| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janine I Rossato, Maria Carolina Gonzalez, Andressa Radiske, Gênedy Apolinário, Sergio Conde-Ocazionez, Lia R Bevilaqua, Martín Cammarot. PKMζ Inhibition Disrupts Reconsolidation and Erases Object Recognition Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 10. 2020-03-23. PMID:30622166. |
the hippocampus is specifically engaged in reconsolidation to integrate new information into the original orm through a mechanism involving activation of brain-derived neurotrophic factor (bdnf) signaling and induction of ltp. |
2020-03-23 |
2023-08-13 |
rat |
| Janine I Rossato, Maria Carolina Gonzalez, Andressa Radiske, Gênedy Apolinário, Sergio Conde-Ocazionez, Lia R Bevilaqua, Martín Cammarot. PKMζ Inhibition Disrupts Reconsolidation and Erases Object Recognition Memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 10. 2020-03-23. PMID:30622166. |
our results also indicate that hippocampal pkmζ acts downstream of bdnf and controls ampar synaptic insertion to elicit reconsolidation and suggest that blocking pkmζ activity during this process deletes active orm. |
2020-03-23 |
2023-08-13 |
rat |
| Banafshe Esmaeilzade, Tayebe Artimani, Iraj Amiri, Rezvan Najafi, Siamak Shahidi, Marie Sabec, Parviz Farzadinia, Mohammadali Zare, Maria Zahiri, Sara Soleimani As. Dimethyloxalylglycine preconditioning enhances protective effects of bone marrow-derived mesenchymal stem cells in Aβ- induced Alzheimer disease. Physiology & behavior. vol 199. 2020-03-19. PMID:30500334. |
furthermore, we found an increased level of bdnf and total antioxidant capacity in the hippocampus of aβ-injected rats following transplantation of preconditioned relative to untreated mscs. |
2020-03-19 |
2023-08-13 |
rat |
| Lauretta El Hayek, Mohamad Khalifeh, Victor Zibara, Rawad Abi Assaad, Nancy Emmanuel, Nabil Karnib, Rim El-Ghandour, Patrick Nasrallah, Maria Bilen, Pascale Ibrahim, Joe Younes, Edwina Abou Haidar, Nour Barmo, Vanessa Jabre, Joseph S Stephan, Sama F Sleima. Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF). The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 13. 2020-03-18. PMID:30692222. |
lactate mediates the effects of exercise on learning and memory through sirt1-dependent activation of hippocampal brain-derived neurotrophic factor (bdnf). |
2020-03-18 |
2023-08-13 |
Not clear |
| Lauretta El Hayek, Mohamad Khalifeh, Victor Zibara, Rawad Abi Assaad, Nancy Emmanuel, Nabil Karnib, Rim El-Ghandour, Patrick Nasrallah, Maria Bilen, Pascale Ibrahim, Joe Younes, Edwina Abou Haidar, Nour Barmo, Vanessa Jabre, Joseph S Stephan, Sama F Sleima. Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF). The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 13. 2020-03-18. PMID:30692222. |
these effects depend on increases in hippocampal bdnf, a growth factor associated with cognitive improvement and the alleviation of depression symptoms. |
2020-03-18 |
2023-08-13 |
Not clear |
| Huan Li, Xingli Xue, Zhaoyang Li, Baolong Pan, Yanxia Hao, Qiao Ni. Aluminium-induced synaptic plasticity injury via the PHF8-H3K9me2-BDNF signalling pathway. Chemosphere. vol 244. 2020-03-17. PMID:31835052. |
with correlation analysis between the hippocampal standardised field excitatory postsynaptic potential (fepsp) amplitude and the expression of various proteins in the aluminium-exposed rat, the hippocampal standardised fepsp amplitude was positively correlated with the expression of hippocampal phf8 and bdnf proteins, and negatively correlated with the expression of hippocampal h3k9me2 protein. |
