| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tong Wu, Xiao-Yu Sun, Xiu Yang, Le Liu, Kun Tong, Ya Gao, Jing-Ru Hao, Jing Cao, Can Ga. Histone H3K9 Trimethylation Downregulates the Expression of Brain-Derived Neurotrophic Factor in the Dorsal Hippocampus and Impairs Memory Formation During Anaesthesia and Surgery. Frontiers in molecular neuroscience. vol 12. 2020-09-29. PMID:31708739. |
bdnf expression was decreased in the hippocampus after anaesthesia and surgery. |
2020-09-29 |
2023-08-13 |
Not clear |
| Parisa Habibi, Shirin Babri, Nasser Ahmadiasl, Hadi Yousef. Effects of genistein and swimming exercise on spatial memory and expression of microRNA 132, BDNF, and IGF-1 genes in the hippocampus of ovariectomized rats. Iranian journal of basic medical sciences. vol 20. issue 8. 2020-09-28. PMID:29085576. |
effects of genistein and swimming exercise on spatial memory and expression of microrna 132, bdnf, and igf-1 genes in the hippocampus of ovariectomized rats. |
2020-09-28 |
2023-08-13 |
rat |
| Parisa Habibi, Shirin Babri, Nasser Ahmadiasl, Hadi Yousef. Effects of genistein and swimming exercise on spatial memory and expression of microRNA 132, BDNF, and IGF-1 genes in the hippocampus of ovariectomized rats. Iranian journal of basic medical sciences. vol 20. issue 8. 2020-09-28. PMID:29085576. |
the aim of the present study was to investigate the effects of genistein and exercise on the spatial memory and expression of microrna-132, bdnf, and igf-1 in the hippocampus of ovariectomized rats. |
2020-09-28 |
2023-08-13 |
rat |
| Patrick Nasrallah, Edwina Abou Haidar, Joseph S Stephan, Lauretta El Hayek, Nabil Karnib, Mohamad Khalifeh, Nour Barmo, Vanessa Jabre, Rouba Houbeika, Anthony Ghanem, Jason Nasser, Nadine Zeeni, Maya Bassil, Sama F Sleima. Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling. Neurobiology of stress. vol 11. 2020-09-28. PMID:31193350. |
bcaa promoted resilience to chronic stress, rescued social avoidance behaviors and increased hippocampal bdnf levels and trkb activation. |
2020-09-28 |
2023-08-13 |
mouse |
| Patrick Nasrallah, Edwina Abou Haidar, Joseph S Stephan, Lauretta El Hayek, Nabil Karnib, Mohamad Khalifeh, Nour Barmo, Vanessa Jabre, Rouba Houbeika, Anthony Ghanem, Jason Nasser, Nadine Zeeni, Maya Bassil, Sama F Sleima. Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling. Neurobiology of stress. vol 11. 2020-09-28. PMID:31193350. |
interestingly, we found that bcaa activate the exercise-regulated pgc1a/fndc5 pathway known to induce hippocampal bdnf signaling. |
2020-09-28 |
2023-08-13 |
mouse |
| Paula M Q Bellozi, Renan Pelição, Matheus C Santos, Isabel V A Lima, Soraya W Saliba, Érica L M Vieira, Alline C Campos, Antônio L Teixeira, Antônio C P de Oliveira, Ester M Nakamura-Palacios, Lívia C M Rodrigue. URB597 ameliorates the deleterious effects induced by binge alcohol consumption in adolescent rats. Neuroscience letters. vol 711. 2020-09-28. PMID:31374324. |
the chronic binge alcohol administration increased the interferon (ifn)-γ and tumor necrosis factor (tnf)-α levels in the pfc and hippocampus and the interleukin (il)-10 and bdnf levels in the pfc, and these effects were prevented by urb597. |
2020-09-28 |
2023-08-13 |
rat |
| Nathaniel Bohm-Levine, Alexander R Goldberg, Monica Mariani, Maya Frankfurt, Janice Thornto. Reducing luteinizing hormone levels after ovariectomy improves spatial memory: Possible role of brain-derived neurotrophic factor. Hormones and behavior. vol 118. 2020-09-28. PMID:31593698. |
