| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincent Martin, Najib Allaïli, Marine Euvrard, Tevrasamy Marday, Armance Riffaud, Bernard Franc, Elisabeth Mocaër, Cecilia Gabriel, Philippe Fossati, Stéphane Lehericy, Laurence Lanfume. Effect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice. Scientific reports. vol 8. 2018-12-11. PMID:28374847. |
in this context, we investigated the effects of chronic social defeat stress (csds) on anxiety-, social- and cognitive-related behaviors, as well as hippocampal bdnf, synaptic plasticity markers (psd-95, synaptophysin, spinophilin, synapsin i and map-2), and epigenetic modifying enzymes (myst2, hdac2, hdac6, mll3, kdm5b, dnmt3b, gadd45b) gene expression in c57bl/6j mice. |
2018-12-11 |
2023-08-13 |
mouse |
| Vincent Martin, Najib Allaïli, Marine Euvrard, Tevrasamy Marday, Armance Riffaud, Bernard Franc, Elisabeth Mocaër, Cecilia Gabriel, Philippe Fossati, Stéphane Lehericy, Laurence Lanfume. Effect of agomelatine on memory deficits and hippocampal gene expression induced by chronic social defeat stress in mice. Scientific reports. vol 8. 2018-12-11. PMID:28374847. |
while total bdnf mrna level was unchanged, bdnf exon iv, map-2, hdac2, hdac6 and mll3 gene expression was significantly decreased in the csds mouse hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Yue Zhu, Cheng Chao, Xiuzhu Duan, Xiaoxuan Cheng, Pei Liu, Shulan Su, Jinao Duan, Tina Tingxia Dong, Karl Wah-Keung Tsi. Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus. Scientific reports. vol 7. issue 1. 2018-12-11. PMID:28469194. |
kxs might fulfill this effect by up-regulating the expressions of ngf, bdnf and trk receptors in hippocampus, which were confirmed by the treatment of corresponding blockers tpa-stop and k252a. |
2018-12-11 |
2023-08-13 |
mouse |
| RamaRao Golime, Meehir Palit, J Acharya, D K Dube. Neuroprotective Effects of Galantamine on Nerve Agent-Induced Neuroglial and Biochemical Changes. Neurotoxicity research. vol 33. issue 4. 2018-12-11. PMID:28929435. |
mrna expression studies using quantitative real-time pcr revealed significant changes in s-100β, gfap, c-fos, and bdnf in the hippocampus and piriform cortex after soman (90 μg/kg, s.c) exposure. |
2018-12-11 |
2023-08-13 |
rat |
| b' Hagit Cohen, Ella Vainer, Kaplan Zeev, Joseph Zohar, Aleksander A Math\\xc3\\xa. Neuropeptide S in the basolateral amygdala mediates an adaptive behavioral stress response in a rat model of posttraumatic stress disorder by increasing the expression of BDNF and the neuropeptide YY1 receptor. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 1. 2018-12-11. PMID:29157796.' |
to elucidate the molecular mechanism by which nps attenuates behavioral stress responses, expression levels of neuropeptide y (npy), npy-y1 receptor (npy-y1r), and brain-derived neurotrophic factor (bdnf) were evaluated in the hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Xi Chen, Xue Zhou, Lu Yang, Xu Miao, Di-Han Lu, Xiao-Yu Yang, Zhi-Bin Zhou, Wen-Bin Kang, Ke-Yu Chen, Li-Hua Zhou, Xia Fen. Neonatal Exposure to Low-Dose (1.2%) Sevoflurane Increases Rats' Hippocampal Neurogenesis and Synaptic Plasticity in Later Life. Neurotoxicity research. vol 34. issue 2. 2018-12-11. PMID:29427282. |
the expression levels of bdnf, trkb, postsynaptic density (psd)-95, and synaptophysin in the hippocampus were also increased in the 1.2% sevo group. |
2018-12-11 |
2023-08-13 |
rat |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
bdnf effects on dendritic spine morphology and hippocampal function. |
2018-12-11 |
2023-08-13 |
Not clear |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
neurotrophins, including brain-derived neurotrophic factor (bdnf), are expressed in the hippocampus, as well as their precursors, the pro-neurotrophins. |
2018-12-11 |
2023-08-13 |
Not clear |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
this points to a role of bdnf as a central regulator of neuronal plasticity within the postnatal hippocampus. |
2018-12-11 |
2023-08-13 |
Not clear |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
the possible roles of bdnf in neuronal plasticity within the hippocampus are highlighted in this review by focusing on the morphological components of neuronal plasticity. |
2018-12-11 |
2023-08-13 |
Not clear |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
moreover, we also found that cort levels in serum were significantly increased, along with the decrease of brain-derived neurotrophic factor (bdnf) mrna, bdnf protein, 5-hydroxytryptamine (5-ht) and norepinephrine (ne) levels in the hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
