| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jana Tchekalarova, Dimitrinka Atanasova, Lidia Kortenska, Nikolai Lazarov, Michaela Shishmanova-Doseva, Tzeno Galchev, Pencho Marino. Agomelatine alleviates neuronal loss through BDNF signaling in the post-status epilepticus model induced by kainic acid in rat. Brain research bulletin. vol 147. 2020-04-06. PMID:30738136. |
in the present study, we aimed to explore whether the brain-derived neurotrophic factor (bdnf) in the hippocampus is involved in the neuroprotective effect of ago against the ka-induced se and epileptiform activity four months later in rats. |
2020-04-06 |
2023-08-13 |
rat |
| Jana Tchekalarova, Dimitrinka Atanasova, Lidia Kortenska, Nikolai Lazarov, Michaela Shishmanova-Doseva, Tzeno Galchev, Pencho Marino. Agomelatine alleviates neuronal loss through BDNF signaling in the post-status epilepticus model induced by kainic acid in rat. Brain research bulletin. vol 147. 2020-04-06. PMID:30738136. |
however, both ago and lcm inhibited the expression of bdnf in the mossy fibers and also prevented neuronal loss in the dorsal hippocampal and the piriform cortex after se. |
2020-04-06 |
2023-08-13 |
rat |
| Seung Tack Oh, Quan Feng Liu, Ha Jin Jeong, Seongmi Lee, Manikandan Samidurai, Jihoon Jo, Sok Cheon Pak, Hi-Joon Park, Jongpil Kim, Songhee Jeo. Nasal Cavity Administration of Melanin-Concentrating Hormone Improves Memory Impairment in Memory-Impaired and Alzheimer's Disease Mouse Models. Molecular neurobiology. vol 56. issue 12. 2020-04-06. PMID:31183806. |
to further elucidate the mechanisms of the chronic effect of mch, the levels of phosphorylated creb and gsk3β, and the expression of bdnf, trkb and psd95 were examined in the cerebral cortex and hippocampus. |
2020-04-06 |
2023-08-13 |
mouse |
| Teruaki Nasu, Asako Kubo, Luis F Queme, Kazue Mizumur. A single administration of Neurotropin reduced the elongated immobility time in the forced swimming test of rats exposed to repeated cold stress. Behavioural pharmacology. vol 30. issue 7. 2020-04-06. PMID:31188139. |
decrease of brain-derived neurotrophic factor (bdnf) in the brain is one of the proposed mechanisms for the major depressive disorders, and neurotropin has been reported to restore the decreased bdnf in the hippocampus. |
2020-04-06 |
2023-08-13 |
rat |
| Teruaki Nasu, Asako Kubo, Luis F Queme, Kazue Mizumur. A single administration of Neurotropin reduced the elongated immobility time in the forced swimming test of rats exposed to repeated cold stress. Behavioural pharmacology. vol 30. issue 7. 2020-04-06. PMID:31188139. |
bdnf expression was not changed in the brain areas examined (hippocampus, amygdala, prefrontal cortex, and striatum) either after rcs or by neurotropin injected after rcs. |
2020-04-06 |
2023-08-13 |
rat |
| Jiunn-Ming Sheen, Hong-Ren Yu, You-Lin Tain, Yu-Chieh Chen, Mei-Hsin Hsu, Li-Tung Huan. Young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: Effects of melatonin. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 78. 2020-04-03. PMID:31550497. |
spatial performance, as well as plasma and dorsal hippocampus adma and brain-derived neurotrophic factor (bdnf) concentration, were examined and the effect of melatonin was tested. |
2020-04-03 |
2023-08-13 |
rat |
| Jiunn-Ming Sheen, Hong-Ren Yu, You-Lin Tain, Yu-Chieh Chen, Mei-Hsin Hsu, Li-Tung Huan. Young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: Effects of melatonin. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 78. 2020-04-03. PMID:31550497. |
furthermore, increased adma concentration and decreased bdnf expression were found in the plasma and dorsal hippocampus. |
2020-04-03 |
2023-08-13 |
rat |
