| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masoumeh Sadeghinejad, Zahra Soltani, Mohammad Esmaeil Afzalpour, Mohammad Khaksari, Mohammad Pourranjba. What is the combined effect of intense intermittent exercise and Ginkgo biloba plant on the brain neurotrophic factors levels, and learning and memory in young rats? Pharmacological reports : PR. vol 71. issue 3. 2019-11-20. PMID:31009841. |
the present study was conducted to investigate the effect of intense intermittent exercise and ginkgo biloba on the hippocampal levels of brain-derived neurotrophic factor (bdnf) and neurotrophin-4 (nt-4) and also memory and learning in young rats. |
2019-11-20 |
2023-08-13 |
rat |
| S K Tahajjul Taufique, Abhilash Prabhat, Vinod Kuma. Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids. The European journal of neuroscience. vol 48. issue 9. 2019-11-14. PMID:30218624. |
concomitant reduction of immunoreactivity for dcx and bdnf suggested dlan-induced suppression of hippocampal neurogenesis and compromised neuronal health. |
2019-11-14 |
2023-08-13 |
Not clear |
| S K Tahajjul Taufique, Abhilash Prabhat, Vinod Kuma. Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids. The European journal of neuroscience. vol 48. issue 9. 2019-11-14. PMID:30218624. |
dlan also negatively influenced hippocampal expression of genes associated with depressive-like responses (bdnf, il-1β, tnfr1, nr4a2), but not of those associated with neuronal plasticity (egr1, creb, syngap, syn2, grin2a, grin2b), cellular oxidative stress (gst, sod3, cat1) and neuronal death (caspase2, caspase3, foxo3). |
2019-11-14 |
2023-08-13 |
Not clear |
| Stylianos Kosmidis, Alexandros Polyzos, Lucas Harvey, Mary Youssef, Christine A Denny, Alex Dranovsky, Eric R Kande. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell reports. vol 25. issue 4. 2019-11-14. PMID:30355501. |
by exploring how this protein regulates the genomic landscape of the hippocampal circuit, we find that rbap48 controls the expression of bdnf and gpr158 proteins, both critical components of osteocalcin (ocn) signaling in the mouse hippocampus. |
2019-11-14 |
2023-08-13 |
mouse |
| Sergio M G Solinas, Elke Edelmann, Volkmar Leßmann, Michele Miglior. A kinetic model for Brain-Derived Neurotrophic Factor mediated spike timing-dependent LTP. PLoS computational biology. vol 15. issue 4. 2019-11-12. PMID:31017891. |
the neurotrophin brain-derived neurotrophic factor (bdnf) is known to promote structural and functional synaptic plasticity in the hippocampus, the cerebral cortex, and many other brain areas. |
2019-11-12 |
2023-08-13 |
mouse |
| Asraa Faris Aldoghachi, Yin Sim Tor, Siti Zubaidah Redzun, Khairul Aiman Bin Lokman, Nurul Asyikin Abdul Razaq, Aishah Farhana Shahbudin, Ibrahim Mohamed Badamasi, Pike-See Cheah, Johnson Stanslas, Abhi Veerakumarasivam, Rozita Rosli, Normala Ibrahim, Munn Sann Lye, King-Hwa Lin. Screening of brain-derived neurotrophic factor (BDNF) single nucleotide polymorphisms and plasma BDNF levels among Malaysian major depressive disorder patients. PloS one. vol 14. issue 1. 2019-11-07. PMID:30677092. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin found in abundance in brain regions such as the hippocampus, cortex, cerebellum and basal forebrain. |
2019-11-07 |
2023-08-13 |
Not clear |
| Amal Ahmed Abd El-Fattah, Atef Tadros Fahim, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress. Brain research. vol 1701. 2019-11-04. PMID:30244113. |
cums exposure significantly decreased bdnf and β-catenin expression levels as well as increased gsk-3β expression level in hippocampus. |
2019-11-04 |
2023-08-13 |
rat |
| Amal Ahmed Abd El-Fattah, Atef Tadros Fahim, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress. Brain research. vol 1701. 2019-11-04. PMID:30244113. |
in conclusion, our study revealed that resveratrol and dmf exerted promising antidepressant-like effects in cums rats that are mediated in part by suppressing the neuroinflammation, oxidative stress, apoptosis and up-regulating hippocampal bdnf and β-catenin levels. |
2019-11-04 |
2023-08-13 |
rat |
| Minh Bao Huynh, Mohand Ouidir Ouidja, Sandrine Chantepie, Gilles Carpentier, Auriane Maïza, Ganlin Zhang, Joao Vilares, Rita Raisman-Vozari, Dulce Papy-Garci. Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau. PloS one. vol 14. issue 1. 2019-11-04. PMID:30608949. |
here, we show that total sulfated gags from hippocampus of alzheimer's disease have altered capacities to bind and potentiate the activities of growth factors including fgf-2, vegf, and bdnf while their capacity to bind to tau is remarkable increased. |
2019-11-04 |
2023-08-13 |
Not clear |
| André Spychala, Ulrich Rüthe. FTO affects hippocampal function by regulation of BDNF processing. PloS one. vol 14. issue 2. 2019-11-04. PMID:30730976. |
fto affects hippocampal function by regulation of bdnf processing. |
2019-11-04 |
2023-08-13 |
mouse |
| Deepti Sharma, Kalpana Kumari Barhwal, Surya Narayan Biswal, Anup Kumar Srivastava, Pushpendar Bhardwaj, Ashish Kumar, Om Prakash Chaurasia, Sunil Kumar Hot. Hypoxia-mediated alteration in cholesterol oxidation and raft dynamics regulates BDNF signalling and neurodegeneration in hippocampus. Journal of neurochemistry. vol 148. issue 2. 2019-10-28. PMID:30308090. |