2020-03-17 |
2023-08-13 |
human |
| Lily Mohammadipoor-Ghasemabad, Mohammad Hossein Sangtarash, Vahid Sheibani, Hosein Ali Sasan, Saeed Esmaeili-Mahan. Hippocampal microRNA-191a-5p Regulates BDNF Expression and Shows Correlation with Cognitive Impairment Induced by Paradoxical Sleep Deprivation. Neuroscience. vol 414. 2020-03-13. PMID:31279826. |
hippocampal microrna-191a-5p regulates bdnf expression and shows correlation with cognitive impairment induced by paradoxical sleep deprivation. |
2020-03-13 |
2023-08-13 |
rat |
| Lily Mohammadipoor-Ghasemabad, Mohammad Hossein Sangtarash, Vahid Sheibani, Hosein Ali Sasan, Saeed Esmaeili-Mahan. Hippocampal microRNA-191a-5p Regulates BDNF Expression and Shows Correlation with Cognitive Impairment Induced by Paradoxical Sleep Deprivation. Neuroscience. vol 414. 2020-03-13. PMID:31279826. |
hippocampal mir-191a and mir-155 were significantly up-regulated (p ˂ .01) and bdnf down-regulated (p ˂ .05) in the psd group. |
2020-03-13 |
2023-08-13 |
rat |
| Lily Mohammadipoor-Ghasemabad, Mohammad Hossein Sangtarash, Vahid Sheibani, Hosein Ali Sasan, Saeed Esmaeili-Mahan. Hippocampal microRNA-191a-5p Regulates BDNF Expression and Shows Correlation with Cognitive Impairment Induced by Paradoxical Sleep Deprivation. Neuroscience. vol 414. 2020-03-13. PMID:31279826. |
hippocampal bdnf is probably one of the targets of mir-191a in sleep-deprived ovx rats. |
2020-03-13 |
2023-08-13 |
rat |
| E H Taniguti, Y S Ferreira, I J V Stupp, E B Fraga-Junior, D L Doneda, L Lopes, F Rios-Santos, E Lima, Z S Buss, G G Viola, S Vandresen-Filh. Atorvastatin prevents lipopolysaccharide-induced depressive-like behaviour in mice. Brain research bulletin. vol 146. 2020-03-10. PMID:30690060. |
atorvastatin (1 or 10 mg/kg/day) or fluoxetine treatment also prevented lps-induced increase in tnf-α and reduction of bdnf levels in the hippocampus and prefrontal cortex. |
2020-03-10 |
2023-08-13 |
mouse |
| Qi Ke, Rong Li, Li Cai, Sheng-Dong Wu, Chun-Mei L. Ro41-5253, a selective antagonist of retinoic acid receptor α, ameliorates chronic unpredictable mild stress-induced depressive-like behaviors in rats: Involvement of regulating HPA axis and improving hippocampal neuronal deficits. Brain research bulletin. vol 146. 2020-03-10. PMID:30711623. |
hpa axis activity, rarα expression in hypothalamic paraventricular nucleus (pvn) and hypothalamus, and protein levels of brain-derived neurotrophic factor (bdnf) and synapse-related proteins (psd95, syp, map2) in hippocampus were measured, respectively. |
2020-03-10 |
2023-08-13 |
rat |
| Qi Ke, Rong Li, Li Cai, Sheng-Dong Wu, Chun-Mei L. Ro41-5253, a selective antagonist of retinoic acid receptor α, ameliorates chronic unpredictable mild stress-induced depressive-like behaviors in rats: Involvement of regulating HPA axis and improving hippocampal neuronal deficits. Brain research bulletin. vol 146. 2020-03-10. PMID:30711623. |
in addition, ro41-5253 (1 mg/kg) treatment downregulated rarα protein expression in hypothalamic pvn and hypothalamus, and increased the protein levels of bdnf, psd95, syp and map2 in the hippocampus. |
2020-03-10 |
2023-08-13 |
rat |
| Raquell de Castro Chaves, Auriana Serra Vasconcelos Mallmann, Natália Ferreira Oliveira, Iris Cristina Maia Oliveira, Victor Celso Cavalcanti Capibaribe, Daniel Moreira Alves da Silva, Iardja Stéfane Lopes, José Tiago Valentim, Alyne Mara Rodrigues de Carvalho, Danielle Silveira Macêdo, Silvânia Maria Mendes Vasconcelos, Stanley Juan Chaves Gutierrez, José Maria Barbosa Filho, Francisca Cléa Florenço de Sous. Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. Pharmacology, biochemistry, and behavior. vol 180. 2020-03-10. PMID:30904544. |
