| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Rashidy-Pour, Kowsar Bavarsad, Hossein Miladi-Gorji, Zahra Seraj, Abbas Ali Vafae. Voluntary exercise and estradiol reverse ovariectomy-induced spatial learning and memory deficits and reduction in hippocampal brain-derived neurotrophic factor in rats. Pharmacology, biochemistry, and behavior. vol 187. 2020-07-21. PMID:31697961. |
exercise significantly improved performance during both training and the retention of the water-maze task and increased hippocampal bdnf. |
2020-07-21 |
2023-08-13 |
rat |
| Jun Yamada, Shozo Jinn. Potential link between antidepressant-like effects of ketamine and promotion of adult neurogenesis in the ventral hippocampus of mice. Neuropharmacology. vol 158. 2020-07-20. PMID:31310776. |
the induction of expression of glun2b subunit of the nmdar, phosphorylated mammalian target of rapamycin (p-mtor), glua1 subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampar), and brain derived neurotrophic factor (bdnf), by ketamine was greater in the ventral hippocampus than in the dorsal hippocampus. |
2020-07-20 |
2023-08-13 |
mouse |
| Jun Yamada, Shozo Jinn. Potential link between antidepressant-like effects of ketamine and promotion of adult neurogenesis in the ventral hippocampus of mice. Neuropharmacology. vol 158. 2020-07-20. PMID:31310776. |
furthermore, ventral-dominant induction of the glun2b subunit of nmdar, p-mtor, glua1 subunit of ampar, and bdnf, in the hippocampus may underlie the unique antidepressant-like effects of ketamine. |
2020-07-20 |
2023-08-13 |
mouse |
| Henry L Hallock, Henry M Quillian, Yishan Mai, Kristen R Maynard, Julia L Hill, Keri Martinowic. Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 13. 2020-07-08. PMID:31170726. |
brain-derived neurotrophic factor (bdnf) signaling regulates synaptic plasticity in the hippocampus (hc) and prefrontal cortex (pfc), and has been extensively linked with fear memory expression in rodents. |
2020-07-08 |
2023-08-13 |
mouse |
| Aanchal Aggarwal, Nishtha Sharma, Rajat Sandhir, Vikas Rish. S-nitrosoglutathione prevents cognitive impairment through epigenetic reprogramming in ovariectomised mice. Biochemical pharmacology. vol 168. 2020-07-06. PMID:31374192. |
reduced h3 acetylation triggers epigenetic repression of brain derived neurotrophic factor (bdnf) in cortex and hippocampus of ovx mice that may be responsible for neuronal damage and cognitive impairment. |
2020-07-06 |
2023-08-13 |
mouse |
| Yalin Zhou, Minjia Zhang, Wei Liu, Yong Li, Yong Qin, Yajun X. Transgenerational transmission of neurodevelopmental disorders induced by maternal exposure to PM2.5. Chemosphere. vol 255. 2020-07-02. PMID:32387734. |
and the hypermethylation of bdnf promoter Ⅳ and downregulated expression of bdnf in hippocampus were stably transmitted across the generations until the third generation. |
2020-07-02 |
2023-08-13 |
Not clear |
| Marta Andreatta, Dorothea Neueder, Hannah Genheimer, Miriam A Schiele, Christoph Schartner, Jürgen Deckert, Katharina Domschke, Andreas Reif, Matthias J Wieser, Paul Paul. Human BDNF rs6265 polymorphism as a mediator for the generalization of contextual anxiety. Journal of neuroscience research. vol 97. issue 3. 2020-07-01. PMID:30402941. |
the met allele of the human brain-derived neurotrophic factor (bdnf) gene might be a risk factor for anxiety disorders and is associated with reduced hippocampal volume. |
2020-07-01 |
2023-08-13 |
human |
