| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mauricio P Cunha, Francis L Pazini, Vicente Lieberknecht, Ana Lúcia S Rodrigue. Subchronic administration of creatine produces antidepressant-like effect by modulating hippocampal signaling pathway mediated by FNDC5/BDNF/Akt in mice. Journal of psychiatric research. vol 104. 2019-09-19. PMID:30005372. |
creatine treatment increased pgc-1α, fndc5 and bdnf mrna in the hippocampus as well as bdnf immunocontent. |
2019-09-19 |
2023-08-13 |
mouse |
| Patricia Sampedro-Piquero, Román D Moreno-Fernández, M Carmen Mañas-Padilla, Sara Gil-Rodríguez, Ana Luisa Gavito, Francisco J Pavón, Carmen Pedraza, María García-Fernández, David Ladrón de Guevara-Miranda, Luis J Santín, Estela Castilla-Orteg. Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis. Neurobiology of learning and memory. vol 151. 2019-09-18. PMID:29608953. |
hence we studied how spatial learning to find food rewards in a hole-board maze modulates ahn (cell proliferation and immature neurons) and ahn-related hippocampal neuroplasticity markers (bdnf, igf-ii and creb phosphorylation) in mice. |
2019-09-18 |
2023-08-13 |
mouse |
| Manar A Nader, Hayam Ateyya, Mohamed El-Shafey, Nagla A El-Sherbeen. Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy pathways. Neurochemistry international. vol 115. 2019-09-17. PMID:29032011. |
neuronal damage was also assessed by performing tissue staining by hematoxylin and eosin, estimating hippocampus level of glutamate, gamma-aminobutyric acid (gaba), glial fibrillary acidic protein (gfap) and brain-derived neurotrophic factor (bdnf). |
2019-09-17 |
2023-08-13 |
mouse |
| Iardja Stéfane Lopes, Iris Cristina Maia Oliveira, Victor Celso Cavalcanti Capibaribe, José Tiago Valentim, Daniel Moreira Alves da Silva, Alana Gomes de Souza, Mariana Albuquerque de Araújo, Raquell de Castro Chaves, Stanley Juan Chaves Gutierrez, José Maria Barbosa Filho, Danielle Silveira Macêdo, Francisca Cléa Florenço de Sous. Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms. Neurochemistry international. vol 120. 2019-09-17. PMID:30041016. |
after behavioral evaluation, brain areas (prefrontal cortex, hippocampus and striatum) were dissected for neurochemical evaluation: oxidative stress parameters (mda, nitrite and gsh) and bdnf dosage. |
2019-09-17 |
2023-08-13 |
mouse |
| Iardja Stéfane Lopes, Iris Cristina Maia Oliveira, Victor Celso Cavalcanti Capibaribe, José Tiago Valentim, Daniel Moreira Alves da Silva, Alana Gomes de Souza, Mariana Albuquerque de Araújo, Raquell de Castro Chaves, Stanley Juan Chaves Gutierrez, José Maria Barbosa Filho, Danielle Silveira Macêdo, Francisca Cléa Florenço de Sous. Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms. Neurochemistry international. vol 120. 2019-09-17. PMID:30041016. |
in addition, cort decreased bdnf levels in the mice hippocampus and induced oxidative load in the brain with significative increase in pro-oxidant markers (lipid peroxidation and nitrite levels) and a decline in anti-oxidant defense system (reduced glutathione levels), indicating a direct effect of stress hormones in the induction of the brain oxidative stress. |
2019-09-17 |
2023-08-13 |
mouse |
| Wen Xu, Jian Cao, Yan Zhou, Lina Wang, Guoqi Zh. GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal CA3 of middle-aged mice. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29421611. |
the regulation of hippocampal synaptic plasticity by g1 treatment might be related to brain-derived neurotrophic factor (bdnf)-tropomyosin receptor kinase b (trkb) signaling, as g15 also blocked g1-induced activation of the bdnf-trkb pathway. |
2019-09-16 |
2023-08-13 |
mouse |
