| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marwa M Nagib, Mariane G Tadros, Rania M Rahmo, Nagwa Ali Sabri, Amani E Khalifa, Somaia I Masou. Ameliorative Effects of α-Tocopherol and/or Coenzyme Q10 on Phenytoin-Induced Cognitive Impairment in Rats: Role of VEGF and BDNF-TrkB-CREB Pathway. Neurotoxicity research. vol 35. issue 2. 2019-03-11. PMID:30374909. |
moreover, vegf, bdnf, trkb, and creb gene expression levels in the hippocampus and prefrontal cortex were estimated using rt-pcr. |
2019-03-11 |
2023-08-13 |
rat |
| Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
in the hippocampus of female offspring, bpa exposure resulted in hypermethylation of the putative 5' promoter region of bdnf, while ee exposure induced hypomethylation. |
2019-03-08 |
2023-08-13 |
rat |
| Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
hippocampal bdnf expression in females showed a weak negative association with sniffing correct hole in barnes maze. |
2019-03-08 |
2023-08-13 |
rat |
| Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria G Corda, Osvaldo Giorgi, Marina Quart. Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression. International journal of molecular sciences. vol 19. issue 12. 2019-03-08. PMID:30477252. |
effect of acute stress on the expression of bdnf, trkb, and psa-ncam in the hippocampus of the roman rats: a genetic model of vulnerability/resistance to stress-induced depression. |
2019-03-08 |
2023-08-13 |
rat |
| Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria G Corda, Osvaldo Giorgi, Marina Quart. Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression. International journal of molecular sciences. vol 19. issue 12. 2019-03-08. PMID:30477252. |
in the view of the key role played by the neurotrophic factors and neuronal plasticity, in the pathophysiology of depression, we aimed at assessing the effects of acute stress, i.e., forced swimming (fs), on the expression of brain-derived neurotrophic factor (bdnf), its trkb receptor, and the polysialilated-neural cell adhesion molecule (psa-ncam), in the dorsal (dhc) and ventral (vhc) hippocampus of the rha and the rla rats, by means of western blot and immunohistochemical assays. |
2019-03-08 |
2023-08-13 |
rat |
| Hiroshi Maejima, Shuta Ninuma, Akane Okuda, Takahiro Inoue, Masataka Hayash. Exercise and low-level GABA Neuroscience letters. vol 685. 2019-03-07. PMID:30037768. |
exercise and low-level gaba aerobic exercise is known to increase expression of brain-derived neurotrophic factor (bdnf) in the hippocampus and to improve cognitive function. |
2019-03-07 |
2023-08-13 |
Not clear |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Mia. Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30365051. |
it is not known whether brain‑derived neurotrophic factor (bdnf) protects hippocampal neurons from high glucose‑induced apoptosis and/or synaptic plasticity dysfunction. |
2019-03-05 |
2023-08-13 |
rat |
| Yuan Zhong, Yitong Zhu, Ting He, Wei Li, Qinjie Li, Ya Mia. Brain-derived neurotrophic factor inhibits hyperglycemia-induced apoptosis and downregulation of synaptic plasticity-related proteins in hippocampal neurons via the PI3K/Akt pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30365051. |
the present study aimed to assess whether bdnf exerted a neuroprotective effect in rat hippocampal neurons exposed to high glucose and examine the underlying mechanisms. |
2019-03-05 |
2023-08-13 |
rat |
| Catherine Fleitas, Gerard Piñol-Ripoll, Pau Marfull, Daniel Rocandio, Isidro Ferrer, Claire Rampon, Joaquim Egea, Carme Espine. proBDNF is modified by advanced glycation end products in Alzheimer's disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing. Molecular brain. vol 11. issue 1. 2019-03-04. PMID:30428894. |
contrarily to bdnf, the precursor form of bdnf (probdnf) induces apoptosis through the specific interaction with p75 and its co-receptor, sortilin.we used hippocampal tissue and cerebrospinal fluid from ad patients and controls. |
2019-03-04 |
2023-08-13 |
mouse |
| Wei Pan, Guang-Fen Zhang, Hui-Hui Li, Mu-Huo Ji, Zhi-Qiang Zhou, Kuan-Yu Li, Jian-Jun Yan. Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression. Neuroreport. vol 29. issue 10. 2019-02-27. PMID:29742620. |
it is noteworthy that ketamine (10 mg/kg) relieved neuropathic pain-induced depressive behaviors and restored alterations of bdnf and nls in the mpfc and the hippocampus at 24 h and 72 h after the administration of ketamine, but only restored bdnf in the acc. |
2019-02-27 |
2023-08-13 |
rat |
| Dandan Liu, Yilu Ye, Linhao Xu, Wenxia Yuan, Qi Zhan. Icariin and mesenchymal stem cells synergistically promote angiogenesis and neurogenesis after cerebral ischemia via PI3K and ERK1/2 pathways. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-27. PMID:30245466. |
