Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Alana Gomes de Souza, Adriano José Maia Chaves Filho, João Victor Souza Oliveira, Denia Alves Albuquerque de Souza, Iardja Stéfane Lopes, Michele Albuquerque Jales de Carvalho, Klistenes Alves de Lima, Francisca Cléa Florenço Sousa, Silvânia Maria Mendes Vasconcelos, Danielle Macedo, Marta Maria de França Fontele. Prevention of pentylenetetrazole-induced kindling and behavioral comorbidities in mice by levetiracetam combined with the GLP-1 agonist liraglutide: Involvement of brain antioxidant and BDNF upregulating properties. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 109. 2019-03-25. PMID:30399578. |
lira or lev + lira increased hippocampal bdnf levels. |
2019-03-25 |
2023-08-13 |
mouse |
Shouhei Miyazaki, Hirotaka Oikawa, Hideo Takekoshi, Masako Hoshizaki, Masato Ogata, Takahiko Fujikaw. Anxiolytic Effects of Molecules (Basel, Switzerland). vol 24. issue 1. 2019-03-22. PMID:30602695. |
in addition, stress induces glucocorticoids and changes the hippocampal brain-derived neurotrophic factor (bdnf) expression levels. |
2019-03-22 |
2023-08-13 |
Not clear |
Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
levels of aβ40, aβ42 and bdnf were assessed in brain hippocampal homogenates for correlative purposes. |
2019-03-21 |
2023-08-13 |
rat |
Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
these behavioural changes were associated with increased aβ depositions and lowered bdnf levels in brain hippocampal homogenates. |
2019-03-21 |
2023-08-13 |
rat |
Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
the icv-stz induced elevations in aβ40 and aβ42 and reduced levels of bdnf in hippocampal homogenates were also attenuated after gsno treatment in these rats. |
2019-03-21 |
2023-08-13 |
rat |
Wataru Ito, Howard Huang, Vanessa Brayman, Alexei Morozo. Impaired social contacts with familiar anesthetized conspecific in CA3-restricted brain-derived neurotrophic factor knockout mice. Genes, brain, and behavior. vol 18. issue 1. 2019-03-21. PMID:30120813. |
we then applied this test to highly aggressive mice with a hippocampal ca3-restricted knockout (ko) of brain-derived neurotrophic factor (bdnf), in which aggression may mask other social behaviors. |
2019-03-21 |
2023-08-13 |
mouse |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal glucocorticoid receptor dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
moreover, apelin-13 ameliorated hypothalamic-pituitary-adrenal (hpa) axis hyperactivity, and hippocampal bdnf expression deficit and glucocorticoid receptor (gr) nucleus translocation hypoactivity in chronic stressed rats. |
2019-03-21 |
2023-08-13 |
rat |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
these results suggest that apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal gr dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
Bo Ren, Tian Yuan, Zhijun Diao, Chenxi Zhang, Zhigang Liu, Xuebo Li. Protective effects of sesamol on systemic oxidative stress-induced cognitive impairments via regulation of Nrf2/Keap1 pathway. Food & function. vol 9. issue 11. 2019-03-20. PMID:30375618. |
meanwhile, sesamol ameliorated neuronal damage and improved bdnf level in rat hippocampus. |
2019-03-20 |
2023-08-13 |
mouse |
Kamilla Blecharz-Klin, Adriana Wawer, Katarzyna Jawna-Zboińska, Justyna Pyrzanowska, Agnieszka Piechal, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Early paracetamol exposure decreases brain-derived neurotrophic factor (BDNF) in striatum and affects social behaviour and exploration in rats. Pharmacology, biochemistry, and behavior. vol 168. 2019-03-15. PMID:29545027. |
quantification of brain-derived neurotrophic factor (bdnf) was determined in prefrontal cortex, hippocampus and striatum using enzyme-linked immunosorbent assay (elisa). |
2019-03-15 |
2023-08-13 |
rat |
Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
the bdnf/trkb immunohistochemical expression in the hippocampus was measured and serum bdnf was determined. |
2019-03-15 |
2023-08-13 |
rat |
Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
lacosamide induced a dose-dependent reduction of the hippocampal expression of bdnf and its receptor trkb. |
2019-03-15 |
2023-08-13 |
rat |
G Aleph Prieto, Liqi Tong, Erica D Smith, Carl W Cotma. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemical research. vol 44. issue 1. 2019-03-14. PMID:29619614. |
we also found that il-18 does not impair cltp or brain-derived neurotrophic factor (bdnf) signaling in primary hippocampal neuronal cultures. |
2019-03-14 |
2023-08-13 |
mouse |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
changes in oxidative stress biomarkers, brain derived neuroptrophic factor (bdnf), and epigenetics (histones) in the hippocampus following treatments were measured using enzymatic assays. |
2019-03-12 |
2023-08-13 |
rat |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
furthermore, ptx normalized sps induced changes in the hippocampus gsh/gssg ratio, activity of catalase, and glutathione peroxidase (gpx), bdnf, and certain histones levels. |
2019-03-12 |
2023-08-13 |
rat |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
in conclusion, the sps model of ptsd-like behavior induced memory impairment, whereas ptx prevented this impairment possibly through normalizing antioxidant mechanisms, bdnf and epigenetic changes in the hippocampus. |
2019-03-12 |
2023-08-13 |
rat |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
beta-hydroxybutyrate promotes the expression of bdnf in hippocampal neurons under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
here we demonstrated that bhba administration induced the expression of bdnf in the hippocampus of mice fed with normal diet. |
2019-03-11 |
2023-08-13 |
mouse |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
in vitro experiment results also showed that 0.02-2 mm bhba significantly increased bdnf expression in both the primary hippocampal neurons and the hippocampus neuron cell line ht22 under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |