| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chandan Sona, Ajeet Kumar, Shalini Dogra, Boda Arun Kumar, Deepmala Umrao, Prem N Yada. Docosahexaenoic acid modulates brain-derived neurotrophic factor via GPR40 in the brain and alleviates diabesity-associated learning and memory deficits in mice. Neurobiology of disease. vol 118. 2019-09-09. PMID:29981843. |
finally, the central nervous system (cns)-specific blockade of gpr40 signaling abrogated the memory potentiating effects of dha, and induction of bdnf expression in the hippocampus. |
2019-09-09 |
2023-08-13 |
mouse |
| Joel E Soler, Margaret Stumpfig, Yu-Ping Tang, Alfred J Robison, Antonio A Núñez, Lily Ya. Daytime Light Intensity Modulates Spatial Learning and Hippocampal Plasticity in Female Nile Grass Rats (Arvicanthis niloticus). Neuroscience. vol 404. 2019-09-05. PMID:30690136. |
our previous work using diurnal male nile grass rats (arvicanthis niloticus) revealed that reduced illuminance during the day leads to impairments in hippocampal-dependent spatial learning/memory, reduced ca1 dendritic spine density, and attenuated hippocampal brain-derived neurotrophic factor (bdnf) expression in males. |
2019-09-05 |
2023-08-13 |
human |
| Joel E Soler, Margaret Stumpfig, Yu-Ping Tang, Alfred J Robison, Antonio A Núñez, Lily Ya. Daytime Light Intensity Modulates Spatial Learning and Hippocampal Plasticity in Female Nile Grass Rats (Arvicanthis niloticus). Neuroscience. vol 404. 2019-09-05. PMID:30690136. |
in contrast to the attenuated hippocampal bdnf expression found in dimld males, there was no significant difference in the expression of bdnf and of its receptor trkb between females in brld and dimld. |
2019-09-05 |
2023-08-13 |
human |
| Yu-Xin Liu, Dong Ya. [Effects of dexmedetomidine on the growth and development of rat hippocampal neurons and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 1. 2019-09-05. PMID:31245956. |
to investigate the effects of dexmedetomidine (dex) on hippocampal neuron development process and the expressions of molecules in brain-derived neurotropic factor (bdnf)-tyrosine receptor kinase b (trkb) signaling pathway in neonatal rats. |
2019-09-05 |
2023-08-13 |
rat |
| Márcio Silveira Corrêa, Daiane Borba de Lima, Bruno Lima Giacobbo, Kelem Vedovelli, Irani Iracema de Lima Argimon, Elke Bromber. Mental health in familial caregivers of Alzheimer's disease patients: are the effects of chronic stress on cognition inevitable? Stress (Amsterdam, Netherlands). vol 22. issue 1. 2019-09-04. PMID:30382760. |
the contextual memory impairment of caregivers was associated with prefrontal and hippocampal cognitive dysfunctions, alterations of the cortisol/dhea ratio and lower bdnf levels. |
2019-09-04 |
2023-08-13 |
human |
| Luisa Azambuja Alcalde, Betânia Souza de Freitas, Gustavo Dalto Barroso Machado, Pedro Castilhos de Freitas Crivelaro, Victoria Campos Dornelles, Henrique Gus, Ricardo Tavares Monteiro, Luiza Wilges Kist, Mauricio Reis Bogo, Nadja Schröde. Iron chelator deferiprone rescues memory deficits, hippocampal BDNF levels and antioxidant defenses in an experimental model of memory impairment. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 31. issue 6. 2019-09-03. PMID:30117045. |
iron chelator deferiprone rescues memory deficits, hippocampal bdnf levels and antioxidant defenses in an experimental model of memory impairment. |
2019-09-03 |
2023-08-13 |
rat |
