| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mojtaba Salehpour, Fariba Khodagholi, Arman Zeinaddini Meymand, Maryam Nourshahi, Ghorbangol Ashab. Exercise training with concomitant nitric oxide synthase inhibition improved anxiogenic behavior, spatial cognition, and BDNF/P70S6 kinase activation in 20-month-old rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 43. issue 1. 2018-09-18. PMID:28854337. |
bdnf, p70s6k, and cleaved caspase-3 protein levels in the hippocampus and prefrontal cortex were evaluated by western blotting. |
2018-09-18 |
2023-08-13 |
rat |
| Mojtaba Salehpour, Fariba Khodagholi, Arman Zeinaddini Meymand, Maryam Nourshahi, Ghorbangol Ashab. Exercise training with concomitant nitric oxide synthase inhibition improved anxiogenic behavior, spatial cognition, and BDNF/P70S6 kinase activation in 20-month-old rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 43. issue 1. 2018-09-18. PMID:28854337. |
exercise and treatment with a low dose of l-name (25 mg/kg) each increased bdnf and p70s6k in the hippocampus and prefrontal cortex compared with levels in control rats. |
2018-09-18 |
2023-08-13 |
rat |
| Mojtaba Salehpour, Fariba Khodagholi, Arman Zeinaddini Meymand, Maryam Nourshahi, Ghorbangol Ashab. Exercise training with concomitant nitric oxide synthase inhibition improved anxiogenic behavior, spatial cognition, and BDNF/P70S6 kinase activation in 20-month-old rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 43. issue 1. 2018-09-18. PMID:28854337. |
in comparison with exercise alone, co-treatment with exercise and a low dose of l-name (25 mg/kg) also increased bdnf and p70s6k in the hippocampus. |
2018-09-18 |
2023-08-13 |
rat |
| Sung Woo Park, Mi Kyoung Seo, Jung Goo Lee, Le Thi Hien, Young Hoon Ki. Effects of maternal separation and antidepressant drug on epigenetic regulation of the brain-derived neurotrophic factor exon I promoter in the adult rat hippocampus. Psychiatry and clinical neurosciences. vol 72. issue 4. 2018-09-13. PMID:28990703. |
we investigated epigenetic changes at the bdnf exon i promoter in the hippocampus of adult rats subjected to maternal separation (ms) during early life and treated with an antidepressant drug as adults. |
2018-09-13 |
2023-08-13 |
rat |
| Shuai Lian, Di Wang, Bin Xu, Wenjin Guo, Lipeng Wang, Wenjie Li, Hong Ji, Jianfa Wang, Fanzhi Kong, Li Zhen, Shize Li, Liping Zhang, Jingru Guo, Huanmin Yan. Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behavioural brain research. vol 346. 2018-09-11. PMID:29421306. |
cold stress reduced the bdnf level in the maternal hippocampus in contrast to the increase in rbm3. |
2018-09-11 |
2023-08-13 |
rat |
| Yong-Hyun Ko, Sun Yeou Kim, Seok-Yong Lee, Choon-Gon Jan. 6,7,4'-Trihydroxyisoflavone, a major metabolite of daidzein, improves learning and memory via the cholinergic system and the p-CREB/BDNF signaling pathway in mice. European journal of pharmacology. vol 826. 2018-09-10. PMID:29510125. |
in addition, immunohistochemistry and western blot results revealed that 6,7,4'-thif significantly increased brain-derived neurotrophic factor (bdnf) and phosphor camp response element binding (creb) in the hippocampus of mice. |
2018-09-10 |
2023-08-13 |
mouse |
| Εvgenia Dandi, Aikaterini Kalamari, Olga Touloumi, Rosa Lagoudaki, Evangelia Nousiopoulou, Constantina Simeonidou, Evangelia Spandou, Despina A Tat. Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 67. 2018-09-10. PMID:29545098. |
after completion of behavioral testing, blood samples were taken for evaluation of stress-induced plasma corticosterone using an enzyme-linked immunosorbent assay (elisa), while immunofluorescence was applied to evaluate hippocampal bdnf and synaptophysin expression in dorsal hippocampus. |
2018-09-10 |
2023-08-13 |
rat |
| Εvgenia Dandi, Aikaterini Kalamari, Olga Touloumi, Rosa Lagoudaki, Evangelia Nousiopoulou, Constantina Simeonidou, Evangelia Spandou, Despina A Tat. Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 67. 2018-09-10. PMID:29545098. |
these changes were associated with increased bdnf and synaptophysin expression in the hippocampus. |
2018-09-10 |
2023-08-13 |
rat |
| J P Hayes, A Reagan, M W Logue, S M Hayes, N Sadeh, D R Miller, M Verfaellie, E J Wolf, R E McGlinchey, W P Milberg, A Stone, S A Schichman, M W Mille. BDNF genotype is associated with hippocampal volume in mild traumatic brain injury. Genes, brain, and behavior. vol 17. issue 2. 2018-08-30. PMID:28755387. |
bdnf genotype is associated with hippocampal volume in mild traumatic brain injury. |
2018-08-30 |
2023-08-13 |
human |
| J P Hayes, A Reagan, M W Logue, S M Hayes, N Sadeh, D R Miller, M Verfaellie, E J Wolf, R E McGlinchey, W P Milberg, A Stone, S A Schichman, M W Mille. BDNF genotype is associated with hippocampal volume in mild traumatic brain injury. Genes, brain, and behavior. vol 17. issue 2. 2018-08-30. PMID:28755387. |
results showed that the bdnf snp rs1157659 interacted with mtbi to predict hippocampal volume. |
2018-08-30 |
2023-08-13 |
human |
