| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Yu, Jianxiong Jian. COX-2/PGE Epilepsia open. vol 5. issue 3. 2020-09-28. PMID:32913950. |
cox-2/pge the objective of this study was to identify the signaling pathway that is immediately triggered by status epilepticus (se) and in turn contributes to the excessive brain-derived neurotrophic factor (bdnf)/tropomyosin-related kinase receptor b (trkb) signaling within the hippocampus. |
2020-09-28 |
2023-08-13 |
Not clear |
| Henry M Corpuz, Hiroshi Fujii, Soichiro Nakamura, Shigeru Katayam. Fermented rice peptides attenuate scopolamine-induced memory impairment in mice by regulating neurotrophic signaling pathways in the hippocampus. Brain research. vol 1720. 2020-09-24. PMID:31278934. |
frp pretreatment suppressed scopolamine-induced cognitive impairment in passive-avoidance test and significantly upregulated levels of brain-derived neurotrophic factor (bdnf) and induced the phosphorylation of camp response element binding (creb) protein and extracellular signal-regulated kinase (erk) in the hippocampus of scopolamine-treated mice. |
2020-09-24 |
2023-08-13 |
mouse |
| Tahereh Ghadiri, Gelareh Vakilzadeh, Vahid Hajali, Fariba Khodaghol. Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus. Neuroscience letters. vol 709. 2020-09-24. PMID:31325580. |
in line with behavioral alterations, 32 mg/kg progesterone enhanced the amount of nrf2 and ho-1 proteins and decreased the level of nf-kb, bdnf, caspase 3 and ratio of bax/bcl-2 in the ipsilateral hippocampus. |
2020-09-24 |
2023-08-13 |
rat |
| Julieta Paola Aguggia, Marta Magdalena Suárez, María Angélica Rivarol. Multiparity Dampened the Neurobehavioral Consequences of Mother-Pup Separation Stress in Dams. Neuroscience. vol 416. 2020-09-24. PMID:31377452. |
cell survival and proliferation in the dentate gyrus, as well as bdnf expression in the hippocampus, were evaluated by immunohistochemistry as possible candidates for mediating brain plasticity in response to reproductive experience and stress. |
2020-09-24 |
2023-08-13 |
rat |
| Ethiane Segabinazi, Christiano Spindler, André Luís Ferreira de Meireles, Francele Valente Piazza, Filipe Mega, Gabriela Dos Santos Salvalaggio, Matilde Achaval, Simone Marcuzz. Effects of Maternal Physical Exercise on Global DNA Methylation and Hippocampal Plasticity of Rat Male Offspring. Neuroscience. vol 418. 2020-09-24. PMID:31473277. |
at p53, hippocampal global dna methylation, survival of progenitor cells (brdu), brain-derived neurotrophic factor (bdnf) and reelin levels were measured. |
2020-09-24 |
2023-08-13 |
rat |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the bdnf signalling pathway and neurogenesis in the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
in addition, an impairment in hippocampal neurogenesis that paralleled a reduced bdnf level in the hippocampus was observed in the mice that were subjected with csds for 3 weeks, while treatment with ds reversed these changes. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
moreover, ds treatment significantly upregulated bdnf, ptrkb/trkb, pakt/akt, ppi3k/pi3k, pcreb/creb, perk1/2/erk1/2 and pmtor/mtor protein expression in the hippocampus. |
2020-09-24 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Cong Lu, Qiong Wang, Tian-Ji Xia, Yu Bao, Shan-Shan Li, Xin-Min Li. Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus. Brain research bulletin. vol 153. 2020-09-24. PMID:31542427. |
in conclusion, our results showed that ds exerts antidepressant-like effects in mice with csds-induced depression, that the effects may be mediated by the normalization of monoamine neurotransmitter levels, the prevention of hpa axis dysfunction and the impairment of hippocampal neurogenesis, and that this occurs partly through the ability of ds to enhance bdnf expression by increasing the trkb/creb/erk pathway and the pi3k/akt/mtor pathway. |
2020-09-24 |
2023-08-13 |
mouse |
| Javad Riyahi, Behrouz Abdoli, Abbas Haghparast, Laura Petrosin. Intergenerational effect of parental spatial training on offspring learning: Evidence for sex differences in memory function. Brain research bulletin. vol 153. 2020-09-24. PMID:31585156. |
also, erk1/2, bdnf, syt1 and h3k14ac levels in the hippocampus of offspring were analyzed. |
2020-09-24 |
2023-08-13 |
Not clear |
| Javad Riyahi, Behrouz Abdoli, Abbas Haghparast, Laura Petrosin. Intergenerational effect of parental spatial training on offspring learning: Evidence for sex differences in memory function. Brain research bulletin. vol 153. 2020-09-24. PMID:31585156. |
we observed that father's spatial training increased acetylated h3k14 in male offspring's hippocampus, suggesting that histone acetylation may upregulate the expression of bdnf and phosphorylated erk1/2 in the male offspring of father trained and thus contribute to the enhancement of spatial learning and memory. |
