| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Man-Man Zong, Zhi-Qiang Zhou, Mu-Huo Ji, Min Jia, Hui Tang, Jian-Jun Yan. Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31354429. |
the levels of hippocampal β2-ar, proinflammatory cytokines tumor necrosis factor (tnf-α), interleukin-1β (il-1β), il-6, camp-response element binding protein (creb), brain derived neurotrophic factor (bdnf), post-synaptic density protein 95 (psd95), and nmda receptor 2 b subtypes (glun2b) were determined at 6, 12, 24 h and 7 and 16 days after clp. |
2020-09-30 |
2023-08-13 |
mouse |
| Rocío Beatriz Foltran, Karen Melany Stefani, Antonela Bonafina, Agustina Resasco, Silvina Laura Dia. Differential Hippocampal Expression of BDNF Isoforms and Their Receptors Under Diverse Configurations of the Serotonergic System in a Mice Model of Increased Neuronal Survival. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31555094. |
differential hippocampal expression of bdnf isoforms and their receptors under diverse configurations of the serotonergic system in a mice model of increased neuronal survival. |
2020-09-30 |
2023-08-13 |
mouse |
| Rocío Beatriz Foltran, Karen Melany Stefani, Antonela Bonafina, Agustina Resasco, Silvina Laura Dia. Differential Hippocampal Expression of BDNF Isoforms and Their Receptors Under Diverse Configurations of the Serotonergic System in a Mice Model of Increased Neuronal Survival. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31555094. |
in particular, the brain-derived neurotrophic factor, bdnf, is highly expressed in the hippocampus (hc) of rodents and participates in the control of neuronal proliferation, and survival in the dentate gyrus (dg). |
2020-09-30 |
2023-08-13 |
mouse |
| Haiying Dong, Weiliang Cong, Xiwen Guo, Yuhua Wang, Shengju Tong, Qiang Li, Chengchong L. β-asarone relieves chronic unpredictable mild stress induced depression by regulating the extracellular signal-regulated kinase signaling pathway. Experimental and therapeutic medicine. vol 18. issue 5. 2020-09-30. PMID:31616508. |
β-asarone was also found to enhance creb, bdnf, trk-b and bcl-2 levels, and reduce bad level in the hippocampus of cums-treated rats. |
2020-09-30 |
2023-08-13 |
rat |
| Haixia Wang, Ning Jiang, Jingwei Lv, Hong Huang, Xinmin Li. Ginsenoside Rd reverses cognitive deficits by modulating BDNF-dependent CREB pathway in chronic restraint stress mice. Life sciences. vol 258. 2020-09-30. PMID:32682919. |
meanwhile, grd treatment could reverse crs-induced the decrease in phosphorylated phosphoinositide 3-kinase (pi3k), camp-reflecting element binding protein (creb), brain-derived neurotrophic factor (bdnf) and tyrosine kinase b (trkb) expression in the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Efstathios Garoflos, Theofanis Panagiotaropoulos, Stavroula Pondiki, Antonios Stamatakis, Eleni Philippidis, Fotini Stylianopoulo. Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states. Annals of general psychiatry. vol 4. 2020-09-29. PMID:15876359. |
in the present study we investigated the effects of neonatal handling, an animal model of early experience, on spatial learning and memory, on hippocampal glucocorticoid (gr), mineralocorticoid (mr) and type 1a serotonin (5-ht1a) receptors, as well as brain derived neurotrophic factor (bdnf), and on circulating leptin levels, of male rats. |
2020-09-29 |
2023-08-12 |
rat |
| Qiaoer Su, Yifan Cheng, Kunlin Jin, Jianhua Cheng, Yuanshao Lin, Zhenzhen Lin, Liuqing Wang, Bei Sha. Estrogen therapy increases BDNF expression and improves post-stroke depression in ovariectomy-treated rats. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602095. |
increased brain-derived neurotrophic factor (bdnf) expression was reported in the hippocampus of rats that had been treated with estrogen for two weeks, suggesting that bdnf expression may be an important contributor to the improvement of post-stroke depression that is observed following estrogen therapy. |
2020-09-29 |
2023-08-13 |
rat |
| Shahla Shojaei, Mohammad Reza Panjehshahin, Sayed Mohammad Shafiee, Zahra Khoshdel, Mohammad Borji, Ghasem Ghasempour, Ali Akbar Owj. Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain. Iranian journal of medical sciences. vol 42. issue 1. 2020-09-29. PMID:28293048. |
the induction of brain-derived neurotrophic factor (bdnf) expression in the hippocampus has shown to play a role in the beneficial effects of resveratrol (rsv) on the learning and memory. |
2020-09-29 |
2023-08-13 |
rat |
| Shahla Shojaei, Mohammad Reza Panjehshahin, Sayed Mohammad Shafiee, Zahra Khoshdel, Mohammad Borji, Ghasem Ghasempour, Ali Akbar Owj. Differential Effects of Resveratrol on the Expression of Brain-Derived Neurotrophic Factor Transcripts and Protein in the Hippocampus of Rat Brain. Iranian journal of medical sciences. vol 42. issue 1. 2020-09-29. PMID:28293048. |
estrogens increase levels of bdnf transcripts in the hippocampus of rats. |
2020-09-29 |
2023-08-13 |
rat |
