| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martina Parrini, Diego Ghezzi, Gabriele Deidda, Lucian Medrihan, Enrico Castroflorio, Micol Alberti, Pietro Baldelli, Laura Cancedda, Andrea Contestabil. Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome. Scientific reports. vol 7. issue 1. 2019-07-05. PMID:29203796. |
additionally, the expression of brain-derived neurotrophic factor (bdnf) was markedly decreased in the hippocampus of patients with ds. |
2019-07-05 |
2023-08-13 |
mouse |
| Katarina Buzgoova, Jan Graban, Lucia Balagova, Natasa Hlavacova, Daniela Jezov. Brain derived neurotrophic factor expression and DNA methylation in response to subchronic valproic acid and/or aldosterone treatment. Croatian medical journal. vol 60. issue 2. 2019-07-05. PMID:31044578. |
to test the hypothesis that valproic acid treatment positively affects brain-derived neurotrophic factor (bdnf) expression and dna methylation in the hippocampus and brain cortex of rats simultaneously treated with aldosterone. |
2019-07-05 |
2023-08-13 |
rat |
| Li Wang, Yilixiati Xiaokaiti, Gang Wang, Xiaoxiao Xu, Ling Chen, Xianfeng Huang, Li Liu, Jianchun Pan, Shuqun Hu, Zhuoyou Chen, Ying X. Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways. Scientific reports. vol 7. issue 1. 2019-06-27. PMID:28935920. |
il-22 and il-17, bax and bcl-2, pka/pkg and the brain derived neurotropic factor (bdnf) levels in hippocampus and cortex were detected with immunoblotting assay. |
2019-06-27 |
2023-08-13 |
Not clear |
| Katja Burk, Binu Ramachandran, Saheeb Ahmed, Joaquin I Hurtado-Zavala, Ankit Awasthi, Eva Benito, Ruth Faram, Hamid Ahmad, Aarti Swaminathan, Jeffrey McIlhinney, Andre Fischer, Pavel Perestenko, Camin Dea. Regulation of Dendritic Spine Morphology in Hippocampal Neurons by Copine-6. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 4. 2019-06-26. PMID:28158493. |
we found that brain-derived neurotrophic factor (bdnf) - a molecule essential for long-term potentiation of synaptic strength - upregulated and recruited copine-6 to dendritic spines in hippocampal neurons. |
2019-06-26 |
2023-08-13 |
Not clear |
| Xing-Ming Wang, Wei Pan, Ning Xu, Zhi-Qiang Zhou, Guang-Fen Zhang, Jin-Chun She. Environmental enrichment improves long-term memory impairment and aberrant synaptic plasticity by BDNF/TrkB signaling in nerve-injured mice. Neuroscience letters. vol 694. 2019-06-21. PMID:30496785. |
the pain threshold, long-term memory, expression of brain-derived neurotrophic factor (bdnf) and synaptic plasticity in hippocampus were determined. |
2019-06-21 |
2023-08-13 |
mouse |
| Xing-Ming Wang, Wei Pan, Ning Xu, Zhi-Qiang Zhou, Guang-Fen Zhang, Jin-Chun She. Environmental enrichment improves long-term memory impairment and aberrant synaptic plasticity by BDNF/TrkB signaling in nerve-injured mice. Neuroscience letters. vol 694. 2019-06-21. PMID:30496785. |
cci also induced the reduction of bdnf expression and synaptic plasticity impairments in the hippocampus, as represented by the dendritic spine density and postsynaptic density protein (psd)-95 reduction, and long-term potential (ltp) dysfunction. |
2019-06-21 |
2023-08-13 |
mouse |
| C Jiang, W-J Lin, M Sadahiro, B Labonté, C Menard, M L Pfau, C A Tamminga, G Turecki, E J Nestler, S J Russo, S R Salto. VGF function in depression and antidepressant efficacy. Molecular psychiatry. vol 23. issue 7. 2019-06-17. PMID:29158577. |