| Huiling Fu, Li Liu, Yue Tong, Yuanjie Li, Xia Zhang, Xiaojuan Gao, Jingjiao Yong, Jianjun Zhao, Dong Xiao, Kuishen Wen, Hanqing Wan. The antidepressant effects of hesperidin on chronic unpredictable mild stress-induced mice. European journal of pharmacology. vol 853. 2019-09-03. PMID:30928632. |
furthermore, the protein expression levels of high-mobility group box 1 protein (hmgb1), receptor for advanced glycation end-products (rage)/nf-κb and brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase b (trkb) pathway in the hippocampus and corticosterone-induced pc12 cells were detected by western blot. |
2019-09-03 |
2023-08-13 |
mouse |
| Pei Shen, Qiang Yue, Wan Fu, Shao-Wen Tian, Yong Yo. Apelin-13 ameliorates chronic water-immersion restraint stress-induced memory performance deficit through upregulation of BDNF in rats. Neuroscience letters. vol 696. 2019-09-02. PMID:30500396. |
furthermore, apelin-13 ameliorated cwirs-induced hippocampal bdnf expression deficit, and the trkb receptor antagonist ana-12 blocked the ameliorative effect of apelin-13 on memory performance deficit in cwirs rats. |
2019-09-02 |
2023-08-13 |
rat |
| Mi Kyoung Seo, Jung Goo Lee, Sung Woo Par. Effects of escitalopram and ibuprofen on a depression-like phenotype induced by chronic stress in rats. Neuroscience letters. vol 696. 2019-09-02. PMID:30586639. |
immobility time was measured by the forced swimming test (fst), and hippocampal bdnf and p11 levels were analyzed by quantitative real-time polymerase chain reaction and western blotting. |
2019-09-02 |
2023-08-13 |
mouse |
| Mi Kyoung Seo, Jung Goo Lee, Sung Woo Par. Effects of escitalopram and ibuprofen on a depression-like phenotype induced by chronic stress in rats. Neuroscience letters. vol 696. 2019-09-02. PMID:30586639. |
the levels of bdnf and p11 in the hippocampus decreased significantly in response to crs. |
2019-09-02 |
2023-08-13 |
mouse |
| Juliana R Bastos, Katherinne M Perico, Érica L Marciano Vieira, Antônio L Teixeira, Fabiana S Machado, Aline S de Miranda, Fabrício A Moreir. Inhibition of the dopamine transporter as an animal model of bipolar disorder mania: Locomotor response, neuroimmunological profile and pharmacological modulation. Journal of psychiatric research. vol 102. 2019-08-29. PMID:29656188. |
this compound also induced changes in il-2 and bdnf levels in prefrontal cortex; il-2, il-4 and il-10 in striatum; and il-10, il-4, ifn-γ and ngf in hippocampus. |
2019-08-29 |
2023-08-13 |
mouse |
| Manoj P Dandekar, Ashwini Saxena, Giselli Scaini, Joo Hyun Shin, Agata Migut, Vijayasree Vayalanellore Giridharan, Yuzhi Zhou, Tatiana Barichello, Jair C Soares, Joao Quevedo, Albert J Feno. Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30317434. |
interestingly, decreased levels of bdnf in the cus animals were augmented in the plasma, csf, and hippocampus following mfb-dbs, but remained unaltered in the nucleus accumbens (nac). |
2019-08-29 |
2023-08-13 |
rat |
| Alessandra Mallei, Alessandro Ieraci, Stefano Corna, Daniela Tardito, Francis S Lee, Maurizio Popol. Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30067287. |
global epigenetic analysis of bdnf val66met mice hippocampus reveals changes in dendrite and spine remodeling genes. |
2019-08-26 |
2023-08-13 |
mouse |
| Alessandra Mallei, Alessandro Ieraci, Stefano Corna, Daniela Tardito, Francis S Lee, Maurizio Popol. Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30067287. |
brain-derived neurotrophic factor (bdnf), a neurotrophin highly expressed in the hippocampus, plays crucial roles in cognition, neuroplasticity, synaptic function, and dendritic remodeling. |