| Gaofeng Sheng, Jinlin Zhang, Shengfeng Gao, Yuanyuan Gu, Bo Jiang, Qiufang Ga. SKF83959 Has Protective Effects in the Scopolamine Model of Dementia. Biological & pharmaceutical bulletin. vol 41. issue 3. 2018-08-29. PMID:29491219. |
moreover, skf83959 treatment significantly antagonized the down-regulating effects of scopolamine on brain-derived neurotrophic factor (bdnf) signaling cascade in the hippocampus, but not cortex. |
2018-08-29 |
2023-08-13 |
Not clear |
| Gaofeng Sheng, Jinlin Zhang, Shengfeng Gao, Yuanyuan Gu, Bo Jiang, Qiufang Ga. SKF83959 Has Protective Effects in the Scopolamine Model of Dementia. Biological & pharmaceutical bulletin. vol 41. issue 3. 2018-08-29. PMID:29491219. |
collectively, this study shows that skf83959 has beneficial effects in the scopolamine model of dementia by modulation of hippocampal bdnf signaling, implying a novel and potential therapeutic agent for treating dementia in ad. |
2018-08-29 |
2023-08-13 |
Not clear |
| Kun Li, Si Shen, Yu-Tian Ji, Xu-Yun Li, Li-San Zhang, Xiao-Dong Wan. Melatonin Augments the Effects of Fluoxetine on Depression-Like Behavior and Hippocampal BDNF-TrkB Signaling. Neuroscience bulletin. vol 34. issue 2. 2018-08-28. PMID:29086908. |
moreover, we found that the antidepressant effects of combined treatment were associated with the normalization of brain-derived neurotrophic factor (bdnf)-tropomyosin receptor kinase b (trkb) signaling in the hippocampus, but not in the prefrontal cortex. |
2018-08-28 |
2023-08-13 |
mouse |
| John Marshall, Xiao-Zhong Zhou, Gang Chen, Su-Qing Yang, Ya Li, Yin Wang, Zhi-Qing Zhang, Qin Jiang, Lutz Birnbaumer, Cong Ca. Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 15. 2018-08-24. PMID:29507199. |
antidepression action of bdnf requires and is mimicked by gαi1/3 expression in the hippocampus. |
2018-08-24 |
2023-08-13 |
mouse |
| Sahreh Shabani, Yaghoob Farbood, Seyyed Ali Mard, Alireza Sarkaki, Akram Ahangarpour, Layasadat Khorsand. The regulation of pituitary-thyroid abnormalities by peripheral administration of levothyroxine increased brain-derived neurotrophic factor and reelin protein expression in an animal model of Alzheimer's disease. Canadian journal of physiology and pharmacology. vol 96. issue 3. 2018-08-20. PMID:28846851. |
alzheimer's disease (ad) is associated with decreased serum levels of thyroid hormones (ths), increased levels of thyroid-stimulating hormone (tsh), and decreased protein expression of brain-derived neurotrophic factor (bdnf) and reelin in the hippocampus. |
2018-08-20 |
2023-08-13 |
Not clear |
| Ayano Shimizu, Takakazu Mitani, Sachi Tanaka, Hiroshi Fujii, Motohiro Maebuchi, Yusuke Amiya, Mitsuru Tanaka, Toshiro Matsui, Soichiro Nakamura, Shigeru Katayam. Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain. Journal of agricultural and food chemistry. vol 66. issue 30. 2018-08-14. PMID:29985005. |
furthermore, its administration in vivo increased the expression of bdnf in the cerebral cortex and the number of neurons in hippocampus and cerebral cortex. |
2018-08-14 |
2023-08-13 |
mouse |
| G T Shishkina, D A Lanshakov, A V Bannova, T S Kalinina, N P Agarina, N N Dygal. Doxycycline Used for Control of Transgene Expression has its Own Effects on Behaviors and Bcl-xL in the Rat Hippocampus. Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:28861774. |
in addition, the levels of mrnas and proteins of brain-derived neurotrophic factor (bdnf) and anti-apoptotic protein bcl-xl in the hippocampus (hipp) and frontal cortex (fc) were also analyzed. |
2018-08-13 |
2023-08-13 |
rat |
| Karine Mathilde Campestrini Dallagnol, Aline Pertile Remor, Rodrigo Augusto da Silva, Rui Daniel Prediger, Alexandra Latini, Aderbal Silva Aguia. Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice. Brain, behavior, and immunity. vol 61. 2018-08-10. PMID:27477921. |
we evaluate the effect of 8weeks of physical activity on running wheels (rw) on motor and depressive-like behavior and hippocampal gene expression of brain-derived neurotrophic factor (bdnf), rest, and interleukins il-1β and il-10 of adult and aged c57bl/6 mice. |
2018-08-10 |
2023-08-13 |
mouse |
| Karine Mathilde Campestrini Dallagnol, Aline Pertile Remor, Rodrigo Augusto da Silva, Rui Daniel Prediger, Alexandra Latini, Aderbal Silva Aguia. Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice. Brain, behavior, and immunity. vol 61. 2018-08-10. PMID:27477921. |
physical activity also boosted bdnf and rest expression and decreased il-1β and il-10 expression in the hippocampus of aged animals. |
2018-08-10 |
2023-08-13 |
mouse |
| Majid Motaghinejad, Manijeh Motevalian, Sulail Fatima, Fahimeh Faraji, Shiva Mozaffar. The Neuroprotective Effect of Curcumin Against Nicotine-Induced Neurotoxicity is Mediated by CREB-BDNF Signaling Pathway. Neurochemical research. vol 42. issue 10. 2018-08-07. PMID:28608236. |
in addition, nicotine treatment increased lipid peroxidation and the levels of gsh, il-1β, tnf-α and bax, while reducing bcl-2, p-creb and bdnf levels in the hippocampus. |
2018-08-07 |
2023-08-13 |
rat |