| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John S. Rudge, Ralph F. Alderson, Elizabeth Pasnikowski, Joyce McClain, Nancy Y. Ip, Ronald M. Lindsa. Expression of Ciliary Neurotrophic Factor and the Neurotrophins-Nerve Growth Factor, Brain-Derived Neurotrophic Factor and Neurotrophin 3-in Cultured Rat Hippocampal Astrocytes. The European journal of neuroscience. vol 4. issue 6. 2019-11-20. PMID:12106332. |
in order to examine which factors may be responsible for these activities, we have examined the expression of the genes for four known neurotrophic factors-ciliary neurotrophic factor (cntf), nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin 3 (nt3)-in purified astrocyte cultures derived from neonatal rat hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
exercise has been found to increase bdnf mrna levels in various brain regions, including specific subpopulations of hippocampal neurons. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
expression of bdnf mrna in the hippocampus was assessed with in situ hybridization and densitometry. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
hybridization signal for bdnf mrna was significantly increased bilaterally in the exercise group in hippocampal regions ca1 and ca3 (p<0.05), but not in the granule cell layer of the dentate gyrus. |
2019-11-20 |
2023-08-12 |
rat |
| Ramona R. Hicks, Arden Boggs, Denise Leider, Philip Kraemer, Russell Brown, Stephen W. Scheff, Kim B. Seroog. Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats. Restorative neurology and neuroscience. vol 12. issue 1. 2019-11-20. PMID:12671319. |
this study suggests that after traumatic brain injury, exercise elevates bdnf mrna in specific regions of the hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Xuan Liu, Junjian Zhang, Dong Sun, Yuanteng Fan, Hongbin Zhou, Binfang F. Fluoxetine enhances Brain Derived Neurotropic Factor Serum Concentration and Cognition in Patients with Vascular Dementia. Current neurovascular research. 2019-11-20. PMID:23962390. |
selective serotonin reuptake inhibitors (ssris) improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (bdnf) in the rat hippocampus. |
2019-11-20 |
2023-08-12 |
rat |
| Damian G Maur, Cecilia G Pascuan, Ana M Genaro, Maria A Zorrilla-Zubilet. Involvement of Nitric Oxide, Neurotrophins and HPA Axis in Neurobehavioural Alterations Induced by Prenatal Stress. Advances in neurobiology. vol 10. 2019-11-20. PMID:25287536. |
thus, it has been found that the neuronal isoform of nitric oxide synthase (nnos) is an endogenous inhibitor of glucocorticoid receptor (gr) in the hippocampus and that nnos in the hippocampus may participate in the modulation of hypothalamic-pituitary-adrenal axis activity via gr.neurotrophins are a family of secreted growth factors consisting of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt3) and nt4. |
2019-11-20 |
2023-08-13 |
Not clear |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
transplantation to the anterior chamber of the eye increased the expression of bdnf in the hippocampal but not the brain stem tissue, compared with levels observed in fetal and adult rats in vivo. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
in addition, double grafting with hippocampal tissue more than tripled bdnf levels in brain stem grafts and doubled bdnf levels in the hippocampal portion of double grafts compared with hippocampal single grafts. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
triple grafts containing basal forebrain, hippocampus, and brain stem lc tissue increased brain stem and hippocampal bdnf levels even further. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
colchicine treatment of lc-hippocampal double grafts gave rise to a significant decrease in hippocampal bdnf levels to levels seen in single hippocampal grafts, while only a partial reduction of bdnf levels was seen in the brain stem portion of the same double grafts treated with colchicine. |
2019-11-20 |
2023-08-13 |
rat |