these findings indicated that magnolol possessed antidepressant effects in mice exposed to cort, which might be partially related to modulate hpa axis, up-regulate bdnf expression and increase neurotransmitters levels in the hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Mi Kyoung Seo, Young Hoon Kim, Roger S McIntyre, Rodrigo B Mansur, Yena Lee, Nicole E Carmona, Ah Jeong Choi, Gyung-Mee Kim, Jung Goo Lee, Sung Woo Par. Effects of Antipsychotic Drugs on the Epigenetic Modification of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampi of Chronic Restraint Stress Rats. Neural plasticity. vol 2018. 2018-12-11. PMID:29991943. |
therefore, we investigated the effects of antipsychotic drugs on the epigenetic modification of the bdnf gene in the rat hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Mi Kyoung Seo, Young Hoon Kim, Roger S McIntyre, Rodrigo B Mansur, Yena Lee, Nicole E Carmona, Ah Jeong Choi, Gyung-Mee Kim, Jung Goo Lee, Sung Woo Par. Effects of Antipsychotic Drugs on the Epigenetic Modification of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampi of Chronic Restraint Stress Rats. Neural plasticity. vol 2018. 2018-12-11. PMID:29991943. |
these findings suggest that the antipsychotic drug olanzapine induced histone modification of bdnf gene expression in the hippocampus and that these epigenetic alterations may represent one of the mechanisms underlying the actions of antipsychotic drugs. |
2018-12-11 |
2023-08-13 |
rat |
| R Rahimi, M M Akhavan, K Kamyab, S A Ebrahim. Maternal voluntary exercise ameliorates learning deficit in rat pups exposed, in utero, to valproic acid; role of BDNF and VEGF and their receptors. Neuropeptides. vol 71. 2018-12-11. PMID:30144942. |
furthermore, the alteration of hippocampal brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf) and their respective receptors were measured. |
2018-12-11 |
2023-08-13 |
rat |
| R Rahimi, M M Akhavan, K Kamyab, S A Ebrahim. Maternal voluntary exercise ameliorates learning deficit in rat pups exposed, in utero, to valproic acid; role of BDNF and VEGF and their receptors. Neuropeptides. vol 71. 2018-12-11. PMID:30144942. |
also, on pnd 30, hippocampal bdnf and vegf were measured by elisa and western blot analysis respectively. |
2018-12-11 |
2023-08-13 |
rat |
| R Rahimi, M M Akhavan, K Kamyab, S A Ebrahim. Maternal voluntary exercise ameliorates learning deficit in rat pups exposed, in utero, to valproic acid; role of BDNF and VEGF and their receptors. Neuropeptides. vol 71. 2018-12-11. PMID:30144942. |
voluntary exercise and to a much greater extent vpa administration increased hippocampal bdnf. |
2018-12-11 |
2023-08-13 |
rat |
| Gokul Krishna, Rahul Agrawal, Yumei Zhuang, Zhe Ying, Afshin Paydar, Neil G Harris, Luiz Fernando F Royes, Fernando Gomez-Pinill. 7,8-Dihydroxyflavone facilitates the action exercise to restore plasticity and functionality: Implications for early brain trauma recovery. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 6. 2018-11-27. PMID:28315455. |
compared to sham-injured controls, tbi resulted in reduced hippocampal activation of the bdnf receptor trkb and associated creb, reduced levels of plasticity markers gap-43 and syn i, as well as impaired memory as indicated by the barnes maze task. |
2018-11-27 |
2023-08-13 |
Not clear |
| Ming Cui, Huiwen Xiao, Yuan Li, Jiali Dong, Dan Luo, Hang Li, Guoxing Feng, Haichao Wang, Saijun Fa. Total abdominal irradiation exposure impairs cognitive function involving miR-34a-5p/BDNF axis. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 9. 2018-11-27. PMID:28668331. |
mechanically, microarray assay analysis revealed that tai elevated the expression level of mir-34a-5p in small intestine tissues and peripheral blood (pd), which targeted the 3'utr of brain-derived neurotrophic factor (bdnf) mrna in hippocampus to mediate cognitive dysfunction. |
2018-11-27 |
2023-08-13 |
mouse |
| Ming Cui, Huiwen Xiao, Yuan Li, Jiali Dong, Dan Luo, Hang Li, Guoxing Feng, Haichao Wang, Saijun Fa. Total abdominal irradiation exposure impairs cognitive function involving miR-34a-5p/BDNF axis. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 9. 2018-11-27. PMID:28668331. |
tail intravenous injection of mir-34a-5p antagomir immediately after tai exposure rescued tai-mediated cognitive impairment via blocking the up-regulation of mir-34a-5p in pd, resulting in restoring the bdnf expression in the hippocampus. |
2018-11-27 |
2023-08-13 |
mouse |