hypoxia-mediated alteration in cholesterol oxidation and raft dynamics regulates bdnf signalling and neurodegeneration in hippocampus. |
2019-10-28 |
2023-08-13 |
rat |
| Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ry. An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:29643431. |
in addition to this decrease in depression-like behavior, brain-derived neurotrophic factor (bdnf) and neuropeptide y (npy) release increased in the hippocampus in response to mai treatment, but estradiol levels did not recover. |
2019-10-25 |
2023-08-13 |
rat |
| Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ry. An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:29643431. |
furthermore, microinjection of the bdnf receptor antagonist ana-12 (0.1 pmol/1 μl) into the hippocampus before mai stimulation significantly suppressed the recovery of npy levels. |
2019-10-25 |
2023-08-13 |
rat |
| Vishnu N Thakare, Rajesh R Patil, Rajesh J Oswal, Valmik D Dhakane, Manoj K Aswar, Bhoomika M Pate. Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice. Journal of psychopharmacology (Oxford, England). vol 32. issue 2. 2019-10-24. PMID:29215318. |
in addition, neurobiochemical alterations, mainly monoamines, 5-ht, ne, da, neurotrophic factor bdnf, and cytokines, il-6, tnf-α, oxidant-antioxidant parameters by determining the malondialdehyde formation (an index of lipid peroxidation process), superoxide dismutase (sod) and catalase (cat) activity in hippocampus and cerebral cortex along with serum corticosterone were investigated. |
2019-10-24 |
2023-08-13 |
mouse |
| Vishnu N Thakare, Rajesh R Patil, Rajesh J Oswal, Valmik D Dhakane, Manoj K Aswar, Bhoomika M Pate. Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice. Journal of psychopharmacology (Oxford, England). vol 32. issue 2. 2019-10-24. PMID:29215318. |
our findings reveal that mice subjected to cums exhibited lower sucrose preference, increase immobility time without affecting general locomotion of the animals, and reduce bdnf, 5-ht, ne, and da level, increased serum corticosterone, il-6 and tnf-α along with an oxidant-antioxidant imbalance in the hippocampus and cerebral cortex. |
2019-10-24 |
2023-08-13 |
mouse |
| Vishnu N Thakare, Rajesh R Patil, Rajesh J Oswal, Valmik D Dhakane, Manoj K Aswar, Bhoomika M Pate. Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice. Journal of psychopharmacology (Oxford, England). vol 32. issue 2. 2019-10-24. PMID:29215318. |
thus, the possible mechanism involved in the antidepressant-like activity of silymarin is correlated to the alleviation of monoaminergic, neurogenesis (enhancing 5-ht, ne, and bdnf levels), and attenuation of inflammatory cytokines system and oxidative stress by modulation of corticosterone response, restoration of antioxidant defense system in cerebral cortex and hippocampus. |
2019-10-24 |
2023-08-13 |
mouse |
| Simo S Zulu, Nicola Simola, Musa V Mabandla, William M U Daniel. Effect of long-term administration of antiretroviral drugs (Tenofovir and Nevirapine) on neuroinflammation and neuroplasticity in mouse hippocampi. Journal of chemical neuroanatomy. vol 94. 2019-10-23. PMID:30336207. |
after treatment, hippocampal tissue was collected from the brains of drug-treated and control mice and the levels of interleukin-1β (il-1β), tumor necrosis factor-α (tnf-α) and brain-derived neurotrophic factor (bdnf) determined. |
2019-10-23 |
2023-08-13 |
mouse |
| Natalia Górska, Jakub Słupski, Łukasz P Szałach, Adam Włodarczyk, Joanna Szarmach, Katarzyna Jakuszkowiak-Wojten, Maria Gałuszko-Węgielnik, Alina Wilkowska, Mariusz Stanisław Wiglusz, Wiesław Jerzy Cubał. Magnesium and ketamine in the treatment of depression. Psychiatria Danubina. vol 31. issue Suppl 3. 2019-10-23. PMID:31488789. |
magnesium and ketamine have a common mechanism of action in the treatment of depression: an increase in glun2b (nmdar subunit) expression is related to the administration of both of the agents, as well as inhibition of phosphorylation of eef2 (eukaryotic elongation factor 2) in cell culture and increase of the expression of bdnf in the hippocampus. |
2019-10-23 |
2023-08-13 |
Not clear |
| Ali-Akbar Salari, Hanieh Samadi, Judith R Homberg, Morteza Kosari-Nasa. Small litter size impairs spatial memory and increases anxiety- like behavior in a strain-dependent manner in male mice. Scientific reports. vol 8. issue 1. 2019-10-22. PMID:30050150. |
we measured body weight, learning and memory, anxiety-related behaviors, interleukin-(il)-1β and brain-derived-neurotrophic-factor (bdnf) levels in the hippocampus, and both basal and stress corticosterone levels in adult mice which have been nursed in small litters compared with those from control litters. |
2019-10-22 |
2023-08-13 |
mouse |
| Ali-Akbar Salari, Hanieh Samadi, Judith R Homberg, Morteza Kosari-Nasa. Small litter size impairs spatial memory and increases anxiety- like behavior in a strain-dependent manner in male mice. Scientific reports. vol 8. issue 1. 2019-10-22. PMID:30050150. |
small litter size significantly decreased spatial memory and hippocampal bdnf levels, and increased hippocampal il-1β, in nmri mice, but not c57bl/6 mice. |
2019-10-22 |
2023-08-13 |
mouse |