| Jiunn-Ming Sheen, Hong-Ren Yu, You-Lin Tain, Yu-Chieh Chen, Mei-Hsin Hsu, Li-Tung Huan. Young rats with increased circulatory asymmetric dimethylarginine exhibited spatial deficit and alterations in dorsal hippocampus brain-derived neurotrophic factor and asymmetric dimethylarginine: Effects of melatonin. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 78. 2020-04-03. PMID:31550497. |
melatonin protected against these effects, alleviating spatial deficit and reducing the changes in plasma and dorsal hippocampus adma and bdnf concentration. |
2020-04-03 |
2023-08-13 |
rat |
| L G Kolik, A V Nadorova, T A Antipova, S V Kruglov, V S Kudrin, A D Durne. Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bulletin of experimental biology and medicine. vol 167. issue 5. 2020-04-03. PMID:31625062. |
selank, peptide analogue of tuftsin, protects against ethanol-induced memory impairment by regulating of bdnf content in the hippocampus and prefrontal cortex in rats. |
2020-04-03 |
2023-08-13 |
rat |
| L G Kolik, A V Nadorova, T A Antipova, S V Kruglov, V S Kudrin, A D Durne. Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bulletin of experimental biology and medicine. vol 167. issue 5. 2020-04-03. PMID:31625062. |
in ex vivo experiments, selank prevented ethanol-induced increase in bdnf content in the hippocampus and frontal cortex (p<0.05). |
2020-04-03 |
2023-08-13 |
rat |
| Louisiana Carolina Ferreira de Meireles, Fernando Galvão, Deena M Walker, Laura Reck Cechinel, Ágnis Iohana de Souza Grefenhagen, Gisele Andrade, Roberta Passos Palazzo, Gisele Agustini Lovatel, Carla Giovanna Basso, Eric J Nestler, Ionara Rodrigues Siqueir. Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31250382. |
we aimed to investigate the effects of aging and different exercise modalities on aversive memory and epigenetic landscapes at brain-derived neurotrophic factor, cfos, and dna methyltransferase 3 alpha (bdnf, cfos, and dnmt3a, respectively) gene promoters in hippocampus of rats. |
2020-04-02 |
2023-08-13 |
rat |
| Louisiana Carolina Ferreira de Meireles, Fernando Galvão, Deena M Walker, Laura Reck Cechinel, Ágnis Iohana de Souza Grefenhagen, Gisele Andrade, Roberta Passos Palazzo, Gisele Agustini Lovatel, Carla Giovanna Basso, Eric J Nestler, Ionara Rodrigues Siqueir. Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31250382. |
aerobic and resistance modalities attenuated age-induced effects on hippocampal bdnf promoter h3k4me3. |
2020-04-02 |
2023-08-13 |
rat |
| Yurika Kobayashi, Eri Segi-Nishid. Search for factors contributing to resistance to the electroconvulsive seizure treatment model using adrenocorticotrophic hormone-treated mice. Pharmacology, biochemistry, and behavior. vol 186. 2020-04-02. PMID:31491434. |
chronic acth treatment suppressed the increase of gene expression such as of bdnf, npy, and drd1 induced by ecs in the hippocampus. |
2020-04-02 |
2023-08-13 |
mouse |
| Pallavi Sharma, Amit Kumar, Damanpreet Sing. Dietary Flavonoids Interaction with CREB-BDNF Pathway: An Unconventional Approach for Comprehensive Management of Epilepsy. Current neuropharmacology. vol 17. issue 12. 2020-04-01. PMID:31400269. |
flavonoids are the polyphenolic compounds which lead to phosphorylation of creb in the hippocampus, followed by increase in extracellular signal regulated kinase (erk) and bdnf. |
2020-04-01 |
2023-08-13 |
Not clear |
| Yun-Ju Huang, Kuan-Hung Lu, Yu-En Lin, Suraphan Panyod, Hsin-Yu Wu, Wan-Ting Chang, Lee-Yan Shee. Garlic essential oil mediates acute and chronic mild stress-induced depression in rats via modulation of monoaminergic neurotransmission and brain-derived neurotrophic factor levels. Food & function. vol 10. issue 12. 2020-04-01. PMID:31735946. |
