| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto Ribes-Navarro, Mariam Atef, Sandra Sánchez-Sarasúa, María Teresa Beltrán-Bretones, Francisco Olucha-Bordonau, Ana María Sánchez-Pére. Abscisic Acid Supplementation Rescues High Fat Diet-Induced Alterations in Hippocampal Inflammation and IRSs Expression. Molecular neurobiology. vol 56. issue 1. 2019-04-01. PMID:29721854. |
as expected, we observed that a hfd increased hippocampal tumor necrosis factor alpha (tnfα) and amyloid precursor protein (app) levels while reducing brain-derived neurotrophic factor (bdnf) expression and neurogenesis. |
2019-04-01 |
2023-08-13 |
Not clear |
| Alberto Ribes-Navarro, Mariam Atef, Sandra Sánchez-Sarasúa, María Teresa Beltrán-Bretones, Francisco Olucha-Bordonau, Ana María Sánchez-Pére. Abscisic Acid Supplementation Rescues High Fat Diet-Induced Alterations in Hippocampal Inflammation and IRSs Expression. Molecular neurobiology. vol 56. issue 1. 2019-04-01. PMID:29721854. |
in this study, aba restored hfd-induced hippocampal alterations, including irs1 and irs2 expression, tnfα, app, and bdnf levels and neurogenesis. |
2019-04-01 |
2023-08-13 |
Not clear |
| J Bryce Ortiz, Julia M Anglin, Eshaan J Daas, Pooja R Paode, Kenji Nishimura, Cheryl D Conra. BDNF and TrkB Mediate the Improvement from Chronic Stress-induced Spatial Memory Deficits and CA3 Dendritic Retraction. Neuroscience. vol 388. 2019-03-29. PMID:30076998. |
we previously found that hippocampal brain-derived neurotrophic factor (bdnf) was necessary for spatial ability to improve following a post-stress rest period. |
2019-03-29 |
2023-08-13 |
rat |
| J Bryce Ortiz, Julia M Anglin, Eshaan J Daas, Pooja R Paode, Kenji Nishimura, Cheryl D Conra. BDNF and TrkB Mediate the Improvement from Chronic Stress-induced Spatial Memory Deficits and CA3 Dendritic Retraction. Neuroscience. vol 388. 2019-03-29. PMID:30076998. |
the following studies are the first to investigate the involvement of bdnf and its trkb receptor on the recovery process following the end of chronic stress, as it pertains to hippocampal dendritic retraction and spatial memory deficits. |
2019-03-29 |
2023-08-13 |
rat |
| J Bryce Ortiz, Julia M Anglin, Eshaan J Daas, Pooja R Paode, Kenji Nishimura, Cheryl D Conra. BDNF and TrkB Mediate the Improvement from Chronic Stress-induced Spatial Memory Deficits and CA3 Dendritic Retraction. Neuroscience. vol 388. 2019-03-29. PMID:30076998. |
in the first study, hippocampal bdnf was downregulated via rna interference and then hippocampal ca3 and ca1 dendritic complexity were evaluated following chronic stress and a post-stress rest period in male sprague-dawley rats. |
2019-03-29 |
2023-08-13 |
rat |
| J Bryce Ortiz, Julia M Anglin, Eshaan J Daas, Pooja R Paode, Kenji Nishimura, Cheryl D Conra. BDNF and TrkB Mediate the Improvement from Chronic Stress-induced Spatial Memory Deficits and CA3 Dendritic Retraction. Neuroscience. vol 388. 2019-03-29. PMID:30076998. |
downregulating hippocampal bdnf prevented the enhancement of ca3 apical dendritic complexity following the rest period. |
2019-03-29 |
2023-08-13 |
rat |
| J Bryce Ortiz, Julia M Anglin, Eshaan J Daas, Pooja R Paode, Kenji Nishimura, Cheryl D Conra. BDNF and TrkB Mediate the Improvement from Chronic Stress-induced Spatial Memory Deficits and CA3 Dendritic Retraction. Neuroscience. vol 388. 2019-03-29. PMID:30076998. |
these data demonstrate that hippocampal bdnf acting via its trkb receptor is necessary during the post-stress rest period in order to improve the impaired hippocampal structural and cognitive outcomes that occur in response to chronic stress. |
2019-03-29 |
2023-08-13 |
rat |
| Tobias Engeroff, Eszter Füzéki, Lutz Vogt, Johannes Fleckenstein, Sina Schwarz, Silke Matura, Ulrich Pilatus, Ralf Deichmann, Rainer Hellweg, Johannes Pantel, Winfried Banze. Is Objectively Assessed Sedentary Behavior, Physical Activity and Cardiorespiratory Fitness Linked to Brain Plasticity Outcomes in Old Age? Neuroscience. vol 388. 2019-03-29. PMID:30077618. |
brain plasticity outcomes included magnetic resonance spectroscopy (mrs)-based markers, quantitative imaging-based hippocampal volume and bdnf serum levels. |
2019-03-29 |
2023-08-13 |
human |
| Jie Gao, Bingrui Xiong, Bo Zhang, Shan Li, Niannian Huang, Gaofeng Zhan, Riyue Jiang, Ling Yang, Yeshun Wu, Liying Miao, Bin Zhu, Chun Yang, Ailin Lu. Sulforaphane Alleviates Lipopolysaccharide-induced Spatial Learning and Memory Dysfunction in Mice: The Role of BDNF-mTOR Signaling Pathway. Neuroscience. vol 388. 2019-03-29. PMID:30086367. |
the present study aimed to investigate the therapeutic effects of sulforaphane (sfn) on lipopolysaccharide (lps)-induced spatial learning and memory dysfunction, and tried to elucidate its relationship with the role of hippocampal brain-derived neurotrophic factor (bdnf)-mammalian target of rapamycin (mtor) signaling pathway. |
