Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yubeen Kwon, Yulan Liao, Bokyung Koo, Hojung Bae, Jiabao Zhang, Eun Hye Han, Su Min Yun, Mi Kyung Lim, Sang Ho Lee, Seo Yun Jung, Jong Hoon Ry. Ethanolic Extract of Opuntia ficus-indica var. saboten Ameliorates Cognitive Dysfunction Induced by Cholinergic Blockade in Mice. Journal of medicinal food. vol 21. issue 10. 2019-01-02. PMID:30044674. |
western blot analysis and the ex vivo study revealed that eofs increased the levels of phosphorylated extracellular signal-regulated kinase and camp response element-binding protein (creb) and the levels of brain-derived neurotrophic factor (bdnf) expression in the hippocampus. |
2019-01-02 |
2023-08-13 |
mouse |
Bombi Lee, Insop Shim, Hyejung Lee, Dae-Hyun Hah. Effects of Epigallocatechin Gallate on Behavioral and Cognitive Impairments, Hypothalamic-Pituitary-Adrenal Axis Dysfunction, and Alternations in Hippocampal BDNF Expression Under Single Prolonged Stress. Journal of medicinal food. vol 21. issue 10. 2019-01-02. PMID:30273101. |
effects of epigallocatechin gallate on behavioral and cognitive impairments, hypothalamic-pituitary-adrenal axis dysfunction, and alternations in hippocampal bdnf expression under single prolonged stress. |
2019-01-02 |
2023-08-13 |
rat |
Zhuang Miao, Fengbiao Mao, Jialong Liang, Moshe Szyf, Yan Wang, Zhong Sheng Su. Anxiety-Related Behaviours Associated with microRNA-206-3p and BDNF Expression in Pregnant Female Mice Following Psychological Social Stress. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092086. |
we employed a novel psychological stress model by introducing pregnant mice to witness the defeat process of their mated partner (wdpmp) and examined the effects of wdpmp on depression-/anxiety-like behaviours and on the expression of brain-derived neurotrophic factor (bdnf) and mir-206-3p in the hippocampus, medial prefrontal cortex (mpfc) and amygdala. |
2019-01-01 |
2023-08-13 |
mouse |
Zhuang Miao, Fengbiao Mao, Jialong Liang, Moshe Szyf, Yan Wang, Zhong Sheng Su. Anxiety-Related Behaviours Associated with microRNA-206-3p and BDNF Expression in Pregnant Female Mice Following Psychological Social Stress. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092086. |
after lactation, decreased bdnf expression in both the hippocampus and mpfc of ps mice was found to be associated with enhanced mir-206-3p levels; meanwhile, elevated bdnf associated with decreased mir-206-3p expression was evident in the amygdala of the same ps mice. |
2019-01-01 |
2023-08-13 |
mouse |
Zhuang Miao, Fengbiao Mao, Jialong Liang, Moshe Szyf, Yan Wang, Zhong Sheng Su. Anxiety-Related Behaviours Associated with microRNA-206-3p and BDNF Expression in Pregnant Female Mice Following Psychological Social Stress. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092086. |
dna methylation level in the bdnf promoter did not show difference between pc and ps mice in the hippocampus. |
2019-01-01 |
2023-08-13 |
mouse |
Zhuang Miao, Fengbiao Mao, Jialong Liang, Moshe Szyf, Yan Wang, Zhong Sheng Su. Anxiety-Related Behaviours Associated with microRNA-206-3p and BDNF Expression in Pregnant Female Mice Following Psychological Social Stress. Molecular neurobiology. vol 55. issue 2. 2019-01-01. PMID:28092086. |
these results suggest that wdpmp stress during gestation can induce long-term mood alterations in pregnant mice, which may correlate with changes in mir-206-3p and bdnf expression in the hippocampus, mpfc and amygdala. |
2019-01-01 |
2023-08-13 |
mouse |
Wei-Guan Chen, Jia-Xuan Zheng, Xi Xu, Yu-Ming Hu, Yu-Min M. Hippocampal FXR plays a role in the pathogenesis of depression: A preliminary study based on lentiviral gene modulation. Psychiatry research. vol 264. 2018-12-31. PMID:29677620. |
overexpression of hippocampal fxr induced notable depressive-like behaviors and decreased expression of brain-derived neurotrophic factor (bdnf) in naïve rats, while knockdown of hippocampal fxr fully prevented the effects of cums on rat behaviors and hippocampal bdnf expression. |
2018-12-31 |
2023-08-13 |
rat |
Simin Afshar, Siamak Shahidi, Ali Haeri Rohani, Alireza Komaki, Sara Soleimani As. The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats. Psychopharmacology. vol 235. issue 10. 2018-12-31. PMID:30027497. |
the effect of nad-299 and tcb-2 on learning and memory, hippocampal bdnf levels and amyloid plaques in streptozotocin-induced memory deficits in male rats. |
2018-12-31 |
2023-08-13 |
rat |
Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
within the hippocampus, mediators of neural plasticity such as brain-derived neurotrophic factor (bdnf), can influence and be influenced by cort, hippocampus-associated behaviors and regulatory epigenetic modification enzymes. |
2018-12-31 |
2023-08-13 |
Not clear |
Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
here, we investigated whether individuals and populations colonizing a new geographic range, senegal, vary in the expression of bdnf and dna methyltransferases (dnmts) within the hippocampus and the release of cort in response to a stressor. |
2018-12-31 |
2023-08-13 |
Not clear |
