| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyo-Min Jang, Kyung-Eon Lee, Hae-Ji Lee, Dong-Hyun Ki. Immobilization stress-induced Escherichia coli causes anxiety by inducing NF-κB activation through gut microbiota disturbance. Scientific reports. vol 8. issue 1. 2019-12-13. PMID:30224732. |
these treatments increased blood corticosterone and lps levels and anxiety-like behaviors, decreased bdnf expression, and induced nf-κb activation and microglia/monocyte populations in the hippocampus. |
2019-12-13 |
2023-08-13 |
mouse |
| F Biggio, M C Mostallino, G Talani, V Locci, R Mostallino, G Calandra, E Sanna, G Biggi. Social enrichment reverses the isolation-induced deficits of neuronal plasticity in the hippocampus of male rats. Neuropharmacology. vol 151. 2019-12-10. PMID:30935859. |
social enrichment restored the reduction of bdnf, ngf and arc gene expression in the whole hippocampus of social isolated rats. |
2019-12-10 |
2023-08-13 |
rat |
| Yusuke Nakagawa, Masahiro To, Juri Saruta, Yuko Yamamoto, Toshiharu Yamamoto, Tomoko Shimizu, Yohei Kamata, Masato Matsuo, Keiichi Tsukinok. Effect of social isolation stress on saliva BDNF in rat. Journal of oral science. vol 61. issue 4. 2019-11-29. PMID:31631095. |
the bdnf concentration was lower in the hippocampus, prefrontal cortex, blood, and saliva of the stress group than in those of the controls. |
2019-11-29 |
2023-08-13 |
rat |
| Takuya Ogawa, Hidemasa Okihara, Satoshi Kokai, Yasunori Abe, Uchima Koecklin Karin Harumi, Mio Makiguchi, Chiho Kato, Tadachika Yabushita, Makoto Michikawa, Takashi On. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels. Journal of neuroscience research. vol 96. issue 6. 2019-11-25. PMID:29392750. |
brain-derived neurotrophic factor (bdnf), tyrosine kinase receptor b (trkb), and phospho-p44/p42 mitogen-activated protein kinase (mapk) are known to contribute to hippocampal memory/learning. |
2019-11-25 |
2023-08-13 |
mouse |
| Takuya Ogawa, Hidemasa Okihara, Satoshi Kokai, Yasunori Abe, Uchima Koecklin Karin Harumi, Mio Makiguchi, Chiho Kato, Tadachika Yabushita, Makoto Michikawa, Takashi On. Nasal obstruction during adolescence induces memory/learning impairments associated with BDNF/TrkB signaling pathway hypofunction and high corticosterone levels. Journal of neuroscience research. vol 96. issue 6. 2019-11-25. PMID:29392750. |
additionally, the uno group had higher hippocampal bdnf levels and serum corticosterone levels, lower hippocampal trkb and phospho-p44/p42 mapk levels, and reduced neuron numbers relative to controls. |
2019-11-25 |
2023-08-13 |
mouse |
| Michela Bistoletti, Valentina Caputi, Nicolò Baranzini, Nicoletta Marchesi, Viviana Filpa, Ilaria Marsilio, Silvia Cerantola, Genciana Terova, Andreina Baj, Annalisa Grimaldi, Alessia Pascale, Gianmario Frigo, Francesca Crema, Maria Cecilia Giron, Cristina Giaron. Antibiotic treatment-induced dysbiosis differently affects BDNF and TrkB expression in the brain and in the gut of juvenile mice. PloS one. vol 14. issue 2. 2019-11-21. PMID:30794676. |
bdnf and trkb protein levels were downregulated in the hippocampus and remained unchanged in the prefrontal cortex of abx-treated animals. |
2019-11-21 |
2023-08-13 |
mouse |
| John S. Rudge, Ralph F. Alderson, Elizabeth Pasnikowski, Joyce McClain, Nancy Y. Ip, Ronald M. Lindsa. Expression of Ciliary Neurotrophic Factor and the Neurotrophins-Nerve Growth Factor, Brain-Derived Neurotrophic Factor and Neurotrophin 3-in Cultured Rat Hippocampal Astrocytes. The European journal of neuroscience. vol 4. issue 6. 2019-11-20. PMID:12106332. |
in order to examine which factors may be responsible for these activities, we have examined the expression of the genes for four known neurotrophic factors-ciliary neurotrophic factor (cntf), nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin 3 (nt3)-in purified astrocyte cultures derived from neonatal rat hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
exercise has been found to increase bdnf mrna levels in various brain regions, including specific subpopulations of hippocampal neurons. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
expression of bdnf mrna in the hippocampus was assessed with in situ hybridization and densitometry. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