estrogens appear to exert some of their effects on memory by increasing levels of brain-derived neurotrophic factor (bdnf) in the hippocampus. |
2020-09-28 |
2023-08-13 |
human |
| Nathaniel Bohm-Levine, Alexander R Goldberg, Monica Mariani, Maya Frankfurt, Janice Thornto. Reducing luteinizing hormone levels after ovariectomy improves spatial memory: Possible role of brain-derived neurotrophic factor. Hormones and behavior. vol 118. 2020-09-28. PMID:31593698. |
immunohistochemical analysis revealed that both antide and estradiol increased bdnf expression in the hippocampus. |
2020-09-28 |
2023-08-13 |
human |
| Nathaniel Bohm-Levine, Alexander R Goldberg, Monica Mariani, Maya Frankfurt, Janice Thornto. Reducing luteinizing hormone levels after ovariectomy improves spatial memory: Possible role of brain-derived neurotrophic factor. Hormones and behavior. vol 118. 2020-09-28. PMID:31593698. |
these results provide evidence for a relationship between lh and bdnf in the hippocampus and demonstrate that estrogen-increasing and lh-lowering treatments may both require bdnf signaling in order to improve spatial memory. |
2020-09-28 |
2023-08-13 |
human |
| Maryam Hoseindoost, Mohammad Reza Alipour, Fereshteh Farajdokht, Roghayeh Diba, Parvin Bayandor, Keyvan Mehri, Sepehr Nayebi Rad, Shirin Babr. Effects of troxerutin on inflammatory cytokines and BDNF levels in male offspring of high-fat diet fed rats. Avicenna journal of phytomedicine. vol 9. issue 6. 2020-09-28. PMID:31763218. |
in the present study, we aimed to examine the effect of troxerutin treatment on levels of brain-derived neurotrophic factor (bdnf), and tumor necrosis factor-alpha (tnf-α) and interleukin-6 (il-6), as pro-inflammatory cytokines, in the blood and hippocampus of high-fat diet (hfd) fed dams and their male offspring. |
2020-09-28 |
2023-08-13 |
rat |
| Gyeong Joon Moon, Sehwan Kim, Min-Tae Jeon, Kea Joo Lee, Il-Sung Jang, Michiko Nakamura, Sang Ryong Ki. Therapeutic Potential of AAV1-Rheb(S16H) Transduction Against Alzheimer's Disease. Journal of clinical medicine. vol 8. issue 12. 2020-09-28. PMID:31766645. |
rheb(s16h) transduction of hippocampal neurons in the 5xfad mice increased the levels of neurotrophic signaling molecules, including brain-derived neurotrophic factor (bdnf) and ciliary neurotrophic factor (cntf), and their corresponding receptors, tropomyosin receptor kinase b (trkb) and cntf receptor α subunit (cntfrα), respectively. |
2020-09-28 |
2023-08-13 |
mouse |
| Anna O Giarratana, Shavonne Teng, Sahithi Reddi, Cynthia Zheng, Derek Adler, Smita Thakker-Varia, Janet Alde. BDNF Val66Met Genetic Polymorphism Results in Poor Recovery Following Repeated Mild Traumatic Brain Injury in a Mouse Model and Treatment With AAV-BDNF Improves Outcomes. Frontiers in neurology. vol 10. 2020-09-28. PMID:31787925. |
in order to determine the mechanism for these differences, we investigated levels of the apoptotic-inducing pro bdnf and survival-inducing mature bdnf isoforms and found that met carriers had less total bdnf in the cortex and a higher pro/mature ratio of bdnf in the hippocampus. |
2020-09-28 |
2023-08-13 |
mouse |
| Bo Dam Lee, Jae-Myung Yoo, Seong Yeon Baek, Fu Yi Li, Dai-Eun Sok, Mee Ree Ki. 3,3'-Diindolylmethane Promotes BDNF and Antioxidant Enzyme Formation via TrkB/Akt Pathway Activation for Neuroprotection against Oxidative Stress-Induced Apoptosis in Hippocampal Neuronal Cells. Antioxidants (Basel, Switzerland). vol 9. issue 1. 2020-09-28. PMID:31861353. |