chronic geo treatment increased hippocampal brain-derived neurotrophic factor (bdnf), c-amp response element binding protein (creb), and protein kinase b (akt) expression, exhibiting its effects via monoamine neurotransmitter modulation and the bdnf-related signaling pathway. |
2020-04-01 |
2023-08-13 |
rat |
| Man-Man Zong, Hong-Mei Yuan, Xue He, Zhi-Qiang Zhou, Xiao-Dong Qiu, Jian-Jun Yang, Mu-Huo J. Disruption of Striatal-Enriched Protein Tyrosine Phosphatase Signaling Might Contribute to Memory Impairment in a Mouse Model of Sepsis-Associated Encephalopathy. Neurochemical research. vol 44. issue 12. 2020-03-30. PMID:31691882. |
the levels of step, phosphorylation of glun2b (pglun2b), the kinases extracellular signal-regulated kinase 1/2 (perk), camp-response element binding protein (creb), synaptophysin, brain derived neurotrophic factor (bdnf), and post-synaptic density protein 95 (psd95) in the hippocampus, prefrontal cortex, and striatum were determined at the indicated time points. |
2020-03-30 |
2023-08-13 |
mouse |
| Victor Celso Cavalcanti Capibaribe, Auriana Serra Vasconcelos Mallmann, Iardja Stéfane Lopes, Iris Cristina Maia Oliveira, Natalia Ferreira de Oliveira, Raquell de Castro Chaves, Mariana Lima Fernandes, Mariana Albuquerque de Araujo, Daniel Moreira Alves da Silva, José Tiago Valentim, Adriano José Maia Chaves Filho, Danielle Silveira Macêdo, Silvânia Maria Mendes de Vasconcelos, Alyne Mara Rodrigues de Carvalho, Francisca Cléa Florenço de Sous. Thymol reverses depression-like behaviour and upregulates hippocampal BDNF levels in chronic corticosterone-induced depression model in female mice. The Journal of pharmacy and pharmacology. vol 71. issue 12. 2020-03-27. PMID:31608449. |
thymol reverses depression-like behaviour and upregulates hippocampal bdnf levels in chronic corticosterone-induced depression model in female mice. |
2020-03-27 |
2023-08-13 |
mouse |
| Micaela Domingues, Angela Maria Casaril, Paloma Taborda Birmann, Suely Ribeiro Bampi, Darling de Andrade Lourenço, Beatriz M Vieira, Luiz H Dapper, Eder J Lenardão, Mariana Sonego, Tiago Collares, Fabiana K Seixas, César Augusto Brüning, Lucielli Savegnag. Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice. Behavioural brain research. vol 366. 2020-03-26. PMID:30877027. |
additionally, mpi prevented ars-induced downregulation of brain-derived neurotrophic factor (bdnf), increased reactive oxygen/nitrogen species generation and lipid peroxidation in prefrontal cortex and hippocampus of mice. |
2020-03-26 |
2023-08-13 |
mouse |
| Juliano Viana Borges, Betânia Souza de Freitas, Vinicius Antoniazzi, Cristophod de Souza Dos Santos, Kelem Vedovelli, Vivian Naziaseno Pires, Leticia Paludo, Maria Noêmia Martins de Lima, Elke Bromber. Social isolation and social support at adulthood affect epigenetic mechanisms, brain-derived neurotrophic factor levels and behavior of chronically stressed rats. Behavioural brain research. vol 366. 2020-03-26. PMID:30880220. |
this study investigated the effects of social isolation and social buffering on hippocampal epigenetic mechanisms, bdnf levels and behavioral responses of chronically stressed young adult rats. |
2020-03-26 |
2023-08-13 |
rat |
| Juliano Viana Borges, Betânia Souza de Freitas, Vinicius Antoniazzi, Cristophod de Souza Dos Santos, Kelem Vedovelli, Vivian Naziaseno Pires, Leticia Paludo, Maria Noêmia Martins de Lima, Elke Bromber. Social isolation and social support at adulthood affect epigenetic mechanisms, brain-derived neurotrophic factor levels and behavior of chronically stressed rats. Behavioural brain research. vol 366. 2020-03-26. PMID:30880220. |
hippocampal h3k9 and h4k12 acetylation, hdac5 expression and bdnf levels were evaluated. |
2020-03-26 |
2023-08-13 |
rat |