the combined therapy increased expression of vegf and bdnf to a maximum through activating pi3k and erk1/2 pathways in the hippocampus and frontal cortex in response to transient mcao. |
2019-02-27 |
2023-08-13 |
rat |
| C R A F Diniz, C Becari, A Lesnikova, C Biojone, M C O Salgado, H C Salgado, L B M Resstel, F S Guimarães, E Castrén, P C Casarotto, S R L Joc. Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29383685. |
increased levels of bdnf were found in the prefrontal cortex but not in the hippocampus of ela2ko mice compared to wt. |
2019-02-26 |
2023-08-13 |
mouse |
| Miguel Ángel Luján, Adriana Castro-Zavala, Laia Alegre-Zurano, Olga Valverd. Repeated Cannabidiol treatment reduces cocaine intake and modulates neural proliferation and CB1R expression in the mouse hippocampus. Neuropharmacology. vol 143. 2019-02-25. PMID:30273593. |
in parallel, cbd increased expression of type 1 cannabinoid receptor, mapk-creb phosphorylation, bdnf expression, and neural cell proliferation in the hippocampus, and reduced the glua1/2 ampa subunit receptor ratio in the striatum. |
2019-02-25 |
2023-08-13 |
mouse |
| Stine Normann Hansen, David Højland Ipsen, Anne Marie Schou-Pedersen, Jens Lykkesfeldt, Pernille Tveden-Nybor. Long term Westernized diet leads to region-specific changes in brain signaling mechanisms. Neuroscience letters. vol 676. 2019-02-22. PMID:29655945. |
here we investigate the effects of dyslipidemia induced by two high fat diets with or without high sucrose on hippocampal and frontal cortical oxidative stress, brain-derived neurotrophic factor (bdnf) and down-stream markers of synaptic plasticity, as well as alterations in monoaminergic neurotransmitter levels. |
2019-02-22 |
2023-08-13 |
Not clear |
| Kristen R Maynard, John W Hobbs, Mahima Sukumar, Alisha S Kardian, Dennisse V Jimenez, Robert J Schloesser, Keri Martinowic. Bdnf mRNA splice variants differentially impact CA1 and CA3 dendrite complexity and spine morphology in the hippocampus. Brain structure & function. vol 222. issue 7. 2019-02-21. PMID:28324222. |
bdnf mrna splice variants differentially impact ca1 and ca3 dendrite complexity and spine morphology in the hippocampus. |
2019-02-21 |
2023-08-13 |
mouse |
| Kristen R Maynard, John W Hobbs, Mahima Sukumar, Alisha S Kardian, Dennisse V Jimenez, Robert J Schloesser, Keri Martinowic. Bdnf mRNA splice variants differentially impact CA1 and CA3 dendrite complexity and spine morphology in the hippocampus. Brain structure & function. vol 222. issue 7. 2019-02-21. PMID:28324222. |
brain-derived neurotrophic factor (bdnf) is an activity-dependent neurotrophin critical for neuronal plasticity in the hippocampus. |
2019-02-21 |
2023-08-13 |
mouse |
| Kristen R Maynard, John W Hobbs, Mahima Sukumar, Alisha S Kardian, Dennisse V Jimenez, Robert J Schloesser, Keri Martinowic. Bdnf mRNA splice variants differentially impact CA1 and CA3 dendrite complexity and spine morphology in the hippocampus. Brain structure & function. vol 222. issue 7. 2019-02-21. PMID:28324222. |
while individual bdnf 5'utr transcripts influence dendrite morphology in cultured hippocampal neurons, it is unknown whether bdnf splice variants impact dendrite arborization in functional classes of neurons in the intact hippocampus. |
2019-02-21 |
2023-08-13 |
mouse |
| Mikhail Stepanichev, Anna Manolova, Danil Peregud, Mikhail Onufriev, Sofia Freiman, Viktor Aniol, Yulia Moiseeva, Margarita Novikova, Natalia Lazareva, Natalia Gulyaev. Specific Activity Features in the Forced Swim Test: Brain Neurotrophins and Development of Stress-induced Depressive-like Behavior in Rats. Neuroscience. vol 375. 2019-02-21. PMID:29438801. |
the low immobile (li) and high immobile (hi) rats demonstrated elusive differences in expression of bdnf exvi mrna and trka mrna which was higher in the hippocampus and frontal cortex, respectively, of hi rats as compared to li animals. |
2019-02-21 |
2023-08-13 |
rat |
| Mikhail Stepanichev, Anna Manolova, Danil Peregud, Mikhail Onufriev, Sofia Freiman, Viktor Aniol, Yulia Moiseeva, Margarita Novikova, Natalia Lazareva, Natalia Gulyaev. Specific Activity Features in the Forced Swim Test: Brain Neurotrophins and Development of Stress-induced Depressive-like Behavior in Rats. Neuroscience. vol 375. 2019-02-21. PMID:29438801. |
in hippocampus of stressed li rats, the contents of total bdnf mrna decreased. |
2019-02-21 |
2023-08-13 |
rat |
| Mikhail Stepanichev, Anna Manolova, Danil Peregud, Mikhail Onufriev, Sofia Freiman, Viktor Aniol, Yulia Moiseeva, Margarita Novikova, Natalia Lazareva, Natalia Gulyaev. Specific Activity Features in the Forced Swim Test: Brain Neurotrophins and Development of Stress-induced Depressive-like Behavior in Rats. Neuroscience. vol 375. 2019-02-21. PMID:29438801. |
in hippocampus of stressed hi rats, the content of trka mrna increased whereas in frontal cortex, the content of bdnf exon i mrna decreased in both li and hi rats. |
2019-02-21 |
2023-08-13 |
rat |