Holly J Kilvitis, Daniel R Ardia, Massamba Thiam, Lynn B Marti. Corticosterone is correlated to mediators of neural plasticity and epigenetic potential in the hippocampus of Senegalese house sparrows (Passer domesticus). General and comparative endocrinology. vol 269. 2018-12-31. PMID:30257180. |
we surveyed three populations across senegal, predicting that hippocampal bdnf and dnmt expression would be highest at the range-edge, and that bdnf and dnmt would be inversely related to one another, but would each positively covary with cort within individuals. |
2018-12-31 |
2023-08-13 |
Not clear |
J-L Rault, A J Lawrence, C R Ralp. Brain-derived neurotrophic factor in serum as an animal welfare indicator of environmental enrichment in pigs. Domestic animal endocrinology. vol 65. 2018-12-27. PMID:30007130. |
higher bdnf concentration is ultimately linked to higher stress resilience, and bdnf in the hippocampus enhances learning and memory. |
2018-12-27 |
2023-08-13 |
Not clear |
Timothy M Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A Baccarelli, Liqiong Gu. The effect of morphine upon DNA methylation in ten regions of the rat brain. Epigenetics. vol 12. issue 12. 2018-12-21. PMID:29111854. |
we observed differential methylation of bdnf and il6 in the pons, nr3c1 in the cerebellum, and il1b in the hippocampus in response to acute morphine exposure (all p value < 0.05). |
2018-12-21 |
2023-08-13 |
rat |
Timothy M Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A Baccarelli, Liqiong Gu. The effect of morphine upon DNA methylation in ten regions of the rat brain. Epigenetics. vol 12. issue 12. 2018-12-21. PMID:29111854. |
chronic exposure was associated with differential methylation of bdnf and comt in the pons, nr3c1 in the hippocampus and il1b in the medulla oblongata (all p value < 0.05). |
2018-12-21 |
2023-08-13 |
rat |
Kenichi Kawahori, Koshi Hashimoto, Xunmei Yuan, Kazutaka Tsujimoto, Nozomi Hanzawa, Miho Hamaguchi, Saori Kase, Kyota Fujita, Kazuhiko Tagawa, Hitoshi Okazawa, Yasuyo Nakajima, Nobuyuki Shibusawa, Masanobu Yamada, Yoshihiro Ogaw. Mild Maternal Hypothyroxinemia During Pregnancy Induces Persistent DNA Hypermethylation in the Hippocampal Brain-Derived Neurotrophic Factor Gene in Mouse Offspring. Thyroid : official journal of the American Thyroid Association. vol 28. issue 3. 2018-12-21. PMID:29415629. |
this may be due to the persistent reduced expression of the hippocampal brain-derived neurotrophic factor gene bdnf, which plays a crucial role in cns development. |
2018-12-21 |
2023-08-13 |
mouse |
Weike Chen, Tingting Liang, Wenwen Zuo, Xin Wu, Zibo Shen, Fang Wang, Cunyu Li, Yunfeng Zheng, Guoping Pen. Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 106. 2018-12-18. PMID:29957471. |
compared to senescence-accelerated-resistant mouse 1 (samr1) mice, samp8 mice exhibited conspicuous declines in spatial memory abilities and brain-derived neurotrophic factor (bdnf) and tyrosine kinase receptors (trkb) level in hippocampus; increased aβ deposition, β-secretase (bace1) level, microglia activation and inflammatory factors, including interleukin-1β (il-1β), interleukin-6 (il-6) and tumor necrosis factor α (tnf-α) in the brain. |
2018-12-18 |
2023-08-13 |
mouse |
Tengfei Zhao, Yingxue Fu, Hao Sun, Xiaoquan Li. Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia. IUBMB life. vol 70. issue 1. 2018-12-17. PMID:29247598. |
at the end of the experiments, the hippocampal biomarkers brain-derived neurotrophic factor (bdnf), monocyte chemotactic protein 1 (mcp-1), and homocysteine (hcy) were examined. |
2018-12-17 |
2023-08-13 |
rat |
Fernanda Nunes, Daniela Pochmann, Amanda Staldoni Almeida, Daniela Melo Marques, Lisiane de Oliveira Porciúncul. Differential Behavioral and Biochemical Responses to Caffeine in Male and Female Rats from a Validated Model of Attention Deficit and Hyperactivity Disorder. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29557061. |
shr rats from both sexes presented increases in the bdnf, truncated and phospho-trkb receptors and also phospho-creb levels in the hippocampus. |
2018-12-17 |
2023-08-13 |
rat |
Fernanda Nunes, Daniela Pochmann, Amanda Staldoni Almeida, Daniela Melo Marques, Lisiane de Oliveira Porciúncul. Differential Behavioral and Biochemical Responses to Caffeine in Male and Female Rats from a Validated Model of Attention Deficit and Hyperactivity Disorder. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29557061. |
besides, our data revealed that caffeine intake since childhood attenuated behavioral alterations in the adhd model associated with changes in bdnf and trkb receptors in the hippocampus. |
2018-12-17 |
2023-08-13 |
rat |
Willy Chou, Yu-Fan Liu, Cheng-Hsien Lin, Mao-Tsun Lin, Chi-Chun Chen, Wen-Pin Liu, Ching-Ping Chang, Chung-Ching Chi. Exercise Rehabilitation Attenuates Cognitive Deficits in Rats with Traumatic Brain Injury by Stimulating the Cerebral HSP20/BDNF/TrkB Signalling Axis. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29574629. |
in addition to increasing hippocampal and cortical expression of hsp20, brain-derived neurotrophic factor (bdnf), and the tropomyosin receptor kinase b (trkb) ratio, pe rehabilitation significantly attenuated brain contusion and improved cognitive deficits in the rat model. |
2018-12-17 |
2023-08-13 |
rat |