Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
these behavioural changes were associated with increased aβ depositions and lowered bdnf levels in brain hippocampal homogenates. |
2019-03-21 |
2023-08-13 |
rat |
Harikesh Dubey, Kavita Gulati, Arunabha Ra. Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats. Neurotoxicology. vol 66. 2019-03-21. PMID:29522778. |
the icv-stz induced elevations in aβ40 and aβ42 and reduced levels of bdnf in hippocampal homogenates were also attenuated after gsno treatment in these rats. |
2019-03-21 |
2023-08-13 |
rat |
Wataru Ito, Howard Huang, Vanessa Brayman, Alexei Morozo. Impaired social contacts with familiar anesthetized conspecific in CA3-restricted brain-derived neurotrophic factor knockout mice. Genes, brain, and behavior. vol 18. issue 1. 2019-03-21. PMID:30120813. |
we then applied this test to highly aggressive mice with a hippocampal ca3-restricted knockout (ko) of brain-derived neurotrophic factor (bdnf), in which aggression may mask other social behaviors. |
2019-03-21 |
2023-08-13 |
mouse |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal glucocorticoid receptor dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
moreover, apelin-13 ameliorated hypothalamic-pituitary-adrenal (hpa) axis hyperactivity, and hippocampal bdnf expression deficit and glucocorticoid receptor (gr) nucleus translocation hypoactivity in chronic stressed rats. |
2019-03-21 |
2023-08-13 |
rat |
Ting-Ting Dai, Bo Wang, Zhi-Yong Xiao, Yong You, Shao-Wen Tia. Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions. Neuroscience. vol 390. 2019-03-21. PMID:30170158. |
these results suggest that apelin-13 upregulates bdnf against chronic stress-induced depression-like phenotypes by ameliorating hpa axis and hippocampal gr dysfunctions. |
2019-03-21 |
2023-08-13 |
rat |
Bo Ren, Tian Yuan, Zhijun Diao, Chenxi Zhang, Zhigang Liu, Xuebo Li. Protective effects of sesamol on systemic oxidative stress-induced cognitive impairments via regulation of Nrf2/Keap1 pathway. Food & function. vol 9. issue 11. 2019-03-20. PMID:30375618. |
meanwhile, sesamol ameliorated neuronal damage and improved bdnf level in rat hippocampus. |
2019-03-20 |
2023-08-13 |
mouse |
Kamilla Blecharz-Klin, Adriana Wawer, Katarzyna Jawna-Zboińska, Justyna Pyrzanowska, Agnieszka Piechal, Dagmara Mirowska-Guzel, Ewa Widy-Tyszkiewic. Early paracetamol exposure decreases brain-derived neurotrophic factor (BDNF) in striatum and affects social behaviour and exploration in rats. Pharmacology, biochemistry, and behavior. vol 168. 2019-03-15. PMID:29545027. |
quantification of brain-derived neurotrophic factor (bdnf) was determined in prefrontal cortex, hippocampus and striatum using enzyme-linked immunosorbent assay (elisa). |
2019-03-15 |
2023-08-13 |
rat |
Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
the bdnf/trkb immunohistochemical expression in the hippocampus was measured and serum bdnf was determined. |
2019-03-15 |
2023-08-13 |
rat |
Michaela Shishmanova-Doseva, Lyudmil Peychev, Yvetta Koeva, Dora Terzieva, Katerina Georgieva, Zhivko Peyche. Chronic treatment with the new anticonvulsant drug lacosamide impairs learning and memory processes in rats: A possible role of BDNF/TrkB ligand receptor system. Pharmacology, biochemistry, and behavior. vol 169. 2019-03-15. PMID:29605232. |
lacosamide induced a dose-dependent reduction of the hippocampal expression of bdnf and its receptor trkb. |
2019-03-15 |
2023-08-13 |
rat |
G Aleph Prieto, Liqi Tong, Erica D Smith, Carl W Cotma. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemical research. vol 44. issue 1. 2019-03-14. PMID:29619614. |
we also found that il-18 does not impair cltp or brain-derived neurotrophic factor (bdnf) signaling in primary hippocampal neuronal cultures. |
2019-03-14 |
2023-08-13 |
mouse |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
changes in oxidative stress biomarkers, brain derived neuroptrophic factor (bdnf), and epigenetics (histones) in the hippocampus following treatments were measured using enzymatic assays. |
2019-03-12 |
2023-08-13 |
rat |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
furthermore, ptx normalized sps induced changes in the hippocampus gsh/gssg ratio, activity of catalase, and glutathione peroxidase (gpx), bdnf, and certain histones levels. |
2019-03-12 |
2023-08-13 |
rat |
Karem H Alzoubi, Omar F Khabour, Mohammed Ahme. Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. Brain research bulletin. vol 139. 2019-03-12. PMID:29559394. |
in conclusion, the sps model of ptsd-like behavior induced memory impairment, whereas ptx prevented this impairment possibly through normalizing antioxidant mechanisms, bdnf and epigenetic changes in the hippocampus. |
2019-03-12 |
2023-08-13 |
rat |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
beta-hydroxybutyrate promotes the expression of bdnf in hippocampal neurons under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
here we demonstrated that bhba administration induced the expression of bdnf in the hippocampus of mice fed with normal diet. |
2019-03-11 |
2023-08-13 |
mouse |
Erling Hu, Huan Du, Xinliang Zhu, Leilei Wang, Sen Shang, Xingjuan Wu, Haixia Lu, Xiaoyun L. Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply. Neuroscience. vol 386. 2019-03-11. PMID:29966721. |
in vitro experiment results also showed that 0.02-2 mm bhba significantly increased bdnf expression in both the primary hippocampal neurons and the hippocampus neuron cell line ht22 under adequate glucose supply. |
2019-03-11 |
2023-08-13 |
mouse |
Marwa M Nagib, Mariane G Tadros, Rania M Rahmo, Nagwa Ali Sabri, Amani E Khalifa, Somaia I Masou. Ameliorative Effects of α-Tocopherol and/or Coenzyme Q10 on Phenytoin-Induced Cognitive Impairment in Rats: Role of VEGF and BDNF-TrkB-CREB Pathway. Neurotoxicity research. vol 35. issue 2. 2019-03-11. PMID:30374909. |
moreover, vegf, bdnf, trkb, and creb gene expression levels in the hippocampus and prefrontal cortex were estimated using rt-pcr. |
2019-03-11 |
2023-08-13 |
rat |
Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
in the hippocampus of female offspring, bpa exposure resulted in hypermethylation of the putative 5' promoter region of bdnf, while ee exposure induced hypomethylation. |
2019-03-08 |
2023-08-13 |
rat |
Ana Cheong, Sarah A Johnson, Emily C Howald, Mark R Ellersieck, Luísa Camacho, Sherry M Lewis, Michelle M Vanlandingham, Jun Ying, Shuk-Mei Ho, Cheryl S Rosenfel. Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study. Epigenetics. vol 13. issue 7. 2019-03-08. PMID:30001178. |
hippocampal bdnf expression in females showed a weak negative association with sniffing correct hole in barnes maze. |
2019-03-08 |
2023-08-13 |
rat |