hybridization signal for bdnf mrna was significantly increased bilaterally in the exercise group in hippocampal regions ca1 and ca3 (p<0.05), but not in the granule cell layer of the dentate gyrus. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
this study suggests that after traumatic brain injury, exercise elevates bdnf mrna in specific regions of the hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Xuan Liu, Junjian Zhang, Dong Sun, Yuanteng Fan, Hongbin Zhou, Binfang F. Fluoxetine enhances Brain Derived Neurotropic Factor Serum Concentration and Cognition in Patients with Vascular Dementia. Current neurovascular research. 2019-11-20. PMID:23962390. |
selective serotonin reuptake inhibitors (ssris) improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (bdnf) in the rat hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Damian G Maur, Cecilia G Pascuan, Ana M Genaro, Maria A Zorrilla-Zubilet. Involvement of Nitric Oxide, Neurotrophins and HPA Axis in Neurobehavioural Alterations Induced by Prenatal Stress. Advances in neurobiology. vol 10. 2019-11-20. PMID:25287536. |
thus, it has been found that the neuronal isoform of nitric oxide synthase (nnos) is an endogenous inhibitor of glucocorticoid receptor (gr) in the hippocampus and that nnos in the hippocampus may participate in the modulation of hypothalamic-pituitary-adrenal axis activity via gr.neurotrophins are a family of secreted growth factors consisting of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt3) and nt4. |
2019-11-20 |
2023-08-13 |
Not clear |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
transplantation to the anterior chamber of the eye increased the expression of bdnf in the hippocampal but not the brain stem tissue, compared with levels observed in fetal and adult rats in vivo. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
in addition, double grafting with hippocampal tissue more than tripled bdnf levels in brain stem grafts and doubled bdnf levels in the hippocampal portion of double grafts compared with hippocampal single grafts. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
triple grafts containing basal forebrain, hippocampus, and brain stem lc tissue increased brain stem and hippocampal bdnf levels even further. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
colchicine treatment of lc-hippocampal double grafts gave rise to a significant decrease in hippocampal bdnf levels to levels seen in single hippocampal grafts, while only a partial reduction of bdnf levels was seen in the brain stem portion of the same double grafts treated with colchicine. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
the findings suggest that an appropriate hippocampal innervation or contact with its target tissues is essential for regulation of bdnf expression in the brain stem, and that retrograde transport of bdnf can occur between double grafted fetal tissues in oculo. |
2019-11-20 |
2023-08-13 |
rat |
| Mu-Huo Ji, Hui Tang, Dan Luo, Li-Li Qiu, Min Jia, Hong-Mei Yuan, Shan-Wu Feng, Jian-Jun Yan. Environmental conditions differentially affect neurobehavioral outcomes in a mouse model of sepsis-associated encephalopathy. Oncotarget. vol 8. issue 47. 2019-11-20. PMID:29137271. |
the expressions of proinflammatory cytokines (tumor necrosis factor (tnf-α), interleukin-1β (il-1β), il-6, il-10), ionized calcium-binding adaptor molecule-1 (iba1)-positive cells as well as glial fibrillary acidic protein (gfap)-positive cells, brain derived neurotrophic factor (bdnf), 5-bromo-2-deoxyuridine-labeled cells in the dentate gyrus of the hippocampus, and the number of dendritic spines in the hippocampal ca1 were determined. |
2019-11-20 |
2023-08-13 |
mouse |
| Shih-Wen Li, Hong-Ren Yu, Jiunn-Ming Sheen, Mao-Meng Tiao, You-Lin Tain, I-Chun Lin, Yu-Ju Lin, Kow-Aung Chang, Ching-Chou Tsai, Li-Tung Huan. A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol. Oncotarget. vol 8. issue 67. 2019-11-20. PMID:29340106. |
dorsal hippocampal expression of certain biochemical molecules, including sirtuin 1, erk, pparγ, adiponectin, and bdnf were measured. |
2019-11-20 |
2023-08-13 |
rat |