| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Guan Chen, Jia-Xuan Zheng, Xi Xu, Yu-Ming Hu, Yu-Min M. Hippocampal FXR plays a role in the pathogenesis of depression: A preliminary study based on lentiviral gene modulation. Psychiatry research. vol 264. 2018-12-31. PMID:29677620. |
overexpression of hippocampal fxr induced notable depressive-like behaviors and decreased expression of brain-derived neurotrophic factor (bdnf) in naïve rats, while knockdown of hippocampal fxr fully prevented the effects of cums on rat behaviors and hippocampal bdnf expression. |
2018-12-31 |
2023-08-13 |
rat |
| Simin Afshar, Siamak Shahidi, Ali Haeri Rohani, Alireza Komaki, Sara Soleimani As. The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats. Psychopharmacology. vol 235. issue 10. 2018-12-31. PMID:30027497. |
the effect of nad-299 and tcb-2 on learning and memory, hippocampal bdnf levels and amyloid plaques in streptozotocin-induced memory deficits in male rats. |
2018-12-31 |
2023-08-13 |
rat |
| Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
within the hippocampus, mediators of neural plasticity such as brain-derived neurotrophic factor (bdnf), can influence and be influenced by cort, hippocampus-associated behaviors and regulatory epigenetic modification enzymes. |
2018-12-31 |
2023-08-13 |
Not clear |
| Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
here, we investigated whether individuals and populations colonizing a new geographic range, senegal, vary in the expression of bdnf and dna methyltransferases (dnmts) within the hippocampus and the release of cort in response to a stressor. |
2018-12-31 |
2023-08-13 |
Not clear |
| Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
we surveyed three populations across senegal, predicting that hippocampal bdnf and dnmt expression would be highest at the range-edge, and that bdnf and dnmt would be inversely related to one another, but would each positively covary with cort within individuals. |
2018-12-31 |
2023-08-13 |
Not clear |
| J-L Rault, A J Lawrence, C R Ralp. Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs. Domestic animal endocrinology. vol 65. 2018-12-27. PMID:30007130. |
higher bdnf concentration is ultimately linked to higher stress resilience, and bdnf in the hippocampus enhances learning and memory. |
2018-12-27 |
2023-08-13 |
Not clear |
| Timothy M Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A Baccarelli, Liqiong Gu. The effect of morphine upon DNA methylation in ten regions of the rat brain. Epigenetics. vol 12. issue 12. 2018-12-21. PMID:29111854. |
we observed differential methylation of bdnf and il6 in the pons, nr3c1 in the cerebellum, and il1b in the hippocampus in response to acute morphine exposure (all p value < 0.05). |
2018-12-21 |
2023-08-13 |
rat |
| Timothy M Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A Baccarelli, Liqiong Gu. The effect of morphine upon DNA methylation in ten regions of the rat brain. Epigenetics. vol 12. issue 12. 2018-12-21. PMID:29111854. |
chronic exposure was associated with differential methylation of bdnf and comt in the pons, nr3c1 in the hippocampus and il1b in the medulla oblongata (all p value < 0.05). |
2018-12-21 |
2023-08-13 |
rat |
| Kenichi Kawahori, Koshi Hashimoto, Xunmei Yuan, Kazutaka Tsujimoto, Nozomi Hanzawa, Miho Hamaguchi, Saori Kase, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Yasuyo Nakajima, Nobuyuki Shibusawa, Masanobu Yamada, Yoshihiro Ogaw. Mild Maternal Hypothyroxinemia During Pregnancy Induces Persistent DNA Hypermethylation in the Hippocampal Brain-Derived Neurotrophic Factor Gene in Mouse Offspring. Thyroid : official journal of the American Thyroid Association. vol 28. issue 3. 2018-12-21. PMID:29415629. |
this may be due to the persistent reduced expression of the hippocampal brain-derived neurotrophic factor gene bdnf, which plays a crucial role in cns development. |
2018-12-21 |
2023-08-13 |
mouse |
| Weike Chen, Tingting Liang, Wenwen Zuo, Xin Wu, Zibo Shen, Fang Wang, Cunyu Li, Yunfeng Zheng, Guoping Pen. Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-12-18. PMID:29957471. |
compared to senescence-accelerated-resistant mouse 1 (samr1) mice, samp8 mice exhibited conspicuous declines in spatial memory abilities and brain-derived neurotrophic factor (bdnf) and tyrosine kinase receptors (trkb) level in hippocampus; increased aβ deposition, β-secretase (bace1) level, microglia activation and inflammatory factors, including interleukin-1β (il-1β), interleukin-6 (il-6) and tumor necrosis factor α (tnf-α) in the brain. |
2018-12-18 |
2023-08-13 |
mouse |
