| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Chen, Can-Can Zhou, Yin Yang, Jian-Wen Liu, Chong-Huai Ya. GM1 Ameliorates Lead-Induced Cognitive Deficits and Brain Damage Through Activating the SIRT1/CREB/BDNF Pathway in the Developing Male Rat Hippocampus. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30414004. |
furthermore, we found that gm1 upregulated the expression of sirt1, creb phosphorylation, and bdnf, which underlie learning and memory in the lead-treated developing rat hippocampus. |
2020-02-04 |
2023-08-13 |
rat |
| Yong-Hyun Ko, Seung-Hwan Kwon, Seok-Yong Lee, Choon-Gon Jan. Isoorientin improves scopolamine-induced cognitive impairments by restoring the cholinergic system, antioxidant defense, and p-CREB/BDNF signaling in the hippocampus and frontal cortex. Archives of pharmacal research. vol 42. issue 8. 2020-02-03. PMID:31350730. |
moreover, western blot results indicated that iso reversed the decreases in expression of phosphorylated camp response element binding (creb) and brain-derived neurotrophic factor (bdnf) in the hippocampus and frontal cortex of scopolamine-treated mice. |
2020-02-03 |
2023-08-13 |
mouse |
| Nasroallah Moradi-Kor, Ali Ghanbari, Hadi Rashidipour, Behpour Yousefi, Ahmad Reza Bandegi, Ali Rashidy-Pou. Beneficial effects of Spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal BDNF and morphological remolding in adult female rats. Hormones and behavior. vol 112. 2020-01-30. PMID:30917909. |
beneficial effects of spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal bdnf and morphological remolding in adult female rats. |
2020-01-30 |
2023-08-13 |
rat |
| Nasroallah Moradi-Kor, Ali Ghanbari, Hadi Rashidipour, Behpour Yousefi, Ahmad Reza Bandegi, Ali Rashidy-Pou. Beneficial effects of Spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal BDNF and morphological remolding in adult female rats. Hormones and behavior. vol 112. 2020-01-30. PMID:30917909. |
the present study investigated the combined protective effects of spirulina platensis (sp), a supplement made from blue-green algae with neuroprotective properties, voluntary exercise (ex) and environmental enrichment (ee) against cognitive deficits, alternations in hippocampal bdnf levels, and abnormal neuronal remodeling in adult female rats (pnd 60) induced by exposure to chronic restraint stress during adolescent period (pnd 30-40). |
2020-01-30 |
2023-08-13 |
rat |
| Nasroallah Moradi-Kor, Ali Ghanbari, Hadi Rashidipour, Behpour Yousefi, Ahmad Reza Bandegi, Ali Rashidy-Pou. Beneficial effects of Spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal BDNF and morphological remolding in adult female rats. Hormones and behavior. vol 112. 2020-01-30. PMID:30917909. |
following the interventions, spatial learning and memory, passive avoidance performance, hippocampal dendritic morphology and bdnf levels were assessed. |
2020-01-30 |
2023-08-13 |
rat |
| Nasroallah Moradi-Kor, Ali Ghanbari, Hadi Rashidipour, Behpour Yousefi, Ahmad Reza Bandegi, Ali Rashidy-Pou. Beneficial effects of Spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal BDNF and morphological remolding in adult female rats. Hormones and behavior. vol 112. 2020-01-30. PMID:30917909. |
stressed rats showed deficits in spatial learning and memory and passive avoidance performance, decreased bdnf levels in the hippocampus, and reduced apical dendritic length and branch points of the ca3 pyramidal neurons. |
2020-01-30 |
2023-08-13 |
rat |
| Nasroallah Moradi-Kor, Ali Ghanbari, Hadi Rashidipour, Behpour Yousefi, Ahmad Reza Bandegi, Ali Rashidy-Pou. Beneficial effects of Spirulina platensis, voluntary exercise and environmental enrichment against adolescent stress induced deficits in cognitive functions, hippocampal BDNF and morphological remolding in adult female rats. Hormones and behavior. vol 112. 2020-01-30. PMID:30917909. |