the hippocampus was also removed for the determination of bdnf levels. |
2020-03-10 |
2023-08-13 |
mouse |
| Raquell de Castro Chaves, Auriana Serra Vasconcelos Mallmann, Natália Ferreira Oliveira, Iris Cristina Maia Oliveira, Victor Celso Cavalcanti Capibaribe, Daniel Moreira Alves da Silva, Iardja Stéfane Lopes, José Tiago Valentim, Alyne Mara Rodrigues de Carvalho, Danielle Silveira Macêdo, Silvânia Maria Mendes Vasconcelos, Stanley Juan Chaves Gutierrez, José Maria Barbosa Filho, Francisca Cléa Florenço de Sous. Reversal effect of Riparin IV in depression and anxiety caused by corticosterone chronic administration in mice. Pharmacology, biochemistry, and behavior. vol 180. 2020-03-10. PMID:30904544. |
corticosterone administration decreased bdnf levels and riparin iv could reestablish them, indicating that its antidepressant effect may be related to ability to ameliorate hippocampal neurogenesis. |
2020-03-10 |
2023-08-13 |
mouse |
| C Benatti, G Radighieri, S Alboni, J M C Blom, N Brunello, F Tascedd. Modulation of neuroplasticity-related targets following stress-induced acute escape deficit. Behavioural brain research. vol 364. 2020-03-09. PMID:30771367. |
total brain-derived neurotrophic factor (bdnf) was highly responsive in the pfc at 24-h after the escape test, while expression of bdnf transcript iv increased in the hippocampus of resistant animals 3 h post-test. |
2020-03-09 |
2023-08-13 |
rat |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
furthermore, cort administration differentially altered the expression of 11 bdnf mrna transcripts in the dorsal and ventral hippocampal dg. |
2020-03-09 |
2023-08-13 |
rat |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
our findings suggest an essential role for the mbdnf-probdnf system in regulating the hippocampus of cort-treated rats and present a new therapeutic mechanism for antidepressant treatments by targeting the bdnf mrna transcripts. |
2020-03-09 |
2023-08-13 |
rat |
| Ajeet Kumar, Shalini Dogra, Chandan Sona, Deepmala Umrao, Mamunur Rashid, Sandeep K Singh, Muhammad Wahajuddin, Prem N Yada. Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis. Psychoneuroendocrinology. vol 101. 2020-03-03. PMID:30458370. |
chronic ciproxifan treatment restored cus induced bdnf expression in the prefrontal cortex (pfc) and hippocampus. |
2020-03-03 |
2023-08-13 |
mouse |
| Iman Zangiabadi, Mohammad Reza Afarinesh, Ali Shamsara, Seyed Hasan Eftekhar-Vaghef. Movento effects on learning and hippocampal brain-derived neurotrophic factor protein of adult male rats. Environmental science and pollution research international. vol 26. issue 36. 2020-03-02. PMID:31734837. |
the changes in the concentration of hippocampal brain-derived neurotrophic factor (bdnf) proteins were evaluated, too. |
2020-03-02 |
2023-08-13 |
rat |
| Iman Zangiabadi, Mohammad Reza Afarinesh, Ali Shamsara, Seyed Hasan Eftekhar-Vaghef. Movento effects on learning and hippocampal brain-derived neurotrophic factor protein of adult male rats. Environmental science and pollution research international. vol 26. issue 36. 2020-03-02. PMID:31734837. |
the bdnf protein level of hippocampus also showed a significant decrease in the movento (1000 mg/kg) compared with the control group (p < 0.01) while the number of pancellular necrosis pyramidal ca1 cells increased significantly in the movento group (p < 0.001). |
2020-03-02 |
2023-08-13 |
rat |