| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hannah V Oakes, Carley E DeVee, Brandon Farmer, Serena A Allen, Alexis N Hall, Tucker Ensley, Kristen Medlock, Angela Hanley, Brooks B Pon. Neurogenesis within the hippocampus after chronic methylphenidate exposure. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 2. 2020-06-22. PMID:30370451. |
to investigate the mechanism for this effect, we examined levels of proteins linked to cell proliferation in the hippocampus, including brain-derived neurotrophic factor (bdnf), glial cell line-derived neurotrophic factor (gdnf), vascular endothelial growth factor (vegf), tropomyosin receptor kinase b (trkb), and beta-catenin. |
2020-06-22 |
2023-08-13 |
mouse |
| Amanda Brondani Mucellini, Daniela Pereira Laureano, Patrícia Pelufo Silveira, Gilberto Luiz Sanvitt. Maternal and post-natal obesity alters long-term memory and hippocampal molecular signaling of male rat. Brain research. vol 1708. 2020-06-15. PMID:30571979. |
the aim of this study was to investigate whether maternal cafeteria ingestion interferes with long-term memory-related behaviors and hippocampal brain-derived neurotrophic factor (bdnf) signaling in the offspring, and if there is a cumulative effect with the exposure to cafeteria diet during the life-course of the pups. |
2020-06-15 |
2023-08-13 |
rat |
| Amanda Brondani Mucellini, Daniela Pereira Laureano, Patrícia Pelufo Silveira, Gilberto Luiz Sanvitt. Maternal and post-natal obesity alters long-term memory and hippocampal molecular signaling of male rat. Brain research. vol 1708. 2020-06-15. PMID:30571979. |
there were no significant differences between groups in the hippocampal concentrations of bdnf and camp response element binding protein (creb) in puberty or adulthood, but the concentration of hippocampal ras-raf-mek-mitogen-activated protein kinase (mapk) was higher in caf-caf pubescent offspring when compared to the con-con group. |
2020-06-15 |
2023-08-13 |
rat |
| Andia Ebrahimzadeh, Sara Yousefi Moghadam, Hanieh Rahimi, Majid Motaghinejad, Manijeh Motevalian, Sepideh Safari, Mobina Abbasi Mesrabad. Crocin acts as a neuroprotective mediator against methylphenidate‑induced neurobehavioral and neurochemical sequelae: Possible role of the CREB-BDNF signaling pathway. Acta neurobiologiae experimentalis. vol 79. issue 4. 2020-06-15. PMID:31885392. |
hippocampal neurotoxicity parameters and levels of bdnf and creb were evaluated. |
2020-06-15 |
2023-08-13 |
rat |
| Andia Ebrahimzadeh, Sara Yousefi Moghadam, Hanieh Rahimi, Majid Motaghinejad, Manijeh Motevalian, Sepideh Safari, Mobina Abbasi Mesrabad. Crocin acts as a neuroprotective mediator against methylphenidate‑induced neurobehavioral and neurochemical sequelae: Possible role of the CREB-BDNF signaling pathway. Acta neurobiologiae experimentalis. vol 79. issue 4. 2020-06-15. PMID:31885392. |
mph treatment decreased levels of the reduced form of glutathione (gsh), p‑creb, bcl‑2, and bdnf in the hippocampus. |
2020-06-15 |
2023-08-13 |
rat |
| Eric Harvey, Matthew Blurton-Jones, Pamela J Kenned. Hippocampal BDNF regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. Hippocampus. vol 29. issue 11. 2020-06-12. PMID:31206907. |
hippocampal bdnf regulates a shift from flexible, goal-directed to habit memory system function following cocaine abstinence. |
2020-06-12 |
2023-08-13 |
rat |
| Wenqian Yang, Qulian Guo, Jingyi Li, Ximei Wang, Bingbing Pan, Yunjiao Wang, Lei Wu, Jianqin Yan, Zhigang Chen. microRNA-124 attenuates isoflurane-induced neurological deficits in neonatal rats via binding to EGR1. Journal of cellular physiology. vol 234. issue 12. 2020-06-11. PMID:31131895. |
the treatment of mir-124 agomir improved rats' spatial learning and memory ability and notably increased hippocampal neuron viability and resistance to apoptosis, corresponding to an increased brain-derived neurotrophic factor (bdnf) expression, inhibited expression of proapoptotic factors (cleaved-caspase-3 and bax), and enhanced the expression of antiapoptotic factor (bcl-2). |
2020-06-11 |
2023-08-13 |
rat |
| Natalie Groves, Imogen O'Keeffe, Wendy Lee, Alexandra Toft, Daniel Blackmore, Saurabh Bandhavkar, Elizabeth J Coulson, Perry F Bartlett, Dhanisha J Jhaver. Blockade of TrkB but not p75 Developmental neurobiology. vol 79. issue 9-10. 2020-06-11. PMID:31886631. |
blockade of trkb but not p75 brain-derived neurotrophic factor (bdnf) signaling plays a major role in the regulation of hippocampal neurogenesis in the adult brain. |
2020-06-11 |
2023-08-13 |
Not clear |
| Linlin Fan, Lingling Chen, Zhi Liang, Hongkun Bao, Dan Wang, Yilong Dong, Shangyong Zheng, Chunjie Xiao, Jing Du, Hongliang L. A Polysaccharide Extract from Maitake Culinary-Medicinal Mushroom, Grifola frondosa (Agaricomycetes) Ameliorates Learning and Memory Function in Aluminum Chloride-Induced Amnesia in Mice. International journal of medicinal mushrooms. vol 21. issue 11. 2020-06-10. PMID:32450016. |
furthermore, pgm treatment significantly enhanced the level of ampar and bdnf in the hippocampus, while suppressing the tau protein hyperphosphorylation at the ser396 site. |
2020-06-10 |
2023-08-13 |
mouse |
| Durany, Michel, Kurt, Cruz-Sánchez, Cervós-Navarro, Riedere. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 8. 2020-06-01. PMID:11154850. |