| L Willis, E M Quintero, M Nelson, A-Ch Granhol. Regulation of Trophic Factor Expression by Innervating Target Regions in Intraocular Double Transplants. Cell transplantation. vol 14. issue 1. 2019-11-20. PMID:28863735. |
the findings suggest that an appropriate hippocampal innervation or contact with its target tissues is essential for regulation of bdnf expression in the brain stem, and that retrograde transport of bdnf can occur between double grafted fetal tissues in oculo. |
2019-11-20 |
2023-08-13 |
rat |
| Mu-Huo Ji, Hui Tang, Dan Luo, Li-Li Qiu, Min Jia, Hong-Mei Yuan, Shan-Wu Feng, Jian-Jun Yan. Environmental conditions differentially affect neurobehavioral outcomes in a mouse model of sepsis-associated encephalopathy. Oncotarget. vol 8. issue 47. 2019-11-20. PMID:29137271. |
the expressions of proinflammatory cytokines (tumor necrosis factor (tnf-α), interleukin-1β (il-1β), il-6, il-10), ionized calcium-binding adaptor molecule-1 (iba1)-positive cells as well as glial fibrillary acidic protein (gfap)-positive cells, brain derived neurotrophic factor (bdnf), 5-bromo-2-deoxyuridine-labeled cells in the dentate gyrus of the hippocampus, and the number of dendritic spines in the hippocampal ca1 were determined. |
2019-11-20 |
2023-08-13 |
mouse |
| Shih-Wen Li, Hong-Ren Yu, Jiunn-Ming Sheen, Mao-Meng Tiao, You-Lin Tain, I-Chun Lin, Yu-Ju Lin, Kow-Aung Chang, Ching-Chou Tsai, Li-Tung Huan. A maternal high-fat diet during pregnancy and lactation, in addition to a postnatal high-fat diet, leads to metabolic syndrome with spatial learning and memory deficits: beneficial effects of resveratrol. Oncotarget. vol 8. issue 67. 2019-11-20. PMID:29340106. |
dorsal hippocampal expression of certain biochemical molecules, including sirtuin 1, erk, pparγ, adiponectin, and bdnf were measured. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
silencing lncrna pvt1 inhibits activation of astrocytes and increases bdnf expression in hippocampus tissues of rats with epilepsy by downregulating the wnt signaling pathway. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
the aim of this study is to investigate the effects of long-chain noncoding rna plasmacytoma variant translocation 1 (pvt1) on the activation of astrocytes and the expression of brain-derived neurotrophic factor (bdnf) in hippocampus tissues of epileptic rats. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
successfully modeled rats were grouped, and their spatial learning and memory, neuronal loss, number of tdt-mediated dutp nick labeling (tunel)-positive cells, and the expression of cleaved-caspase-3, pro-caspase-3, bax, bcl-2, gfap, bdnf, tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β), il-6, axin, and cyclin d1 in hippocampus tissues were evaluated. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
silencing of pvt1 improved spatial learning and memory, decreased neuronal loss, decreased the number of tunel-positive cell, decreased the expression of cleaved-caspase-3 and bax while increased pro-caspase-3 and bcl-2 expression, decreased the expression of gfap, increased the expression of bdnf, decreased the expression of tnf-α, il-1β, and il-6, and decreased the expression of axin and cyclin d1 in hippocampus tissues in epileptic rats. |
2019-11-20 |
2023-08-13 |
rat |
| Teng Zhao, Ying Ding, Min Li, Chunkui Zhou, Weihong Li. Silencing lncRNA PVT1 inhibits activation of astrocytes and increases BDNF expression in hippocampus tissues of rats with epilepsy by downregulating the Wnt signaling pathway. Journal of cellular physiology. 2019-11-20. PMID:30805931. |
our study provides evidence that the inhibition of pvt1 may decrease the loss of neurons, inhibit the activation of astrocytes, and increase the expression of bdnf in hippocampus by downregulating the wnt signaling pathway. |
2019-11-20 |
2023-08-13 |
rat |
| Ji-Xiao Zhu, Wei-Qiong Hu, Shu-Qi Dong, Li-Tao Yi, Jin-Xiang Zeng, Min L. Hippocampal BDNF signaling is required for the antidepressant effects of perillaldehyde. Pharmacological reports : PR. vol 71. issue 3. 2019-11-20. PMID:31003153. |
hippocampal bdnf signaling is required for the antidepressant effects of perillaldehyde. |
2019-11-20 |
2023-08-13 |
mouse |