in hippocampus, the antidepressant response to ketamine is associated with rapid vgf translation, is impaired by reduced vgf expression, and as previously reported, requires coincident, rapid bdnf translation and release. |
2019-06-17 |
2023-08-13 |
mouse |
| Xiaoli Wu, Benqin Tang, Xian Liao, Ziren Su, Simon Ming-Yuen Lee, Yefeng Cai, Chuwen L. Suppressive effects of the supercritical-carbon dioxide fluid extract of Chrysanthemum indicum on chronic unpredictable mild stress-induced depressive-like behavior in mice. Food & function. vol 10. issue 2. 2019-06-14. PMID:30741293. |
interestingly, further investigations demonstrated that sec inhibited cums-induced activation of the nuclear factor kappa b (nf-κb) and nod-like receptor protein 3 (nlrp3) inflammasomes pathways but upregulated brain-derived neurotrophic factor (bdnf) expression and promoted phosphorylation of extracellular signal-regulated kinase (erk) and camp-response element-binding protein (creb) in hippocampal. |
2019-06-14 |
2023-08-13 |
mouse |
| b' Jelena Petrovi\\xc4\\x87, Du\\xc5\\xa1anka Stani\\xc4\\x87, Zorica Bulat, Nela Pu\\xc5\\xa1ka\\xc5\\xa1, Milica Labudovi\\xc4\\x87-Borovi\\xc4\\x87, Bojan Batini\\xc4\\x87, Du\\xc5\\xa1ko Mirkovi\\xc4\\x87, Svetlana Ignjatovi\\xc4\\x87, Vesna Pe\\xc5\\xa1i\\xc4\\x8. Acth-induced model of depression resistant to tricyclic antidepressants: Neuroendocrine and behavioral changes and influence of long-term magnesium administration. Hormones and behavior. vol 105. 2019-06-12. PMID:30025718.' |
our results support beneficial behavioral impact of mg in trd model together with increased hippocampal neurogenesis and bdnf expression. |
2019-06-12 |
2023-08-13 |
rat |
| Su-Su Tang, Yi Ren, Li-Jie Xu, Jing-Ran Cao, Hao Hong, Hui Ji, Qing-Hua H. Activation of ERα and/or ERβ ameliorates cognitive impairment and apoptosis in streptozotocin-induced diabetic mice. Hormones and behavior. vol 105. 2019-06-12. PMID:30096284. |
importantly, treatment with the pharmacologic ers agonists caused significant increases in the membrane erα and erβ expression and subsequent pi3k/akt, creb and bdnf activation in the hippocampus of diabetic mice. |
2019-06-12 |
2023-08-13 |
mouse |
| Hong Liu, Jie Yang, Kai Wang, Tengfei Niu, Dongya Huan. Moderate- and Low-Dose of Atorvastatin Alleviate Cognition Impairment Induced by High-Fat Diet via Sirt1 Activation. Neurochemical research. vol 44. issue 5. 2019-06-11. PMID:30820818. |
the level of cognition development was examined by morris water maze (mwm) approach and novel object recognition test (nort); besides, the expression of creb1, gap-43, bdnf, camkii, and erks of frontal cortex and hippocampus was determined by reverse transcription polymerase chain reaction (rt-pcr). |
2019-06-11 |
2023-08-13 |
mouse |
| Abhik Sen, Thomas J Nelson, Daniel L Alkon, Jarin Hongpaisa. Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's disease : JAD. vol 63. issue 3. 2019-06-10. PMID:29710707. |
loss in pkc epsilon causes downregulation of mnsod and bdnf expression in neurons of alzheimer's disease hippocampus. |
2019-06-10 |
2023-08-13 |
mouse |
| Abhik Sen, Thomas J Nelson, Daniel L Alkon, Jarin Hongpaisa. Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's disease : JAD. vol 63. issue 3. 2019-06-10. PMID:29710707. |
reduced levels of pkcɛ, mnsod, and bdnf and an increased level of aβ were also found in hippocampal neurons from autopsy-confirmed ad patients. |
2019-06-10 |
2023-08-13 |
mouse |