| Tengfei Zhao, Yingxue Fu, Hao Sun, Xiaoquan Li. Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia. IUBMB life. vol 70. issue 1. 2018-12-17. PMID:29247598. |
at the end of the experiments, the hippocampal biomarkers brain-derived neurotrophic factor (bdnf), monocyte chemotactic protein 1 (mcp-1), and homocysteine (hcy) were examined. |
2018-12-17 |
2023-08-13 |
rat |
| Fernanda Nunes, Daniela Pochmann, Amanda Staldoni Almeida, Daniela Melo Marques, Lisiane de Oliveira Porciúncul. Differential Behavioral and Biochemical Responses to Caffeine in Male and Female Rats from a Validated Model of Attention Deficit and Hyperactivity Disorder. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29557061. |
shr rats from both sexes presented increases in the bdnf, truncated and phospho-trkb receptors and also phospho-creb levels in the hippocampus. |
2018-12-17 |
2023-08-13 |
rat |
| Fernanda Nunes, Daniela Pochmann, Amanda Staldoni Almeida, Daniela Melo Marques, Lisiane de Oliveira Porciúncul. Differential Behavioral and Biochemical Responses to Caffeine in Male and Female Rats from a Validated Model of Attention Deficit and Hyperactivity Disorder. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29557061. |
besides, our data revealed that caffeine intake since childhood attenuated behavioral alterations in the adhd model associated with changes in bdnf and trkb receptors in the hippocampus. |
2018-12-17 |
2023-08-13 |
rat |
| Willy Chou, Yu-Fan Liu, Cheng-Hsien Lin, Mao-Tsun Lin, Chi-Chun Chen, Wen-Pin Liu, Ching-Ping Chang, Chung-Ching Chi. Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29574629. |
in addition to increasing hippocampal and cortical expression of hsp20, brain-derived neurotrophic factor (bdnf), and the tropomyosin receptor kinase b (trkb) ratio, pe rehabilitation significantly attenuated brain contusion and improved cognitive deficits in the rat model. |
2018-12-17 |
2023-08-13 |
rat |
| Willy Chou, Yu-Fan Liu, Cheng-Hsien Lin, Mao-Tsun Lin, Chi-Chun Chen, Wen-Pin Liu, Ching-Ping Chang, Chung-Ching Chi. Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29574629. |
furthermore, reducing hippocampal and cortical expression of hsp20 with an intracerebral injection of psuper hsp20 small interfering rna significantly diminished the pe-induced overexpression of hippocampal and cortical bdnf and the trkb ratio and also reversed the beneficial effect of pe in reducing neurotrauma and the cognitive deficits. |
2018-12-17 |
2023-08-13 |
rat |
| Willy Chou, Yu-Fan Liu, Cheng-Hsien Lin, Mao-Tsun Lin, Chi-Chun Chen, Wen-Pin Liu, Ching-Ping Chang, Chung-Ching Chi. Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29574629. |
a positive pearson correlation was found between hsp20 and bdnf, as well as between hsp20 and trkb, in the hippocampal and cortical tissues. |
2018-12-17 |
2023-08-13 |
rat |
| Yvan Peterschmitt, Souleymane Abdoul-Azize, Babar Murtaza, Marie Barbier, Amira Sayed Khan, Jean-Louis Millot, Naim Akhtar Kha. Fatty Acid Lingual Application Activates Gustatory and Reward Brain Circuits in the Mouse. Nutrients. vol 10. issue 9. 2018-12-17. PMID:30200577. |
interestingly, we noticed a high expression of bdnf, zif-268, and glut-1 mrna in the arcuate nucleus (arc) and hippocampus (hipp), where neuronal activation leads to memory formation. |
2018-12-17 |
2023-08-13 |
mouse |
| Yilong Dong, Min Xu, Allan V Kalueff, Cai Son. Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration. European journal of nutrition. vol 57. issue 5. 2018-12-12. PMID:28523372. |
dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates bdnf function in a rodent model of neuroinflammation induced by central interleukin-1β administration. |
2018-12-12 |
2023-08-13 |
Not clear |
| Christina A E Sølvsten, Frank de Paoli, Jane H Christensen, Anders L Nielse. Voluntary Physical Exercise Induces Expression and Epigenetic Remodeling of VegfA in the Rat Hippocampus. Molecular neurobiology. vol 55. issue 1. 2018-12-11. PMID:27975171. |
in the present study, we investigated bdnf, igf-1, fgf-2, egf, and vegfa messenger rna (mrna) expression levels in the male rat hippocampus and frontal cortex after 2 weeks of voluntary physical exercise. |
2018-12-11 |
2023-08-13 |
rat |
| Christina A E Sølvsten, Frank de Paoli, Jane H Christensen, Anders L Nielse. Voluntary Physical Exercise Induces Expression and Epigenetic Remodeling of VegfA in the Rat Hippocampus. Molecular neurobiology. vol 55. issue 1. 2018-12-11. PMID:27975171. |
whereas the expression of fgf-2 was upregulated in the hippocampus and prefrontal cortex by physical exercise, the expression levels of bdnf transcript 1, bdnf transcript 4, igf-1, and vegfa were upregulated only in the hippocampus. |
2018-12-11 |
2023-08-13 |
rat |