| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
the aim of this study is to investigate the effects of long-chain noncoding rna plasmacytoma variant translocation 1 (pvt1) on the activation of astrocytes and the expression of brain-derived neurotrophic factor (bdnf) in hippocampus tissues of epileptic rats. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
successfully modeled rats were grouped, and their spatial learning and memory, neuronal loss, number of tdt-mediated dutp nick labeling (tunel)-positive cells, and the expression of cleaved-caspase-3, pro-caspase-3, bax, bcl-2, gfap, bdnf, tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β), il-6, axin, and cyclin d1 in hippocampus tissues were evaluated. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
silencing of pvt1 improved spatial learning and memory, decreased neuronal loss, decreased the number of tunel-positive cell, decreased the expression of cleaved-caspase-3 and bax while increased pro-caspase-3 and bcl-2 expression, decreased the expression of gfap, increased the expression of bdnf, decreased the expression of tnf-α, il-1β, and il-6, and decreased the expression of axin and cyclin d1 in hippocampus tissues in epileptic rats. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
our study provides evidence that the inhibition of pvt1 may decrease the loss of neurons, inhibit the activation of astrocytes, and increase the expression of bdnf in hippocampus by downregulating the wnt signaling pathway. |
2019-11-20 |
2023-08-13 |
rat |
| Ji-Xiao Zhu, Wei-Qiong Hu, Shu-Qi Dong, Li-Tao Yi, Jin-Xiang Zeng, Min L. Hippocampal BDNF signaling is required for the antidepressant effects of perillaldehyde. Pharmacological reports : PR. vol 71. issue 3. 2019-11-20. PMID:31003153. |
hippocampal bdnf signaling is required for the antidepressant effects of perillaldehyde. |
2019-11-20 |
2023-08-13 |
mouse |
| Masoumeh Sadeghinejad, Zahra Soltani, Mohammad Esmaeil Afzalpour, Mohammad Khaksari, Mohammad Pourranjba. What is the combined effect of intense intermittent exercise and Ginkgo biloba plant on the brain neurotrophic factors levels, and learning and memory in young rats? Pharmacological reports : PR. vol 71. issue 3. 2019-11-20. PMID:31009841. |
the present study was conducted to investigate the effect of intense intermittent exercise and ginkgo biloba on the hippocampal levels of brain-derived neurotrophic factor (bdnf) and neurotrophin-4 (nt-4) and also memory and learning in young rats. |
2019-11-20 |
2023-08-13 |
rat |
| S K Tahajjul Taufique, Abhilash Prabhat, Vinod Kuma. Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids. The European journal of neuroscience. vol 48. issue 9. 2019-11-14. PMID:30218624. |
concomitant reduction of immunoreactivity for dcx and bdnf suggested dlan-induced suppression of hippocampal neurogenesis and compromised neuronal health. |
2019-11-14 |
2023-08-13 |
Not clear |
| S K Tahajjul Taufique, Abhilash Prabhat, Vinod Kuma. Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids. The European journal of neuroscience. vol 48. issue 9. 2019-11-14. PMID:30218624. |
dlan also negatively influenced hippocampal expression of genes associated with depressive-like responses (bdnf, il-1β, tnfr1, nr4a2), but not of those associated with neuronal plasticity (egr1, creb, syngap, syn2, grin2a, grin2b), cellular oxidative stress (gst, sod3, cat1) and neuronal death (caspase2, caspase3, foxo3). |
2019-11-14 |
2023-08-13 |
Not clear |
| Stylianos Kosmidis, Alexandros Polyzos, Lucas Harvey, Mary Youssef, Christine A Denny, Alex Dranovsky, Eric R Kande. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell reports. vol 25. issue 4. 2019-11-14. PMID:30355501. |
by exploring how this protein regulates the genomic landscape of the hippocampal circuit, we find that rbap48 controls the expression of bdnf and gpr158 proteins, both critical components of osteocalcin (ocn) signaling in the mouse hippocampus. |
2019-11-14 |
2023-08-13 |
mouse |
| Sergio M G Solinas, Elke Edelmann, Volkmar Leßmann, Michele Miglior. A kinetic model for Brain-Derived Neurotrophic Factor mediated spike timing-dependent LTP. PLoS computational biology. vol 15. issue 4. 2019-11-12. PMID:31017891. |
the neurotrophin brain-derived neurotrophic factor (bdnf) is known to promote structural and functional synaptic plasticity in the hippocampus, the cerebral cortex, and many other brain areas. |
2019-11-12 |
2023-08-13 |
mouse |
