| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rosy Wang, R M Damian Holsinge. Exercise-induced brain-derived neurotrophic factor expression: Therapeutic implications for Alzheimer's dementia. Ageing research reviews. vol 48. 2019-07-29. PMID:30326283. |
this perspective draws upon evidence from animal and human studies to highlight such a mechanism whereby exercise drives synthesis and accumulation of neuroactive metabolites such as myokines and ketone bodies in the periphery and in the hippocampus to enhance bdnf expression. |
2019-07-29 |
2023-08-13 |
human |
| Rosy Wang, R M Damian Holsinge. Exercise-induced brain-derived neurotrophic factor expression: Therapeutic implications for Alzheimer's dementia. Ageing research reviews. vol 48. 2019-07-29. PMID:30326283. |
similarly, both bdnf and cardiovascular fitness arising from aerobic exercise have been positively associated with hippocampal volume and function in humans. |
2019-07-29 |
2023-08-13 |
human |
| Xing Wang, Jie Chen, Hailou Zhang, Zhiheng Huang, Zhilu Zou, Yin Chen, Lei Sheng, Wenda Xue, Juanjuan Tang, Haoxin Wu, Hongquan Liu, Gang Che. Immediate and persistent antidepressant-like effects of Chaihu-jia-Longgu-Muli-tang are associated with instantly up-regulated BDNF in the hippocampus of mice. Bioscience reports. vol 39. issue 1. 2019-07-29. PMID:30473537. |
immediate and persistent antidepressant-like effects of chaihu-jia-longgu-muli-tang are associated with instantly up-regulated bdnf in the hippocampus of mice. |
2019-07-29 |
2023-08-13 |
mouse |
| Xing Wang, Jie Chen, Hailou Zhang, Zhiheng Huang, Zhilu Zou, Yin Chen, Lei Sheng, Wenda Xue, Juanjuan Tang, Haoxin Wu, Hongquan Liu, Gang Che. Immediate and persistent antidepressant-like effects of Chaihu-jia-Longgu-Muli-tang are associated with instantly up-regulated BDNF in the hippocampus of mice. Bioscience reports. vol 39. issue 1. 2019-07-29. PMID:30473537. |
here, we aimed to evaluate the immediate and persistent antidepressant-like action of a classic herbal medicine chaihu-jia-longgu-muli decoction (clm) as well as the action of clm on hippocampal brain-derived neurotrophic factor (bdnf) over time. |
2019-07-29 |
2023-08-13 |
mouse |
| Xing Wang, Jie Chen, Hailou Zhang, Zhiheng Huang, Zhilu Zou, Yin Chen, Lei Sheng, Wenda Xue, Juanjuan Tang, Haoxin Wu, Hongquan Liu, Gang Che. Immediate and persistent antidepressant-like effects of Chaihu-jia-Longgu-Muli-tang are associated with instantly up-regulated BDNF in the hippocampus of mice. Bioscience reports. vol 39. issue 1. 2019-07-29. PMID:30473537. |
bdnf expression in the hippocampus was examined at 30 min and 24 hr post a single clm. |
2019-07-29 |
2023-08-13 |
mouse |
| Xing Wang, Jie Chen, Hailou Zhang, Zhiheng Huang, Zhilu Zou, Yin Chen, Lei Sheng, Wenda Xue, Juanjuan Tang, Haoxin Wu, Hongquan Liu, Gang Che. Immediate and persistent antidepressant-like effects of Chaihu-jia-Longgu-Muli-tang are associated with instantly up-regulated BDNF in the hippocampus of mice. Bioscience reports. vol 39. issue 1. 2019-07-29. PMID:30473537. |
the results support that chaihu-jia-longgu-muli decoction was capable to immediately and enduringly elicit antidepressant activity via enhancement of hippocampal bdnf expression, in which the constituent xiaochaihu decoction played the primary role. |
2019-07-29 |
2023-08-13 |
mouse |
| Emily D K Sullivan, Molly Kent, Brooke Thompson, Massi Bardi, Kelly Lamber. Maternal-induced shifts in allostatic demands: Reproductive experience alters emotional and cognitive biobehavioral responses in rats (Rattus norvegicus). Neuroscience letters. vol 701. 2019-07-29. PMID:30708127. |
finally, prim animals had less hippocampal glucocorticoid receptor immunoreactivity and more hippocampal bdnf immunoreactivity than null animals. |
2019-07-29 |
2023-08-13 |
rat |
| Yanxia Lu, Cyrus S Ho, Roger S McIntyre, Wei Wang, Roger C H. Effects of vortioxetine and fluoxetine on the level of Brain Derived Neurotrophic Factors (BDNF) in the hippocampus of chronic unpredictable mild stress-induced depressive rats. Brain research bulletin. vol 142. 2019-07-26. PMID:29933036. |
effects of vortioxetine and fluoxetine on the level of brain derived neurotrophic factors (bdnf) in the hippocampus of chronic unpredictable mild stress-induced depressive rats. |
2019-07-26 |
2023-08-13 |
human |
| Yanxia Lu, Cyrus S Ho, Roger S McIntyre, Wei Wang, Roger C H. Effects of vortioxetine and fluoxetine on the level of Brain Derived Neurotrophic Factors (BDNF) in the hippocampus of chronic unpredictable mild stress-induced depressive rats. Brain research bulletin. vol 142. 2019-07-26. PMID:29933036. |
the mean optical density value of hippocampal bdnf was significantly higher in the cums + vor group than the cums and cums + flu groups. |
2019-07-26 |
2023-08-13 |
human |