| Yubao Fan, Yuxin Ma, Weiling Huang, Xiaohui Cheng, Ningxin Gao, Guoying Li, Sumin Tia. Up-regulation of TREM2 accelerates the reduction of amyloid deposits and promotes neuronal regeneration in the hippocampus of amyloid beta1-42 injected mice. Journal of chemical neuroanatomy. vol 97. 2020-06-26. PMID:30790627. |
various immunohistochemical techniques and western blot analyses were applied to examine expressions of trem2, microglia, aβ, neuronal migration protein doublecortin (dcx) and bdnf in the hippocampus of mice. |
2020-06-26 |
2023-08-13 |
mouse |
| Zhuang Miao, Jianghong Zhang, Yuanyuan Li, Xianfeng Li, Wei Song, Zhong Sheng Sun, Yan Wan. Presence of the pregnant partner regulates microRNA-30a and BDNF levels and protects male mice from social defeat-induced abnormal behaviors. Neuropharmacology. vol 159. 2020-06-26. PMID:30946846. |
the levels of bdnf, together with its primary transcripts, were down-regulated in the hippocampus of male mice with csds and these decreases were ameliorated by the presence of their pregnant partners. |
2020-06-26 |
2023-08-13 |
mouse |
| Karem H Alzoubi, Zeinab Y Al Subeh, Omar F Khabou. Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. Behavioural brain research. vol 369. 2020-06-23. PMID:31047921. |
in the current study, the effect of etazolate on oxidative stress parameters, bdnf, and histone acetylation in the hippocampus were evaluated in a rat model of ptsd. |
2020-06-23 |
2023-08-13 |
rat |
| Karem H Alzoubi, Zeinab Y Al Subeh, Omar F Khabou. Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. Behavioural brain research. vol 369. 2020-06-23. PMID:31047921. |
at the end of the treatment period, the hippocampus was dissected and oxidative stress biomarkers (gsh, gssg, gpx and tbars), bdnf protein level, and histone acetylation were assessed. |
2020-06-23 |
2023-08-13 |
rat |
| Karem H Alzoubi, Zeinab Y Al Subeh, Omar F Khabou. Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. Behavioural brain research. vol 369. 2020-06-23. PMID:31047921. |
results revealed that ptsd potentiated oxidative stress in the hippocampus and induced significant reductions in bdnf level and histones acetylation (p < 0.05). |
2020-06-23 |
2023-08-13 |
rat |
| Zhi-Long Zhang, Yu-Gang Gao, Pu Zang, Pei-Pei Gu, Yan Zhao, Zhong-Mei He, Hong-Yan Zh. [Research progress on mechanism of gastrodin and p-hydroxybenzyl alcohol on central nervous system]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 2. 2020-06-23. PMID:32237313. |
they alleviate hippocampal neuronal toxicity mainly by regulating a variety of neurotransmitters, such as acetylcholine, glutamic acid(glu), γ-aminobutyric acid(gaba), serotonin(5-ht), dopamine(da), norepinephrine(ne), 5-indoleacetic acid(5-hiaa), high vanillic acid(hva) and dihydroxyphenylacetic acid(dopac), pro-inflammatory cell growth factors, such as il-1β, il-6 and tnf-α and relevant receptor functions, and exert neuropharmacological effects by effectively increasing mrna expressions of brain neurotrophic factors, such as bdnf and gdnf, and further inhibiting the apoptosis of damaged neurons. |
2020-06-23 |
2023-08-13 |
Not clear |
| Hannah V Oakes, Carley E DeVee, Brandon Farmer, Serena A Allen, Alexis N Hall, Tucker Ensley, Kristen Medlock, Angela Hanley, Brooks B Pon. Neurogenesis within the hippocampus after chronic methylphenidate exposure. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 2. 2020-06-22. PMID:30370451. |