| Asraa Faris Aldoghachi, Yin Sim Tor, Siti Zubaidah Redzun, Khairul Aiman Bin Lokman, Nurul Asyikin Abdul Razaq, Aishah Farhana Shahbudin, Ibrahim Mohamed Badamasi, Pike-See Cheah, Johnson Stanslas, Abhi Veerakumarasivam, Rozita Rosli, Normala Ibrahim, Munn Sann Lye, King-Hwa Lin. Screening of brain-derived neurotrophic factor (BDNF) single nucleotide polymorphisms and plasma BDNF levels among Malaysian major depressive disorder patients. PloS one. vol 14. issue 1. 2019-11-07. PMID:30677092. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin found in abundance in brain regions such as the hippocampus, cortex, cerebellum and basal forebrain. |
2019-11-07 |
2023-08-13 |
Not clear |
| Amal Ahmed Abd El-Fattah, Atef Tadros Fahim, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress. Brain research. vol 1701. 2019-11-04. PMID:30244113. |
cums exposure significantly decreased bdnf and β-catenin expression levels as well as increased gsk-3β expression level in hippocampus. |
2019-11-04 |
2023-08-13 |
rat |
| Amal Ahmed Abd El-Fattah, Atef Tadros Fahim, Nermin Abdel Hamid Sadik, Bassam Mohamed Al. Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable mild stress. Brain research. vol 1701. 2019-11-04. PMID:30244113. |
in conclusion, our study revealed that resveratrol and dmf exerted promising antidepressant-like effects in cums rats that are mediated in part by suppressing the neuroinflammation, oxidative stress, apoptosis and up-regulating hippocampal bdnf and β-catenin levels. |
2019-11-04 |
2023-08-13 |
rat |
| Minh Bao Huynh, Mohand Ouidir Ouidja, Sandrine Chantepie, Gilles Carpentier, Auriane Maïza, Ganlin Zhang, Joao Vilares, Rita Raisman-Vozari, Dulce Papy-Garci. Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau. PloS one. vol 14. issue 1. 2019-11-04. PMID:30608949. |
here, we show that total sulfated gags from hippocampus of alzheimer's disease have altered capacities to bind and potentiate the activities of growth factors including fgf-2, vegf, and bdnf while their capacity to bind to tau is remarkable increased. |
2019-11-04 |
2023-08-13 |
Not clear |
| André Spychala, Ulrich Rüthe. FTO affects hippocampal function by regulation of BDNF processing. PloS one. vol 14. issue 2. 2019-11-04. PMID:30730976. |
fto affects hippocampal function by regulation of bdnf processing. |
2019-11-04 |
2023-08-13 |
mouse |
| Deepti Sharma, Kalpana Kumari Barhwal, Surya Narayan Biswal, Anup Kumar Srivastava, Pushpendar Bhardwaj, Ashish Kumar, Om Prakash Chaurasia, Sunil Kumar Hot. Hypoxia-mediated alteration in cholesterol oxidation and raft dynamics regulates BDNF signalling and neurodegeneration in hippocampus. Journal of neurochemistry. vol 148. issue 2. 2019-10-28. PMID:30308090. |
hypoxia-mediated alteration in cholesterol oxidation and raft dynamics regulates bdnf signalling and neurodegeneration in hippocampus. |
2019-10-28 |
2023-08-13 |
rat |
| Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ry. An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:29643431. |
in addition to this decrease in depression-like behavior, brain-derived neurotrophic factor (bdnf) and neuropeptide y (npy) release increased in the hippocampus in response to mai treatment, but estradiol levels did not recover. |
2019-10-25 |
2023-08-13 |
rat |
| Su Yeon Seo, Ji-Young Moon, Suk-Yun Kang, O Sang Kwon, Sunoh Kwon, Se Kyun Bang, Soo Phil Kim, Kwang-Ho Choi, Yeonhee Ry. An estradiol-independent BDNF-NPY cascade is involved in the antidepressant effect of mechanical acupuncture instruments in ovariectomized rats. Scientific reports. vol 8. issue 1. 2019-10-25. PMID:29643431. |
furthermore, microinjection of the bdnf receptor antagonist ana-12 (0.1 pmol/1 μl) into the hippocampus before mai stimulation significantly suppressed the recovery of npy levels. |
2019-10-25 |
2023-08-13 |
rat |
| Vishnu N Thakare, Rajesh R Patil, Rajesh J Oswal, Valmik D Dhakane, Manoj K Aswar, Bhoomika M Pate. Therapeutic potential of silymarin in chronic unpredictable mild stress induced depressive-like behavior in mice. Journal of psychopharmacology (Oxford, England). vol 32. issue 2. 2019-10-24. PMID:29215318. |
in addition, neurobiochemical alterations, mainly monoamines, 5-ht, ne, da, neurotrophic factor bdnf, and cytokines, il-6, tnf-α, oxidant-antioxidant parameters by determining the malondialdehyde formation (an index of lipid peroxidation process), superoxide dismutase (sod) and catalase (cat) activity in hippocampus and cerebral cortex along with serum corticosterone were investigated. |
2019-10-24 |
2023-08-13 |
mouse |