some treatments even enhanced cognitive functions, and bdnf levels and neuroanatomical remodeling in the hippocampus of non-stressed animals. |
2020-01-30 |
2023-08-13 |
rat |
| Pei-Yi Lin, Ege T Kavalali, Lisa M Monteggi. Genetic Dissection of Presynaptic and Postsynaptic BDNF-TrkB Signaling in Synaptic Efficacy of CA3-CA1 Synapses. Cell reports. vol 24. issue 6. 2020-01-27. PMID:30089265. |
brain-derived neurotrophic factor (bdnf) and its high-affinity receptor, tropomyosin receptor kinase b (trkb), regulate long-term potentiation (ltp) in the hippocampus, although the sites of bdnf-trkb receptors in this process are controversial. |
2020-01-27 |
2023-08-13 |
Not clear |
| Pei-Yi Lin, Ege T Kavalali, Lisa M Monteggi. Genetic Dissection of Presynaptic and Postsynaptic BDNF-TrkB Signaling in Synaptic Efficacy of CA3-CA1 Synapses. Cell reports. vol 24. issue 6. 2020-01-27. PMID:30089265. |
taken together, this direct comparison of presynaptic and postsynaptic bdnf-trkb reveals insight into bdnf release and trkb activation sites in hippocampal ltp. |
2020-01-27 |
2023-08-13 |
Not clear |
| Dragos Niculescu, Kristin Michaelsen-Preusse, Ülkü Güner, René van Dorland, Corette J Wierenga, Christian Lohman. A BDNF-Mediated Push-Pull Plasticity Mechanism for Synaptic Clustering. Cell reports. vol 24. issue 8. 2020-01-27. PMID:30134168. |
here, we show that trkb activation and postsynaptic brain-derived neurotrophic factor (bdnf) are required for synaptic clustering in developing hippocampal neurons. |
2020-01-27 |
2023-08-13 |
Not clear |
| Carmen Ferrer-Pérez, Adriana Castro-Zavala, Miguel Ángel Luján, Joanna Filarowska, Raúl Ballestín, José Miñarro, Olga Valverde, Marta Rodríguez-Aria. Oxytocin prevents the increase of cocaine-related responses produced by social defeat. Neuropharmacology. vol 146. 2020-01-23. PMID:30448423. |
the influence of oxt on the levels of bdnf in the prefrontal cortex (pfc), striatum and hippocampus was also measured. |
2020-01-23 |
2023-08-13 |
Not clear |
| Takayo Odaira, Osamu Nakagawasai, Kohei Takahashi, Wataru Nemoto, Wakana Sakuma, Jia-Rong Lin, Koichi Tan-N. Mechanisms underpinning AMP-activated protein kinase-related effects on behavior and hippocampal neurogenesis in an animal model of depression. Neuropharmacology. vol 150. 2020-01-21. PMID:30914305. |
the expression of phosphorylated ampk, protein kinase c ζ (pkcζ), nuclear factor-kappa b (nf-κb), brain-derived neurotrophic factor (bdnf), and camp response element-binding protein (creb) in the hippocampus was assessed by western blotting. |
2020-01-21 |
2023-08-13 |
mouse |
| Xianhui Kang, Wandong Hong, Kangjie Xie, Hongli Tang, Jingjing Tang, Shan Luo, Wujun Geng, Danyun Ji. Ginsenoside Rb1 pretreatment reverses hippocampal changes in BDNF/TrkB mRNA and protein in rats subjected to acute immobilization stress. Drug design, development and therapy. vol 13. 2020-01-21. PMID:31308626. |
the purpose of this study was to investigate the influence of ginsenoside rb1 on plasma corticosterone (cort) and adrenocorticotropic hormone (acth) levels and hippocampal brain-derived neurotrophic factor (bdnf) and tyrosine kinase b (trkb) levels in rats subjected to acute immobilization stress. |
2020-01-21 |
2023-08-13 |
rat |
| Muneeb Iqbal, Xin-Li Xiao, Salman Zafar, Peng-Bo Yang, Kai-Wei Si, Hua Han, Jian-Xin Liu, Yong Li. Forced Physical Training Increases Neuronal Proliferation and Maturation with Their Integration into Normal Circuits in Pilocarpine Induced Status Epilepticus Mice. Neurochemical research. vol 44. issue 11. 2020-01-21. PMID:31560103. |