2019-08-26 |
2023-08-13 |
mouse |
| Alessandra Mallei, Alessandro Ieraci, Stefano Corna, Daniela Tardito, Francis S Lee, Maurizio Popol. Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30067287. |
the aim of this study was to investigate the impact of the bdnf val66met polymorphism in the knock-in mouse model on two hippocampal epigenetic marks for transcriptional repression and activation, respectively: trimethylation of lysine 27 on histone h3 (h3k27me3) and acetylation of histone h3 (ach3), using a genome-wide approach. |
2019-08-26 |
2023-08-13 |
mouse |
| Laiali Alquraan, Karem H Alzoubi, Hana Hammad, Suzie Y Rababa'h, Fadia Mayya. Omega-3 Fatty Acids Prevent Post-Traumatic Stress Disorder-Induced Memory Impairment. Biomolecules. vol 9. issue 3. 2019-08-22. PMID:30871113. |
changes in oxidative stress biomarkers, thiobarbituric acid reactive substances (tbars), and brain derived neuroptrophic factor (bdnf) in the hippocampus following treatments were measured. |
2019-08-22 |
2023-08-13 |
rat |
| Fernando Dobrachinski, Rogério R Gerbatin, Gláubia Sartori, Ronaldo M Golombieski, Alfredo Antoniazzi, Cristina W Nogueira, Luiz F Royes, Michele R Fighera, Lisiane O Porciúncula, Rodrigo A Cunha, Félix A A Soare. Guanosine Attenuates Behavioral Deficits After Traumatic Brain Injury by Modulation of Adenosinergic Receptors. Molecular neurobiology. vol 56. issue 5. 2019-08-20. PMID:30105669. |
this was accompanied by a decreased expression of both synaptic (synaptophysin) and plasticity proteins (bdnf and creb), a loss of cresyl violet-stained neurons, and increased astrogliosis and microgliosis in the hippocampus. |
2019-08-20 |
2023-08-13 |
human |
| YiLong Dong, KangJing Pu, WenJing Duan, HuiCheng Chen, LiXing Chen, YanMei Wan. Involvement of Akt/CREB signaling pathways in the protective effect of EPA against interleukin-1β-induced cytotoxicity and BDNF down-regulation in cultured rat hippocampal neurons. BMC neuroscience. vol 19. issue 1. 2019-08-19. PMID:30189852. |
involvement of akt/creb signaling pathways in the protective effect of epa against interleukin-1β-induced cytotoxicity and bdnf down-regulation in cultured rat hippocampal neurons. |
2019-08-19 |
2023-08-13 |
rat |
| Bo-Yu Shi, Zhi-Li Rao, Jie Luo, Xiao-Bo Liu, Yang Fang, Hai-Juan Cao, Nan Zen. [Protective effect and mechanism of Xiaoyao San on lipopolysaccharide-induced hippocampal neurons injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 4. 2019-08-14. PMID:30989892. |
the effect of xiaoyao san serum( final concentration of4%,8%) on the cell proliferation activity was detected by immunofluorescence,the levels of bdnf and β-ngf in the supernatant of hippocampal neurons were detected by elisa,and the expressions of bdnf,ngf,trk b,trk a and creb mrna in cell lysate of hippocampal neuron were detected by pcr. |
2019-08-14 |
2023-08-13 |
Not clear |
| Huancun Feng, Canmao Wang, Wei He, Xinjun Wu, Shujie Li, Zhenkun Zeng, Meidan Wei, Binghong H. Roflumilast ameliorates cognitive impairment in APP/PS1 mice via cAMP/CREB/BDNF signaling and anti-neuroinflammatory effects. Metabolic brain disease. vol 34. issue 2. 2019-08-13. PMID:30610438. |
in addition, roflumilast increased the camp, phosphorylated camp response-element binding protein (p-creb) and brain-derived neurotrophic factor (bdnf) levels, and reduced the nuclear translocation of nuclear factor-kappa b (nf-κb) p65, and proinflammatory cytokine (il-6, tnf-a and il-1β) levels in the hippocampus of app/ps1 transgenic mice. |
2019-08-13 |
2023-08-13 |
mouse |