3,3'-diindolylmethane promotes bdnf and antioxidant enzyme formation via trkb/akt pathway activation for neuroprotection against oxidative stress-induced apoptosis in hippocampal neuronal cells. |
2020-09-28 |
2023-08-13 |
mouse |
| Yang Zong, Ting Chen, Hongli Dong, Lijing Zhu, Wenzheng J. Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009949. |
furthermore, the key proteins nf-κb, bdnf, and trkb were analyzed by western blot (wb) analysis in the hippocampus. |
2020-09-28 |
2023-08-13 |
rat |
| Yang Zong, Ting Chen, Hongli Dong, Lijing Zhu, Wenzheng J. Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009949. |
the levels of nf-κb, bdnf, and trkb in the hippocampus of depressive rats were also altered. |
2020-09-28 |
2023-08-13 |
rat |
| Ke Fang, Hua-Rong Li, Xing-Xing Chen, Xin-Ran Gao, Ling-Ling Huang, An-Qi Du, Chuan Jiang, Hua Li, Jin-Fang G. Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009956. |
results of western blot showed that the expression levels of bdnf, copine 6, p-trkb, and the triggering receptors expressed on myeloid cells (trem) 1 were decreased in both the hippocampus and the prefrontal cortex (pfc) of lps-challenged rats, while the expression of trem2 was increased. |
2020-09-28 |
2023-08-13 |
mouse |
| Osvaldo Flores-Bastías, Alfredo Adriasola-Carrasco, Eduardo Karahania. Activation of Melanocortin-4 Receptor Inhibits Both Neuroinflammation Induced by Early Exposure to Ethanol and Subsequent Voluntary Alcohol Intake in Adulthood in Animal Models: Is BDNF the Key Mediator? Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32063838. |
we hypothesize that ethanol exposure during adolescence decreases the expression of α-msh and hence mc4r signaling in the hippocampus, leading to a lower bdnf activity that causes dramatic changes in the brain (e.g., neuroinflammation and decreased neurogenesis) that predispose to maintain alcohol abuse until adulthood. |
2020-09-28 |
2023-08-13 |
rat |
| Christoph Linnemann, Undine E Lan. Pathways Connecting Late-Life Depression and Dementia. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32231570. |
fourthly, the neurotrophin bdnf is highly expressed in the central nervous system, especially in the hippocampus, where it plays a key role in the proliferation, differentiation and the maintenance of neuronal integrity throughout lifespan. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dongyoung Yun, Min-Tae Jeon, Hyung-Jun Kim, Gyeong Joon Moon, Shinrye Lee, Chang Man Ha, Minsang Shin, Sang Ryong Ki. Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus Experimental neurobiology. vol 29. issue 2. 2020-09-28. PMID:32408406. |
herein, we report that hippocampal transduction of adeno-associated virus serotype 1 (aav1) with a constitutively active form of ras homolog enriched in brain [rheb(s16h)], which can stimulate the production of brain-derived neurotrophic factor (bdnf) in hippocampal neurons, induces the increases in expression of gdnf and gdnf family receptor α-1 (gfrα-1), in neurons and astrocytes in the hippocampus of rat brain |
2020-09-28 |
2023-08-13 |
rat |
| Quentin Delmotte, Diabe Diabira, Yasmine Belaidouni, Mira Hamze, Marine Kochmann, Aurélie Montheil, Jean-Luc Gaiarsa, Christophe Porcher, Yesser H Belgace. Sonic Hedgehog Signaling Agonist (SAG) Triggers BDNF Secretion and Promotes the Maturation of GABAergic Networks in the Postnatal Rat Hippocampus. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32425757. |
sonic hedgehog signaling agonist (sag) triggers bdnf secretion and promotes the maturation of gabaergic networks in the postnatal rat hippocampus. |
2020-09-28 |
2023-08-13 |
rat |