changes in bdnf gene methylation and its protein level in hippocampus was also measured at latent stage (2-weeks) to explore underlying pathways involved in increasing neurogenesis. |
2020-01-21 |
2023-08-13 |
mouse |
| Muneeb Iqbal, Xin-Li Xiao, Salman Zafar, Peng-Bo Yang, Kai-Wei Si, Hua Han, Jian-Xin Liu, Yong Li. Forced Physical Training Increases Neuronal Proliferation and Maturation with Their Integration into Normal Circuits in Pilocarpine Induced Status Epilepticus Mice. Neurochemical research. vol 44. issue 11. 2020-01-21. PMID:31560103. |
in conclusion, pt increases hippocampal neurogenesis through increasing bdnf levels by some pathways other than demethylating bdnf cpgs and causes post se newly-born neurons to integrate into normal circuits thus resulting in decreased spontaneous recurrent seizures and enhanced spatial memory. |
2020-01-21 |
2023-08-13 |
mouse |
| Dong Xiao, Li Liu, Yuanjie Li, Jie Ruan, Hanqing Wan. Licorisoflavan A Exerts Antidepressant-Like Effect in Mice: Involvement of BDNF-TrkB Pathway and AMPA Receptors. Neurochemical research. vol 44. issue 9. 2020-01-20. PMID:31278631. |
in chronical-stimulated mice, the licorisoflavan a treatment effectively attenuated the expressions of brain-derived neurotrophic factor (bdnf), tyrosine kinase b (trkb), the phosphorylations of camp response element binding protein (creb), extracellular signal-regulated kinase (erk)-1/2, eukaryotic elongation factor 2 (eef2), mammalian target of rapamycin (mtor), initiation factor 4e-binding protein 1 (4e-bp-1), and p70 ribosomal protein s6 kinase (p70s6k) in hippocampus of cms-induced mice. |
2020-01-20 |
2023-08-13 |
mouse |
| Fatemeh Rouhani, Parvin Khodarahmi, Vahid Nase. NGF, BDNF and Arc mRNA Expression in the Hippocampus of Rats After Administration of Morphine. Neurochemical research. vol 44. issue 9. 2020-01-20. PMID:31376054. |
ngf, bdnf and arc mrna expression in the hippocampus of rats after administration of morphine. |
2020-01-20 |
2023-08-13 |
rat |
| Fatemeh Rouhani, Parvin Khodarahmi, Vahid Nase. NGF, BDNF and Arc mRNA Expression in the Hippocampus of Rats After Administration of Morphine. Neurochemical research. vol 44. issue 9. 2020-01-20. PMID:31376054. |
the purpose of the current study was first to evaluate the effect of acute (1-day) and subchronic (15-days) morphine administration on memory retrieval of rats and second to determine the hippocampal expression of ngf, bdnf and arc genes as potential contributors in the observed effects in each setting. |
2020-01-20 |
2023-08-13 |
rat |
| Fatemeh Rouhani, Parvin Khodarahmi, Vahid Nase. NGF, BDNF and Arc mRNA Expression in the Hippocampus of Rats After Administration of Morphine. Neurochemical research. vol 44. issue 9. 2020-01-20. PMID:31376054. |
we did not detect a significant change in the hippocampal expression of arc, bdnf or ngf genes after a single episode of morphine treatment. |
2020-01-20 |
2023-08-13 |
rat |
| Tsutomu Kataoka, Manabu Fuchikami, Shinji Nojima, Nobuyuki Nagashima, Motoaki Araki, Jun Omura, Tatsuhiro Miyagi, Yasumasa Okamoto, Shigeru Morinob. Combined brain-derived neurotrophic factor with extinction training alleviate impaired fear extinction in an animal model of post-traumatic stress disorder. Genes, brain, and behavior. vol 18. issue 7. 2020-01-16. PMID:30246290. |
bdnf levels were measured by enzyme-linked immunosorbent assay (elisa), and phosphorylation of trkb was measured by immunohistochemistry in the hippocampus and medial prefrontal cortex (mpfc) of sps rats. |
2020-01-16 |
2023-08-13 |
rat |