| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal glucocorticoid receptor dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
| Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
moreover, apelin-13 ameliorated hypothalamic-pituitary-adrenal (hpa) axis hyperactivity, and hippocampal bdnf expression deficit and glucocorticoid receptor (gr) nucleus translocation hypoactivity in chronic stressed rats. |
2019-03-21 |
2023-08-13 |
rat |
| Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
these results suggest that apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal gr dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
| Bo Ren, Tian Yuan, Zhijun Diao, Chenxi Zhang, Zhigang Liu, Xuebo Li. Protective effects of sesamol on systemic oxidative stress-induced cognitive impairments via regulation of Nrf2/Keap1 pathway. Food & function. vol 9. issue 11. 2019-03-20. PMID:30375618. |
meanwhile, sesamol ameliorated neuronal damage and improved bdnf level in rat hippocampus. |
2019-03-20 |
2023-08-13 |
mouse |
| Kamilla Blecharz-Klin, Adriana Wawer, Katarzyna Jawna-Zboińska, Justyna Pyrzanowska, Agnieszka Piechal, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Early paracetamol exposure decreases brain-derived neurotrophic factor (BDNF) in striatum and affects social behaviour and exploration in rats. Pharmacology, biochemistry, and behavior. vol 168. 2019-03-15. PMID:29545027. |
quantification of brain-derived neurotrophic factor (bdnf) was determined in prefrontal cortex, hippocampus and striatum using enzyme-linked immunosorbent assay (elisa). |
2019-03-15 |
2023-08-13 |
rat |
| Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
the bdnf/trkb immunohistochemical expression in the hippocampus was measured and serum bdnf was determined. |
2019-03-15 |
2023-08-13 |
rat |
| Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
lacosamide induced a dose-dependent reduction of the hippocampal expression of bdnf and its receptor trkb. |
2019-03-15 |
2023-08-13 |
rat |
| G Aleph Prieto, Liqi Tong, Erica D Smith, Carl W Cotma. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemical research. vol 44. issue 1. 2019-03-14. PMID:29619614. |
we also found that il-18 does not impair cltp or brain-derived neurotrophic factor (bdnf) signaling in primary hippocampal neuronal cultures. |
2019-03-14 |
2023-08-13 |
mouse |
| Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
changes in oxidative stress biomarkers, brain derived neuroptrophic factor (bdnf), and epigenetics (histones) in the hippocampus following treatments were measured using enzymatic assays. |
2019-03-12 |
2023-08-13 |
rat |
| Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
furthermore, ptx normalized sps induced changes in the hippocampus gsh/gssg ratio, activity of catalase, and glutathione peroxidase (gpx), bdnf, and certain histones levels. |
2019-03-12 |
2023-08-13 |
rat |
| Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
in conclusion, the sps model of ptsd-like behavior induced memory impairment, whereas ptx prevented this impairment possibly through normalizing antioxidant mechanisms, bdnf and epigenetic changes in the hippocampus. |
2019-03-12 |
2023-08-13 |
rat |
| Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
beta-hydroxybutyrate promotes the expression of bdnf in hippocampal neurons under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |
| Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
here we demonstrated that bhba administration induced the expression of bdnf in the hippocampus of mice fed with normal diet. |
2019-03-11 |
2023-08-13 |
mouse |
| Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
in vitro experiment results also showed that 0.02-2 mm bhba significantly increased bdnf expression in both the primary hippocampal neurons and the hippocampus neuron cell line ht22 under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |
| Marwa M Nagib, Mariane G Tadros, Rania M Rahmo, Nagwa Ali Sabri, Amani E Khalifa, Somaia I Masou. Ameliorative Effects of α-Tocopherol and/or Coenzyme Q10 on Phenytoin-Induced Cognitive Impairment in Rats: Role of VEGF and BDNF-TrkB-CREB Pathway. Neurotoxicity research. vol 35. issue 2. 2019-03-11. PMID:30374909. |
moreover, vegf, bdnf, trkb, and creb gene expression levels in the hippocampus and prefrontal cortex were estimated using rt-pcr. |
2019-03-11 |
2023-08-13 |
rat |
| Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
in the hippocampus of female offspring, bpa exposure resulted in hypermethylation of the putative 5' promoter region of bdnf, while ee exposure induced hypomethylation. |
2019-03-08 |
2023-08-13 |
rat |
| Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
hippocampal bdnf expression in females showed a weak negative association with sniffing correct hole in barnes maze. |
2019-03-08 |
2023-08-13 |
rat |
| Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria G Corda, Osvaldo Giorgi, Marina Quart. Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression. International journal of molecular sciences. vol 19. issue 12. 2019-03-08. PMID:30477252. |
effect of acute stress on the expression of bdnf, trkb, and psa-ncam in the hippocampus of the roman rats: a genetic model of vulnerability/resistance to stress-induced depression. |
2019-03-08 |
2023-08-13 |
rat |
| Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria G Corda, Osvaldo Giorgi, Marina Quart. Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression. International journal of molecular sciences. vol 19. issue 12. 2019-03-08. PMID:30477252. |
in the view of the key role played by the neurotrophic factors and neuronal plasticity, in the pathophysiology of depression, we aimed at assessing the effects of acute stress, i.e., forced swimming (fs), on the expression of brain-derived neurotrophic factor (bdnf), its trkb receptor, and the polysialilated-neural cell adhesion molecule (psa-ncam), in the dorsal (dhc) and ventral (vhc) hippocampus of the rha and the rla rats, by means of western blot and immunohistochemical assays. |
2019-03-08 |
2023-08-13 |
rat |
| Hiroshi Maejima, Shuta Ninuma, Akane Okuda, Takahiro Inoue, Masataka Hayash. Exercise and low-level GABA Neuroscience letters. vol 685. 2019-03-07. PMID:30037768. |
exercise and low-level gaba aerobic exercise is known to increase expression of brain-derived neurotrophic factor (bdnf) in the hippocampus and to improve cognitive function. |
2019-03-07 |
2023-08-13 |
Not clear |