| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Zong, Ting Chen, Hongli Dong, Lijing Zhu, Wenzheng J. Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009949. |
furthermore, the key proteins nf-κb, bdnf, and trkb were analyzed by western blot (wb) analysis in the hippocampus. |
2020-09-28 |
2023-08-13 |
rat |
| Yang Zong, Ting Chen, Hongli Dong, Lijing Zhu, Wenzheng J. Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009949. |
the levels of nf-κb, bdnf, and trkb in the hippocampus of depressive rats were also altered. |
2020-09-28 |
2023-08-13 |
rat |
| Ke Fang, Hua-Rong Li, Xing-Xing Chen, Xin-Ran Gao, Ling-Ling Huang, An-Qi Du, Chuan Jiang, Hua Li, Jin-Fang G. Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32009956. |
results of western blot showed that the expression levels of bdnf, copine 6, p-trkb, and the triggering receptors expressed on myeloid cells (trem) 1 were decreased in both the hippocampus and the prefrontal cortex (pfc) of lps-challenged rats, while the expression of trem2 was increased. |
2020-09-28 |
2023-08-13 |
mouse |
| Osvaldo Flores-Bastías, Alfredo Adriasola-Carrasco, Eduardo Karahania. Activation of Melanocortin-4 Receptor Inhibits Both Neuroinflammation Induced by Early Exposure to Ethanol and Subsequent Voluntary Alcohol Intake in Adulthood in Animal Models: Is BDNF the Key Mediator? Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32063838. |
we hypothesize that ethanol exposure during adolescence decreases the expression of α-msh and hence mc4r signaling in the hippocampus, leading to a lower bdnf activity that causes dramatic changes in the brain (e.g., neuroinflammation and decreased neurogenesis) that predispose to maintain alcohol abuse until adulthood. |
2020-09-28 |
2023-08-13 |
rat |
| Christoph Linnemann, Undine E Lan. Pathways Connecting Late-Life Depression and Dementia. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32231570. |
fourthly, the neurotrophin bdnf is highly expressed in the central nervous system, especially in the hippocampus, where it plays a key role in the proliferation, differentiation and the maintenance of neuronal integrity throughout lifespan. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dongyoung Yun, Min-Tae Jeon, Hyung-Jun Kim, Gyeong Joon Moon, Shinrye Lee, Chang Man Ha, Minsang Shin, Sang Ryong Ki. Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus Experimental neurobiology. vol 29. issue 2. 2020-09-28. PMID:32408406. |
herein, we report that hippocampal transduction of adeno-associated virus serotype 1 (aav1) with a constitutively active form of ras homolog enriched in brain [rheb(s16h)], which can stimulate the production of brain-derived neurotrophic factor (bdnf) in hippocampal neurons, induces the increases in expression of gdnf and gdnf family receptor α-1 (gfrα-1), in neurons and astrocytes in the hippocampus of rat brain |
2020-09-28 |
2023-08-13 |
rat |
| Quentin Delmotte, Diabe Diabira, Yasmine Belaidouni, Mira Hamze, Marine Kochmann, Aurélie Montheil, Jean-Luc Gaiarsa, Christophe Porcher, Yesser H Belgace. Sonic Hedgehog Signaling Agonist (SAG) Triggers BDNF Secretion and Promotes the Maturation of GABAergic Networks in the Postnatal Rat Hippocampus. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32425757. |
sonic hedgehog signaling agonist (sag) triggers bdnf secretion and promotes the maturation of gabaergic networks in the postnatal rat hippocampus. |
2020-09-28 |
2023-08-13 |
rat |
| John R Kershne. Dyslexia as an adaptation to cortico-limbic stress system reactivity. Neurobiology of stress. vol 12. 2020-09-28. PMID:32435671. |
stress exceeding an individual's range of resilience: (1) reduces levels of tfeb and bdnf, gene regulatory factors prolonging maturation and neuroplasticity; (2) interferes with the insular cortex, amygdala and hippocampus in coordinating afferent visceral signals with cognitive performance; (3) over-recruits the brain's default mode network; and (4) amplifies release from the locus coeruleus/norepinephrine system which impairs the entrainment of oscillations in the lower phonological frequencies of speech. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jonathas Rodrigo Dos Santos, Mariza Bortolanza, Gustavo Duarte Ferrari, Guilherme Pauperio Lanfredi, Glauce Crivelaro do Nascimento, Ana Elisa Calereiro Seixas Azzolini, Elaine Del Bel, Alline Cristina de Campos, Vitor Marcel Faça, Anderson Vulczak, Luciane Carla Alberic. One-Week High-Intensity Interval Training Increases Hippocampal Plasticity and Mitochondrial Content without Changes in Redox State. Antioxidants (Basel, Switzerland). vol 9. issue 5. 2020-09-28. PMID:32455608. |
