. |
2020-01-02 |
2023-08-13 |
rat |
| Xiang Li, Takahiro Inoue, Masataka Hayashi, Hiroshi Maejim. Exercise enhances the expression of brain-derived neurotrophic factor in the hippocampus accompanied by epigenetic alterations in senescence-accelerated mice prone 8. Neuroscience letters. vol 706. 2019-12-27. PMID:31108130. |
exercise increases the expression of brain-derived neurotrophic factor (bdnf) in the hippocampus and beneficially contributes to cognitive function and is accompanied by epigenetic changes. |
2019-12-27 |
2023-08-13 |
mouse |
| Xiang Li, Takahiro Inoue, Masataka Hayashi, Hiroshi Maejim. Exercise enhances the expression of brain-derived neurotrophic factor in the hippocampus accompanied by epigenetic alterations in senescence-accelerated mice prone 8. Neuroscience letters. vol 706. 2019-12-27. PMID:31108130. |
the objective of the present study was to assess the effect of an exercise regimen over a long period on the expression of bdnf, tropomyosin receptor kinase b (trkb) and p75, and the activity of hats and hdacs in the degenerative hippocampus. |
2019-12-27 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Qiong Wang, Cong Lu, Yu-Jie Yang, Hong Huang, Tian-Ji Xia, Guang-Hua Lv, Xin-Min Li. Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms. Phytotherapy research : PTR. vol 33. issue 10. 2019-12-26. PMID:31353678. |
additionally, western blot analysis revealed that csds exposure significantly downregulated bdnf, p-trkb/trkb, p-akt/akt, and p-mtor/mtor protein expression in the hippocampus. |
2019-12-26 |
2023-08-13 |
mouse |
| Liuli Li, Hao Li, Peng Qu, Mingyang Xiao, Guopei Zhang, Qianye Zhang, Yuan Cai, Cuihong Jin, Jinghua Yang, Shengwen Wu, Xiaobo L. An Antagonism Joint Action of Lead and Di-2-Ethylhexyl Phthalate Explains an Improved Ability of Learning and Memory after Combined Exposure in Weaning Rats. Biological trace element research. vol 191. issue 1. 2019-12-24. PMID:30523571. |
the content of dehydroepiandrosterone (dhea) in serum and the mrna level of brain-derived neurotrophic factor (bdnf) in the hippocampus showed a similar trend to the ability of learning and memory. |
2019-12-24 |
2023-08-13 |
rat |
| Alexandre Aparecido de Almeida, Sérgio Gomes da Silva, Glauber Menezes Lopim, Diego Vannucci Campos, Jansen Fernandes, Francisco Romero Cabral, Ricardo Mario Arid. Physical exercise alters the activation of downstream proteins related to BDNF-TrkB signaling in male Wistar rats with epilepsy. Journal of neuroscience research. vol 96. issue 5. 2019-12-23. PMID:29098710. |
we investigated the effects of aerobic exercise on hippocampal levels of brain-derived neurotrophic factor (bdnf), expression of its receptor tropomyosin receptor kinase b (trkb), and activation of intracellular proteins related to bdnf-trkb signaling in male wistar rats with pilocarpine-induced epilepsy. |
2019-12-23 |
2023-08-13 |
rat |
| L E Wearick-Silva, A D Sebben, Z S M Costa-Ferro, D R Marinowic, M L Nune. Undernourishment and recurrent seizures early in life impair Long-Term Potentiation and alter NMDAR and AMPAR expression in rat hippocampus. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 75. 2019-12-18. PMID:30940500. |
electrophysiological records of hippocampal slices were recorded and gene expression of nr1a, nr2a, nr2b, nr2c, nr2d and bdnf were investigated. |
2019-12-18 |
2023-08-13 |
rat |
| Hyo-Min Jang, Kyung-Eon Lee, Hae-Ji Lee, Dong-Hyun Ki. Immobilization stress-induced Escherichia coli causes anxiety by inducing NF-κB activation through gut microbiota disturbance. Scientific reports. vol 8. issue 1. 2019-12-13. PMID:30224732. |