2020-09-24 |
2023-08-13 |
Not clear |
| Daniela Velasquez de Oliveira, Tuany Caroline Bernardi, Silvana Regina de Melo, Jacqueline Godinho, Rúbia Maria Weffort de Oliveira, Humberto Milan. Postischemic fish oil treatment restores dendritic integrity and synaptic proteins levels after transient, global cerebral ischemia in rats. Journal of chemical neuroanatomy. vol 101. 2020-09-22. PMID:31499173. |
the neun and bdnf protein levels were reduced in both the hippocampus and pfc, which were recovered by fo treatment. |
2020-09-22 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Antidepressant effects of moxidectin, an antiparasitic drug, in a rat model of depression. Behavioural brain research. vol 376. 2020-09-22. PMID:31513828. |
we undertook this study to determine whether mox would actually show antidepressant-like properties in an animal model of depression and whether it would affect the hippocampal and frontal cortex levels of brain-derived neurotrophic factor (bdnf) or tumor necrosis factor (tnf)-alpha, peptides that have been implicated in pathogenesis of depression and effectiveness of various antidepressants. |
2020-09-22 |
2023-08-13 |
rat |
| Bruk Getachew, Yousef Tizab. Antidepressant effects of moxidectin, an antiparasitic drug, in a rat model of depression. Behavioural brain research. vol 376. 2020-09-22. PMID:31513828. |
concomitant with the 24 h behavioral effects, the levels of hippocampal and frontal cortical bdnf were significantly increased, whereas the levels of tnf-alpha in both these areas were significantly decreased. |
2020-09-22 |
2023-08-13 |
rat |
| Jusik Park, Wookwang Cheon, Kijin Ki. Effects of Long-Term Endurance Exercise and Lithium Treatment on Neuroprotective Factors in Hippocampus of Obese Rats. International journal of environmental research and public health. vol 17. issue 9. 2020-09-22. PMID:32397675. |
to investigate the effects of long-term lithium treatment and low intensity endurance exercise on brain-derived neurotrophic factor (bdnf) expression and glycogen synthase kinase 3 beta (gsk3β) activity in the hippocampus of obese rats. |
2020-09-22 |
2023-08-13 |
rat |
| Abeer M Rababa'h, Afrah N Mardini, Karem H Alzoubi, Mera A Ababneh, Rabaa Y Athamne. The effect of cilostazol on hippocampal memory and oxidative stress biomarkers in rat model of diabetes mellitus. Brain research. vol 1715. 2020-09-18. PMID:30914251. |
bdnf protein, tbars levels and different antioxidant biomarkers were assessed after dissection of the hippocampus. |
2020-09-18 |
2023-08-13 |
rat |
| Can Sun, Jian Fu, Zhenzhen Qu, Dongxiao Li, Peipei Si, Qi Qiao, Wenlin Zhang, Yan Xue, Junli Zhen, Weiping Wan. Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats. Brain research. vol 1714. 2020-09-17. PMID:30768929. |
moreover, mild hypoxia reversed the suppression of hippocampal neurogenesis and the downregulation of nt-3 and bdnf expression in hippocampus and cortex of epileptic rats. |
2020-09-17 |
2023-08-13 |
rat |
| Bruno Lima Giacobbo, Betânia Souza de Freitas, Kelem Vedovelli, Lívia Machado Schlemmer, Vivian Naziaseno Pires, Vinicius Antoniazzi, Cristophod de Souza Dos Santos, Leticia Paludo, Juliano Viana Borges, Daiane Borba de Lima, Nadja Schröder, Erik F J de Vries, Elke Bromber. Long-term environmental modifications affect BDNF concentrations in rat hippocampus, but not in serum. Behavioural brain research. vol 372. 2020-09-17. PMID:31125621. |
long-term environmental modifications affect bdnf concentrations in rat hippocampus, but not in serum. |
2020-09-17 |
2023-08-13 |
rat |
| Luiza P Géa, Rafael Colombo, Eduarda D da Rosa, Bárbara Antqueviezc, Érica Z de Aguiar, Gabriel Henrique Hizo, Gabriela Barella Schmidt, Larissa F de Oliveira, Dirson João Stein, Adriane R Ros. Anhedonic-like behavior correlates with IFNγ serum levels in a two-hit model of depression. Behavioural brain research. vol 373. 2020-09-14. PMID:31284015. |
brain-derived neurotrophic factor (bdnf) levels were decreased in the serum of cums + animals, while no differences were found in the hippocampus and on lipid peroxidation levels. |
2020-09-14 |
2023-08-13 |
rat |
| Gustavo C Dal-Pont, Marco T S Jório, Wilson R Resende, Fernanda F Gava, Jorge M Aguiar-Geraldo, Taise Possamai-Della, Jefté Peper-Nascimento, João Quevedo, Samira S Valvassor. Effects of lithium and valproate on behavioral parameters and neurotrophic factor levels in an animal model of mania induced by paradoxical sleep deprivation. Journal of psychiatric research. vol 119. 2020-09-14. PMID:31574363. |
psd decreased bdnf, ngf, and gdnf levels in the frontal cortex and hippocampus of mice. |
2020-09-14 |
2023-08-13 |
mouse |