| Milene L Brownlow, Seung H Jung, Raquel J Moore, Naomi Bechmann, Ryan Jankor. Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments. Frontiers in molecular neuroscience. vol 10. 2020-09-29. PMID:28555095. |
stress-induced decrease in hippocampal levels of β-hydroxybutyrate was attenuated in kd group while both kd and ks prevented stress effects on bdnf levels. |
2020-09-29 |
2023-08-13 |
human |
| Shanghua Fan, Zheman Xiao, Fan Zhu, Xiaohua He, Zuneng L. A new comorbidity model and the common pathological mechanisms of migraine and epilepsy. American journal of translational research. vol 9. issue 5. 2020-09-29. PMID:28559979. |
the expression of brain-derived neurotrophic factor (bdnf) in the ca3 area of the hippocampus in the comorbidity group was significantly higher than that in the epilepsy group according to the immunohistochemical test (p<0.05). |
2020-09-29 |
2023-08-13 |
rat |
| Toshiyuki Mizui, Koji Ohira, Masami Kojim. BDNF pro-peptide: a novel synaptic modulator generated as an N-terminal fragment from the BDNF precursor by proteolytic processing. Neural regeneration research. vol 12. issue 7. 2020-09-29. PMID:28852376. |
unexpectedly, we found that the pro-domain (or pro-peptide) of brain-derived neurotrophic factor (bdnf), which is well-known neurotrophic factor in brain, has a potential ability to facilitate hippocampal long-term depression. |
2020-09-29 |
2023-08-13 |
Not clear |
| Taro Kishi, Reiji Yoshimura, Toshikazu Ikuta, Nakao Iwat. Brain-Derived Neurotrophic Factor and Major Depressive Disorder: Evidence from Meta-Analyses. Frontiers in psychiatry. vol 8. 2020-09-29. PMID:29387021. |
our findings indicated that the val66met polymorphism in the bdnf gene was not associated with mdd or hippocampal volume in patients with mdd. |
2020-09-29 |
2023-08-13 |
Not clear |
| Albert Batalla, Valentina Lorenzetti, Yann Chye, Murat Yücel, Carles Soriano-Mas, Sagnik Bhattacharyya, Marta Torrens, José A S Crippa, Rocío Martín-Santo. The Influence of DAT1, COMT, and BDNF Genetic Polymorphisms on Total and Subregional Hippocampal Volumes in Early Onset Heavy Cannabis Users. Cannabis and cannabinoid research. vol 3. issue 1. 2020-09-29. PMID:29404409. |
the influence of dat1, comt, and bdnf genetic polymorphisms on total and subregional hippocampal volumes in early onset heavy cannabis users. |
2020-09-29 |
2023-08-13 |
Not clear |
| Wen-Cheng Lu, Yu-Xiao Zhou, Ping Qiao, Jin Zheng, Qiang Wu, Qiang She. The protocadherin alpha cluster is required for axon extension and myelination in the developing central nervous system. Neural regeneration research. vol 13. issue 3. 2020-09-29. PMID:29623926. |
rna sequencing of hippocampal e17.5 rna showed that expression levels of bdnf, fmod, nrp2, ogn, and sema3d, which are associated with axon extension, were significantly down-regulated in the absence of the pcdhα gene cluster. |
2020-09-29 |
2023-08-13 |
mouse |
| Huili Jiang, Xuhui Zhang, Jun Lu, Hong Meng, Yang Sun, Xinjing Yang, Bingcong Zhao, Tuya Ba. Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29636708. |
the expression of serum bdnf was detected by enzyme-linked immunosorbent assay (elisa), the hippocampal bdnf, acetylation levels in histone h3 lysine 9 (ach3k9), and hdac2 by western blot, the hippocampal mrna of bdnf by rt-polymerase chain reaction (pcr). |
2020-09-29 |
2023-08-13 |
rat |
| Huili Jiang, Xuhui Zhang, Jun Lu, Hong Meng, Yang Sun, Xinjing Yang, Bingcong Zhao, Tuya Ba. Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29636708. |
we investigated that the expression of bdnf in serum and hippocampus were significantly downregulated compared with controls. |
2020-09-29 |
2023-08-13 |
rat |
| Huili Jiang, Xuhui Zhang, Jun Lu, Hong Meng, Yang Sun, Xinjing Yang, Bingcong Zhao, Tuya Ba. Antidepressant-Like Effects of Acupuncture-Insights From DNA Methylation and Histone Modifications of Brain-Derived Neurotrophic Factor. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29636708. |
notably, acupuncture reversed the downregulation of bdnf in serum and hippocampus and mrna of bdnf compared with model group. |
2020-09-29 |
2023-08-13 |
rat |
| Najmeh Asrari, Rezvan Yazdian-Robati, Khalil Abnous, BiBi Marjan Razavi, Mrazieh Rashednia, Faezeh Vahdati Hasani, Hossein Hosseinzade. Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum. Journal of pharmacopuncture. vol 21. issue 1. 2020-09-29. PMID:30151303. |
the role of bdnf (brain-derived neurotrophic factor), creb (camp response element binding) and vgf neuropeptide has been proved in antidepressant activity of long term saffron administration in the rat hippocampus. |
2020-09-29 |
2023-08-13 |
rat |
| Ai-Hua Xu, Yang Yang, Yong-Xin Sun, Chao-Dong Zhan. Exogenous brain-derived neurotrophic factor attenuates cognitive impairment induced by okadaic acid in a rat model of Alzheimer's disease. Neural regeneration research. vol 13. issue 12. 2020-09-29. PMID:30323150. |
our results indicated that bdnf expression was suppressed in the hippocampus of oa-treated rats, which resulted in learning and memory deficits. |
2020-09-29 |
2023-08-13 |
rat |