2019-03-29 |
2023-08-13 |
mouse |
| Joel E Soler, Alfred J Robison, Antonio A Núñez, Lily Ya. Light modulates hippocampal function and spatial learning in a diurnal rodent species: A study using male nile grass rat (Arvicanthis niloticus). Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29251803. |
in addition to the behavioral changes, grass rats in the dimld condition exhibited reduced expression of brain-derived neurotrophic factor (bdnf) in the hippocampus, most notably in the ca1 subregion. |
2019-03-26 |
2023-08-13 |
human |
| Joel E Soler, Alfred J Robison, Antonio A Núñez, Lily Ya. Light modulates hippocampal function and spatial learning in a diurnal rodent species: A study using male nile grass rat (Arvicanthis niloticus). Hippocampus. vol 28. issue 3. 2019-03-26. PMID:29251803. |
when dimld animals were transferred to the brld condition for 4 weeks, the hippocampal bdnf and dendritic spine density significantly increased. |
2019-03-26 |
2023-08-13 |
human |
| Luis E Rosas-Vidal, Valeria Lozada-Miranda, Yisel Cantres-Rosario, Alexis Vega-Medina, Loyda Melendez, Gregory J Quir. Alteration of BDNF in the medial prefrontal cortex and the ventral hippocampus impairs extinction of avoidance. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 13. 2019-03-26. PMID:30127343. |
alteration of bdnf in the medial prefrontal cortex and the ventral hippocampus impairs extinction of avoidance. |
2019-03-26 |
2023-08-13 |
Not clear |
| Luis E Rosas-Vidal, Valeria Lozada-Miranda, Yisel Cantres-Rosario, Alexis Vega-Medina, Loyda Melendez, Gregory J Quir. Alteration of BDNF in the medial prefrontal cortex and the ventral hippocampus impairs extinction of avoidance. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 13. 2019-03-26. PMID:30127343. |
by combining retrograde tracers with bdnf immunohistochemistry, we show that extinction of avoidance increases bdnf expression in ventral hippocampal (vhpc) neurons, but not amygdala neurons, projecting to pl and il. |
2019-03-26 |
2023-08-13 |
Not clear |
| Jitao Li, Youhong Li, Yaxin Sun, Han Wang, Xiao Liu, Yingying Zhao, Hongli Wang, Yun'ai Su, Tianmei S. Chronic mild corticosterone exposure during adolescence enhances behaviors and upregulates neuroplasticity-related proteins in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 89. 2019-03-25. PMID:30392783. |
they also showed increased expression of hippocampal neuroplasticity-related proteins, including bdnf, nectin3, and ampa receptor subunits. |
2019-03-25 |
2023-08-13 |
rat |
| Alana Gomes de Souza, Adriano José Maia Chaves Filho, João Victor Souza Oliveira, Denia Alves Albuquerque de Souza, Iardja Stéfane Lopes, Michele Albuquerque Jales de Carvalho, Klistenes Alves de Lima, Francisca Cléa Florenço Sousa, Silvânia Maria Mendes Vasconcelos, Danielle Macedo, Marta Maria de França Fontele. Prevention of pentylenetetrazole-induced kindling and behavioral comorbidities in mice by levetiracetam combined with the GLP-1 agonist liraglutide: Involvement of brain antioxidant and BDNF upregulating properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-03-25. PMID:30399578. |
lira or lev + lira increased hippocampal bdnf levels. |
2019-03-25 |
2023-08-13 |
mouse |
| Shouhei Miyazaki, Hirotaka Oikawa, Hideo Takekoshi, Masako Hoshizaki, Masato Ogata, Takahiko Fujikaw. Anxiolytic Effects of Molecules (Basel, Switzerland). vol 24. issue 1. 2019-03-22. PMID:30602695. |
in addition, stress induces glucocorticoids and changes the hippocampal brain-derived neurotrophic factor (bdnf) expression levels. |
2019-03-22 |
2023-08-13 |
Not clear |
| Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
levels of aβ40, aβ42 and bdnf were assessed in brain hippocampal homogenates for correlative purposes. |
2019-03-21 |
2023-08-13 |
rat |
| Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
these behavioural changes were associated with increased aβ depositions and lowered bdnf levels in brain hippocampal homogenates. |
2019-03-21 |
2023-08-13 |
rat |
| Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
the icv-stz induced elevations in aβ40 and aβ42 and reduced levels of bdnf in hippocampal homogenates were also attenuated after gsno treatment in these rats. |
2019-03-21 |
2023-08-13 |
rat |
| Wataru Ito, Howard Huang, Vanessa Brayman, Alexei Morozo. Impaired social contacts with familiar anesthetized conspecific in CA3-restricted brain-derived neurotrophic factor knockout mice. Genes, brain, and behavior. vol 18. issue 1. 2019-03-21. PMID:30120813. |
we then applied this test to highly aggressive mice with a hippocampal ca3-restricted knockout (ko) of brain-derived neurotrophic factor (bdnf), in which aggression may mask other social behaviors. |
2019-03-21 |
2023-08-13 |
mouse |