| Pâmella K Frühauf-Perez, Fernanda R Temp, Micheli M Pillat, Cristiane Signor, Arithane Lorena Wendel, Henning Ulrich, Carlos F Mello, Maribel A Rubi. Spermine protects from LPS-induced memory deficit via BDNF and TrkB activation. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29458098. |
spermine reversed the decrease of mature bdnf levels induced by lps in both hippocampus and cerebral cortex. |
2019-09-16 |
2023-08-13 |
mouse |
| Pâmella K Frühauf-Perez, Fernanda R Temp, Micheli M Pillat, Cristiane Signor, Arithane Lorena Wendel, Henning Ulrich, Carlos F Mello, Maribel A Rubi. Spermine protects from LPS-induced memory deficit via BDNF and TrkB activation. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29458098. |
the results support that the protective effect of spermine on lps-induced memory deficits depends on trkb receptor activation and is accompanied by restoration of mature bdnf levels in hippocampus and cerebral cortex, as well as increased creb phosphorylation in the cerebral cortex. |
2019-09-16 |
2023-08-13 |
mouse |
| Songqiang Huang, Wanting Dong, Zhexiao Jiao, Jie Liu, Ke Li, Hui Wang, Dan X. Prenatal Dexamethasone Exposure Induced Alterations in Neurobehavior and Hippocampal Glutamatergic System Balance in Female Rat Offspring. Toxicological sciences : an official journal of the Society of Toxicology. 2019-09-13. PMID:31518422. |
the expression of hippocampal glucocorticoid receptors (gr) and histone deacetylase 2 (hdac2) increased, whereas histone h3 lysine 14 acetylation (h3k14ac) of brain-derived neurotrophic factor (bdnf) exon iv (bdnf iv) and expression of bdnf decreased. |
2019-09-13 |
2023-08-13 |
rat |
| Songqiang Huang, Wanting Dong, Zhexiao Jiao, Jie Liu, Ke Li, Hui Wang, Dan X. Prenatal Dexamethasone Exposure Induced Alterations in Neurobehavior and Hippocampal Glutamatergic System Balance in Female Rat Offspring. Toxicological sciences : an official journal of the Society of Toxicology. 2019-09-13. PMID:31518422. |
in vitro, the administration of 0.5 μm dexamethasone to the h19-7 fetal hippocampal neuron cells directly led to a cascade of changes in the gr/hdac2/bdnf pathway, whereas the gr antagonist ru486 and the hdac2 inhibitor romidepsin (rom) reversed changes caused by dexamethasone to the h3k14ac level of bdnf iv and to the expression of bdnf. |
2019-09-13 |
2023-08-13 |
rat |
| Songqiang Huang, Wanting Dong, Zhexiao Jiao, Jie Liu, Ke Li, Hui Wang, Dan X. Prenatal Dexamethasone Exposure Induced Alterations in Neurobehavior and Hippocampal Glutamatergic System Balance in Female Rat Offspring. Toxicological sciences : an official journal of the Society of Toxicology. 2019-09-13. PMID:31518422. |
it is suggested that pde increases the expression of hdac2 by activating gr, reducing the h3k14ac level of bdnf iv, inducing alterations in neurobehavior and hippocampal glutamatergic system balance. |
2019-09-13 |
2023-08-13 |
rat |
| Sriparna Basu, Dinesh Kumar, Shampa Anupurba, Ashish Verma, Ashok Kuma. Effect of maternal iron deficiency anemia on fetal neural development. Journal of perinatology : official journal of the California Perinatal Association. vol 38. issue 3. 2019-09-12. PMID:29234149. |
the present study was conducted to determine the effect of maternal iron deficiency anemia (ida) on fetal hippocampal morphogenesis and production of brain-derived neurotrophic factor (bdnf). |
2019-09-12 |
2023-08-13 |
Not clear |
| Yusrawati, Gustuti Rina, Lipoeto Nur Indrawati, Rizanda Machmu. Differences in brain-derived neurotrophic factor between neonates born to mothers with normal and low ferritin. Asia Pacific journal of clinical nutrition. vol 27. issue 2. 2019-09-11. PMID:29384327. |
maternal iron deficiency in late pregnancy, labor, and the postpartum period has an indirect impact to decrease neurotrophin concentration in the fetal hippocampus, namely brain-derived neurotrophic factor (bdnf). |