| Yanxia Lu, Cyrus S Ho, Roger S McIntyre, Wei Wang, Roger C H. Effects of vortioxetine and fluoxetine on the level of Brain Derived Neurotrophic Factors (BDNF) in the hippocampus of chronic unpredictable mild stress-induced depressive rats. Brain research bulletin. vol 142. 2019-07-26. PMID:29933036. |
in conclusion, vortioxetine, but not fluoxetine, increased hippocampal bdnf levels in rats subject to cums. |
2019-07-26 |
2023-08-13 |
human |
| D Mercerón-Martínez, W Almaguer-Melian, E Alberti-Amador, J A Bergad. Amygdala stimulation promotes recovery of behavioral performance in a spatial memory task and increases GAP-43 and MAP-2 in the hippocampus and prefrontal cortex of male rats. Brain research bulletin. vol 142. 2019-07-26. PMID:29933038. |
bla electrical stimulation rises bdnf rna expression, bdnf protein levels, and arc rna expression in the hippocampus. |
2019-07-26 |
2023-08-13 |
rat |
| Peng Huang, Tingting Gao, Zhaoyang Dong, Chuying Zhou, Yuling Lai, Ting Pan, Yuan Liu, Xiaoshan Zhao, Xuegang Sun, Heyu Hua, Ge Wen, Lei Gao, Zhiping L. Neural circuitry among connecting the hippocampus, prefrontal cortex and basolateral amygdala in a mouse depression model: Associations correlations between BDNF levels and BOLD - fMRI signals. Brain research bulletin. vol 142. 2019-07-26. PMID:29969645. |
neural circuitry among connecting the hippocampus, prefrontal cortex and basolateral amygdala in a mouse depression model: associations correlations between bdnf levels and bold - fmri signals. |
2019-07-26 |
2023-08-13 |
mouse |
| Jing Gao, Kai Li, Lingfang Du, Hongqiang Yin, Xiaoyue Tan, Zhuo Yan. Deletion of asparagine endopeptidase reduces anxiety- and depressive-like behaviors and improves abilities of spatial cognition in mice. Brain research bulletin. vol 142. 2019-07-26. PMID:30030107. |
otherwise, the level of bdnf protein was reduced and the level of nf-κb p65 protein was increased in hippocampus and frontal cortex of aep ko mice. |
2019-07-26 |
2023-08-13 |
mouse |
| Zheng Xu, Can Wang, Xiaoguang Dong, Tao Hu, Lingling Wang, Wenbo Zhao, Shaowei Zhu, Guibao Li, Yanlai Hu, Qing Gao, Jiale Wan, Zengxun Liu, Jinhao Su. Chronic alcohol exposure induced gut microbiota dysbiosis and its correlations with neuropsychic behaviors and brain BDNF/Gabra1 changes in mice. BioFactors (Oxford, England). vol 45. issue 2. 2019-07-22. PMID:30417952. |
were also correlated with pfc bdnf and hippocampus gabra1 level. |
2019-07-22 |
2023-08-13 |
mouse |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
compared to young mice, bdnf messenger rna (mrna) and protein levels and those core neuroplasticity factors (neurotransmitter γ-aminobutyric acid [gaba] level, gabaa-r α2 and α5 subunits expression and gaba+ neurons) in hippocampus markedly decreased with anxiety-like behavior in aged mice. |
2019-07-22 |
2023-08-13 |
mouse |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
we demonstrated that the basic function of bdnf in hippocampus was negatively correlated with gnd and anxiety-like behavior of aged mice. |
2019-07-22 |
2023-08-13 |
mouse |
| Gongbei Zhu, Xiaofei Sun, Yun Yang, Yao Du, Yuhan Lin, Jianming Xiang, Ningna Zho. Reduction of BDNF results in GABAergic neuroplasticity dysfunction and contributes to late-life anxiety disorder. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714802. |
these results provided evidence of a causal relationship between the reduced bdnf function in hippocampus and the anxiety susceptibility of aged mice. |
2019-07-22 |
2023-08-13 |
mouse |
| Sen Wang, Xu-Feng Huang, Peng Zhang, Kelly A Newell, Hongqin Wang, Kuiyang Zheng, Yinghua Y. Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese mice. Scientific reports. vol 7. issue 1. 2019-07-16. PMID:28939875. |
teasaponin treatment prevented the hf diet-induced recognition memory impairment and improved neuroinflammation, gliosis and brain-derived neurotrophic factor (bdnf) deficits in the hippocampus. |
2019-07-16 |
2023-08-13 |
mouse |
| Hui-Juan Jin, Lei Pei, Ya-Nan Li, Hui Zheng, Shuai Yang, Yan Wan, Ling Mao, Yuan-Peng Xia, Quan-Wei He, Man Li, Zhen-Yu Yue, Bo H. Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. Scientific reports. vol 7. issue 1. 2019-07-15. PMID:29097744. |
in the process, we confirmed that fluoxetine could improve the depression-like behaviors of psd mice and upregulate the expression of bdnf in the hippocampus. |
2019-07-15 |
2023-08-13 |
mouse |
| Hui-Juan Jin, Lei Pei, Ya-Nan Li, Hui Zheng, Shuai Yang, Yan Wan, Ling Mao, Yuan-Peng Xia, Quan-Wei He, Man Li, Zhen-Yu Yue, Bo H. Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. Scientific reports. vol 7. issue 1. 2019-07-15. PMID:29097744. |
however, depletion of bdnf by transfecting lentivirus-derived shbdnf in hippocampus suppressed the effect of fluoxetine. |
2019-07-15 |
2023-08-13 |
mouse |