| Ji-Xiao Zhu, Jia-Ling Shan, Wei-Qiong Hu, Jin-Xiang Zeng, Ji-Cheng Sh. Gallic acid activates hippocampal BDNF-Akt-mTOR signaling in chronic mild stress. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30280285. |
in addition, gallic acid promoted both the bdnf and p-trkb levels in the hippocampus induced by cms. |
2019-06-06 |
2023-08-13 |
mouse |
| Sepideh Sadraie, Zahra Kiasalari, Mohadeseh Razavian, Shekoofe Azimi, Ladan Sedighnejad, Siamak Afshin-Majd, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms. Metabolic brain disease. vol 34. issue 1. 2019-06-06. PMID:30456649. |
berberine also appropriately restored hippocampal 3-nitrotyrosine (3-nt), cyclooxygenase 2 (cox 2), glial fibrillary acidic protein (gfap), sirtuin 1, and mitogen-activated protein kinase (p38 mapk) with no significant alteration of brain-derived neurotrophic factor (bdnf). |
2019-06-06 |
2023-08-13 |
rat |
| Sebahattin Karabulut, Keziban Korkmaz Bayramov, Ruslan Bayramov, Fadime Ozdemir, Tugba Topaloglu, Ergul Ergen, Kamile Yazgan, Ahmet Sevki Taskiran, Asuman Golgel. Effects of post-learning REM sleep deprivation on hippocampal plasticity-related genes and microRNA in mice. Behavioural brain research. vol 361. 2019-06-04. PMID:30594545. |
further, we found that the rem sd after training significantly changes the hippocampal expression of brain-derived neurotrophic factor (bdnf) mrna; however, it causes minimal difference in the hippocampal expressions of calcium-calmodulin-dependent protein kinase ii (camkii) and camp response-element-binding (creb). |
2019-06-04 |
2023-08-13 |
mouse |
| Xiuqin Li, Chao Liu, Bo Jiang, Kai Chen, Wenjuan Li, Hongze Wan. The antidepressant-like effects of sinomenine in mice: a behavioral and neurobiological characterization. Behavioural pharmacology. vol 29. issue 4. 2019-05-29. PMID:29035920. |
moreover, sinomenine fully restored the csds-induced decrease in the hippocampal bdnf signaling pathway, whereas a bdnf signaling inhibitor, but not a tryptophan hydroxylase inhibitor, blocked the antidepressant effects of sinomenine. |
2019-05-29 |
2023-08-13 |
mouse |
| Xiuqin Li, Chao Liu, Bo Jiang, Kai Chen, Wenjuan Li, Hongze Wan. The antidepressant-like effects of sinomenine in mice: a behavioral and neurobiological characterization. Behavioural pharmacology. vol 29. issue 4. 2019-05-29. PMID:29035920. |
in conclusion, sinomenine exerts antidepressant effects in mice by promoting the hippocampal bdnf signaling pathway. |
2019-05-29 |
2023-08-13 |
mouse |
| Bárbara Bruna, Pedro Lobos, Rodrigo Herrera-Molina, Cecilia Hidalgo, Andrea Paula-Lima, Tatiana Adasm. The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca Biochemical and biophysical research communications. vol 505. issue 1. 2019-05-28. PMID:30243728. |
the signaling pathways underlying bdnf-induced nrf2 hippocampal nuclear translocation involve ros, ryr-mediated ca the neurotrophin brain-derived neurotrophic factor (bdnf) induces complex neuronal signaling cascades that are critical for the cellular changes underlying synaptic plasticity. |
2019-05-28 |
2023-08-13 |
Not clear |
| Siamak Shahidi, Alireza Komaki, Reihaneh Sadeghian, Sara Soleimani As. Different doses of methamphetamine alter long-term potentiation, level of BDNF and neuronal apoptosis in the hippocampus of reinstated rats. The journal of physiological sciences : JPS. vol 69. issue 2. 2019-05-28. PMID:30680641. |
different doses of methamphetamine alter long-term potentiation, level of bdnf and neuronal apoptosis in the hippocampus of reinstated rats. |
2019-05-28 |
2023-08-13 |
rat |