2019-09-11 |
2023-08-13 |
Not clear |
| Philip Gerard Gasquoin. Effects of physical activity on delayed memory measures in randomized controlled trials with nonclinical older, mild cognitive impairment, and dementia participants. Journal of clinical and experimental neuropsychology. vol 40. issue 9. 2019-09-10. PMID:29510648. |
the prevailing model derives from animal research and has physical activity directly affecting brain physiology by increasing brain volume, brain-derived neurotrophic factor (bdnf), and hippocampal neurogenesis with consequent gains in neuropsychological test scores. |
2019-09-10 |
2023-08-13 |
human |
| Chao Dong, Ji-Chun Zhang, Qian Ren, Min Ma, Youge Qu, Kai Zhang, Wei Yao, Tamaki Ishima, Hisashi Mori, Kenji Hashimot. Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress. Neurochemistry international. vol 116. 2019-09-10. PMID:29550603. |
in wt mice, csds decreased brain-derived neurotrophic factor (bdnf) expression and phosphorylation/activation of its receptor trkb in prefrontal cortex (pfc), dentate gyrus (dg), and the ca3 region of the hippocampus, but increased bdnf and phosphorylated trkb in the nucleus accumbens (nac). |
2019-09-10 |
2023-08-13 |
mouse |
| Claudia Cristiano, Claudio Pirozzi, Lorena Coretti, Gina Cavaliere, Adriano Lama, Roberto Russo, Francesca Lembo, Maria Pina Mollica, Rosaria Meli, Antonio Calignano, Giuseppina Mattace Ras. Palmitoylethanolamide counteracts autistic-like behaviours in BTBR T+tf/J mice: Contribution of central and peripheral mechanisms. Brain, behavior, and immunity. vol 74. 2019-09-10. PMID:30193877. |
moreover, pea was able to restore hippocampal bdnf signalling pathway, and improve mitochondrial dysfunction, both pathological aspects, known to be consistently associated with asds. |
2019-09-10 |
2023-08-13 |
mouse |
| Ali Ahmadalipour, Shahrbanoo Ghodrati-Jaldbakhan, Seyed Afshin Samaei, Ali Rashidy-Pou. Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment. Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29175674. |
deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal bdnf and long-term potentiation in juvenile rats: beneficial influences of postnatal treadmill exercise and enriched environment. |
2019-09-09 |
2023-08-13 |
rat |
| Ali Ahmadalipour, Shahrbanoo Ghodrati-Jaldbakhan, Seyed Afshin Samaei, Ali Rashidy-Pou. Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment. Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29175674. |
the present study investigated the effects of postnatal exercise and enriched environment (ee) on alterations in water maze learning and hippocampal long-term potentiation (ltp) and brain derived neurotrophic factor (bdnf) levels induced by exposure to morphine during prenatal period in rats. |
2019-09-09 |
2023-08-13 |
rat |
| Ali Ahmadalipour, Shahrbanoo Ghodrati-Jaldbakhan, Seyed Afshin Samaei, Ali Rashidy-Pou. Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment. Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29175674. |
offspring were subjected to postnatal exercise and ee for 30 days and afterward, spatial learning and hippocampal ltp and bdnf levels were investigated. |
2019-09-09 |
2023-08-13 |
rat |
| Ali Ahmadalipour, Shahrbanoo Ghodrati-Jaldbakhan, Seyed Afshin Samaei, Ali Rashidy-Pou. Deleterious effects of prenatal exposure to morphine on the spatial learning and hippocampal BDNF and long-term potentiation in juvenile rats: Beneficial influences of postnatal treadmill exercise and enriched environment. Neurobiology of learning and memory. vol 147. 2019-09-09. PMID:29175674. |
prenatal morphine exposure also caused a reduction in the hippocampal bdnf levels in the female, but not male rats, and postnatal exercise and ee alleviated this deficit. |
2019-09-09 |
2023-08-13 |
rat |