to investigate the mechanism for this effect, we examined levels of proteins linked to cell proliferation in the hippocampus, including brain-derived neurotrophic factor (bdnf), glial cell line-derived neurotrophic factor (gdnf), vascular endothelial growth factor (vegf), tropomyosin receptor kinase b (trkb), and beta-catenin. |
2020-06-22 |
2023-08-13 |
mouse |
| Amanda Brondani Mucellini, Daniela Pereira Laureano, Patrícia Pelufo Silveira, Gilberto Luiz Sanvitt. Maternal and post-natal obesity alters long-term memory and hippocampal molecular signaling of male rat. Brain research. vol 1708. 2020-06-15. PMID:30571979. |
the aim of this study was to investigate whether maternal cafeteria ingestion interferes with long-term memory-related behaviors and hippocampal brain-derived neurotrophic factor (bdnf) signaling in the offspring, and if there is a cumulative effect with the exposure to cafeteria diet during the life-course of the pups. |
2020-06-15 |
2023-08-13 |
rat |
| Amanda Brondani Mucellini, Daniela Pereira Laureano, Patrícia Pelufo Silveira, Gilberto Luiz Sanvitt. Maternal and post-natal obesity alters long-term memory and hippocampal molecular signaling of male rat. Brain research. vol 1708. 2020-06-15. PMID:30571979. |
there were no significant differences between groups in the hippocampal concentrations of bdnf and camp response element binding protein (creb) in puberty or adulthood, but the concentration of hippocampal ras-raf-mek-mitogen-activated protein kinase (mapk) was higher in caf-caf pubescent offspring when compared to the con-con group. |
2020-06-15 |
2023-08-13 |
rat |
| Andia Ebrahimzadeh, Sara Yousefi Moghadam, Hanieh Rahimi, Majid Motaghinejad, Manijeh Motevalian, Sepideh Safari, Mobina Abbasi Mesrabad. Crocin acts as a neuroprotective mediator against methylphenidate‑induced neurobehavioral and neurochemical sequelae: Possible role of the CREB-BDNF signaling pathway. Acta neurobiologiae experimentalis. vol 79. issue 4. 2020-06-15. PMID:31885392. |
hippocampal neurotoxicity parameters and levels of bdnf and creb were evaluated. |
2020-06-15 |
2023-08-13 |
rat |
| Andia Ebrahimzadeh, Sara Yousefi Moghadam, Hanieh Rahimi, Majid Motaghinejad, Manijeh Motevalian, Sepideh Safari, Mobina Abbasi Mesrabad. Crocin acts as a neuroprotective mediator against methylphenidate‑induced neurobehavioral and neurochemical sequelae: Possible role of the CREB-BDNF signaling pathway. Acta neurobiologiae experimentalis. vol 79. issue 4. 2020-06-15. PMID:31885392. |
mph treatment decreased levels of the reduced form of glutathione (gsh), p‑creb, bcl‑2, and bdnf in the hippocampus. |
2020-06-15 |
2023-08-13 |
rat |
| Eric Harvey, Matthew Blurton-Jones, Pamela J Kenned. Hippocampal BDNF regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. Hippocampus. vol 29. issue 11. 2020-06-12. PMID:31206907. |
hippocampal bdnf regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. |
2020-06-12 |
2023-08-13 |
rat |
| Wenqian Yang, Qulian Guo, Jingyi Li, Ximei Wang, Bingbing Pan, Yunjiao Wang, Lei Wu, Jianqin Yan, Zhigang Chen. microRNA-124 attenuates isoflurane-induced neurological deficits in neonatal rats via binding to EGR1. Journal of cellular physiology. vol 234. issue 12. 2020-06-11. PMID:31131895. |
the treatment of mir-124 agomir improved rats' spatial learning and memory ability and notably increased hippocampal neuron viability and resistance to apoptosis, corresponding to an increased brain-derived neurotrophic factor (bdnf) expression, inhibited expression of proapoptotic factors (cleaved-caspase-3 and bax), and enhanced the expression of antiapoptotic factor (bcl-2). |
2020-06-11 |
2023-08-13 |
rat |