| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tae-Woon Kim, Sang-Seo Park, Mal-Soon Shin, Hye-Sang Park, Seung-Soo Bae. Treadmill exercise ameliorates social isolation-induced memory impairment by enhancing silent information regulator-1 expression in rats. Journal of exercise rehabilitation. vol 16. issue 3. 2020-09-28. PMID:32724779. |
hippocampal bdnf and trkb expression was decreased in the rats of social isolation group. |
2020-09-28 |
2023-08-13 |
rat |
| Jianxin Li, Ling Chen, Gaowen Li, Xiaojuan Chen, Sisi Hu, Liang Zheng, Victor Luria, Jinpeng Lv, Yindi Sun, Ying Xu, Yingcong Y. Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32733195. |
our previous study suggested that acute treatment with a novel curcumin derivative j147 exhibited antidepressant-like effects by increasing brain derived neurotrophic factor (bdnf) level in the hippocampus of mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Andrzej Wróbel, Anna Serefko, Aleksandra Szopa, Daniela Ulrich, Ewa Poleszak, Tomasz Rechberge. O-1602, an Agonist of Atypical Cannabinoid Receptors GPR55, Reverses the Symptoms of Depression and Detrusor Overactivity in Rats Subjected to Corticosterone Treatment. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32733244. |
the o-1602 treatment also reversed the abnormal changes in the bladder, hippocampal or urine values of cgrp, oct3, vacht, bdnf, and ngf. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
effects of vortioxetine on depression model rats and expression of bdnf and trk b in hippocampus. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
effects of vortioxetine on the expression of brain-derived neurotrophic factor (bdnf) and tyrosine kinase b (trk b) in hippocampus of depressive rats were investigated. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
the expression of bdnf and trk b in rat hippocampus was detected by enzyme-linked immuno sorbent assay. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
sevoflurane reduced brain-derived neurotrophic factor (bdnf), acetyl histone h3 (ac-h3), and ac-h4 levels and increased histone deacetylases-2 (hdac2) and hdac3 levels in the hippocampus of the offspring on postnatal day 1 (p1) and p35. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
ee alleviated sevoflurane-induced cognitive dysfunction and increased hippocampal bdnf, ac-h3, and ac-h4. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
exposure to 2.5% sevoflurane for 3 h during late-pregnancy decreased hippocampal bdnf, ac-h3, and ac-h4 in the offspring but had no effect on cognitive function. |
2020-09-28 |
2023-08-13 |
rat |
| Ying Yu, Jianxiong Jian. COX-2/PGE Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913950. |
cox-2/pge the objective of this study was to identify the signaling pathway that is immediately triggered by status epilepticus (se) and in turn contributes to the excessive brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase receptor b (trkb) signaling within the hippocampus. |
2020-09-28 |
2023-08-13 |
Not clear |
| Henry M Corpuz, Hiroshi Fujii, Soichiro Nakamura, Shigeru Katayam. Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus. Brain research. vol 1720. 2020-09-24. PMID:31278934. |
frp pretreatment suppressed scopolamine-induced cognitive impairment in passive-avoidance test and significantly upregulated levels of brain-derived neurotrophic factor (bdnf) and induced the phosphorylation of camp response element binding (creb) protein and extracellular signal-regulated kinase (erk) in the hippocampus of scopolamine-treated mice. |
2020-09-24 |
2023-08-13 |
mouse |
| Tahereh Ghadiri, Gelareh Vakilzadeh, Vahid Hajali, Fariba Khodaghol. Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus. Neuroscience letters. vol 709. 2020-09-24. PMID:31325580. |
in line with behavioral alterations, 32 mg/kg progesterone enhanced the amount of nrf2 and ho-1 proteins and decreased the level of nf-kb, bdnf, caspase 3 and ratio of bax/bcl-2 in the ipsilateral hippocampus. |
2020-09-24 |
2023-08-13 |
rat |
| Julieta Paola Aguggia, Marta Magdalena Suárez, María Angélica Rivarol. Multiparity Dampened the Neurobehavioral Consequences of Mother-Pup Separation Stress in Dams. Neuroscience. vol 416. 2020-09-24. PMID:31377452. |
cell survival and proliferation in the dentate gyrus, as well as bdnf expression in the hippocampus, were evaluated by immunohistochemistry as possible candidates for mediating brain plasticity in response to reproductive experience and stress. |
2020-09-24 |
2023-08-13 |
rat |
| Ethiane Segabinazi, Christiano Spindler, André Luís Ferreira de Meireles, Francele Valente Piazza, Filipe Mega, Gabriela Dos Santos Salvalaggio, Matilde Achaval, Simone Marcuzz. Effects of Maternal Physical Exercise on Global DNA Methylation and Hippocampal Plasticity of Rat Male Offspring. Neuroscience. vol 418. 2020-09-24. PMID:31473277. |
at p53, hippocampal global dna methylation, survival of progenitor cells (brdu), brain-derived neurotrophic factor (bdnf) and reelin levels were measured. |
2020-09-24 |
2023-08-13 |
rat |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the bdnf signalling pathway and neurogenesis in the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
in addition, an impairment in hippocampal neurogenesis that paralleled a reduced bdnf level in the hippocampus was observed in the mice that were subjected with csds for 3 weeks, while treatment with ds reversed these changes. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
moreover, ds treatment significantly upregulated bdnf, ptrkb/trkb, pakt/akt, ppi3k/pi3k, pcreb/creb, perk1/2/erk1/2 and pmtor/mtor protein expression in the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
in conclusion, our results showed that ds exerts antidepressant-like effects in mice with csds-induced depression, that the effects may be mediated by the normalization of monoamine neurotransmitter levels, the prevention of hpa axis dysfunction and the impairment of hippocampal neurogenesis, and that this occurs partly through the ability of ds to enhance bdnf expression by increasing the trkb/creb/erk pathway and the pi3k/akt/mtor pathway. |
2020-09-24 |
2023-08-13 |
mouse |
| Javad Riyahi, Behrouz Abdoli, Abbas Haghparast, Laura Petrosin. Intergenerational effect of parental spatial training on offspring learning: Evidence for sex differences in memory function. Brain research bulletin. vol 153. 2020-09-24. PMID:31585156. |
also, erk1/2, bdnf, syt1 and h3k14ac levels in the hippocampus of offspring were analyzed. |
2020-09-24 |
2023-08-13 |
Not clear |
| Javad Riyahi, Behrouz Abdoli, Abbas Haghparast, Laura Petrosin. Intergenerational effect of parental spatial training on offspring learning: Evidence for sex differences in memory function. Brain research bulletin. vol 153. 2020-09-24. PMID:31585156. |
we observed that father's spatial training increased acetylated h3k14 in male offspring's hippocampus, suggesting that histone acetylation may upregulate the expression of bdnf and phosphorylated erk1/2 in the male offspring of father trained and thus contribute to the enhancement of spatial learning and memory. |
2020-09-24 |
2023-08-13 |
Not clear |