in the present study, we investigated the levels of brain-derived neurotrophic factor (bdnf) and neurotrophin-3 (nt-3) in post-mortem brain tissue of alzheimer's disease (ad) patients, and we observed a significant increase of bdnf concentration in hippocampus and parietal cortex of ad patients, as well as a negative correlation between nt-3 levels and age in hippocampus and putamen of control subjects, and for bdnf in frontal cortex. |
2020-06-01 |
2023-08-12 |
human |
| Pamela Lopes da Cunha, Maria Eugenia Villar, Fabricio Ballarini, Ramiro Tintorelli, Haydée Ana María Viol. Spatial object recognition memory formation under acute stress. Hippocampus. vol 29. issue 6. 2020-06-01. PMID:30295349. |
the effect induced by stress was dependent on the activation of glucocorticoid- and mineralocorticoid-receptors, brain-derived neurotrophic factor (bdnf) and protein synthesis in the dorsal hippocampus. |
2020-06-01 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Alireza Mohammadnia, Masoumeh Dadkhah, Hakimeh Saadat. Sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: The role of hippocampal BDNF level. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2020-05-31. PMID:32416621. |
sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: the role of hippocampal bdnf level. |
2020-05-31 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Alireza Mohammadnia, Masoumeh Dadkhah, Hakimeh Saadat. Sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: The role of hippocampal BDNF level. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2020-05-31. PMID:32416621. |
exposure to enriched environment (ee) has been indicated to enhance cognitive functions, hippocampal neural plasticity, neurogenesis, long-term potentiation, and levels of the brain-derived neurotrophic factor (bdnf) in laboratory animals. |
2020-05-31 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Alireza Mohammadnia, Masoumeh Dadkhah, Hakimeh Saadat. Sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: The role of hippocampal BDNF level. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2020-05-31. PMID:32416621. |
therefore, the present study was designed to compare the effects of ee during adolescence (pnd21-pnd60) on novel objective recognition memory (norm), anxiety-like behaviors, and hippocampal bdnf mrna level in the adult male and female rats. |
2020-05-31 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Alireza Mohammadnia, Masoumeh Dadkhah, Hakimeh Saadat. Sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: The role of hippocampal BDNF level. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2020-05-31. PMID:32416621. |
additionally, our results indicated an augmented bdnf level in the hippocampus of male and female rats. |
2020-05-31 |
2023-08-13 |
rat |
| Nona Sakhaie, Farshid Sadegzadeh, Alireza Mohammadnia, Masoumeh Dadkhah, Hakimeh Saadat. Sex-dependent effects of postweaning exposure to an enriched environment on novel objective recognition memory and anxiety-like behaviors: The role of hippocampal BDNF level. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2020-05-31. PMID:32416621. |
in conclusion, adolescent exposure to ee has sex-dependent effects on cognitive functions and anxiety-like behaviors and increases bdnf mrna expression in the hippocampus of both male and female rats; thus, bdnf is an important factor that can mediate the beneficial effects of ee and running exercise on cognitive functions and psychiatric traits. |
2020-05-31 |
2023-08-13 |
rat |
| Masaaki Tanichi, Kunio Shimizu, Shingo Enomoto, Minori Koga, Hiroyuki Toda, Masanori Nagamine, Eiji Suzuki, Masashi Nibuy. The effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder. European journal of pharmacology. vol 865. 2020-05-20. PMID:31654623. |
additionally, western blot analyses using brain-derived neurotrophic factor (bdnf) monoclonal antibody revealed a decreased expression of bdnf protein, in the hippocampal region of the rats, due to foot-shock traumatization and a significantly increased expression of bdnf protein after oral epa supplementation. |
2020-05-20 |
2023-08-13 |
rat |
| Masaaki Tanichi, Kunio Shimizu, Shingo Enomoto, Minori Koga, Hiroyuki Toda, Masanori Nagamine, Eiji Suzuki, Masashi Nibuy. The effects of eicosapentaenoic acid dietary supplementation on behavioral parameters and expression of hippocampal brain-derived neurotrophic factor in an animal model of post-traumatic stress disorder. European journal of pharmacology. vol 865. 2020-05-20. PMID:31654623. |
the results indicate a possibility that alteration of the numbing/avoidance behavior parallels the expression of hippocampal bdnf in the rat brain. |
2020-05-20 |
2023-08-13 |
rat |
| Yue Han, Lijuan Zhang, Qiaozhi Wang, Dingding Zhang, Qiuying Zhao, Jinqiang Zhang, Lei Xie, Guangyi Liu, Zili Yo. Minocycline inhibits microglial activation and alleviates depressive-like behaviors in male adolescent mice subjected to maternal separation. Psychoneuroendocrinology. vol 107. 2020-05-18. PMID:31078757. |
these changes in inflammatory processes correlated with changes in neurogenesis and bdnf expression in the hippocampus. |
2020-05-18 |
2023-08-13 |
mouse |
| Yi-Yung Hung, Ya-Ling Huang, Chawnshang Chang, Hong-Yo Kan. Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression. Cells. vol 8. issue 9. 2020-05-14. PMID:31480771. |
adding the antiandrogen flutamide with the stress hormone corticosterone can additively decrease bdnf mrna in mouse hippocampus mhippoe-14 cells, which can then be reversed via down-regulating the mir-204-5p expression. |
2020-05-14 |
2023-08-13 |
mouse |