the mass spectrometry analyses showed that one-week of hiit increased minichromosome maintenance complex component 2 (mcm2), brain derived neutrophic factor (bdnf), doublecortin (dcx) and voltage-dependent anion-selective channel protein 2 (vdac), and decreased mitochondrial superoxide dismutase 2 (sod 2) in the hippocampus. |
2020-09-28 |
2023-08-13 |
mouse |
| Shanyan Hong, Honghong Huang, Meili Yang, Haining Wu, Lingxing Wan. Enriched Environment Decreases Cognitive Impairment in Elderly Rats With Prenatal Mobile Phone Exposure. Frontiers in aging neuroscience. vol 12. 2020-09-28. PMID:32581772. |
the results demonstrated that prenatal long-term but not short-term exposure to mobile phone lead to cognitive impairment, morphological changes in the hippocampal cells, reduced synaptic number, decreased syn, psd-95, and bdnf expression in elderly offspring, which were alleviated by postnatal ee housing. |
2020-09-28 |
2023-08-13 |
rat |
| Yabei Song, Caiyun Cao, Qiuyue Xu, Simeng Gu, Fushun Wang, Xi Huang, Shijun Xu, Erxi Wu, Jason H Huan. Piperine Attenuates TBI-Induced Seizures via Inhibiting Cytokine-Activated Reactive Astrogliosis. Frontiers in neurology. vol 11. 2020-09-28. PMID:32655468. |
our data show that piperine treatment can reduce the degree of cerebral edema, down-regulate tnf-α, il-1β, and bdnf, decrease the reactivity of gfap in the hippocampus, and inhibit tbi-induced seizures. |
2020-09-28 |
2023-08-13 |
mouse |
| Tae-Woon Kim, Sang-Seo Park, Mal-Soon Shin, Hye-Sang Park, Seung-Soo Bae. Treadmill exercise ameliorates social isolation-induced memory impairment by enhancing silent information regulator-1 expression in rats. Journal of exercise rehabilitation. vol 16. issue 3. 2020-09-28. PMID:32724779. |
hippocampal bdnf and trkb expression was decreased in the rats of social isolation group. |
2020-09-28 |
2023-08-13 |
rat |
| Jianxin Li, Ling Chen, Gaowen Li, Xiaojuan Chen, Sisi Hu, Liang Zheng, Victor Luria, Jinpeng Lv, Yindi Sun, Ying Xu, Yingcong Y. Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32733195. |
our previous study suggested that acute treatment with a novel curcumin derivative j147 exhibited antidepressant-like effects by increasing brain derived neurotrophic factor (bdnf) level in the hippocampus of mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Andrzej Wróbel, Anna Serefko, Aleksandra Szopa, Daniela Ulrich, Ewa Poleszak, Tomasz Rechberge. O-1602, an Agonist of Atypical Cannabinoid Receptors GPR55, Reverses the Symptoms of Depression and Detrusor Overactivity in Rats Subjected to Corticosterone Treatment. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32733244. |
the o-1602 treatment also reversed the abnormal changes in the bladder, hippocampal or urine values of cgrp, oct3, vacht, bdnf, and ngf. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
effects of vortioxetine on depression model rats and expression of bdnf and trk b in hippocampus. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
effects of vortioxetine on the expression of brain-derived neurotrophic factor (bdnf) and tyrosine kinase b (trk b) in hippocampus of depressive rats were investigated. |
2020-09-28 |
2023-08-13 |
rat |
| Baomin Sun, Yanhua Lv, Hua Xu, Chunhua Qi, Cuiping Li, Pengfei Li. Effects of Vortioxetine on depression model rats and expression of BDNF and Trk B in hippocampus. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765787. |
the expression of bdnf and trk b in rat hippocampus was detected by enzyme-linked immuno sorbent assay. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
sevoflurane reduced brain-derived neurotrophic factor (bdnf), acetyl histone h3 (ac-h3), and ac-h4 levels and increased histone deacetylases-2 (hdac2) and hdac3 levels in the hippocampus of the offspring on postnatal day 1 (p1) and p35. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
ee alleviated sevoflurane-induced cognitive dysfunction and increased hippocampal bdnf, ac-h3, and ac-h4. |
2020-09-28 |
2023-08-13 |
rat |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
exposure to 2.5% sevoflurane for 3 h during late-pregnancy decreased hippocampal bdnf, ac-h3, and ac-h4 in the offspring but had no effect on cognitive function. |
2020-09-28 |
2023-08-13 |
rat |