exposure of mice to immobilization stress (is) led to anxiety-like behaviors, increased corticosterone and tumor necrosis factor-α levels in the blood, increased nuclear factor (nf)-κb activation and microglia/monocyte populations in the hippocampus, and suppressed brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2019-12-13 |
2023-08-13 |
mouse |
| Hyo-Min Jang, Kyung-Eon Lee, Hae-Ji Lee, Dong-Hyun Ki. Immobilization stress-induced Escherichia coli causes anxiety by inducing NF-κB activation through gut microbiota disturbance. Scientific reports. vol 8. issue 1. 2019-12-13. PMID:30224732. |
these treatments increased blood corticosterone and lps levels and anxiety-like behaviors, decreased bdnf expression, and induced nf-κb activation and microglia/monocyte populations in the hippocampus. |
2019-12-13 |
2023-08-13 |
mouse |
| F Biggio, M C Mostallino, G Talani, V Locci, R Mostallino, G Calandra, E Sanna, G Biggi. Social enrichment reverses the isolation-induced deficits of neuronal plasticity in the hippocampus of male rats. Neuropharmacology. vol 151. 2019-12-10. PMID:30935859. |
social enrichment restored the reduction of bdnf, ngf and arc gene expression in the whole hippocampus of social isolated rats. |
2019-12-10 |
2023-08-13 |
rat |
| Yusuke Nakagawa, Masahiro To, Juri Saruta, Yuko Yamamoto, Toshiharu Yamamoto, Tomoko Shimizu, Yohei Kamata, Masato Matsuo, Keiichi Tsukinok. Effect of social isolation stress on saliva BDNF in rat. Journal of oral science. vol 61. issue 4. 2019-11-29. PMID:31631095. |
the bdnf concentration was lower in the hippocampus, prefrontal cortex, blood, and saliva of the stress group than in those of the controls. |
2019-11-29 |
2023-08-13 |
rat |
| Takuya Ogawa, Hidemasa Okihara, Satoshi Kokai, Yasunori Abe, Uchima Koecklin Karin Harumi, Mio Makiguchi, Chiho Kato, Tadachika Yabushita, Makoto Michikawa, Takashi On. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels. Journal of neuroscience research. vol 96. issue 6. 2019-11-25. PMID:29392750. |
brain-derived neurotrophic factor (bdnf), tyrosine kinase receptor b (trkb), and phospho-p44/p42 mitogen-activated protein kinase (mapk) are known to contribute to hippocampal memory/learning. |
2019-11-25 |
2023-08-13 |
mouse |
| Takuya Ogawa, Hidemasa Okihara, Satoshi Kokai, Yasunori Abe, Uchima Koecklin Karin Harumi, Mio Makiguchi, Chiho Kato, Tadachika Yabushita, Makoto Michikawa, Takashi On. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels. Journal of neuroscience research. vol 96. issue 6. 2019-11-25. PMID:29392750. |
additionally, the uno group had higher hippocampal bdnf levels and serum corticosterone levels, lower hippocampal trkb and phospho-p44/p42 mapk levels, and reduced neuron numbers relative to controls. |
2019-11-25 |
2023-08-13 |
mouse |
| Michela Bistoletti, Valentina Caputi, Nicolò Baranzini, Nicoletta Marchesi, Viviana Filpa, Ilaria Marsilio, Silvia Cerantola, Genciana Terova, Andreina Baj, Annalisa Grimaldi, Alessia Pascale, Gianmario Frigo, Francesca Crema, Maria Cecilia Giron, Cristina Giaron. Antibiotic treatment-induced dysbiosis differently affects BDNF and TrkB expression in the brain and in the gut of juvenile mice. PloS one. vol 14. issue 2. 2019-11-21. PMID:30794676. |
bdnf and trkb protein levels were downregulated in the hippocampus and remained unchanged in the prefrontal cortex of abx-treated animals. |
2019-11-21 |
2023-08-13 |
mouse |